| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianhua Qin, Qingjun Ma, Dongmei M. Low-dose Sevoflurane Attenuates Cardiopulmonary Bypass (CPB)- induced Postoperative Cognitive Dysfunction (POCD) by Regulating Hippocampus Apoptosis via PI3K/AKT Pathway. Current neurovascular research. vol 17. issue 3. 2021-09-29. PMID:32400333. |
cardiopulmonary bypass (cpb) caused postoperative cognitive dysfunction (pocd) was characterized by hippocampus apoptosis, which seriously limited the therapeutic efficacy and utilization of cpb in clinic. |
2021-09-29 |
2023-08-13 |
Not clear |
| Jianan Wang, Shoufeng Zhu, Wenping Lu, Ao Li, Yuqi Zhou, Yihuan Chen, Ming Chen, Cheng Qian, Xianwen Hu, Ye Zhang, Chunxia Huan. Varenicline improved laparotomy-induced cognitive impairment by restoring mitophagy in aged mice. European journal of pharmacology. 2021-09-28. PMID:34582844. |
after chronic varenicline administration (1 mg/kg/day), cognitive dysfunction, hippocampal oxidative stress, as well as fragile mitophagy were improved. |
2021-09-28 |
2023-08-13 |
mouse |
| Curtis Wells Dewey, Mark Rishniw, Philippa J Johnson, Simon Platt, Kelsey Robinson, Joseph Sackman, Marissa O'Donnel. Canine cognitive dysfunction patients have reduced total hippocampal volume compared with aging control dogs: A comparative magnetic resonance imaging study. Open veterinary journal. vol 10. issue 4. 2021-09-27. PMID:33614439. |
canine cognitive dysfunction patients have reduced total hippocampal volume compared with aging control dogs: a comparative magnetic resonance imaging study. |
2021-09-27 |
2023-08-13 |
human |
| Curtis Wells Dewey, Mark Rishniw, Philippa J Johnson, Simon Platt, Kelsey Robinson, Joseph Sackman, Marissa O'Donnel. Canine cognitive dysfunction patients have reduced total hippocampal volume compared with aging control dogs: A comparative magnetic resonance imaging study. Open veterinary journal. vol 10. issue 4. 2021-09-27. PMID:33614439. |
hippocampal atrophy has not been documented via mri in canine cognitive dysfunction (ccd), which is considered as the dog model of human ad. |
2021-09-27 |
2023-08-13 |
human |
| Wenli Yu, Jingshu Lyu, Lili Jia, Mingwei Sheng, Hongli Yu, Hongyin D. Corrigendum to "Dexmedetomidine Ameliorates Hippocampus Injury and Cognitive Dysfunction Induced by Hepatic Ischemia/Reperfusion by Activating SIRT3-Mediated Mitophagy and Inhibiting Activation of the NLRP3 Inflammasome in Young Rats". Oxidative medicine and cellular longevity. vol 2021. 2021-09-27. PMID:34398166. |
corrigendum to "dexmedetomidine ameliorates hippocampus injury and cognitive dysfunction induced by hepatic ischemia/reperfusion by activating sirt3-mediated mitophagy and inhibiting activation of the nlrp3 inflammasome in young rats". |
2021-09-27 |
2023-08-13 |
rat |
| Wenli Yu, Jingshu Lyu, Lili Jia, Mingwei Sheng, Hongli Yu, Hongyin D. Dexmedetomidine Ameliorates Hippocampus Injury and Cognitive Dysfunction Induced by Hepatic Ischemia/Reperfusion by Activating SIRT3-Mediated Mitophagy and Inhibiting Activation of the NLRP3 Inflammasome in Young Rats. Oxidative medicine and cellular longevity. vol 2020. 2021-09-27. PMID:34493950. |
dexmedetomidine ameliorates hippocampus injury and cognitive dysfunction induced by hepatic ischemia/reperfusion by activating sirt3-mediated mitophagy and inhibiting activation of the nlrp3 inflammasome in young rats. |
2021-09-27 |
