| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clara Stiebing, Izabella J Jahn, Michael Schmitt, Nanda Keijzer, Robert Kleemann, Amanda J Kiliaan, Wolfgang Drexler, Rainer A Leitgeb, Jürgen Pop. Biochemical Characterization of Mouse Retina of an Alzheimer's Disease Model by Raman Spectroscopy. ACS chemical neuroscience. vol 11. issue 20. 2021-06-18. PMID:32991138. |
biochemical characterization of mouse retina of an alzheimer's disease model by raman spectroscopy. |
2021-06-18 |
2023-08-13 |
mouse |
| Clara Stiebing, Izabella J Jahn, Michael Schmitt, Nanda Keijzer, Robert Kleemann, Amanda J Kiliaan, Wolfgang Drexler, Rainer A Leitgeb, Jürgen Pop. Biochemical Characterization of Mouse Retina of an Alzheimer's Disease Model by Raman Spectroscopy. ACS chemical neuroscience. vol 11. issue 20. 2021-06-18. PMID:32991138. |
the presence of biomarkers characteristic for alzheimer's disease in the retina is a controversial topic. |
2021-06-18 |
2023-08-13 |
mouse |
| Haoshen Shi, Yosef Koronyo, Altan Rentsendorj, Giovanna C Regis, Julia Sheyn, Dieu-Trang Fuchs, Andrei A Kramerov, Alexander V Ljubimov, Oana M Dumitrascu, Anthony R Rodriguez, Ernesto Barron, David R Hinton, Keith L Black, Carol A Miller, Nazanin Mirzaei, Maya Koronyo-Hamaou. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta neuropathologica. vol 139. issue 5. 2021-06-08. PMID:32043162. |
identification of early pericyte loss and vascular amyloidosis in alzheimer's disease retina. |
2021-06-08 |
2023-08-13 |
human |
| Haoshen Shi, Yosef Koronyo, Altan Rentsendorj, Giovanna C Regis, Julia Sheyn, Dieu-Trang Fuchs, Andrei A Kramerov, Alexander V Ljubimov, Oana M Dumitrascu, Anthony R Rodriguez, Ernesto Barron, David R Hinton, Keith L Black, Carol A Miller, Nazanin Mirzaei, Maya Koronyo-Hamaou. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta neuropathologica. vol 139. issue 5. 2021-06-08. PMID:32043162. |
pericyte loss and deficient vascular platelet-derived growth factor receptor-β (pdgfrβ) signaling are prominent features of the blood-brain barrier breakdown described in alzheimer's disease (ad) that can predict cognitive decline yet have never been studied in the retina. |
2021-06-08 |
2023-08-13 |
human |
| Shawn M Barton, Eleanor To, Baxter P Rogers, Clayton Whitmore, Manjosh Uppal, Joanne A Matsubara, Wellington Pha. Inhalable Thioflavin S for the Detection of Amyloid Beta Deposits in the Retina. Molecules (Basel, Switzerland). vol 26. issue 4. 2021-05-11. PMID:33562625. |
we present an integrated delivery technology herein employing the aerosolized method to repurpose thioflavin s for imaging amyloid beta (abeta) deposits in the retina as a surrogate of abeta in the brain for early detection of alzheimer's disease. |
2021-05-11 |
2023-08-13 |
mouse |
| Nina Schultz, Elin Byman, Malin Wennströ. Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884473. |
previous studies have used immunohistology to demonstrate alzheimer's disease (ad) characteristic accumulation of amyloid-β (aβ) in the retina of ad patients, a finding indicating retina examination as a potential diagnostic tool for ad pathology. |
2021-05-10 |
2023-08-13 |
Not clear |
| Sumana R Chintapaludi, Asli Uyar, Harriet M Jackson, Casey J Acklin, Xulong Wang, Michael Sasner, Gregory W Carter, Gareth R Howel. Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling. Journal of Alzheimer's disease : JAD. vol 73. issue 4. 2021-05-06. PMID:31929156. |
staging alzheimer's disease in the brain and retina of b6.app/ps1 mice by transcriptional profiling. |
2021-05-06 |
2023-08-13 |
mouse |
