| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Wang, A-Ni Zheng, Huan Yang, Qiang Wang, Biao Dai, Jia-Ju Wang, Yi-Tong Wan, Zhi-Bin Liu, Si-Yang Li. Olfactory Three-Needle Electroacupuncture Improved Synaptic Plasticity and Gut Microbiota of SAMP8 Mice by Stimulating Olfactory Nerve. Chinese journal of integrative medicine. 2023-11-24. PMID:37999886. |
to investigate the effects and mechanisms of olfactory three-needle (otn) electroacupuncture (ea) stimulation of the olfactory system on cognitive dysfunction, synaptic plasticity, and the gut microbiota in senescence-accelerated mouse prone 8 (samp8) mice. |
2023-11-24 |
2023-11-29 |
mouse |
| Yansong Li, Tao Jiang, Mengyu Du, Shuxuan He, Ning Huang, Bo Cheng, Chaoying Yan, Wenxin Tang, Wei Gao, Hongyan Guo, Qiao Li, Qiang Wan. Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction. Experimental & molecular medicine. 2023-11-01. PMID:37907746. |
inhibiting fructose metabolism via ketohexokinase depletion reduces microglial activation, leading to the restoration of mitochondrial homeostasis, recovery of structural synaptic plasticity, improvement of ca1 pyramidal neuron electrophysiology and alleviation of cognitive dysfunction. |
2023-11-01 |
2023-11-08 |
mouse |
| Qiong Xiang, Jia-Sheng Tao, Shuai Dong, Xiao-Lin Liu, Liang Yang, Li-Ni Liu, Jing Deng, Xian-Hui L. Heterogeneity and synaptic plasticity analysis of hippocampus based on db Psychoneuroendocrinology. vol 159. 2023-10-28. PMID:37898037. |
heterogeneity and synaptic plasticity analysis of hippocampus based on db chronic hyperglycemia can cause changes in synaptic plasticity of hippocampal cells, which has accelerated the pathological process of cognitive dysfunction. |
2023-10-28 |
2023-11-08 |
Not clear |
| Yanping Liu, Qiang Liu, Haibi Wang, Yongkang Qiu, Jiatao Lin, Weifeng Wu, Ning Wang, Wei Dong, Jie Wan, Chen Chen, Shuai Li, Hui Zheng, Yuqing W. Hippocampal synaptic plasticity injury mediated by SIRT1 downregulation is involved in chronic pain-related cognitive dysfunction. CNS neuroscience & therapeutics. 2023-08-18. PMID:37592394. |
hippocampal synaptic plasticity injury mediated by sirt1 downregulation is involved in chronic pain-related cognitive dysfunction. |
2023-08-18 |
2023-09-07 |
Not clear |
| Yanping Liu, Qiang Liu, Haibi Wang, Yongkang Qiu, Jiatao Lin, Weifeng Wu, Ning Wang, Wei Dong, Jie Wan, Chen Chen, Shuai Li, Hui Zheng, Yuqing W. Hippocampal synaptic plasticity injury mediated by SIRT1 downregulation is involved in chronic pain-related cognitive dysfunction. CNS neuroscience & therapeutics. 2023-08-18. PMID:37592394. |
cognitive dysfunction associated with chronic pain may be caused by impaired synaptic plasticity. |
2023-08-18 |
2023-09-07 |
Not clear |
| Andrea Flores, Paula Moyano, Emma Sola, José Manuel García, Jimena García, María Teresa Frejo, Lucia Guerra-Menéndez, Elena Labajo, Inés Lobo, Luisa Abascal, Javier Del Pin. Bisphenol-A Neurotoxic Effects on Basal Forebrain Cholinergic Neurons In Vitro and In Vivo. Biology. vol 12. issue 6. 2023-06-28. PMID:37372067. |
these results may help to explain the synaptic plasticity, cognitive dysfunction, and neurodegeneration induced by the plasticizer bpa, which could contribute to their prevention. |
2023-06-28 |
2023-08-14 |
rat |
| Shamprasad Varija Raghu, Avinash Kundadka Kudva, Rajanikant Golgodu Krishnamurthy, Jayesh Mudgal, Thomas George, Manjeshwar Shrinath Balig. Neuroprotective effects of dietary plants and phytochemicals against radiation-induced cognitive and behavioral deficits: a comprehensive review of evidence and prospects for future research. Food & function. 2023-06-23. PMID:37350117. |
