| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Berger, E Mezey, K P Clancy, G Harta, R M Wright, J E Repine, R H Brown, M Brownstein, D Patterso. Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis. Somatic cell and molecular genetics. vol 21. issue 2. 1995-10-23. PMID:7570184. |
recently, point mutations in superoxide dismutase 1 (sod1) have been shown to lead to a subset of autosomal dominantly inherited familial amyotrophic lateral sclerosis (als). |
1995-10-23 |
2023-08-12 |
human |
| K Nishiyama, S Murayama, J Shimizu, Y Ohya, S Kwak, K Asayama, I Kanazaw. Cu/Zn superoxide dismutase-like immunoreactivity is present in Lewy bodies from Parkinson disease: a light and electron microscopic immunocytochemical study. Acta neuropathologica. vol 89. issue 6. 1995-10-17. PMID:7676802. |
copper-zinc superoxide dismutase (sod1)-like immunoreactivity has been demonstrated in lewy body-like inclusions (lis) in brain tissues from patients with familial and sporadic amyotrophic lateral sclerosis. |
1995-10-17 |
2023-08-12 |
Not clear |
| H X Deng, J A Tainer, H Mitsumoto, A Ohnishi, X He, W Y Hung, Y Zhao, T Juneja, A Hentati, T Siddiqu. Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis. Human molecular genetics. vol 4. issue 6. 1995-10-05. PMID:7655471. |
two novel sod1 mutations in patients with familial amyotrophic lateral sclerosis. |
1995-10-05 |
2023-08-12 |
Not clear |
| C T Jones, R J Swingler, S A Simpson, D J Broc. Superoxide dismutase mutations in an unselected cohort of Scottish amyotrophic lateral sclerosis patients. Journal of medical genetics. vol 32. issue 4. 1995-09-18. PMID:7643359. |
mutations in the cu/zn superoxide dismutase (sod1) gene are responsible for some cases of familial amyotrophic lateral sclerosis (als). |
1995-09-18 |
2023-08-12 |
Not clear |
| O Bandmann, M B Davis, C D Marsden, A E Hardin. Sequence of the superoxide dismutase 1 (SOD 1) gene in familial Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 59. issue 1. 1995-08-15. PMID:7608718. |
mutations in the superoxide dismutase 1 (sod1) gene have been detected in affected members of some families with familial amyotrophic lateral sclerosis. |
1995-08-15 |
2023-08-12 |
Not clear |
| O Bandmann, M B Davis, C D Marsden, A E Hardin. Sequence of the superoxide dismutase 1 (SOD 1) gene in familial Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 59. issue 1. 1995-08-15. PMID:7608718. |
to evaluate the possibility of a shared genetic defect in amyotrophic lateral sclerosis and parkinson's disease, the sod1 gene was sequenced in index patients with familial parkinson's disease from 23 families. |
1995-08-15 |
2023-08-12 |
Not clear |
| P C Wong, C A Pardo, D R Borchelt, M K Lee, N G Copeland, N A Jenkins, S S Sisodia, D W Cleveland, D L Pric. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. vol 14. issue 6. 1995-08-11. PMID:7605627. |
mutations in cu/zn superoxide dismutase (sod1) cause a subset of cases of familial amyotrophic lateral sclerosis. |
1995-08-11 |
2023-08-12 |
mouse |
| K Nakashima, Y Watanabe, N Kuno, E Nanba, K Takahash. Abnormality of Cu/Zn superoxide dismutase (SOD1) activity in Japanese familial amyotrophic lateral sclerosis with two base pair deletion in the SOD1 gene. Neurology. vol 45. issue 5. 1995-06-15. PMID:7746377. |
abnormality of cu/zn superoxide dismutase (sod1) activity in japanese familial amyotrophic lateral sclerosis with two base pair deletion in the sod1 gene. |
1995-06-15 |
2023-08-12 |
Not clear |
| A C Bowling, E E Barkowski, D McKenna-Yasek, P Sapp, H R Horvitz, M F Beal, R H Brow. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. Journal of neurochemistry. vol 64. issue 5. 1995-05-23. PMID:7722523. |
some cases of autosomal-dominant familial amyotrophic lateral sclerosis (fals) have been associated with mutations in sod1, the gene that encodes cu/zn superoxide dismutase (cu/zn sod). |
1995-05-23 |
2023-08-12 |
Not clear |
| S Rabizadeh, E B Gralla, D R Borchelt, R Gwinn, J S Valentine, S Sisodia, P Wong, M Lee, H Hahn, D E Bredese. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 7. 1995-05-11. PMID:7708768. |
familial amyotrophic lateral sclerosis (fals) is associated with mutations in sod1, the gene encoding copper/zinc superoxide dismutase (cuznsod). |
1995-05-11 |
2023-08-12 |
Not clear |
| J Puymirat, L Cossette, F Gosselin, J P Bouchar. Red blood cell Cu/Zn superoxide dismutase activity in sporadic amyotrophic lateral sclerosis. Journal of the neurological sciences. vol 127. issue 1. 1995-04-28. PMID:7699387. |