| Liang Wang, Xiaobo Ma. Role of Retinal Amyloid-β in Neurodegenerative Diseases: Overlapping Mechanisms and Emerging Clinical Applications. International journal of molecular sciences. vol 22. issue 5. 2021-04-19. PMID:33653000. |
amyloid-β (aβ) accumulations have been identified in the retina for neurodegeneration-associated disorders like alzheimer's disease (ad), glaucoma, and age-related macular degeneration (amd). |
2021-04-19 |
2023-08-13 |
Not clear |
| Zhongyong Shi, Xinyi Cao, Jingxiao Hu, Lijuan Jiang, Xinchun Mei, Hailin Zheng, Yupeng Chen, Meijuan Wang, Jing Cao, Wei Li, Ting Li, Chunbo Li, Yuan She. Retinal nerve fiber layer thickness is associated with hippocampus and lingual gyrus volumes in nondemented older adults. Progress in neuro-psychopharmacology & biological psychiatry. vol 99. 2021-03-31. PMID:31765713. |
abnormal retina structures, such as thinner retinal nerve fiber layer (rnfl), have been frequently reported in patients with alzheimer's disease (ad). |
2021-03-31 |
2023-08-13 |
Not clear |
| Julius Baya Mdzomba, Sandrine Joly, Léa Rodriguez, Ali Dirani, Patricia Lassiaz, Francine Behar-Cohen, Vincent Perne. Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury. Cell death & disease. vol 11. issue 2. 2021-03-09. PMID:32029703. |
n-methyl-d-aspartate (nmda)-induced neuronal cell death is involved in a large spectrum of diseases affecting the brain and the retina such as alzheimer's disease and diabetic retinopathy. |
2021-03-09 |
2023-08-13 |
mouse |
| Roxana O Carare, Roxana Aldea, Nivedita Agarwal, Brian J Bacskai, Ingo Bechman, Delphine Boche, Guojun Bu, Diederik Bulters, Alt Clemens, Scott E Counts, Mony de Leon, Per K Eide, Silvia Fossati, Steven M Greenberg, Edith Hamel, Cheryl A Hawkes, Maya Koronyo-Hamaoui, Atticus H Hainsworth, David Holtzman, Masafumi Ihara, Angela Jefferson, Raj N Kalaria, Christopher M Kipps, Katja M Kanninen, Ville Leinonen, JoAnne McLaurin, Scott Miners, Tarja Malm, James A R Nicoll, Fabrizio Piazza, Gesine Paul, Steven M Rich, Satoshi Saito, Andy Shih, Henrieta Scholtzova, Heather Snyder, Peter Snyder, Finnbogi Rutur Thormodsson, Susanne J van Veluw, Roy O Weller, David J Werring, Donna Wilcock, Mark R Wilson, Berislav V Zlokovic, Ajay Verm. Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-03-04. PMID:32775596. |
clearance of interstitial fluid (isf) and csf (clic) group-part of vascular professional interest area (pia): cerebrovascular disease and the failure of elimination of amyloid-β from the brain and retina with age and alzheimer's disease-opportunities for therapy. |
2021-03-04 |
2023-08-13 |
Not clear |
| David Bissig, Clarice G Zhou, Vy Le, Jacqueline T Bernar. Optical coherence tomography reveals light-dependent retinal responses in Alzheimer's disease. NeuroImage. vol 219. 2021-02-23. PMID:32512126. |
spectral-domain optical coherence tomography (sd-oct) is an accessible clinical tool for measuring structural changes to the retina, and increasingly as a biomarker for brain-predominant neurodegenerative diseases like alzheimer's. |
2021-02-23 |
2023-08-13 |
Not clear |
| Elena Salobrar-Garcia, Carmen Méndez-Hernández, Rosa de Hoz, Ana I Ramírez, Inés López-Cuenca, José A Fernández-Albarral, Pilar Rojas, Surina Wang, Julián García-Feijoo, Pedro Gil, Juan J Salazar, José M Ramíre. Ocular Vascular Changes in Mild Alzheimer's Disease Patients: Foveal Avascular Zone, Choroidal Thickness, and ONH Hemoglobin Analysis. Journal of personalized medicine. vol 10. issue 4. 2020-12-26. PMID:33203157. |
in patients with alzheimer's disease, thinning of the choroid and the retina has been shown. |
2020-12-26 |
