| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah Durston, Janna van Belle, Patrick de Zeeu. Differentiating frontostriatal and fronto-cerebellar circuits in attention-deficit/hyperactivity disorder. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:20965496. |
this article suggests a model for differentiating between interlinked reciprocal circuits with the prefrontal cortex in adhd. |
2011-09-29 |
2023-08-12 |
Not clear |
| Amy F T Arnsten, Steven R Pliszk. Catecholamine influences on prefrontal cortical function: relevance to treatment of attention deficit/hyperactivity disorder and related disorders. Pharmacology, biochemistry, and behavior. vol 99. issue 2. 2011-09-29. PMID:21295057. |
research has shown that the prefrontal cortex (pfc) is essential for the "top-down" regulation of attention, behavior, and emotion, and that this brain region is underactive in many patients with adhd. |
2011-09-29 |
2023-08-12 |
Not clear |
| Amy F T Arnsten, Steven R Pliszk. Catecholamine influences on prefrontal cortical function: relevance to treatment of attention deficit/hyperactivity disorder and related disorders. Pharmacology, biochemistry, and behavior. vol 99. issue 2. 2011-09-29. PMID:21295057. |
stronger pfc regulation of attention, behavior, and emotion likely contributes to the therapeutic effects of these medications for the treatment of adhd. |
2011-09-29 |
2023-08-12 |
Not clear |
| Nao J Gamo, Amy F T Arnste. Molecular modulation of prefrontal cortex: rational development of treatments for psychiatric disorders. Behavioral neuroscience. vol 125. issue 3. 2011-09-29. PMID:21480691. |
dysfunction of the prefrontal cortex (pfc) is a central feature of many psychiatric disorders, such as attention deficit hyperactivity disorder (adhd), posttraumatic stress disorder (ptsd), schizophrenia, and bipolar disorder. |
2011-09-29 |
2023-08-12 |
Not clear |
| Nao J Gamo, Amy F T Arnste. Molecular modulation of prefrontal cortex: rational development of treatments for psychiatric disorders. Behavioral neuroscience. vol 125. issue 3. 2011-09-29. PMID:21480691. |
examples of successful translation from animals to humans include guanfacine for the treatment of adhd and related pfc disorders, and prazosin for the treatment of ptsd. |
2011-09-29 |
2023-08-12 |
Not clear |
| Amy F T Arnste. Catecholamine influences on dorsolateral prefrontal cortical networks. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:21489408. |
all current pharmacological treatments for adhd facilitate catecholamine transmission, and basic research suggests that these compounds have prominent actions in the prefrontal cortex (pfc). |
2011-09-29 |
2023-08-12 |
Not clear |
| Amy F T Arnste. Catecholamine influences on dorsolateral prefrontal cortical networks. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:21489408. |
stronger pfc regulation of attention, behavior, and emotion likely contributes to the therapeutic effects of these medications for the treatment of adhd. |
2011-09-29 |
2023-08-12 |
Not clear |
| Natalia Del Campo, Samuel R Chamberlain, Barbara J Sahakian, Trevor W Robbin. The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:21550021. |
it is anticipated that the application of refined and novel positron emission tomography methodology will help to disentangle the overlapping and dissociable contributions of da and noradrenaline in the prefrontal cortex, thereby aiding our understanding of adhd and facilitating new treatments. |
2011-09-29 |
2023-08-12 |
human |
| Ariel Beth Brown, Joseph Biederman, Eve Valera, Nikos Makris, Alysa Doyle, Susan Whitfield-Gabrieli, Eric Mick, Thomas Spencer, Stephen Faraone, Larry Seidma. Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networks. Psychiatry research. vol 193. issue 1. 2011-08-03. PMID:21596533. |
our results yielded four principal findings: 1) association of the dat1 9r allele with adult adhd, 2) marginal dat1 association with task-related suppression in left medial pfc, 3) marginal genotype×diagnosis interaction in the dorsal anterior cingulate cortex, and 4) correlation of dmn suppression to adhd symptoms. |
2011-08-03 |
2023-08-12 |
human |
| I Paul-Jordanov, M Bechtold, C Gawrilo. Methylphenidate and if-then plans are comparable in modulating the P300 and increasing response inhibition in children with ADHD. Attention deficit and hyperactivity disorders. vol 2. issue 3. 2011-07-26. PMID:21432597. |
a disturbed functioning of the prefrontal cortex, the anterior cingulate cortex, and an accordingly reduced p300 presumably underlies executive function deficits of children with attention deficit hyperactivity disorder (adhd). |
2011-07-26 |
2023-08-12 |
Not clear |
| Benjamin Gronie. In vivo electrophysiological effects of methylphenidate in the prefrontal cortex: involvement of dopamine D1 and alpha 2 adrenergic receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 2. 2011-05-03. PMID:21146374. |
the prefrontal cortex (pfc) has a proven role in the expression of adhd. |
2011-05-03 |
2023-08-12 |
rat |
