| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luciana Uint, Gisele Medeiros Bastos, Helena Strelow Thurow, Jessica Bassani Borges, Thiago Dominguez Crespo Hirata, João Italo Dias França, Mario Hiroyuki Hirata, Amanda Guerra de Moraes Rego Sous. Increased levels of plasma IL-1b and BDNF can predict resistant depression patients. Revista da Associacao Medica Brasileira (1992). vol 65. issue 3. 2019-07-01. PMID:30994834. |
increased levels of plasma il-1b and bdnf can predict resistant depression patients. |
2019-07-01 |
2023-08-13 |
Not clear |
| Amal Chandra Mondal, Mahino Fatim. Direct and indirect evidences of BDNF and NGF as key modulators in depression: role of antidepressants treatment. The International journal of neuroscience. vol 129. issue 3. 2019-06-26. PMID:30235967. |
direct and indirect evidences of bdnf and ngf as key modulators in depression: role of antidepressants treatment. |
2019-06-26 |
2023-08-13 |
Not clear |
| Muzi Li, Carl D'Arcy, Xintong Li, Tieyuan Zhang, Ridha Joober, Xiangfei Men. What do DNA methylation studies tell us about depression? A systematic review. Translational psychiatry. vol 9. issue 1. 2019-06-20. PMID:30718449. |
subgroup analyses showed that most studies found bdnf and slc6a4 hypermethylations to be associated with mdd or depression in general. |
2019-06-20 |
2023-08-13 |
Not clear |
| Abhik Sen, Thomas J Nelson, Daniel L Alkon, Jarin Hongpaisa. Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's disease : JAD. vol 63. issue 3. 2019-06-10. PMID:29710707. |
reciprocally, a depression of pkcɛ reduces bdnf and mnsod, resulting in oxidative stress. |
2019-06-10 |
2023-08-13 |
mouse |
| Alexander Kautzky, Gregory M James, Cecile Philippe, Pia Baldinger-Melich, Christoph Kraus, Georg S Kranz, Thomas Vanicek, Gregor Gryglewski, Annette M Hartmann, Andreas Hahn, Wolfgang Wadsak, Markus Mitterhauser, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression. Translational psychiatry. vol 9. issue 1. 2019-06-10. PMID:30664620. |
epistasis of htr1a and bdnf risk genes alters cortical 5-ht1a receptor binding: pet results link genotype to molecular phenotype in depression. |
2019-06-10 |
2023-08-13 |
Not clear |
| Shiyong Peng, Wenqiang Li, Luxian Lv, Zhongjiang Zhang, Xiping Zha. BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression. Discovery medicine. vol 26. issue 143. 2019-06-03. PMID:30586536. |
bdnf as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression. |
2019-06-03 |
2023-08-13 |
Not clear |
| Shiyong Peng, Wenqiang Li, Luxian Lv, Zhongjiang Zhang, Xiping Zha. BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression. Discovery medicine. vol 26. issue 143. 2019-06-03. PMID:30586536. |
brain-derived neurotrophic factor (bdnf) has appeared to play a critical role in certain neurobiological modifications that may otherwise lead to schizophrenia or depression. |
2019-06-03 |
2023-08-13 |
Not clear |
| Shiyong Peng, Wenqiang Li, Luxian Lv, Zhongjiang Zhang, Xiping Zha. BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression. Discovery medicine. vol 26. issue 143. 2019-06-03. PMID:30586536. |
meta-analyses have demonstrated that serum bdnf levels were tightly correlated with the courses of severe schizophrenia and major depression disorders. |
2019-06-03 |
2023-08-13 |
Not clear |
| Shiyong Peng, Wenqiang Li, Luxian Lv, Zhongjiang Zhang, Xiping Zha. BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression. Discovery medicine. vol 26. issue 143. 2019-06-03. PMID:30586536. |
this article presents a review of bdnf as a neurobiological marker for schizophrenia and depression and for the efficacy of rtms treatments of these mental diseases. |
2019-06-03 |
2023-08-13 |
Not clear |
| Jing Wang, Henrietta Bains, Agustin Anastasia, Clay Bracke. NMR backbone resonance assignments of the prodomain variants of BDNF in the urea denatured state. Biomolecular NMR assignments. vol 12. issue 1. 2019-05-31. PMID:28933046. |
a single val66met variant has been identified in the prodomain of human bdnf that is associated with anxiety, depression and memory disorders. |
2019-05-31 |
2023-08-13 |
human |
| Jun Shen, Yaqing Li, Chujie Qu, Linling Xu, Huimin Sun, Junjian Zhan. The enriched environment ameliorates chronic unpredictable mild stress-induced depressive-like behaviors and cognitive impairment by activating the SIRT1/miR-134 signaling pathway in hippocampus. Journal of affective disorders. vol 248. 2019-05-14. PMID:30716615. |
enriched environment (ee) showed a beneficial effect on depression and cognition by enhancing brain derived neurotrophic factor (bdnf) expression and synaptic plasticity. |
2019-05-14 |
2023-08-13 |
Not clear |
| Akiko Nanri, Takeshi Kochi, Masafumi Eguchi, Isamu Kabe, Tetsuya Mizou. Demographic and lifestyle correlates of brain-derived neurotrophic factor in a working population: The Furukawa Nutrition and Health Study. Psychiatry research. vol 272. 2019-05-08. PMID:30616127. |
