| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John Marshall, Xiao-Zhong Zhou, Gang Chen, Su-Qing Yang, Ya Li, Yin Wang, Zhi-Qing Zhang, Qin Jiang, Lutz Birnbaumer, Cong Ca. Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 15. 2018-08-24. PMID:29507199. |
stress-related alterations in brain-derived neurotrophic factor (bdnf) expression, a neurotrophin that plays a key role in synaptic plasticity, are believed to contribute to the pathophysiology of depression. |
2018-08-24 |
2023-08-13 |
mouse |
| Mingzhe Zhao, Lu Chen, Jiarun Yang, Dong Han, Deyu Fang, Xiaohui Qiu, Xiuxian Yang, Zhengxue Qiao, Jingsong Ma, Lin Wang, Shixiang Jiang, Xuejia Song, Jiawei Zhou, Jian Zhang, Mingqi Chen, Dong Qi, Yanjie Yang, Hui Pa. BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction. Journal of affective disorders. vol 227. 2018-08-23. PMID:29102837. |
bdnf val66met polymorphism, life stress and depression: a meta-analysis of gene-environment interaction. |
2018-08-23 |
2023-08-13 |
Not clear |
| Mingzhe Zhao, Lu Chen, Jiarun Yang, Dong Han, Deyu Fang, Xiaohui Qiu, Xiuxian Yang, Zhengxue Qiao, Jingsong Ma, Lin Wang, Shixiang Jiang, Xuejia Song, Jiawei Zhou, Jian Zhang, Mingqi Chen, Dong Qi, Yanjie Yang, Hui Pa. BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction. Journal of affective disorders. vol 227. 2018-08-23. PMID:29102837. |
the present meta-analysis aimed to quantify evidence on the interaction between brain-derived neurotrophic factor (bdnf) val66met polymorphism and stress in depression. |
2018-08-23 |
2023-08-13 |
Not clear |
| Tung-Ping Su, Mu-Hong Chen, Cheng-Ta Li, Wei-Chen Lin, Chen-Jee Hong, Ralitza Gueorguieva, Pei-Chi Tu, Ya-Mei Bai, Chih-Ming Cheng, John H Krysta. Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 13. 2018-07-30. PMID:28492279. |
the purpose of this study was to characterize the dose-related antidepressant effects of ketamine in patients with treatment-resistant depression drawn from a chinese population predominately possessing lower activity bdnf genotypes (val/met, met/met). |
2018-07-30 |
2023-08-13 |
Not clear |
| Tung-Ping Su, Mu-Hong Chen, Cheng-Ta Li, Wei-Chen Lin, Chen-Jee Hong, Ralitza Gueorguieva, Pei-Chi Tu, Ya-Mei Bai, Chih-Ming Cheng, John H Krysta. Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 13. 2018-07-30. PMID:28492279. |
this is the first report to our knowledge to demonstrate the dose-related efficacy of r/s-ketamine for treatment-resistant depression and the first to characterize ketamine effects in a genotyped chinese population in which most (83%) patients possessed at least one copy of the lower functioning met allele of the bdnf gene. |
2018-07-30 |
2023-08-13 |
Not clear |
| E Bouvier, F Brouillard, J Molet, D Claverie, J-H Cabungcal, N Cresto, N Doligez, C Rivat, K Q Do, C Bernard, J-J Benoliel, C Becke. Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression. Molecular psychiatry. vol 22. issue 12. 2018-07-10. PMID:27646262. |
our data reveal a novel role for bdnf in controlling redox homeostasis and provide a mechanistic explanation for post-stress vulnerability to depression while suggesting ways to reverse it. |
2018-07-10 |
2023-08-13 |
mouse |
| Maria Skibinska, Pawel Kapelski, Aleksandra Rajewska-Rager, Joanna Pawlak, Aleksandra Szczepankiewicz, Beata Narozna, Joanna Twarowska-Hauser, Monika Dmitrzak-Weglar. Brain-derived neurotrophic factor (BDNF) serum level in women with first-episode depression, correlation with clinical and metabolic parameters. Nordic journal of psychiatry. vol 72. issue 3. 2018-07-10. PMID:29235396. |
bdnf has been implicated in the pathogenesis of psychiatric disorders and its serum level is a potential biomarker for depression. |
2018-07-10 |
2023-08-13 |
Not clear |
| Maria Skibinska, Pawel Kapelski, Aleksandra Rajewska-Rager, Joanna Pawlak, Aleksandra Szczepankiewicz, Beata Narozna, Joanna Twarowska-Hauser, Monika Dmitrzak-Weglar. Brain-derived neurotrophic factor (BDNF) serum level in women with first-episode depression, correlation with clinical and metabolic parameters. Nordic journal of psychiatry. vol 72. issue 3. 2018-07-10. PMID:29235396. |
the aim of this study was to examine serum levels of bdnf in first-episode depression and its correlation with clinical and metabolic parameters. |
2018-07-10 |
2023-08-13 |
Not clear |
| Sriparna Ghosal, Eunyoung Bang, Wenzhu Yue, Brendan D Hare, Ashley E Lepack, Matthew J Girgenti, Ronald S Duma. Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine. Biological psychiatry. vol 83. issue 1. 2018-07-09. PMID:28751069. |
brain-derived neurotrophic factor (bdnf) plays a key role in the pathophysiology and treatment of depression. |
2018-07-09 |
2023-08-13 |
Not clear |
| M Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, M Antonietta Piludu, M Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Expression of BDNF and trkB in the hippocampus of a rat genetic model of vulnerability (Roman low-avoidance) and resistance (Roman high-avoidance) to stress-induced depression. Brain and behavior. vol 7. issue 10. 2018-07-09. PMID:29075579. |
expression of bdnf and trkb in the hippocampus of a rat genetic model of vulnerability (roman low-avoidance) and resistance (roman high-avoidance) to stress-induced depression. |
2018-07-09 |
