| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teuta Domi, Paride Schito, Giacomo Sferruzza, Tommaso Russo, Laura Pozzi, Federica Agosta, Paola Carrera, Nilo Riva, Massimo Filippi, Angelo Quattrini, Yuri Matteo Falzon. Unveiling the SOD1-mediated ALS phenotype: insights from a comprehensive meta-analysis. Journal of neurology. 2023-11-06. PMID:37930481. |
amyotrophic lateral sclerosis associated with mutations in sod1 (sod1-als) might be susceptible to specific treatment. |
2023-11-06 |
2023-11-08 |
Not clear |
| Peter H Kin. Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis: a narrative review. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843208. |
the first is to summarize some of the biomarkers identified in human amyotrophic lateral sclerosis muscle that have a clinicopathological correlation with disease activity, evidence of a similar dysregulation in the sod1 |
2023-10-16 |
2023-11-08 |
human |
| Aziza Rahman, Bondeepa Saikia, Anupaul Barua. Physical chemistry chemical physics : PCCP. 2023-10-02. PMID:37782142. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease, the familial form (fals) of which is often cognate to mutations in the antioxidant enzyme cu/zn superoxide dismutase 1 (sod1) leading to misfolding and aggregation. |
2023-10-02 |
2023-10-07 |
Not clear |
| Konstantinos Tsioras, Kevin C Smith, Seby L Edassery, Mehraveh Garjani, Yichen Li, Chloe Williams, Elizabeth D McKenna, Wenxuan Guo, Anika P Wilen, Timothy J Hark, Stefan L Marklund, Lyle W Ostrow, Jonathan D Gilthorpe, Justin K Ichida, Robert G Kalb, Jeffrey N Savas, Evangelos Kiskini. Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis. Cell reports. 2023-09-30. PMID:37776851. |
mutations in sod1 cause amyotrophic lateral sclerosis (als) through gain-of-function effects, yet the mechanisms by which misfolded mutant sod1 (mutsod1) protein impairs human motor neurons (mns) remain unclear. |
2023-09-30 |
2023-10-07 |
human |
| Jacob I Ayers, Guilian Xu, Qing Lu, Kristy Dillon, Susan Fromholt, David R Borchel. Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice. Viruses. vol 15. issue 9. 2023-09-28. PMID:37766226. |
mutations in superoxide dismutase 1 (sod1) that are associated with amyotrophic lateral sclerosis (als) cause its misfolding and aggregation. |
2023-09-28 |
2023-10-07 |
mouse |
| Gabriel S Trajano, Lucas B R Orssatto, Pamela A McCombe, Warwick Rivlin, Lily Tang, Robert D Henderso. Longitudinal changes in intrinsic motoneuron excitability in amyotrophic lateral sclerosis are dependent on disease progression. The Journal of physiology. 2023-09-28. PMID:37768183. |
increased amplitude of persistent inward currents (pics) is observed in pre-symptomatic genetically modified sod1 mice models of amyotrophic lateral sclerosis (als). |
2023-09-28 |
2023-10-07 |
mouse |
| Teng Guan, Ting Zhou, Xiaosha Zhang, Ying Guo, Chaoxian Yang, Justin Lin, Jiasi Vicky Zhang, Yongquan Cheng, Hassan Marzban, Yu Tian Wang, Jiming Kon. Selective removal of misfolded SOD1 delays disease onset in a mouse model of amyotrophic lateral sclerosis. Cellular and molecular life sciences : CMLS. vol 80. issue 10. 2023-09-26. PMID:37752364. |
selective removal of misfolded sod1 delays disease onset in a mouse model of amyotrophic lateral sclerosis. |
2023-09-26 |
2023-10-07 |
mouse |
| Sara Hernández, Sara Salvany, Anna Casanovas, Lídia Piedrafita, M Clara Soto-Bernardini, Olga Tarabal, Alba Blasco, Sílvia Gras, Alaó Gatius, Markus H Schwab, Jordi Calderó, Josep E Esquerd. Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1 Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023-09-21. PMID:37733208. |
persistent nrg1 type iii overexpression in spinal motor neurons has no therapeutic effect on als-related pathology in sod1 amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease affecting upper and lower motor neurons (mns). |
2023-09-21 |
2023-10-07 |
mouse |
| P Corcia, P Vourc'h, E Bernard, J Cassereau, P Codron, M-C Fleury, N Guy, K Mouzat, P-F Pradat, M-H Soriani, P Couratie. French National Protocol for genetic of amyotrophic lateral sclerosis. Revue neurologique. 2023-09-21. PMID:37735015. |
relationships between genes and amyotrophic lateral sclerosis (als) have been widely accepted since the first studies highlighting pathogenic mutations in the sod1 gene 30years ago. |
2023-09-21 |
2023-10-07 |
Not clear |
| Ana Laura M R Tomiyama, Luciana Politti Cartarozzi, Lilian de Oliveira Coser, Gabriela Bortolança Chiarotto, Alexandre L R Oliveir. Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1 Frontiers in cellular neuroscience. vol 17. 2023-09-15. PMID:37711512. |
neuroprotection by upregulation of the major histocompatibility complex class i (mhc i) in sod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease that progressively affects motoneurons, causing muscle atrophy and evolving to death. |
2023-09-15 |
2023-10-07 |
Not clear |