in this study, higher bmi and smoking were associated with higher concentrations of serum bdnf, while nutrients that have been linked to depression were not associated with bdnf concentrations among japanese workers. |
2019-05-08 |
2023-08-13 |
human |
| C W Bird, B C Baculis, J J Mayfield, G J Chavez, T Ontiveros, D J Paine, A J Marks, A L Gonzales, D Ron, C F Valenzuel. The brain-derived neurotrophic factor VAL68MET polymorphism modulates how developmental ethanol exposure impacts the hippocampus. Genes, brain, and behavior. vol 18. issue 3. 2019-05-01. PMID:29691979. |
this polymorphism disrupts bdnf's intracellular trafficking and activity-dependent secretion, and has been linked to increased incidence of neuropsychiatric disorders such as depression and anxiety. |
2019-05-01 |
2023-08-13 |
mouse |
| Jian Liu, Han-Xiao Zhu, Wan-Li Fu, Xin-Wei Xu, Jun-Zhe Yang, Dan Dai, Yun L. Downregulated hippocampal expression of brain derived neurotrophic factor and tyrosine kinase B in a rat model of comorbid epilepsy and depression. Neurological research. vol 41. issue 5. 2019-04-18. PMID:30741614. |
to investigate the expression of brain-derived neurotrophic factor(bdnf) and tyrosine kinase b (trkb) protein in the hippocampus of model rats of comorbid epilepsy and depression. |
2019-04-18 |
2023-08-13 |
rat |
| Yong-Ku Kim, Byung-Joo Ham, Kyu-Man Ha. Interactive effects of genetic polymorphisms and childhood adversity on brain morphologic changes in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 91. 2019-04-15. PMID:29535036. |
childhood adversity showed an interaction with the brain-derived neurotrophic factor (bdnf) gene val66met polymorphism, serotonin transporter-linked promoter region (5-httlpr), and fk506 binding protein 51 (fkbp5) gene rs1360780 in brain morphologic changes in patients with depression and in a non-clinical population. |
2019-04-15 |
2023-08-13 |
Not clear |
| Lanwei Hou, Yirui Qi, Hongwei Sun, Gang Wang, Qi Li, Yanyu Wang, Zuoji Zhang, Zhongde Du, Lin Su. Applying ketamine to alleviate the PTSD-like effects by regulating the HCN1-related BDNF. Progress in neuro-psychopharmacology & biological psychiatry. vol 86. 2019-04-15. PMID:29596995. |
post-traumatic stress disorder (ptsd) is commonly associated with concurrent anxiety and depression symptoms, and reduce the expression of the brain-derived neurotrophic factor (bdnf) which promotes the proliferation and survival of neurons. |
2019-04-15 |
2023-08-13 |
Not clear |
| Lanwei Hou, Yirui Qi, Hongwei Sun, Gang Wang, Qi Li, Yanyu Wang, Zuoji Zhang, Zhongde Du, Lin Su. Applying ketamine to alleviate the PTSD-like effects by regulating the HCN1-related BDNF. Progress in neuro-psychopharmacology & biological psychiatry. vol 86. 2019-04-15. PMID:29596995. |
the hyperpolarization-activated cyclic nucleotide-gated channel 1(hcn1) could be inhibited by the ketamine, a drug to alleviate depression and anxiety, and regulated the bdnf expression, however, the effects of ketamine in alleviating ptsd symptoms by regulating the hcn1-related bdnf have been poorly perceived. |
2019-04-15 |
2023-08-13 |
Not clear |
| Hanjie Yu, Dan Lv, Mengxin Shen, Yanhua Zhang, Dongsheng Zhou, Zhongming Chen, Chuang Wan. BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1. Psychiatry research. vol 271. 2019-04-15. PMID:30529315. |
our study provides evidence that scopolamine rapidly attenuates reserpine-induced depression in mice partially by regulating 5-htt, bdnf and tph1 in the hippocampus and pfc of mice. |
2019-04-15 |
2023-08-13 |
mouse |
| Xiang Li, Ming-Min Xu, Hui-Li Jiang, Jun Lu, Xu-Hui Zhang, Bing-Cong Zhao, Xin-Jing Yang, Yang Sun, Xing-Zhou Gao, Xing-Chen Liang, Qiu-Yun Yu, Shi-Xing Feng, Yu-Fei Li, Miao Yu, Ya T. [Effect of Acupuncture Intervention on Depression Behavior and Expression of ERK 1/2 and BDNF in Prefrontal Cortex in Chronic Unpredictable Mild Stress Induced Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 11. 2019-04-08. PMID:30585467. |
[effect of acupuncture intervention on depression behavior and expression of erk 1/2 and bdnf in prefrontal cortex in chronic unpredictable mild stress induced depression rats]. |
2019-04-08 |
2023-08-13 |
rat |
| Xiang Li, Ming-Min Xu, Hui-Li Jiang, Jun Lu, Xu-Hui Zhang, Bing-Cong Zhao, Xin-Jing Yang, Yang Sun, Xing-Zhou Gao, Xing-Chen Liang, Qiu-Yun Yu, Shi-Xing Feng, Yu-Fei Li, Miao Yu, Ya T. [Effect of Acupuncture Intervention on Depression Behavior and Expression of ERK 1/2 and BDNF in Prefrontal Cortex in Chronic Unpredictable Mild Stress Induced Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 11. 2019-04-08. PMID:30585467. |
to investigate the effect of acupuncture intervention on the depression behavior and expression of extracellular signal-regulated protein kinases (erk 1/2), p-erk 1/2 and brain-derived neurotrophic factor (bdnf) in the prefrontal cortex of chronic unpredictable mild stress (cums) induced depression rats, so as to explore its antidepressant mechanism. |
2019-04-08 |
2023-08-13 |
rat |