| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
following a prolonged cocaine self-administration binge, dopamine efflux in the nucleus accumbens is attenuated and behaviors emerge that are indicative of anhedonia and anxiety. |
2001-01-11 |
2023-08-12 |
rat |
| A Hein. [Psychopathological correlates of dopaminergic dysfunction in alcoholic and schizophrenic patients]. Der Nervenarzt. vol 70. issue 5. 1999-08-12. PMID:10407835. |
schizophrenics with neuroleptic blockade of striatal dopamine d2 receptors displayed psychomotor slowing and reduced motivation, but not anhedonia. |
1999-08-12 |
2023-08-12 |
Not clear |
| A Hein. [Psychopathological correlates of dopaminergic dysfunction in alcoholic and schizophrenic patients]. Der Nervenarzt. vol 70. issue 5. 1999-08-12. PMID:10407835. |
these observations indicate that a dysfunction of stimulus-dependent dopamine release may be associated with motivational deficits caused by a reduction in incentive salience, but not with anhedonia. |
1999-08-12 |
2023-08-12 |
Not clear |
| G Di Chiara, G Tand. Blunting of reactivity of dopamine transmission to palatable food: a biochemical marker of anhedonia in the CMS model? Psychopharmacology. vol 134. issue 4. 1998-03-17. PMID:9452172. |
blunting of reactivity of dopamine transmission to palatable food: a biochemical marker of anhedonia in the cms model? |
1998-03-17 |
2023-08-12 |
Not clear |
| J D Salamone, M S Cousins, B J Snyde. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168269. |
behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. |
1997-07-21 |
2023-08-12 |
Not clear |
| S C Risc. Pathophysiology of schizophrenia and the role of newer antipsychotics. Pharmacotherapy. vol 16. issue 1 Pt 2. 1996-09-17. PMID:8778681. |
the dopamine deficit may be related to the negative symptoms (blunted affect, anhedonia, asociality, inability to initiate and carry out complex tasks to completion) of schizophrenia, whereas the dopamine excess may be responsible for the positive symptoms (hallucinations, delusions, and thought disorder). |
1996-09-17 |
2023-08-12 |
human |
| M Papp, P Willner, R Musca. Behavioural sensitization to a dopamine agonist is associated with reversal of stress-induced anhedonia. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870877. |
behavioural sensitization to a dopamine agonist is associated with reversal of stress-induced anhedonia. |
1995-03-29 |
2023-08-12 |
rat |
| M Papp, V Klimek, P Willne. Parallel changes in dopamine D2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. Psychopharmacology. vol 115. issue 4. 1995-03-28. PMID:7871087. |
parallel changes in dopamine d2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. |
1995-03-28 |
2023-08-12 |
rat |
| A Heinz, L G Schmidt, F M Reischie. Anhedonia in schizophrenic, depressed, or alcohol-dependent patients--neurobiological correlates. Pharmacopsychiatry. vol 27 Suppl 1. 1995-01-04. PMID:7984706. |
in order to further investigate the correlation of anhedonia, psychomotor slowing, and the status of the dopaminergic reward system, the density of striatal dopamine d2-receptors can be measured by ibzm-spect and related to psychomotor slowing and anhedonia in different states of schizophrenic, depressive, and alcohol-dependent patients. |
1995-01-04 |
2023-08-12 |
Not clear |
| P Willner, R Muscat, M Pap. Chronic mild stress-induced anhedonia: a realistic animal model of depression. Neuroscience and biobehavioral reviews. vol 16. issue 4. 1993-02-11. PMID:1480349. |
this paper reviews the validity of chronic mild stress-induced anhedonia as an animal model of depression, and the evidence that changes in hedonic responsiveness in this model are mediated by changes in the sensitivity of dopamine d2 receptors in the nucleus accumbens. |
1993-02-11 |
2023-08-11 |
rat |
| G F Koob, F Weis. Neuropharmacology of cocaine and ethanol dependence. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism. vol 10. 1992-06-22. PMID:1350359. |
chronic cocaine produces increases in brain reward thresholds that may reflect the "dysphoria" and anhedonia associated with cocaine dependence and suggests a dysregulation of brain reward systems possibly involving dopamine. |
1992-06-22 |
2023-08-11 |
rat |
| E O Hammond, M L Torok, A Ettenber. Different patterns of behavior produced by haloperidol, pentobarbital, and dantrolene in tests of unconditioned locomotion and operant responding. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1876659. |
rather, the profile of this deterioration is consistent with the anhedonia hypothesis of neuroleptic action and supports the view that dopamine neurons are involved in the biological basis of food reward. |
1991-09-26 |
2023-08-11 |
rat |
| H M Van Praag, G M Asnis, R S Kahn, S L Brown, M Korn, J M Friedman, S Wetzle. Nosological tunnel vision in biological psychiatry. A plea for a functional psychopathology. Annals of the New York Academy of Sciences. vol 600. 1991-01-14. PMID:2252329. |
signs of diminished dopamine, serotonine, and noradrenaline metabolism, as have been found in psychiatric disorders, are not disorder-specific, but rather are related to psychopathological dimensions; i.e., hypoactivity/inertia; increased aggression/anxiety and anhedonia, independent of the nosological framework in which these dysfunctions occur (van praag et al. |
1991-01-14 |
2023-08-11 |
Not clear |
| K C Berridge, I L Venier, T E Robinso. Taste reactivity analysis of 6-hydroxydopamine-induced aphagia: implications for arousal and anhedonia hypotheses of dopamine function. Behavioral neuroscience. vol 103. issue 1. 1989-04-24. PMID:2493791. |
taste reactivity analysis of 6-hydroxydopamine-induced aphagia: implications for arousal and anhedonia hypotheses of dopamine function. |
1989-04-24 |
2023-08-11 |
rat |
| K C Berridge, I L Venier, T E Robinso. Taste reactivity analysis of 6-hydroxydopamine-induced aphagia: implications for arousal and anhedonia hypotheses of dopamine function. Behavioral neuroscience. vol 103. issue 1. 1989-04-24. PMID:2493791. |
the anhedonia hypothesis suggests that dopamine systems amplify the hedonic impact of positive reinforcers. |
1989-04-24 |
2023-08-11 |
rat |
| R J Care. An examination of parkinsonian versus anhedonia contributions to self-stimulation impairments induced by dopamine dysfunction. Behavioural brain research. vol 22. issue 2. 1987-02-10. PMID:3024663. |
an examination of parkinsonian versus anhedonia contributions to self-stimulation impairments induced by dopamine dysfunction. |
1987-02-10 |
2023-08-11 |
Not clear |
| P Carnoy, P Soubrie, A J Puech, P Simo. Performance deficit induced by low doses of dopamine agonists in rats. Toward a model for approaching the neurobiology of negative schizophrenic symptomatology? Biological psychiatry. vol 21. issue 1. 1986-03-13. PMID:2867789. |
if this deficit is due to decreased dopaminergic transmission produced by low doses of dopamine agonists, our model might suggest that some symptoms of schizophrenia (anhedonia for instance) are not incompatible with deficient dopaminergic transmission. |
1986-03-13 |
2023-08-11 |
rat |
| H C Fibige. The neurobiological substrates of depression in Parkinson's disease: a hypothesis. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 11. issue 1 Suppl. 1984-05-29. PMID:6324981. |
anhedonia) is a cardinal feature of clinical depression, and since the mesolimbic and mesocortical dopamine projections have been shown to degenerate in parkinson's disease, it is suggested that damage to these reward-related systems may contribute directly to the high incidence of depression that has been reported in this disease. |
1984-05-29 |
2023-08-12 |
Not clear |