| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ken Koda, Yukio Ago, Yana Cong, Yuki Kita, Kazuhiro Takuma, Toshio Matsud. Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice. Journal of neurochemistry. vol 114. issue 1. 2010-07-19. PMID:20403082. |
this study examined the effects of acute and chronic administration of adhd drugs on the extracellular levels of noradrenaline (na), dopamine (da) and serotonin (5-ht), and the expression of the neuronal activity marker c-fos in the prefrontal cortex and striatum of mice. |
2010-07-19 |
2023-08-12 |
mouse |
| Ken Koda, Yukio Ago, Yana Cong, Yuki Kita, Kazuhiro Takuma, Toshio Matsud. Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice. Journal of neurochemistry. vol 114. issue 1. 2010-07-19. PMID:20403082. |
acute adhd drugs increased na and da, but not 5-ht, levels in the prefrontal cortex of mice. |
2010-07-19 |
2023-08-12 |
mouse |
| Brendan E Depue, Gregory C Burgess, Erik G Willcutt, L Cinnamon Bidwell, Luka Ruzic, Marie T Banic. Symptom-correlated brain regions in young adults with combined-type ADHD: their organization, variability, and relation to behavioral performance. Psychiatry research. vol 182. issue 2. 2010-07-01. PMID:20399622. |
the results implicated a broad array of brain regions that are linked to behaviors compromised in adhd, including executive function/cognitive control (prefrontal cortex, dorsal striatum), reward and motivational circuitry (ventral striatum), and stimulus representation and timing (posterior cortex and cerebellum). |
2010-07-01 |
2023-08-12 |
Not clear |
| Jie Qiu, Qin Hong, Rong-hua Chen, Mei-ling Tong, Min Zhang, Li Fei, Xiao-qin Pan, Mei Guo, Xi-rong Guo, Xia Ch. Gene expression profiles in the prefrontal cortex of SHR rats by cDNA microarrays. Molecular biology reports. vol 37. issue 4. 2010-06-08. PMID:19572212. |
we have undertaken cdna microarrays to identify differentially expressed genes in the prefrontal cortex (pfc) of spontaneously hypertensive-rat (shr), a rodent model of attention deficit hyperactivity disorder (adhd) versus control wistar-kyoto (wky) rats. |
2010-06-08 |
2023-08-12 |
rat |
| Hideki Negoro, Masayuki Sawada, Junzo Iida, Toyosaku Ota, Shohei Tanaka, Toshifumi Kishimot. Prefrontal dysfunction in attention-deficit/hyperactivity disorder as measured by near-infrared spectroscopy. Child psychiatry and human development. vol 41. issue 2. 2010-05-05. PMID:19826946. |
during the stroop color-word task, the oxy-hb changes in the control group were significantly larger than that in the adhd group in the inferior prefrontal cortex, especially in the inferior lateral prefrontal cortex bilaterally. |
2010-05-05 |
2023-08-12 |
human |
| Alessandra M Passarotti, John A Sweeney, Mani N Pavulur. Neural correlates of response inhibition in pediatric bipolar disorder and attention deficit hyperactivity disorder. Psychiatry research. vol 181. issue 1. 2010-04-20. PMID:19926457. |
fmri findings showed that for trials requiring response inhibition, the adhd group, relative to the pbd and hc groups, demonstrated reduced activation in both ventrolateral (vlpfc) and dorsolateral (dlpfc) prefrontal cortex, and increased bilateral caudate activation compared with hc. |
2010-04-20 |
2023-08-12 |
Not clear |
| S J Wanchoo, M J Lee, A C Swann, N Dafn. Bilateral six-hydroxydopamine administration to PFC prevents the expression of behavioral sensitization to methylphenidate. Brain research. vol 1312. 2010-03-25. PMID:19932692. |
neuropsychological analyses indicate that adhd patients are impaired on tasks of behavioral inhibition, reward reversal, and working memory, which are functions of the prefrontal cortex (pfc) and are modulated by the mesocortical dopamine (da) system. |
2010-03-25 |
2023-08-12 |
rat |
| Qin Hong, Min Zhang, Xiao-qin Pan, Mei Guo, Fei Li, Mei-ling Tong, Rong-hua Chen, Xi-rong Guo, Xia Ch. Prefrontal cortex Homer expression in an animal model of attention-deficit/hyperactivity disorder. Journal of the neurological sciences. vol 287. issue 1-2. 2010-02-12. PMID:19709672. |
attention-deficit/hyperactivity disorder (adhd) is a pervasive neurobehavioral disorder affecting approximately 5% of children and adolescents and 3% of adults, and the prefrontal cortex (pfc) may play the most critical role in the expression of adhd. |
2010-02-12 |
2023-08-12 |
Not clear |
| A Tang, S J Wanchoo, A C Swann, N Dafn. Psychostimulant treatment for ADHD is modulated by prefrontal cortex manipulation. Brain research bulletin. vol 80. issue 6. 2010-01-20. PMID:19729055. |
psychostimulant treatment for adhd is modulated by prefrontal cortex manipulation. |
2010-01-20 |
2023-08-12 |
rat |
| Amy F T Arnste. Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS drugs. vol 23 Suppl 1. 2009-10-30. PMID:19621976. |
pharmacological studies in animals indicate catecholamine actions in the pfc are highly relevant to adhd. |
2009-10-30 |
2023-08-12 |
Not clear |
| Amy F T Arnste. Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS drugs. vol 23 Suppl 1. 2009-10-30. PMID:19621976. |
blocking na alpha(2a)-receptors in the pfc with yohimbine produces a profile similar to adhd: locomotor hyperactivity, impulsivity and poor working memory. |