exposure to an unsafe dose of radiation can cause increased permeability of the blood-brain barrier (bbb), neuronal apoptosis, reduced neurogenesis, impaired synaptic plasticity, and cognitive dysfunction. |
2023-06-23 |
2023-08-14 |
Not clear |
| Dan-Dan Wu, Jie Cheng, Ya-Ni Zheng, Yu-Tong Liu, Shuang-Xin Hou, Li-Fen Liu, Liang Huang, Qiong-Lan Yua. Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer's disease mouse model. Frontiers in cellular neuroscience. vol 17. 2023-05-22. PMID:37213217. |
as synaptic glycoprotein neuroplastin 65 (np65) is related with synaptic plasticity and complex molecular events underlying learning and memory, we hypothesized that np65 would be involved in cognitive dysfunction and aβ plaque formation of ad. |
2023-05-22 |
2023-08-14 |
mouse |
| Lei Ye, Shu Shu, Junqiu Jia, Min Sun, Siyi Xu, Xinyu Bao, Huijie Bian, Yi Liu, Meijuan Zhang, Xiaolei Zhu, Feng Bai, Yun X. Absent in melanoma 2 mediates aging-related cognitive dysfunction by acting on complement-dependent microglial phagocytosis. Aging cell. 2023-05-13. PMID:37177836. |
these results suggest a critical role for aim2 in regulating synaptic plasticity and ps function and provide a new direction for ameliorating aging-associated cognitive dysfunction. |
2023-05-13 |
2023-08-14 |
mouse |
| Luyu Hu, Qiaoyu Gong, Yanjie Zhou, Yajuan Wang, Tao Qiu, Yuting Fang, Wanbin Huang, Jingjing Liang, Zheman Xia. Arc-Mediated Synaptic Plasticity Regulates Cognitive Function in a Migraine Mouse Model. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831874. |
the present results suggest that arc-mediated synaptic plasticity may be an essential mechanism of cognitive dysfunction in migraine. |
2023-02-25 |
2023-08-14 |
mouse |
| Agnieszka Wnuk, Karolina Przepiórska, Bernadeta Angelika Pietrzak, Małgorzata Kajt. Emerging Evidence on Membrane Estrogen Receptors as Novel Therapeutic Targets for Central Nervous System Pathologies. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835454. |
according to available data, non-gper-dependent mers elicit protective effects against brain damage, synaptic plasticity impairment, memory and cognitive dysfunctions, metabolic imbalance, and vascular insufficiency. |
2023-02-25 |
2023-08-14 |
human |
| Ying Zhang, Qian Zhou, Lu Lu, Yu Su, Wei Shi, Hu Zhang, Ran Liu, Yuepu Pu, Lihong Yi. Copper Induces Cognitive Impairment in Mice via Modulation of Cuproptosis and CREB Signaling. Nutrients. vol 15. issue 4. 2023-02-25. PMID:36839332. |
in conclusion, cu might mediate cuproptosis, damage synaptic plasticity and inhibit the creb/bdnf pathway to cause cognitive dysfunction in mice. |
2023-02-25 |
2023-08-14 |
mouse |
| Na Fu, Jie Yu, Lin Zhu, Lilin Yang, Lina Ma, Jie He, Huawen Yu, Jinqing Liu, Yu Tian, Jie X. Role of miR-219a-5p in regulating NMDAR in nonylphenol-induced synaptic plasticity damage. Ecotoxicology and environmental safety. vol 252. 2023-02-03. PMID:36736231. |
this study aimed to clarify whether np exposure could lead to cognitive dysfunction and synaptic plasticity impairment, and also explore the mechanism of microrna (mir)- 219a-5p regulation of n-methyl-d-aspartate receptor (nmdar) in np-induced synaptic plasticity impairment in vivo and in vitro. |
2023-02-03 |
2023-08-14 |
rat |
| Neha Keshri, Hanumanthappa Nandeesh. Dysregulation of Synaptic Plasticity Markers in Schizophrenia. Indian journal of clinical biochemistry : IJCB. vol 38. issue 1. 2023-01-23. PMID:36684500. |
