| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hang Xu, Jiesi Wang, Ke Zhang, Mei Zhao, Bart Ellenbroek, Feng Shao, Weiwen Wan. Effects of adolescent social stress and antidepressant treatment on cognitive inflexibility and Bdnf epigenetic modifications in the mPFC of adult mice. Psychoneuroendocrinology. vol 88. 2018-12-31. PMID:29195162. |
this change was accompanied by a down-regulation of bdnf gene expression in the medial prefrontal cortex (mpfc); this gene encodes a key molecule involved in depression and antidepressant action. |
2018-12-31 |
2023-08-13 |
mouse |
| Hang Xu, Jiesi Wang, Ke Zhang, Mei Zhao, Bart Ellenbroek, Feng Shao, Weiwen Wan. Effects of adolescent social stress and antidepressant treatment on cognitive inflexibility and Bdnf epigenetic modifications in the mPFC of adult mice. Psychoneuroendocrinology. vol 88. 2018-12-31. PMID:29195162. |
these results suggest that epigenetic changes to the bdnf gene in the mpfc after adolescent social adversity may be involved in the regulation of cognitive dysfunction in depression and antidepressant action in adulthood. |
2018-12-31 |
2023-08-13 |
mouse |
| Zhaoxiang Ren, Pengju Yan, Liushuai Zhu, Huicui Yang, Yafei Zhao, Brian P Kirby, John L Waddington, Xuechu Zhe. Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation. Psychopharmacology. vol 235. issue 1. 2018-12-19. PMID:29058041. |
major depressive disorder (mdd) is a highly prevalent illness that affects large populations across the world, and increasing evidence suggests that neuroinflammation and levels of brain-derived neurotrophic factor (bdnf) are closely related to depression. |
2018-12-19 |
2023-08-13 |
Not clear |
| Yizhen Wu, Xu-Feng Huang, Christopher Bell, Yinghua Y. Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice. CNS neuroscience & therapeutics. vol 24. issue 2. 2018-12-11. PMID:29130652. |
obesity impairs leptin-induced regulation of brain-derived neurotrophic factor (bdnf) expression and synaptogenesis, which has been considered to be associated with the incidence of neuronal degenerative diseases, cognitive decline, and depression. |
2018-12-11 |
2023-08-13 |
mouse |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
furthermore, it is thought that bdnf also plays a crucial role in major depression. |
2018-12-11 |
2023-08-13 |
Not clear |
| Tatsuo Fujiwara, Soichi Kono, Kyoko Katakura, Kazumichi Abe, Atsushi Takahashi, Naohiko Gunji, Aki Yokokawa, Kazumasa Kawashima, Rieko Suzuki, Akira Wada, Itaru Miura, Hirooki Yabe, Hiromasa Ohir. Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients. Scientific reports. vol 8. issue 1. 2018-11-20. PMID:29321655. |
center for epidemiologic studies depression scale (ces-d) scores were determined, nirs was performed, and serum bdnf levels were measured in all subjects. |
2018-11-20 |
2023-08-13 |
human |
| Yan-Jiao Li, Yu-Jiao Li, Liu-Di Yang, Kun Zhang, Kai-Yin Zheng, Xin-Miao Wei, Qi Yang, Wen-Min Niu, Ming-Gao Zhao, Yu-Mei W. Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway. Behavioural brain research. vol 348. 2018-11-05. PMID:29680784. |
classic antidepressants benefit depression patients partially by improving neurogenesis and/or brain-derived neurotrophic factor (bdnf)/trkb pathway which were impaired in depression. |
2018-11-05 |
2023-08-13 |
mouse |
| Margaret A French, Susanne M Morton, Ryan T Pohlig, Darcy S Reisma. The relationship between BDNF Val66Met polymorphism and functional mobility in chronic stroke survivors. Topics in stroke rehabilitation. vol 25. issue 4. 2018-11-01. PMID:29480080. |
methods participants 6 months post-stroke completed the fugl-meyer lower extremity assessment (fmle), yesavage geriatric depression scale (ygds), 10 meter walk test (ssws), and bdnf genotype testing. |
2018-11-01 |
2023-08-13 |
human |
| Xue-Qin Chen, Cheng-Fu Li, Shu-Jiao Chen, Wen-Na Liang, Miao Wang, Shuang-Shuang Wang, Shu-Qi Dong, Li-Tao Yi, Can-Dong L. The antidepressant-like effects of Chaihu Shugan San: Dependent on the hippocampal BDNF-TrkB-ERK/Akt signaling activation in perimenopausal depression-like rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-10-31. PMID:29843044. |
considering the high prevalence of perimenopausal depression around the world, the goal of the present study was to determine whether brain-derived neurotrophic factor (bdnf) signaling is required for the antidepressant-like effects of css in perimenopausal depressive-like rats. |
2018-10-31 |
2023-08-13 |
rat |
| Peipei Wang, Cuizhen Zhang, Qinyu Lv, Chenxi Bao, Hong Sun, Guo Ma, Yiru Fang, Zhenghui Yi, Weimin Ca. Association of DNA methylation in BDNF with escitalopram treatment response in depressed Chinese Han patients. European journal of clinical pharmacology. vol 74. issue 8. 2018-10-23. PMID:29748862. |
the neurotrophin brain-derived neurotrophic factor (bdnf) has been found to be associated with both the pathophysiology of depression and antidepressants response. |
2018-10-23 |
2023-08-13 |
Not clear |
| Marco Antonio Caldieraro, Madison McKee, Sandra Leistner-Segal, Edgar Arrua Vares, Francyne Kubaski, Lucas Spanemberg, Ana Carolina Brusius-Facchin, Marcelo P Fleck, David Mischoulo. Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 5. 2018-10-17. PMID:28656803. |
