| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anas Shamsi, Debarati DasGupta, Fahad A Alhumaydhi, Mohd Shahnawaz Khan, Suliman A Alsagaby, Waleed Al Abdulmonem, Md Imtaiyaz Hassan, Dharmendra Kumar Yada. Inhibition of MARK4 by serotonin as an attractive therapeutic approach to combat Alzheimer's disease and neuroinflammation. RSC medicinal chemistry. vol 13. issue 6. 2022-07-11. PMID:35814926. |
inhibition of mark4 by serotonin as an attractive therapeutic approach to combat alzheimer's disease and neuroinflammation. |
2022-07-11 |
2023-08-14 |
Not clear |
| L S Schneider, M Laudon, T Nir, J Caceres, G Ianniciello, M Capulli, N Zisape. A Polymorphism Cluster at the 2q12 locus May Predict Response to Piromelatine in Patients with Mild Alzheimer's Disease. The journal of prevention of Alzheimer's disease. vol 9. issue 2. 2022-05-11. PMID:35542997. |
piromelatine is a novel melatonin mt1/2/3 and serotonin 5-ht-1a/1d receptors agonist developed for mild alzheimer's disease (ad). |
2022-05-11 |
2023-08-13 |
human |
| Mithula Sivasaravanaparan, Louise Ørum Olesen, Maurizio Severino, Maurizio Christian Ulrich von Linstow, Kate Lykke Lambertsen, Jan Bert Gramsbergen, Jørgen Hasselstrøm, Athanasios Metaxas, Ove Wiborg, Bente Finse. Efficacy of Chronic Paroxetine Treatment in Mitigating Amyloid Pathology and Microgliosis in APPSWE/PS1ΔE9 Transgenic Mice. Journal of Alzheimer's disease : JAD. 2022-03-28. PMID:35342093. |
modulation of serotonergic signaling by treatment with selective serotonin reuptake inhibitors (ssris) has been suggested to mitigate amyloid-β (aβ) pathology in alzheimer's disease, in addition to exerting an anti-depressant action. |
2022-03-28 |
2023-08-13 |
mouse |
| Emma Aaldijk, Yannick Vermeire. The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: a narrative review. Ageing research reviews. 2022-01-06. PMID:34990844. |
the role of serotonin within the microbiota-gut-brain axis in the development of alzheimer's disease: a narrative review. |
2022-01-06 |
2023-08-13 |
mouse |
| Yi Kuan Du, Yue Xiao, Shao Min Zhong, Yi Xing Huang, Qian Wen Chen, Yu Qi Zhou, Jin Yan Guo, Chun Yan. Study on the Mechanism of Acori Graminei Rhizoma in the Treatment of Alzheimer's Disease Based on Network Pharmacology and Molecular Docking. BioMed research international. vol 2021. 2022-01-03. PMID:34977242. |
go analysis and kegg analysis showed that there were 195 go items and 30 ad-related pathways, including alzheimer's disease pathway, serotonin synapse, estrogen signaling pathway, dopaminergic synapse, and pi3k-akt signaling pathway. |
2022-01-03 |
2023-08-13 |
Not clear |
| Christian Ulrich von Linstow, Jonas Waider, Marianne Skov-Skov Bergh, Marco Anzalone, Cecilie Madsen, Aina Battle Nicolau, Martin Wirenfeldt, Klaus-Peter Lesch, Bente Finse. The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2021-12-20. PMID:34924373. |
the combined effects of amyloidosis and serotonin deficiency by tryptophan hydroxylase-2 knockout impacts viability of the app/ps1 mouse model of alzheimer's disease. |
2021-12-20 |
2023-08-13 |
mouse |
| Christian Ulrich von Linstow, Jonas Waider, Marianne Skov-Skov Bergh, Marco Anzalone, Cecilie Madsen, Aina Battle Nicolau, Martin Wirenfeldt, Klaus-Peter Lesch, Bente Finse. The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2021-12-20. PMID:34924373. |
a decline of brain serotonin (5-ht) is held responsible for the changes in mood that can be observed in alzheimer's disease (ad). |
2021-12-20 |
2023-08-13 |
mouse |
| Madeline J Nykamp, Charles F Zorumski, Angela M Reiersen, Ginger E Nicol, John Cirrito, Eric J Lenz. Opportunities for Drug Repurposing of Serotonin Reuptake Inhibitors: Potential Uses in Inflammation, Infection, Cancer, Neuroprotection, and Alzheimer's Disease Prevention. Pharmacopsychiatry. 2021-12-07. PMID:34875696. |
opportunities for drug repurposing of serotonin reuptake inhibitors: potential uses in inflammation, infection, cancer, neuroprotection, and alzheimer's disease prevention. |
2021-12-07 |
2023-08-13 |
Not clear |
| Ethan S Burstei. Relevance of 5-HT CNS drugs. vol 35. issue 7. 2021-11-25. PMID:34224112. |
relevance of 5-ht psychosis occurs across a wide variety of dementias with differing etiologies, including alzheimer's dementia, parkinson's dementia, lewy body dementia, frontotemporal dementia, and vascular dementia. |
2021-11-25 |
2023-08-13 |
Not clear |
| Katarzyna Kucwaj-Brysz, Hanna Baltrukevich, Kinga Czarnota, Jadwiga Handzli. Chemical update on the potential for serotonin 5-HT Bioorganic & medicinal chemistry letters. vol 49. 2021-11-22. PMID:34311086. |
chemical update on the potential for serotonin 5-ht despite the better understanding of the mechanisms underlying alzheimer's disease (ad) and launched clinical trials, no ad-modifying treatment based on a synthetic drug has been introduced for almost twenty years. |
