| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter Weber, Jürg Lütschg, Hubert Fahnenstic. Cerebral hemodynamic changes in response to an executive function task in children with attention-deficit hyperactivity disorder measured by near-infrared spectroscopy. Journal of developmental and behavioral pediatrics : JDBP. vol 26. issue 2. 2005-12-12. PMID:15827461. |
overall, the normal controls showed lateralized oxygen consumption in the left prefrontal cortex during an extended-attention task, whereas the boys with adhd showed an imbalance between oxygenated and deoxygenated hemoglobin during the short- and extended-attention tasks. |
2005-12-12 |
2023-08-12 |
Not clear |
| S Durston, J A Fossella, B J Casey, H E Hulshoff Pol, A Galvan, H G Schnack, M P Steenhuis, R B Minderaa, J K Buitelaar, R S Kahn, H van Engelan. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Molecular psychiatry. vol 10. issue 7. 2005-12-07. PMID:15724142. |
we show that the dat1 gene, a gene expressed predominantly in the basal ganglia, preferentially influences caudate volume, whereas the drd4 gene, a gene expressed predominantly in the prefrontal cortex, preferentially influences prefrontal gray matter volume in a sample of subjects including subjects with adhd, their unaffected siblings, and healthy controls. |
2005-12-07 |
2023-08-12 |
human |
| Kurt P Schulz, Cheuk Y Tang, Jin Fan, David J Marks, Jeffrey H Newcorn, Angeles M Cheung, Jeffrey M Halperi. Differential prefrontal cortex activation during inhibitory control in adolescents with and without childhood attention-deficit/hyperactivity disorder. Neuropsychology. vol 19. issue 3. 2005-08-09. PMID:15910125. |
however, the adhd group demonstrated significantly greater activation of the left ventrolateral prefrontal cortex during interference control as well as greater activation of the left anterior cingulate cortex, right ventrolateral prefrontal cortex, and left basal ganglia during the dual task of interference control and response competition. |
2005-08-09 |
2023-08-12 |
human |
| Larry J Seidman, Eve M Valera, Nikos Makri. Structural brain imaging of attention-deficit/hyperactivity disorder. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15949998. |
the most replicated alterations in adhd in childhood include significantly smaller volumes in the dorsolateral prefrontal cortex, caudate, pallidum, corpus callosum, and cerebellum. |
2005-07-29 |
2023-08-12 |
human |
| George Bush, Eve M Valera, Larry J Seidma. Functional neuroimaging of attention-deficit/hyperactivity disorder: a review and suggested future directions. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15949999. |
convergent data from neuroimaging, neuropsychological, genetics, and neurochemical studies have implicated dysfunction of fronto-striatal structures (lateral prefrontal cortex, dorsal anterior cingulate cortex, caudate, and putamen) as likely contributing to the pathophysiology of adhd. |
2005-07-29 |
2023-08-12 |
Not clear |
| Adam R Aron, Russell A Poldrac. The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15950000. |
we show that response inhibition--operationalized by go/nogo or stop-signal tasks--requires the prefrontal cortex (pfc), in particular the right inferior frontal cortex (ifc); that patients with adhd have significant response inhibition deficits and show altered functional activation and gray matter volumes in right ifc; and that a number of studies indicate that response inhibition performance is heritable. |
2005-07-29 |
2023-08-12 |
Not clear |
| Vivienne A Russell, Terje Sagvolden, Espen Borgå Johanse. Animal models of attention-deficit hyperactivity disorder. Behavioral and brain functions : BBF. vol 1. 2005-07-29. PMID:16022733. |
aspects of adhd behaviour may result from an imbalance between increased noradrenergic and decreased dopaminergic regulation of neural circuits that involve the prefrontal cortex. |
2005-07-29 |
2023-08-12 |
human |
| b' Birim G\\xc3\\xbcnay Kili\\xc3\\xa. [Neuropsychology of attention deficit hyperactivity disorder: relevant theories and empirical studies]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 16. issue 2. 2005-07-25. PMID:15981150.' |
based on clinical and neuropsychological data it has been stated that both the orbitofrontal cortex and dorsolateral prefrontal cortex are functionally disturbed in adhd. |
2005-07-25 |
2023-08-12 |
human |
| Ozgür Oner, Pinar Oner, Ayla Aysev, Ozlem Küçük, Erkan Ibi. Regional cerebral blood flow in children with ADHD: changes with age. Brain & development. vol 27. issue 4. 2005-06-28. PMID:15862191. |
the results indicated that the left hemisphere dominance in the prefrontal cortex significantly increases with age in adhd cases. |
2005-06-28 |
2023-08-12 |
human |