val66met polymorphism association with serum bdnf and inflammatory biomarkers in major depression. |
2018-10-17 |
2023-08-13 |
Not clear |
| Kadri Andre, Olli Kampman, Merja Viikki, Eija Setälä-Soikkeli, Ari Illi, Nina Mononen, Terho Lehtimäki, Esa Leinone. BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. Acta neuropsychiatrica. vol 30. issue 3. 2018-10-05. PMID:29310728. |
bdnf and nrg1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. |
2018-10-05 |
2023-08-13 |
human |
| Kadri Andre, Olli Kampman, Merja Viikki, Eija Setälä-Soikkeli, Ari Illi, Nina Mononen, Terho Lehtimäki, Esa Leinone. BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. Acta neuropsychiatrica. vol 30. issue 3. 2018-10-05. PMID:29310728. |
we investigated the separate effects of and possible interactions between the functional polymorphisms of brain-derived neurotrophic factor (bdnf) rs11030101, bdnf rs61888800, and neuregulin-1 (nrg1) rs3924999 and nrg1 rs6994992 on change of temperament scores in a clinical sample of subjects with major depression (mdd), who received selective serotonin reuptake inhibitor treatment for a period of 6 weeks. |
2018-10-05 |
2023-08-13 |
human |
| Tatyana Vinnik, Michael Kirby, Maryia Bairachnaya, Igor Koman, Tatyana Tarkina, Gulnaz Sadykova, Gulshara Abildinova, Gulnara Batpenova, Albert Pinhaso. Seasonality and BDNF polymorphism influences depression outcome in patients with atopic dermatitis and psoriasis. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 18. issue 8. 2018-09-26. PMID:27409526. |
seasonality and bdnf polymorphism influences depression outcome in patients with atopic dermatitis and psoriasis. |
2018-09-26 |
2023-08-13 |
Not clear |
| Tatyana Vinnik, Michael Kirby, Maryia Bairachnaya, Igor Koman, Tatyana Tarkina, Gulnaz Sadykova, Gulshara Abildinova, Gulnara Batpenova, Albert Pinhaso. Seasonality and BDNF polymorphism influences depression outcome in patients with atopic dermatitis and psoriasis. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 18. issue 8. 2018-09-26. PMID:27409526. |
to examine the effect of seasonality and rs6265 genotype on depression outcome and brain-derived neurotrophic factor (bdnf) level with dermatitis patients from onset through remission. |
2018-09-26 |
2023-08-13 |
Not clear |
| Sung Woo Park, Mi Kyoung Seo, Jung Goo Lee, Le Thi Hien, Young Hoon Ki. Effects of maternal separation and antidepressant drug on epigenetic regulation of the brain-derived neurotrophic factor exon I promoter in the adult rat hippocampus. Psychiatry and clinical neurosciences. vol 72. issue 4. 2018-09-13. PMID:28990703. |
brain-derived neurotrophic factor (bdnf) has been implicated in the pathophysiology of depression and antidepressant drug action. |
2018-09-13 |
2023-08-13 |
rat |
| b' Rukiye \\xc3\\x87olak Sivri, Ayhan Bilgi\\xc3\\xa7, \\xc4\\xb0brahim K\\xc4\\xb1l\\xc4\\xb1n\\xc3\\xa. Cytokine, chemokine and BDNF levels in medication-free pediatric patients with obsessive-compulsive disorder. European child & adolescent psychiatry. vol 27. issue 8. 2018-09-07. PMID:29302747.' |
multivariate analysis of covariance (mancova) revealed a significant main effect on both groups for the levels of serum cytokine, chemokine, and bdnf, an effect that was independent of severities of depression and anxiety [pillai's trace v = 0.371, f (11, 70) = 3.756, p < 0.001, hp |
2018-09-07 |
2023-08-13 |
Not clear |
| Maria Skibinska, Agata Groszewska, Pawel Kapelski, Aleksandra Rajewska-Rager, Joanna Pawlak, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Joanna Twarowska-Hause. Val66Met functional polymorphism and serum protein level of brain-derived neurotrophic factor (BDNF) in acute episode of schizophrenia and depression. Pharmacological reports : PR. vol 70. issue 1. 2018-09-07. PMID:29331787. |
val66met functional polymorphism and serum protein level of brain-derived neurotrophic factor (bdnf) in acute episode of schizophrenia and depression. |
2018-09-07 |
2023-08-13 |
Not clear |
| Maria Skibinska, Agata Groszewska, Pawel Kapelski, Aleksandra Rajewska-Rager, Joanna Pawlak, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Joanna Twarowska-Hause. Val66Met functional polymorphism and serum protein level of brain-derived neurotrophic factor (BDNF) in acute episode of schizophrenia and depression. Pharmacological reports : PR. vol 70. issue 1. 2018-09-07. PMID:29331787. |
bdnf has been implicated in the pathogenesis of schizophrenia and depression. |
2018-09-07 |
2023-08-13 |
Not clear |
| Maria Skibinska, Agata Groszewska, Pawel Kapelski, Aleksandra Rajewska-Rager, Joanna Pawlak, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Joanna Twarowska-Hause. Val66Met functional polymorphism and serum protein level of brain-derived neurotrophic factor (BDNF) in acute episode of schizophrenia and depression. Pharmacological reports : PR. vol 70. issue 1. 2018-09-07. PMID:29331787. |
the aim of this study was to determine the effect of bdnf gene val66met functional polymorphism on serum bdnf concentration in patients with schizophrenia, during depression episode and in healthy control group. |
2018-09-07 |
2023-08-13 |
Not clear |