2021-11-22 |
2023-08-13 |
Not clear |
| Tomasz Wichur, Anna Pasieka, Justyna Godyń, Dawid Panek, Izabella Góral, Gniewomir Latacz, Ewelina Honkisz-Orzechowska, Adam Bucki, Agata Siwek, Monika Głuch-Lutwin, Damijan Knez, Xavier Brazzolotto, Stanislav Gobec, Marcin Kołaczkowski, Raimon Sabate, Barbara Malawska, Anna Więckowsk. Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT European journal of medicinal chemistry. vol 225. 2021-11-11. PMID:34461507. |
discovery of 1-(phenylsulfonyl)-1h-indole-based multifunctional ligands targeting cholinesterases and 5-ht multifunctional ligands as an essential variant of polypharmacology are promising candidates for the treatment of multi-factorial diseases like alzheimer's disease. |
2021-11-11 |
2023-08-13 |
Not clear |
| Tomasz Wichur, Justyna Godyń, Izabella Góral, Gniewomir Latacz, Adam Bucki, Agata Siwek, Monika Głuch-Lutwin, Barbara Mordyl, Joanna Śniecikowska, Maria Walczak, Damijan Knez, Marko Jukič, Kinga Sałat, Stanislav Gobec, Marcin Kołaczkowski, Barbara Malawska, Xavier Brazzolotto, Anna Więckowsk. Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT European journal of medicinal chemistry. vol 225. 2021-11-11. PMID:34530376. |
development and crystallography-aided sar studies of multifunctional buche inhibitors and 5-ht the lack of an effective treatment makes alzheimer's disease a serious healthcare problem and a challenge for medicinal chemists. |
2021-11-11 |
2023-08-13 |
Not clear |
| Maite Solas, Debby Van Dam, Jana Janssens, U Ocariz, Yannick Vermeiren, Peter Paul De Deyn, Maria J Ramire. 5-HT Neurochemistry international. vol 150. 2021-11-11. PMID:34555475. |
5-ht even though the involvement of serotonin (5-hydroxytryptamine; 5-ht) and its receptors in alzheimer's disease (ad) is widely accepted, data on the expression and the role of 5-ht |
2021-11-11 |
2023-08-13 |
Not clear |
| Giuseppe Di Giovanni, Philippe De Deurwaerdèr. Serotonin research: Crossing scales and boundaries. Neuropharmacology. vol 181. 2021-09-23. PMID:33007358. |
modulation of serotonin transmission is considered in numerous central nervous system (cns) diseases including depression, anxiety, schizophrenia, obsessive-compulsive disorders, addiction, parkinson's disease, and alzheimer's disease. |
2021-09-23 |
2023-08-13 |
Not clear |
| Ana Salomé Correia, Armando Cardoso, Nuno Val. Highlighting Immune System and Stress in Major Depressive Disorder, Parkinson's, and Alzheimer's Diseases, with a Connection with Serotonin. International journal of molecular sciences. vol 22. issue 16. 2021-09-14. PMID:34445231. |
highlighting immune system and stress in major depressive disorder, parkinson's, and alzheimer's diseases, with a connection with serotonin. |
2021-09-14 |
2023-08-13 |
Not clear |
| Jian Lu, Chuzhao Zhang, Jianlu Lv, Xialin Zhu, Xingwu Jiang, Weiqiang Lu, Yin Lu, Zongxiang Tang, Jiaying Wang, Xu She. Antiallergic drug desloratadine as a selective antagonist of 5HT Aging cell. vol 20. issue 1. 2021-09-02. PMID:33369003. |
antiallergic drug desloratadine as a selective antagonist of 5ht alzheimer's disease (ad) is a progressively neurodegenerative disease characterized by cognitive deficits and alteration of personality and behavior. |
2021-09-02 |
2023-08-13 |
Not clear |
| Hui-Hua Li, Xiao-Yan Yao, Sheng Tao, Xue Sun, Pan-Pan Li, Xi-Xin Li, Zhu-Li Liu, Chao Re. Serotonin 2 Receptors, Agomelatine, and Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease. Behavioural neurology. vol 2021. 2021-08-18. PMID:33859767. |
serotonin 2 receptors, agomelatine, and behavioral and psychological symptoms of dementia in alzheimer's disease. |
2021-08-18 |
2023-08-13 |
Not clear |
| Arubala P Reddy, Xiangling Yin, Neha Sawant, P Hemachandra Redd. Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer's disease. Human molecular genetics. vol 30. issue 10. 2021-08-13. PMID:33615359. |
the purpose of this study is to study the neuroprotective role of selective serotonin reuptake inhibitor (ssri), citalopram, against alzheimer's disease (ad). |
2021-08-13 |
2023-08-13 |
mouse |
| Kelly Ceyzériat, Yesica Gloria, Stergios Tsartsalis, Christine Fossey, Thomas Cailly, Frédéric Fabis, Philippe Millet, Benjamin B Tournie. Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer's disease. Brain communications. vol 3. issue 2. 2021-07-22. PMID:34286270. |
alterations in dopamine system and in its connectivity with serotonin in a rat model of alzheimer's disease. |
2021-07-22 |
2023-08-13 |
rat |
| Arubala P Reddy, Neha Sawant, Hallie Morton, Sudhir Kshirsagar, Lloyd E Bunquin, Xiangling Yin, P Hemachandra Redd. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer's disease. Human molecular genetics. vol 30. issue 9. 2021-07-10. PMID:33791799. |
selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of alzheimer's disease. |
2021-07-10 |
2023-08-13 |
mouse |