| Joseph A Helpern, Vitria Adisetiyo, Maria F Falangola, Caixia Hu, Adriana Di Martino, Kathleen Williams, Francisco X Castellanos, Jens H Jense. Preliminary evidence of altered gray and white matter microstructural development in the frontal lobe of adolescents with attention-deficit hyperactivity disorder: a diffusional kurtosis imaging study. Journal of magnetic resonance imaging : JMRI. vol 33. issue 1. 2011-04-15. PMID:21182116. |
to investigate non-gaussian water diffusion using diffusional kurtosis imaging (dki) to assess age effects on gray matter (gm) and white matter (wm) microstructural changes in the prefrontal cortex (pfc) of adolescents with attention-deficit hyperactivity disorder (adhd) compared to typically developing controls (tdc). |
2011-04-15 |
2023-08-12 |
Not clear |
| Francesco Amico, Jonathan Stauber, Nikolaos Koutsouleris, Thomas Frod. Anterior cingulate cortex gray matter abnormalities in adults with attention deficit hyperactivity disorder: a voxel-based morphometry study. Psychiatry research. vol 191. issue 1. 2011-02-24. PMID:21129938. |
using high-resolution mri, we tested the hypothesis that adult adhd patients exhibit gray and/or white matter volume (gmv, wmv) abnormalities in the prefrontal cortex (pfc), cingulate cortex (cc), hippocampus and amygdala, also evaluating putative associations between volumetric data and symptoms of adhd. |
2011-02-24 |
2023-08-12 |
Not clear |
| B E Depue, G C Burgess, E G Willcutt, L Ruzic, M T Banic. Inhibitory control of memory retrieval and motor processing associated with the right lateral prefrontal cortex: evidence from deficits in individuals with ADHD. Neuropsychologia. vol 48. issue 13. 2011-02-18. PMID:20863843. |
inhibitory control of memory retrieval and motor processing associated with the right lateral prefrontal cortex: evidence from deficits in individuals with adhd. |
2011-02-18 |
2023-08-12 |
Not clear |
| Lihui Wu, Qianlei Zhao, Xuchao Zhu, Min Peng, Chenyou Jia, Wei Wu, Jing Zheng, Xing Zhong W. A novel function of microRNA let-7d in regulation of galectin-3 expression in attention deficit hyperactivity disorder rat brain. Brain pathology (Zurich, Switzerland). vol 20. issue 6. 2011-01-26. PMID:20557304. |
as compared with wky rats, a lower level of galectin-3 was observed in shr brain prefrontal cortex (pfc), which was the major affected brain area of adhd. |
2011-01-26 |
2023-08-12 |
rat |
| Boong-Nyun Kim, Jae-Won Kim, Hyejin Kang, Soo-Churl Cho, Min-Sup Shin, Hee-Jeong Yoo, Soon-Beom Hong, Dong Soo Le. Regional differences in cerebral perfusion associated with the alpha-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorder. Journal of psychiatry & neuroscience : JPN. vol 35. issue 5. 2010-12-13. PMID:20731965. |
neurobiologic studies have suggested that dysregulation of central noradrenergic systems may be involved in the pathophysiology of attention deficit hyperactivity disorder (adhd), and it has been hypothesized that genetic changes in the norepinephrine pathways might contribute to dysfunction of the prefrontal cortex circuits in adhd. |
2010-12-13 |
2023-08-12 |
Not clear |
| Boong-Nyun Kim, Jae-Won Kim, Hyejin Kang, Soo-Churl Cho, Min-Sup Shin, Hee-Jeong Yoo, Soon-Beom Hong, Dong Soo Le. Regional differences in cerebral perfusion associated with the alpha-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorder. Journal of psychiatry & neuroscience : JPN. vol 35. issue 5. 2010-12-13. PMID:20731965. |
we previously reported decreased cerebral blood flow in the right lateral prefrontal cortex and both orbitofrontal cortices in children with adhd. |
2010-12-13 |
2023-08-12 |
Not clear |
| Ana Cubillo, Rozmin Halari, Christine Ecker, Vincent Giampietro, Eric Taylor, Katya Rubi. Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood Attention-Deficit Hyperactivity Disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching. Journal of psychiatric research. vol 44. issue 10. 2010-10-25. PMID:20060129. |
despite comparable task performance, adults with childhood adhd showed reduced activation compared to controls in bilateral inferior prefrontal cortex, caudate and thalamus during both tasks, as well as in left parietal lobe during the switch task. |
2010-10-25 |
2023-08-12 |
Not clear |
| Amori Yee Mikami, Matthew D Lerner, Marissa Swaim Griggs, Alison McGrath, Casey D Calhou. Parental influence on children with attention-deficit/hyperactivity disorder: II. Results of a pilot intervention training parents as friendship coaches for children. Journal of abnormal child psychology. vol 38. issue 6. 2010-10-19. PMID:20339911. |
parents of 62 children with adhd (ages 6-10; 68% male) were randomly assigned to receive the parental friendship coaching (pfc) intervention, or to be in a no-treatment control group. |
2010-10-19 |
2023-08-12 |
Not clear |
| Margaret A Sheridan, Stephen Hinshaw, Mark D'Esposit. Stimulant medication and prefrontal functional connectivity during working memory in ADHD: a preliminary report. Journal of attention disorders. vol 14. issue 1. 2010-09-27. PMID:20576647. |
recent theoretical and empirical work suggests that while unmedicated, children with adhd have a deficit in subcortical processing that leads to greater and more varied prefrontal cortical (pfc) activation, compared to (a) age-matched control participants and (b) their own brain activity while on stimulant medication. |
2010-09-27 |
2023-08-12 |
human |