to determine the possible role of cu/zn superoxide dismutase (sod1) in the pathophysiology of sporadic amyotrophic lateral sclerosis (sals), we measured sod1 activity in red blood cell lysates in patients with sals. |
1995-04-28 |
2023-08-12 |
Not clear |
| S A O'Reilly, J Roedica, D Nagy, R A Hallewell, K Alderson, S L Marklund, J Kuby, P D Kushne. Motor neuron-astrocyte interactions and levels of Cu,Zn superoxide dismutase in sporadic amyotrophic lateral sclerosis. Experimental neurology. vol 131. issue 2. 1995-04-27. PMID:7895821. |
copper, zinc superoxide dismutase (sod1) is involved in neutralizing free radicals within cells, and mutant forms of the enzyme have recently been shown to occur in about 20% of familial cases of amyotrophic lateral sclerosis (als). |
1995-04-27 |
2023-08-12 |
Not clear |
| C T Jones, P J Shaw, G Chari, D J Broc. Identification of a novel exon 4 SOD1 mutation in a sporadic amyotrophic lateral sclerosis patient. Molecular and cellular probes. vol 8. issue 4. 1995-03-30. PMID:7870076. |
identification of a novel exon 4 sod1 mutation in a sporadic amyotrophic lateral sclerosis patient. |
1995-03-30 |
2023-08-12 |
Not clear |
| C T Jones, P J Shaw, G Chari, D J Broc. Identification of a novel exon 4 SOD1 mutation in a sporadic amyotrophic lateral sclerosis patient. Molecular and cellular probes. vol 8. issue 4. 1995-03-30. PMID:7870076. |
we have been screening a cohort of 46 sporadic and 10 familial amyotrophic lateral sclerosis patients for mutations in the superoxide dismutase gene (sod1) using a combination of sscp and direct pcr sequencing. |
1995-03-30 |
2023-08-12 |
Not clear |
| C A Pardo, Z Xu, D R Borchelt, D L Price, S S Sisodia, D W Clevelan. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 4. 1995-03-20. PMID:7862672. |
mutation in superoxide dismutase 1 (sod1), a cu/zn enzyme that removes oxygen radicals and protects against oxidative injury, has been implicated in some cases of familial amyotrophic lateral sclerosis (fals). |
1995-03-20 |
2023-08-12 |
mouse |
| D R Borchelt, M Guarnieri, P C Wong, M K Lee, H S Slunt, Z S Xu, S S Sisodia, D L Price, D W Clevelan. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of biological chemistry. vol 270. issue 7. 1995-03-15. PMID:7852409. |
mutations in superoxide dismutase 1 (sod1) have been linked to familial amyotrophic lateral sclerosis, a dominantly inherited motor neuron disorder of midlife. |
1995-03-15 |
2023-08-12 |
mouse |
| D R Borchelt, M Guarnieri, P C Wong, M K Lee, H S Slunt, Z S Xu, S S Sisodia, D L Price, D W Clevelan. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of biological chemistry. vol 270. issue 7. 1995-03-15. PMID:7852409. |
these findings, together with observations that many mutant sod1 subunits retain significant stability and activity, suggest that motor neuron damage in familial amyotrophic lateral sclerosis is caused by the acquisition of injurious properties by mutant sod1 subunits. |
1995-03-15 |
2023-08-12 |
mouse |
| H Takahashi, T Makifuchi, R Nakano, S Sato, T Inuzuka, K Sakimura, M Mishina, Y Honma, S Tsuji, F Ikut. Familial amyotrophic lateral sclerosis with a mutation in the Cu/Zn superoxide dismutase gene. Acta neuropathologica. vol 88. issue 2. 1995-01-04. PMID:7985500. |
several missense mutations within exons 1, 2, 4 and 5 of the gene for cu/zn-binding superoxide dismutase (sod1) have been discovered to be involved in the development of chromosome 21q-linked familial amyotrophic lateral sclerosis (fals). |
1995-01-04 |
2023-08-12 |
Not clear |
| P Gregor, S M Gaston, X Yang, J P O'Regan, D R Rosen, R E Tanzi, D Patterson, J L Haines, H R Horvitz, G R Uh. Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21. Human genetics. vol 94. issue 5. 1994-12-15. PMID:7959697. |
the human glur5 gene is located near the familial amyotrophic lateral sclerosis (fals) locus; linkage analysis of glur5 sslps in fals pedigrees yielded negative lod scores, consistent with the recent association of the fals locus with the sod1 gene. |
1994-12-15 |
2023-08-12 |
human |
| D R Rosen, A C Bowling, D Patterson, T B Usdin, P Sapp, E Mezey, D McKenna-Yasek, J O'Regan, Z Rahmani, R J Ferrant. A frequent ala 4 to val superoxide dismutase-1 mutation is associated with a rapidly progressive familial amyotrophic lateral sclerosis. Human molecular genetics. vol 3. issue 6. 1994-11-30. PMID:7951249. |
familial amyotrophic lateral sclerosis (fals), a degenerative disorder of motor neurons, is associated with mutations in the cu/zn superoxide dismutase gene sod1 in some affected families. |
1994-11-30 |
2023-08-12 |
Not clear |