2023-08-13 |
Not clear |
| Refika Hande Karakahya, Tuba Şaziye Özca. Salvage of the retinal ganglion cells in transition phase in Alzheimer's disease with topical coenzyme Q10: is it possible? Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 258. issue 2. 2020-12-01. PMID:31781880. |
the evaluation of the short-term effect of topically applied coenzyme q10 (coq10) on retina and choroid in alzheimer's disease (ad) was aimed in this study. |
2020-12-01 |
2023-08-13 |
Not clear |
| Jonah Doustar, Altan Rentsendorj, Tania Torbati, Giovanna C Regis, Dieu-Trang Fuchs, Julia Sheyn, Nazanin Mirzaei, Stuart L Graham, Prediman K Shah, Mitra Mastali, Jennifer E Van Eyk, Keith L Black, Vivek K Gupta, Mehdi Mirzaei, Yosef Koronyo, Maya Koronyo-Hamaou. Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models. Aging cell. 2020-11-29. PMID:33090673. |
despite growing evidence for the characteristic signs of alzheimer's disease (ad) in the neurosensory retina, our understanding of retina-brain relationships, especially at advanced disease stages and in response to therapy, is lacking. |
2020-11-29 |
2023-08-13 |
mouse |
| Nazanin Mirzaei, Haoshen Shi, Mia Oviatt, Jonah Doustar, Altan Rentsendorj, Dieu-Trang Fuchs, Julia Sheyn, Keith L Black, Yosef Koronyo, Maya Koronyo-Hamaou. Alzheimer's Retinopathy: Seeing Disease in the Eyes. Frontiers in neuroscience. vol 14. 2020-11-14. PMID:33041751. |
the neurosensory retina emerges as a prominent site of alzheimer's disease (ad) pathology. |
2020-11-14 |
2023-08-13 |
Not clear |
| Elena Salobrar-García, Ana C Rodrigues-Neves, Ana I Ramírez, Rosa de Hoz, José A Fernández-Albarral, Inés López-Cuenca, José M Ramírez, António F Ambrósio, Juan J Salaza. Microglial Activation in the Retina of a Triple-Transgenic Alzheimer's Disease Mouse Model (3xTg-AD). International journal of molecular sciences. vol 21. issue 3. 2020-11-03. PMID:32012676. |
microglial activation in the retina of a triple-transgenic alzheimer's disease mouse model (3xtg-ad). |
2020-11-03 |
2023-08-13 |
mouse |
| Carolina Alves, Lília Jorge, Nádia Canário, Beatriz Santiago, Isabel Santana, João Castelhano, António Francisco Ambrósio, Rui Bernardes, Miguel Castelo-Branc. Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 70. issue 3. 2020-10-09. PMID:31282416. |
this study aims to investigate the relationship between structural changes in the retina and white matter in the brain, in early alzheimer's disease (ad). |
2020-10-09 |
2023-08-13 |
Not clear |
| James Polans, Brenton Keller, Oscar M Carrasco-Zevallos, Francesco LaRocca, Elijah Cole, Heather E Whitson, Eleonora M Lad, Sina Farsiu, Joseph A Izat. Wide-field retinal optical coherence tomography with wavefront sensorless adaptive optics for enhanced imaging of targeted regions. Biomedical optics express. vol 8. issue 1. 2020-10-01. PMID:28101398. |
this work suggests that the proposed combination of wf-oct and wsao may find applications in the diagnosis and treatment of ocular, and potentially neurodegenerative, diseases of the peripheral retina, including diabetes and alzheimer's disease. |
2020-10-01 |
2023-08-13 |
human |
| Ana I Ramirez, Rosa de Hoz, Elena Salobrar-Garcia, Juan J Salazar, Blanca Rojas, Daniel Ajoy, Inés López-Cuenca, Pilar Rojas, Alberto Triviño, José M Ramíre. The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma. Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:28729832. |
the brain and retina are affected in several neurodegenerative diseases, including alzheimer's disease (ad), parkinson's disease (pd), and glaucoma. |
2020-10-01 |
2023-08-13 |
Not clear |