2023-08-13 |
rat |
| Keshav Gupta, Rachna Gupta, M S Bhatia, A K Tripathi, Lalit K Gupt. Effect of Agomelatine and Fluoxetine on HAM-D Score, Serum Brain-Derived Neurotrophic Factor, and Tumor Necrosis Factor-α Level in Patients With Major Depressive Disorder With Severe Depression. Journal of clinical pharmacology. vol 57. issue 12. 2018-06-29. PMID:28833192. |
this study evaluated the efficacy and tolerability of agomelatine, a melatonergic drug, and fluoxetine (positive comparator) and their effect on serum brain-derived neurotrophic factor (bdnf) and tumor necrosis factor (tnf)-α level in patients having major depressive disorder with severe depression. |
2018-06-29 |
2023-08-13 |
Not clear |
| Vijayakumar Arumugam, Vini Susan John, Nisha Augustine, Taniya Jacob, Sagar Maliakkal Joy, Suchandra Sen, Tuhinadri Se. The impact of antidepressant treatment on brain-derived neurotrophic factor level: An evidence-based approach through systematic review and meta-analysis. Indian journal of pharmacology. vol 49. issue 3. 2018-06-27. PMID:29033483. |
the present systematic review and meta-analysis aim at assessing the influence of antidepressant treatment on bdnf level and the hamilton depression rating scale (hdrs) score, thereby to establish the rationale of utilizing bdnf as a predictive biomarker and hdrs score as an indicator for antidepressant treatment efficacy. |
2018-06-27 |
2023-08-13 |
Not clear |
| Xianpeng Zu, Mingjian Zhang, Wencai Li, Haisheng Xie, Zhang Lin, Niao Yang, Xinru Liu, Weidong Zhan. Antidepressant-like Effect of Bacopaside I in Mice Exposed to Chronic Unpredictable Mild Stress by Modulating the Hypothalamic-Pituitary-Adrenal Axis Function and Activating BDNF Signaling Pathway. Neurochemical research. vol 42. issue 11. 2018-06-26. PMID:28758176. |
taken together, these results indicated that bs-i exhibited an obvious antidepressant-like effect in mouse model of cums-induced depression that was mediated, at least in part, by modulating hpa hyperactivity and activating bdnf signaling pathway. |
2018-06-26 |
2023-08-13 |
mouse |
| Romain Colle, Séverine Trabado, Denis J David, Sylvie Brailly-Tabard, Patrick Hardy, Bruno Falissard, Bruno Fève, Laurent Becquemont, Céline Verstuyft, Emmanuelle Corrubl. Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients. Neuropsychobiology. vol 75. issue 1. 2018-06-25. PMID:28848102. |
plasma bdnf level in major depression: biomarker of the val66met bdnf polymorphism and of the clinical course in met carrier patients. |
2018-06-25 |
2023-08-13 |
Not clear |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena P M Mariyath, Nabeela Khanam, Javier S Castresana, M Mobarak Hossai. Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression. Journal of neuroscience research. vol 96. issue 1. 2018-06-22. PMID:28631844. |
the roles of monoamines, brain-derived neurotrophic factor (bdnf), and wnt signaling are well researched, but sonic hedgehog (shh) signaling and its downstream transcription factor gli1 are not well studied in depression. |
2018-06-22 |
2023-08-13 |
Not clear |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena P M Mariyath, Nabeela Khanam, Javier S Castresana, M Mobarak Hossai. Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression. Journal of neuroscience research. vol 96. issue 1. 2018-06-22. PMID:28631844. |
in this article, we summarize the evidence for the shh signaling pathway in depression and the potential crosstalk of shh with wnt and bdnf. |
2018-06-22 |
2023-08-13 |
Not clear |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena P M Mariyath, Nabeela Khanam, Javier S Castresana, M Mobarak Hossai. Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression. Journal of neuroscience research. vol 96. issue 1. 2018-06-22. PMID:28631844. |
bdnf and wnt signaling are also regulated by various available antidepressants, so there is the possibility that shh may be involved in the pathophysiology of depression. |
2018-06-22 |
2023-08-13 |
Not clear |
| Weerawan Boonlert, Hattaya Benya-Aphikul, Jariya Umka Welbat, Ratchanee Rodsir. Ginseng Extract G115 Attenuates Ethanol-Induced Depression in Mice by Increasing Brain BDNF Levels. Nutrients. vol 9. issue 9. 2018-06-08. PMID:28837087. |
ginseng extract g115 attenuates ethanol-induced depression in mice by increasing brain bdnf levels. |
2018-06-08 |
2023-08-13 |
mouse |
| Weerawan Boonlert, Hattaya Benya-Aphikul, Jariya Umka Welbat, Ratchanee Rodsir. Ginseng Extract G115 Attenuates Ethanol-Induced Depression in Mice by Increasing Brain BDNF Levels. Nutrients. vol 9. issue 9. 2018-06-08. PMID:28837087. |
the decrease of brain-derived neurotrophic factor (bdnf) has been reported in alcohol use disorder and major depression. |
2018-06-08 |
2023-08-13 |
mouse |
| Yafit Hirshler, Ravid Doro. Neuroplasticity-related mechanisms underlying the antidepressant-like effects of traditional herbal medicines. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 10. 2018-05-30. PMID:28807619. |
brain-derived neurotrophic factor (bdnf) is a biomarker for neuroplasticity-related mechanisms compromised in depression and recovered by conventional antidepressants, including synaptic plasticity, cell survival, neurogenesis and spine formation. |
2018-05-30 |
2023-08-13 |
Not clear |