2023-08-13 |
rat |
| Chu-Wen Feng, Yuan-Yuan Qu, Zhong-Ren Sun, Yu-Lin Wang, Peng Zhang, Qing-Yong Wang, Wan-Juan Lin, Lin Zhang, Tian-Song Yan. [Electroacupuncture improves cognitive function by inhibiting NF-κB activity in rats with chronic fatigue syndrome]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 9. 2021-09-27. PMID:34558244. |
to observe the effect of electroacupuncture (ea) on the expression of nf-κb p65 in hippocampus and the morphology of hippocampus in rats with chronic fatigue syndrome (cfs), so as to explore its mechanism in improving cognitive dysfunction of cfs. |
2021-09-27 |
2023-08-13 |
rat |
| Di Wu, Jay Prakash P Kumal, Xiaodi Lu, Yixuan Li, Dongsheng Mao, Xudong Tang, Meitong Nie, Xin Liu, Liang Sun, Bin Liu, Yafang Zhan. Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model. Frontiers in neurology. vol 12. 2021-09-21. PMID:34539542. |
traumatic brain injury accelerates the onset of cognitive dysfunction and aggravates alzheimer's-like pathology in the hippocampus by altering the phenotype of microglia in the app/ps1 mouse model. |
2021-09-21 |
2023-08-13 |
mouse |
| Priscilla Bluemel, Jonathan Wickel, Benedikt Grünewald, Mihai Ceanga, Silke Keiner, Otto W Witte, Christoph Redecker, Christian Geis, Albrecht Kunz. Sepsis promotes gliogenesis and depletes the pool of radial glia like stem cells in the hippocampus. Experimental neurology. vol 338. 2021-09-17. PMID:33387461. |
here, we hypothesized that endogenous neural stems cells and adult neurogenesis in the hippocampus are impaired following sepsis and that these changes may contribute to persistent cognitive dysfunction when the animals have physically fully recovered. |
2021-09-17 |
2023-08-13 |
Not clear |
| Lei Huang, Yang Zhang, Yongwei Wang, Yajia La. Relationship Between Chronic Noise Exposure, Cognitive Impairment, and Degenerative Dementia: Update on the Experimental and Epidemiological Evidence and Prospects for Further Research. Journal of Alzheimer's disease : JAD. vol 79. issue 4. 2021-09-15. PMID:33459723. |
experimental studies have indicated that long-term exposure to noise might accelerate cognitive dysfunction, amyloid-β deposition, and tau hyperphosphorylation in different brain regions such as the hippocampus and cortex. |
2021-09-15 |
2023-08-13 |
Not clear |
| Guanghong Sui, Caixia Yang, Lu Wang, Xiangyang Xiong, Mengtian Guo, Zheng Chen, Feng Wan. Exogenous IGF-1 improves tau pathology and neuronal pyroptosis in high-fat diet mice with cognitive dysfunction. Metabolic brain disease. vol 36. issue 7. 2021-09-14. PMID:34269982. |
during in vitro experiment, high-fat diet mice showed cognitive dysfunction, significant hyperphosphorylation of tau protein and neuronal pyroptosis in hippocampus compared with the sham mice. |
2021-09-14 |
2023-08-13 |
mouse |
| Liangyu Peng, Xin Fang, Fangxia Xu, Shuai Liu, Yue Qian, Xiangdan Gong, Xin Zhao, Zhengliang Ma, Tianjiao Xia, Xiaoping G. Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice. Frontiers in aging neuroscience. vol 13. 2021-09-14. PMID:34512303. |
metformin pretreatment strongly ameliorated hippocampal ir and cognitive dysfunction caused by isoflurane in wt mice, but was less effective in t2dm mice. |
2021-09-14 |
2023-08-13 |
mouse |
| Liangyu Peng, Xin Fang, Fangxia Xu, Shuai Liu, Yue Qian, Xiangdan Gong, Xin Zhao, Zhengliang Ma, Tianjiao Xia, Xiaoping G. Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice. Frontiers in aging neuroscience. vol 13. 2021-09-14. PMID:34512303. |
