| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Zhang, Feng Gao, Yuqian Ma, Tian Xue, Yong She. Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease. iScience. vol 24. issue 11. 2021-11-23. PMID:34805789. |
research in patients with alzheimer's disease (ad) and in ad transgenic mice reports that accumulated amyloid-β (aβ) plaques in the retina are toxic to retinal neurons. |
2021-11-23 |
2023-08-13 |
mouse |
| Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano, Giuseppina Amador. Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33750467. |
retina and optic nerve are sites of extra-cerebral manifestations of alzheimer's disease (ad). |
2021-11-18 |
2023-08-13 |
mouse |
| Ryan J Bevan, Tim R Hughes, Pete A Williams, Mark A Good, B Paul Morgan, James E Morga. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta neuropathologica communications. vol 8. issue 1. 2021-11-09. PMID:33287900. |
retinal ganglion cells, the output neurons of the retina, are vulnerable to damage in neurodegenerative diseases and are a potential opportunity for non-invasive clinical diagnosis and monitoring of alzheimer's progression. |
2021-11-09 |
2023-08-13 |
mouse |
| Chiara Burgaletto, Chiara Bianca Maria Platania, Giulia Di Benedetto, Antonio Munafò, Giovanni Giurdanella, Concetta Federico, Rosario Caltabiano, Salvatore Saccone, Federica Conti, Renato Bernardini, Claudio Bucolo, Giuseppina Cantarell. Targeting the miRNA-155/TNFSF10 network restrains inflammatory response in the retina in a mouse model of Alzheimer's disease. Cell death & disease. vol 12. issue 10. 2021-11-09. PMID:34611142. |
targeting the mirna-155/tnfsf10 network restrains inflammatory response in the retina in a mouse model of alzheimer's disease. |
2021-11-09 |
2023-08-13 |
mouse |
| E S Simons, M A Smith, C M Dengler-Crish, S D Cris. Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta. Neurobiology of disease. vol 147. 2021-11-01. PMID:33122075. |
pathological accumulations of amyloid-beta (aβ) peptide are found in retina early in alzheimer's disease, yet its effects on retinal neuronal structure remain unknown. |
2021-11-01 |
2023-08-13 |
Not clear |
| Soyoung Choi, Li Guo, Maria Francesca Cordeir. Retinal and Brain Microglia in Multiple Sclerosis and Neurodegeneration. Cells. vol 10. issue 6. 2021-11-01. PMID:34203793. |
in this review, we describe characteristics of cns microglia, including those in the retina, with a focus on their morphology, activation states and function in health, ageing, ms and other neurodegenerative diseases such as alzheimer's disease, parkinson's disease, glaucoma and retinitis pigmentosa, to highlight their activity in disease. |
2021-11-01 |
2023-08-13 |
Not clear |
| Jennifer Ngolab, Michael Donohue, Alison Belsha, Jennifer Salazar, Paula Cohen, Sandhya Jaiswal, Veasna Tan, Devon Gessert, Shaina Korouri, Neelum T Aggarwal, Jessica Alber, Ken Johnson, Gregory Jicha, Christopher van Dyck, James Lah, Stephen Salloway, Reisa A Sperling, Paul S Aisen, Michael S Rafii, Robert A Rissma. Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-10-22. PMID:34430703. |
the ability to access the retina through imaging techniques opens the possibility for non-invasive evaluation of alzheimer's disease (ad) pathology. |
2021-10-22 |
2023-08-13 |
Not clear |
| Savannah A Lynn, David A Johnston, Jenny A Scott, Rosie Munday, Roshni S Desai, Eloise Keeling, Ruaridh Weaterton, Alexander Simpson, Dillon Davis, Thomas Freeman, David S Chatelet, Anton Page, Angela J Cree, Helena Lee, Tracey A Newman, Andrew J Lotery, J Arjuna Ratnayak. Oligomeric Aβ Cells. vol 10. issue 2. 2021-10-18. PMID:33671133. |
oligomeric aβ alzheimer's disease-associated amyloid beta (aβ) proteins accumulate in the outer retina with increasing age and in eyes of age-related macular degeneration (amd) patients. |
2021-10-18 |
2023-08-13 |
mouse |
| Haoshen Shi, Yosef Koronyo, Altan Rentsendorj, Dieu-Trang Fuchs, Julia Sheyn, Keith L Black, Nazanin Mirzaei, Maya Koronyo-Hamaou. Retinal Vasculopathy in Alzheimer's Disease. Frontiers in neuroscience. vol 15. 2021-10-12. PMID:34630020. |
the retina has been increasingly investigated as a site of alzheimer's disease (ad) manifestation for over a decade. |
2021-10-12 |
2023-08-13 |
Not clear |
| Jeremiah K H Lim, Qiao-Xin Li, Tim Ryan, Phillip Bedggood, Andrew Metha, Algis J Vingrys, Bang V Bui, Christine T O Nguye. Retinal hyperspectral imaging in the 5xFAD mouse model of Alzheimer's disease. Scientific reports. vol 11. issue 1. 2021-10-11. PMID:33737550. |
hyperspectral imaging of the retina has recently been posited as a potentially useful form of spectroscopy of amyloid-beta (aβ) protein in the eyes of those with alzheimer's disease (ad). |
2021-10-11 |