| Venkatesan Santhanam, Priya Modi, Umesh K Mishra, Ishrat Jahan, Namakkal G Ramesh, Shashank Dee. Rational design and synthesis of novel triazole- and tetrazole-fused iminosugars as potential inhibitors of amyotrophic lateral sclerosis (ALS) linked SOD1 aggregation. International journal of biological macromolecules. 2023-09-15. PMID:37714236. |
rational design and synthesis of novel triazole- and tetrazole-fused iminosugars as potential inhibitors of amyotrophic lateral sclerosis (als) linked sod1 aggregation. |
2023-09-15 |
2023-10-07 |
Not clear |
| Daniela Gerovska, Julie B Noer, Yating Qin, Quratul Ain, Donjetë Januzi, Matthias Schwab, Otto W Witte, Marcos J Araúzo-Bravo, Alexandra Kret. A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1 Cell & bioscience. vol 13. issue 1. 2023-09-13. PMID:37705092. |
a distinct circular dna profile intersects with proteome changes in the genotoxic stress-related hsod1 numerous genes, including sod1, mutated in familial and sporadic amyotrophic lateral sclerosis (f/sals) share a role in dna damage and repair, emphasizing genome disintegration in als. |
2023-09-13 |
2023-10-07 |
Not clear |
| Ilaria Martinelli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Laura Ferri, Cristina Moglia, Umberto Manera, Luca Solero, Rosario Vasta, Antonio Canosa, Maurizio Grassano, Maura Brunetti, Letizia Mazzini, Fabiola De Marchi, Cecilia Simonini, Nicola Fini, Marco Vinceti, Marcello Pinti, Adriano Chiò, Andrea Calvo, Jessica Mandriol. Predictors for progression in amyotrophic lateral sclerosis associated to SOD1 mutation: insight from two population-based registries. Journal of neurology. 2023-09-05. PMID:37668704. |
predictors for progression in amyotrophic lateral sclerosis associated to sod1 mutation: insight from two population-based registries. |
2023-09-05 |
2023-09-07 |
Not clear |
| Ilaria Martinelli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Laura Ferri, Cristina Moglia, Umberto Manera, Luca Solero, Rosario Vasta, Antonio Canosa, Maurizio Grassano, Maura Brunetti, Letizia Mazzini, Fabiola De Marchi, Cecilia Simonini, Nicola Fini, Marco Vinceti, Marcello Pinti, Adriano Chiò, Andrea Calvo, Jessica Mandriol. Predictors for progression in amyotrophic lateral sclerosis associated to SOD1 mutation: insight from two population-based registries. Journal of neurology. 2023-09-05. PMID:37668704. |
uncovering distinct features and trajectories of amyotrophic lateral sclerosis (als) associated with sod1 mutations (sod1-als) can provide valuable insights for patient' counseling and stratification for trials, and interventions timing. |
2023-09-05 |
2023-09-07 |
Not clear |
| Akhtar Atiya, Abdullatif Bin Muhsinah, Mohammed Alrouji, Fahad Alhumaydhi, Waleed Al Abdulmonem, Mohammad Abdullah Aljasir, Sharaf E Sharaf, Mohammad Furkan, Rizwan Hasan Khan, Moyad Shahwan, Anas Shams. Unveiling promising inhibitors of superoxide dismutase 1 (SOD1) for therapeutic interventions. International journal of biological macromolecules. 2023-09-04. PMID:37666395. |
any dysregulation of sod1 activity is linked with cancer pathogenesis and neurodegenerative disorders, such as amyotrophic lateral sclerosis (als). |
2023-09-04 |
2023-09-07 |
Not clear |
| Lisa Morichon, Christophe Hirtz, Laurent Tiers, Alexandre Mezghrani, Cédric Raoul, Florence Esselin, Elisa De La Cruz, Jean-Pierre Julien, William Camu, Sylvain Lehman. Ultrasensitive digital immunoassays for SOD1 conformation in amyotrophic lateral sclerosis. Bioanalysis. 2023-08-31. PMID:37650499. |
ultrasensitive digital immunoassays for sod1 conformation in amyotrophic lateral sclerosis. |
2023-08-31 |
2023-09-07 |
Not clear |
| Soledad Marton, Ernesto Miquel, Joaquín Acosta-Rodríguez, Santiago Fontenla, Gabriela Libisch, Patricia Cassin. SOD1 ASN neuro. vol 15. 2023-08-30. PMID:37644868. |
sod1 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (mn) degeneration. |
2023-08-30 |
2023-09-07 |
Not clear |
| Shilpa Sharma, Vijay Raj Tomar, Shashank Dee. Mechanism of the interaction of toxic SOD1 fibrils with two potent polyphenols: curcumin and quercetin. Physical chemistry chemical physics : PCCP. 2023-08-21. PMID:37602388. |
amyotrophic lateral sclerosis (als) is a debilitating neurodegenerative disease commonly caused due to the aggregation of superoxide dismutase 1 (sod1) protein. |
2023-08-21 |
2023-09-07 |
Not clear |
| José R Monteiro Neto, Gabriela D Ribeiro, Rayne S S Magalhães, Cristian Follmer, Tiago F Outeiro, Elis C A Eleutheri. Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis. Biochimica et biophysica acta. Molecular basis of disease. 2023-08-09. PMID:37558009. |
different sod1 proteoforms are implicated## in both familial and sporadic cases of amyotrophic lateral sclerosis (als), an aging-associated disease that affects motor neurons. |
2023-08-09 |
2023-08-16 |
human |
| Shamchal Bakavayev, Alexandra Stavsky, Shirel Argueti-Ostrovsky, Galit Yehezkel, Yael Fridmann-Sirkis, Zeev Barak, Daniel Gitler, Adrian Israelson, Stanislav Enge. Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis. Brain : a journal of neurology. 2023-07-03. PMID:37394908. |
blocking an epitope of misfolded sod1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis. |
2023-07-03 |
2023-08-14 |
mouse |