our findings show hippocampal ir and tau hyperphosphorylation contribute to acute isoflurane-induced cognitive dysfunction. |
2021-09-14 |
2023-08-13 |
mouse |
| Xiaoyue Qiao, Hailin Wang, Li Lu, Jinglei Chen, Qinpei Cheng, Meng Guo, Yayi Hou, Huan Do. Hippocampal microglia CD40 mediates NPSLE cognitive dysfunction in mice. Journal of neuroimmunology. vol 357. 2021-09-13. PMID:34062352. |
hippocampal microglia cd40 mediates npsle cognitive dysfunction in mice. |
2021-09-13 |
2023-08-13 |
mouse |
| Alba Puente-Bedia, María T Berciano, Olga Tapia, Carmen Martínez-Cué, Miguel Lafarga, Noemí Rued. Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies. International journal of molecular sciences. vol 22. issue 3. 2021-09-08. PMID:33514010. |
these nuclear alterations could play an important role in the neuromorphological and/or functional alterations of the hippocampal gcs implicated in the cognitive dysfunction characteristic of ts mice. |
2021-09-08 |
2023-08-13 |
mouse |
| Juan He, Zhuo Chen, Xuan Kang, Lin Wu, Jia-Mei Jiang, Su-Mei Liu, Hai-Jun Wei, Yong-Jun Chen, Wei Zou, Chun-Yan Wang, Ping Zhan. SIRT1 Mediates H Neurochemical research. vol 46. issue 3. 2021-09-07. PMID:33534060. |
sirt1 mediates h diabetes-associated cognitive dysfunction (dacd) characterized by hippocampal injury increases the risk of major cerebrovascular events and death. |
2021-09-07 |
2023-08-13 |
Not clear |
| Sinan Saral, Atilla Topçu, Mehmet Alkanat, Tolga Mercantepe, Kerimali Akyıldız, Lamiye Yıldız, Levent Tümkaya, Zihni Açar Yazıcı, Adnan Yılma. Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction. Behavioural brain research. vol 408. 2021-09-02. PMID:33845103. |
apelin-13 activates the hippocampal bdnf/trkb signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction. |
2021-09-02 |
2023-08-13 |
rat |
| Hui Yang, Lin Tang, Zhan Qu, Shi-Hui Lei, Wei Li, Yu-Hong Wan. Hippocampal insulin resistance and the Sirtuin 1 signaling pathway in diabetes-induced cognitive dysfunction. Neural regeneration research. vol 16. issue 12. 2021-08-26. PMID:33907035. |
hippocampal insulin resistance and the sirtuin 1 signaling pathway in diabetes-induced cognitive dysfunction. |
2021-08-26 |
2023-08-13 |
rat |
| Jing Sun, Xiang Zhou, Jusheng Wu, Renjie Xiao, Yong Chen, Yimei Lu, Haili Lan. Ligustilide enhances hippocampal neural stem cells activation to restore cognitive function in the context of postoperative cognitive dysfunction. The European journal of neuroscience. vol 54. issue 3. 2021-08-20. PMID:34192824. |
ligustilide enhances hippocampal neural stem cells activation to restore cognitive function in the context of postoperative cognitive dysfunction. |
2021-08-20 |
2023-08-13 |
mouse |
| Jing Sun, Xiang Zhou, Jusheng Wu, Renjie Xiao, Yong Chen, Yimei Lu, Haili Lan. Ligustilide enhances hippocampal neural stem cells activation to restore cognitive function in the context of postoperative cognitive dysfunction. The European journal of neuroscience. vol 54. issue 3. 2021-08-20. PMID:34192824. |
however, the function and mechanisms of lig-mediated hippocampal neural stem cells (h-nscs) activation as well as cognitive recovery in the context of post-operative cognitive dysfunction (pocd) remain elusive and need to be explored. |
2021-08-20 |
2023-08-13 |
mouse |