2009-10-30 |
2023-08-12 |
Not clear |
| Robert C Wolf, Michael M Plichta, Fabio Sambataro, Andreas J Fallgatter, Christian Jacob, Klaus-Peter Lesch, Martin J Herrmann, Carlos Schönfeldt-Lecuona, Bernhard J Connemann, Georg Grön, Nenad Vasi. Regional brain activation changes and abnormal functional connectivity of the ventrolateral prefrontal cortex during working memory processing in adults with attention-deficit/hyperactivity disorder. Human brain mapping. vol 30. issue 7. 2009-09-03. PMID:19107748. |
previous studies on working memory (wm) function in adults with attention-deficit/hyperactivity disorder (adhd) suggested aberrant activation of the prefrontal cortex and the cerebellum. |
2009-09-03 |
2023-08-12 |
human |
| Robert C Wolf, Michael M Plichta, Fabio Sambataro, Andreas J Fallgatter, Christian Jacob, Klaus-Peter Lesch, Martin J Herrmann, Carlos Schönfeldt-Lecuona, Bernhard J Connemann, Georg Grön, Nenad Vasi. Regional brain activation changes and abnormal functional connectivity of the ventrolateral prefrontal cortex during working memory processing in adults with attention-deficit/hyperactivity disorder. Human brain mapping. vol 30. issue 7. 2009-09-03. PMID:19107748. |
during the delay period of the activation task, however, adhd patients showed significantly less activation in the left ventrolateral prefrontal cortex (vlpfc), as well as in cerebellar and occipital regions compared with healthy control subjects. |
2009-09-03 |
2023-08-12 |
human |
| Catherine Fassbender, Hao Zhang, Wendy M Buzy, Carlos R Cortes, Danielle Mizuiri, Laurel Beckett, Julie B Schweitze. A lack of default network suppression is linked to increased distractibility in ADHD. Brain research. vol 1273. 2009-08-14. PMID:19281801. |
neural measures showed that although both groups displayed a pattern of increasing deactivation of the medial prefrontal cortex (pfc) with increasing task difficulty, the adhd group was significantly less deactive than controls. |
2009-08-14 |
2023-08-12 |
human |
| Doug Hyun Han, Young Sik Lee, Churl Na, Jee Young Ahn, Un Sun Chung, Melissa A Daniels, Charlotte A Haws, Perry F Rensha. The effect of methylphenidate on Internet video game play in children with attention-deficit/hyperactivity disorder. Comprehensive psychiatry. vol 50. issue 3. 2009-08-14. PMID:19374970. |
a number of studies about attention-deficit/hyperactivity disorder (adhd) and internet video game play have examined the prefrontal cortex and dopaminergic system. |
2009-08-14 |
2023-08-12 |
human |
| Pedro E M S Ferreira, André Palmini, Claiton H D Bau, Eugenio Horacio Grevet, João Rubião Hoefel, Luis Augusto Rohde, Maurício Anés, Eloisa Elena Ferreira, Paulo Belmonte-de-Abre. Differentiating attention-deficit/hyperactivity disorder inattentive and combined types: a (1)H-magnetic resonance spectroscopy study of fronto-striato-thalamic regions. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 5. 2009-08-14. PMID:19399368. |
we assessed the (1)h-magnetic resonance spectroscopy profile in ventromedial prefrontal cortex (vmpfc)-thalamic-striatal regions bilaterally in three groups of subjects (age range 18-24 years old): adhd inattentive type (adhd-i; n = 9), adhd combined type (adhd-c; n = 10) and non-adhd controls (n = 12). |
2009-08-14 |
2023-08-12 |
human |
| Paolo Curatolo, Claudio Paloscia, Elisa D'Agati, Romina Moavero, Augusto Pasin. The neurobiology of attention deficit/hyperactivity disorder. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 13. issue 4. 2009-08-12. PMID:18644740. |
adhd involves hypofunction of catecholaminergic circuits, particularly those that project to the prefrontal cortex. |
2009-08-12 |
2023-08-12 |
Not clear |
| Nikos Makris, Joseph Biederman, Michael C Monuteaux, Larry J Seidma. Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorder. Developmental neuroscience. vol 31. issue 1-2. 2009-06-16. PMID:19372685. |
convergent data from neuroimaging, neuropsychological, genetic and neurochemical studies in attention-deficit/hyperactivity disorder (adhd) have implicated dysfunction of the dorsolateral prefrontal cortex (dlpfc) and dorsal anterior cingulate cortex (dacc), which form the cortical arm of the frontostriatal network supporting executive functions. |
2009-06-16 |
2023-08-12 |
Not clear |
| H Halleland, A J Lundervold, A Halmøy, J Haavik, S Johansso. Association between catechol O-methyltransferase (COMT) haplotypes and severity of hyperactivity symptoms in adults. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 3. 2009-05-19. PMID:18802928. |
it has been suggested that symptoms of attention-deficit/hyperactivity disorder (adhd) is related to low dopamine levels in the prefrontal cortex. |
2009-05-19 |
2023-08-12 |
human |
| Eunice Y Yuen, Zhen Ya. Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 2. 2009-04-08. PMID:19144855. |
the dopamine d(4) receptor, which is strongly linked to neuropsychiatric disorders, such as attention deficit-hyperactivity disorder (adhd) and schizophrenia, is highly expressed in pfc gabaergic interneurons, while the physiological role of d(4) in these interneurons is largely unknown. |
2009-04-08 |
2023-08-12 |
Not clear |