2023-08-13 |
mouse |
| Lília Jorge, Nádia Canário, Ricardo Martins, Beatriz Santiago, Isabel Santana, Hugo Quental, Francisco Ambrósio, Rui Bernardes, Miguel Castelo-Branc. The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid Neural plasticity. vol 2020. 2021-09-13. PMID:33014034. |
the retinal inner plexiform synaptic layer mirrors grey matter thickness of primary visual cortex with increased amyloid the retina may serve as putative window into neuropathology of synaptic loss in alzheimer's disease (ad). |
2021-09-13 |
2023-08-13 |
Not clear |
| Xi Mei, Mengxiang Yang, Lina Zhu, Qi Zhou, Xingxing Li, Zhongming Chen, Chenjun Zo. Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease. Behavioural neurology. vol 2020. 2021-08-18. PMID:33029254. |
retina abnormalities are related to cognitive disorders in patients with alzheimer's disease (ad). |
2021-08-18 |
2023-08-13 |
mouse |
| Jianqiao Tian, Glenn Smith, Han Guo, Boya Liu, Zehua Pan, Zijie Wang, Shuangyu Xiong, Ruogu Fan. Modular machine learning for Alzheimer's disease classification from retinal vasculature. Scientific reports. vol 11. issue 1. 2021-08-09. PMID:33420208. |
in this work, we took the initiative to evaluate the retina, especially the retinal vasculature, as an alternative for conducting screenings for dementia patients caused by alzheimer's disease. |
2021-08-09 |
2023-08-13 |
Not clear |
| Wei Yan Ng, Carol Y Cheung, Dan Milea, Daniel Shu Wei Tin. Artificial intelligence and machine learning for Alzheimer's disease: let's not forget about the retina. The British journal of ophthalmology. vol 105. issue 5. 2021-07-28. PMID:33495160. |
artificial intelligence and machine learning for alzheimer's disease: let's not forget about the retina. |
2021-07-28 |
2023-08-13 |
Not clear |
| Anna Luna Mølgaard Tams, Berta Sanz-Morello, Emil Winther Westi, Zaynab Ahmad Mouhammad, Jens Velde Andersen, Kristine Karla Freude, Rupali Vohra, Jens Hannibal, Blanca Irene Aldana, Miriam Kolk. Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease. Cellular and molecular neurobiology. 2021-07-14. PMID:34259962. |
decreased glucose metabolism and glutamine synthesis in the retina of a transgenic mouse model of alzheimer's disease. |
2021-07-14 |
2023-08-13 |
mouse |
| Ying Zhang, Yanjiang Wang, Ce Shi, Meixiao Shen, Fan L. Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer's disease. Translational neurodegeneration. vol 10. issue 1. 2021-07-13. PMID:33517891. |
advances in retina imaging as potential biomarkers for early diagnosis of alzheimer's disease. |
2021-07-13 |
2023-08-13 |
Not clear |
| Ana Catarina Rodrigues-Neves, Rafael Carecho, Sónia Catarina Correia, Cristina Carvalho, Elisa Julião Campos, Filipa Isabel Baptista, Paula Isabel Moreira, António Francisco Ambrósi. Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease. Molecular neurobiology. vol 58. issue 7. 2021-07-06. PMID:33606195. |
retina and brain display early and differential molecular and cellular changes in the 3xtg-ad mouse model of alzheimer's disease. |
2021-07-06 |
2023-08-13 |
mouse |
| Stephan Szegedi, Peter Dal-Bianco, Elisabeth Stögmann, Tatjana Traub-Weidinger, Michael Rainer, Andreas Masching, Doreen Schmidl, René M Werkmeister, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfe. Anatomical and functional changes in the retina in patients with Alzheimer's disease and mild cognitive impairment. Acta ophthalmologica. vol 98. issue 7. 2021-07-05. PMID:32212415. |
anatomical and functional changes in the retina in patients with alzheimer's disease and mild cognitive impairment. |
2021-07-05 |
2023-08-13 |
Not clear |
| Stephan Szegedi, Peter Dal-Bianco, Elisabeth Stögmann, Tatjana Traub-Weidinger, Michael Rainer, Andreas Masching, Doreen Schmidl, René M Werkmeister, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfe. Anatomical and functional changes in the retina in patients with Alzheimer's disease and mild cognitive impairment. Acta ophthalmologica. vol 98. issue 7. 2021-07-05. PMID:32212415. |
there is evidence that mild cognitive impairment (mci) or alzheimer's disease (ad) is accompanied by alterations in the retina. |
2021-07-05 |
2023-08-13 |
Not clear |
| Kevin J Cao, John H Kim, Heike Kroeger, Patricia M Gaffney, Jonathan H Lin, Christina J Sigurdson, Jerry Yan. ARCAM-1 Facilitates Fluorescence Detection of Amyloid-Containing Deposits in the Retina. Translational vision science & technology. vol 10. issue 7. 2021-06-28. PMID:34096989. |
to investigate the use of an amyloid-targeting fluorescent probe, arcam-1, to identify amyloid-containing deposits in the retina of a transgenic mouse model of alzheimer's disease (ad) and in human postmortem ad patients. |
2021-06-28 |
2023-08-13 |
mouse |