| Karen Müller Smith, Lorri Bauer, Mariellen Fischer, Russell Barkley, Bradford A Navi. Identification and characterization of human NR4A2 polymorphisms in attention deficit hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 133B. issue 1. 2005-03-14. PMID:15635701. |
dopaminergic cells of the vta provide innervation to the prefrontal cortex, believed to be of major importance in the etiology of adhd, suggesting that nr4a2 is a potential candidate gene for adhd susceptibility. |
2005-03-14 |
2023-08-12 |
human |
| Kurt P Schulz, Jeffrey H Newcorn, Jin Fan, Cheuk Y Tang, Jeffrey M Halperi. Brain activation gradients in ventrolateral prefrontal cortex related to persistence of ADHD in adolescent boys. Journal of the American Academy of Child and Adolescent Psychiatry. vol 44. issue 1. 2005-03-01. PMID:15608543. |
brain activation gradients in ventrolateral prefrontal cortex related to persistence of adhd in adolescent boys. |
2005-03-01 |
2023-08-12 |
Not clear |
| Kurt P Schulz, Jeffrey H Newcorn, Jin Fan, Cheuk Y Tang, Jeffrey M Halperi. Brain activation gradients in ventrolateral prefrontal cortex related to persistence of ADHD in adolescent boys. Journal of the American Academy of Child and Adolescent Psychiatry. vol 44. issue 1. 2005-03-01. PMID:15608543. |
to explore the possible role that functional abnormalities of the prefrontal cortex and basal ganglia play in the persistence of attention-deficit/hyperactivity disorder (adhd) in adolescents aged 15 to 19 years. |
2005-03-01 |
2023-08-12 |
Not clear |
| Florence Lev. Synaptic gating and ADHD: a biological theory of comorbidity of ADHD and anxiety. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 9. 2004-10-18. PMID:15114344. |
in conclusion, a dual theory incorporating long-term tonic/phasic mesolimbic da relationships and secondly impairment of pfc and hippocampal inputs to synaptic gating of anxiety at the accumbens has implications for comorbidity in adhd, as well as for possible pharmacological interventions, utilizing either stimulant or axiolytic interventions. |
2004-10-18 |
2023-08-12 |
Not clear |
| D Viggiano, L A Ruocco, S Arcieri, A G Sadil. Involvement of norepinephrine in the control of activity and attentive processes in animal models of attention deficit hyperactivity disorder. Neural plasticity. vol 11. issue 1-2. 2004-09-07. PMID:15303310. |
functional and morphological studies in children affected by attention deficit hyperactivity disorder (adhd) suggest a prefrontal cortex (pfc) dysfunction. |
2004-09-07 |
2023-08-12 |
mouse |
| D Viggiano, L A Ruocco, S Arcieri, A G Sadil. Involvement of norepinephrine in the control of activity and attentive processes in animal models of attention deficit hyperactivity disorder. Neural plasticity. vol 11. issue 1-2. 2004-09-07. PMID:15303310. |
some animal models of adhd, such as spontaneously hypertensive rats (shr), show alterations in the pfc and in the da system. |
2004-09-07 |
2023-08-12 |
mouse |
| Ron M Sullivan, Wayne G Brak. What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behavioural brain research. vol 146. issue 1-2. 2004-01-29. PMID:14643458. |
the present review surveys a broad range of findings on the functions of the rodent prefrontal cortex (pfc) in the context of the known pathophysiology of attention-deficit/hyperactivity disorder (adhd). |
2004-01-29 |
2023-08-12 |
rat |
| Ron M Sullivan, Wayne G Brak. What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behavioural brain research. vol 146. issue 1-2. 2004-01-29. PMID:14643458. |
an overview of clinical findings concludes that dysfunction of the right pfc plays a critical role in adhd and that a number of early developmental factors conspire to increase the risk of the disorder. |
2004-01-29 |
2023-08-12 |
rat |
| Ron M Sullivan, Wayne G Brak. What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behavioural brain research. vol 146. issue 1-2. 2004-01-29. PMID:14643458. |
rodent studies are described which go far in explaining how the core processes which are deficient in adhd are mediated by the pfc and that the mesocortical dopamine (da) system plays a central role in modulating these functions. |
2004-01-29 |
2023-08-12 |
rat |
| Ron M Sullivan, Wayne G Brak. What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behavioural brain research. vol 146. issue 1-2. 2004-01-29. PMID:14643458. |
importantly, the pfc is highly vulnerable to a wide variety of early developmental insults, which parallel the known risk factors for adhd. |
2004-01-29 |
2023-08-12 |
rat |
| Ron M Sullivan, Wayne G Brak. What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behavioural brain research. vol 146. issue 1-2. 2004-01-29. PMID:14643458. |
abnormal development, particularly of the right pfc and its daergic afferents, is suggested to contribute directly to the core deficits of adhd through dysregulation of the right frontostriatal system. |
2004-01-29 |
2023-08-12 |
rat |