we conclude that markers of synaptic plasticity are altered in schizophrenia and may lead to complications of schizophrenia including cognitive dysfunction. |
2023-01-23 |
2023-08-14 |
Not clear |
| Huiya Ying, Zilong Zhang, Wei Wang, Zijing Yang, Cancan You, Yuanai Li, Xiaohong Cai, Xiucui L. Inhibition of Calcium-Sensing Receptor Alleviates Chronic Intermittent Hypoxia-Induced Cognitive Dysfunction via CaSR-PKC-ERK1/2 Pathway. Molecular neurobiology. 2023-01-04. PMID:36600080. |
overall, our findings revealed that casr held a critical function on cih-induced cognitive dysfunction in mice by accelerating hippocampal neuronal apoptosis and reducing synaptic plasticity via augmenting casr-pkc-erk1/2 pathway; otherwise, inhibition of casr alleviated cih-induced cognitive dysfunction. |
2023-01-04 |
2023-08-14 |
mouse |
| Xupeng Wang, Yanan Li, Juan Zhao, Jiaxu Yu, Qi Zhang, Fang Xu, Yahui Zhang, Qi Zhou, Chunping Yin, Zhiyong Hou, Qiujun Wan. Activation of astrocyte Gq pathway in hippocampal CA1 region attenuates anesthesia/surgery induced cognitive dysfunction in aged mice. Frontiers in aging neuroscience. vol 14. 2022-11-28. PMID:36437995. |
we used golgi staining and neuroelectrophysiological techniques to detect structurally and functionally impaired synaptic plasticity in hippocampal ca1 region of postoperative cognitive dysfunction aged mice, respectively. |
2022-11-28 |
2023-08-14 |
mouse |
| Xupeng Wang, Yanan Li, Juan Zhao, Jiaxu Yu, Qi Zhang, Fang Xu, Yahui Zhang, Qi Zhou, Chunping Yin, Zhiyong Hou, Qiujun Wan. Activation of astrocyte Gq pathway in hippocampal CA1 region attenuates anesthesia/surgery induced cognitive dysfunction in aged mice. Frontiers in aging neuroscience. vol 14. 2022-11-28. PMID:36437995. |
the results of novel object recognition and conditioned fear experiments showed that cno activation of astrocyte gq pathway could improve the learning and memory ability and the synaptic plasticity of postoperative cognitive dysfunction aged mice was also improved. |
2022-11-28 |
2023-08-14 |
mouse |
| Xiaoxuan Yang, Chen Chen, Dongmei Qu, Yanping Liu, Ning Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Han L. Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice. Frontiers in aging neuroscience. vol 14. 2022-11-25. PMID:36425318. |
aberrant expression of fbxo22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice. |
2022-11-25 |
2023-08-14 |
mouse |
| Xiaoxuan Yang, Chen Chen, Dongmei Qu, Yanping Liu, Ning Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Han L. Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice. Frontiers in aging neuroscience. vol 14. 2022-11-25. PMID:36425318. |
our results showed that fbxo22 is involved in the regulation of repeated propofol treatment induced changes of synaptic plasticity and cognitive dysfunction in adult mice. |
2022-11-25 |
2023-08-14 |
mouse |
| Xuying Li, Qian Zhai, Xingchun Gou, Minxue Quan, Yansong Li, Xiaohua Zhang, Bin Deng, Yi Tian, Qiang Wang, Lichao Ho. Involvement of Paired Immunoglobulin-Like Receptor B in Cognitive Dysfunction Through Hippocampal-Dependent Synaptic Plasticity Impairments in Mice Subjected to Chronic Sleep Restriction. Molecular neurobiology. 2022-11-23. PMID:36417104. |
involvement of paired immunoglobulin-like receptor b in cognitive dysfunction through hippocampal-dependent synaptic plasticity impairments in mice subjected to chronic sleep restriction. |
2022-11-23 |
2023-08-14 |
mouse |