| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bingying Zhao, Yibing Yan, Xingqi Wu, Zhi Geng, Yue Wu, Guixian Xiao, Lu Wang, Shanshan Zhou, Ling Wei, Kai Wang, Rongfeng Lia. The correlation of retinal neurodegeneration and brain degeneration in patients with Alzheimer's disease using optical coherence tomography angiography and MRI. Frontiers in aging neuroscience. vol 15. 2023-05-01. PMID:37122375. |
pathological changes in alzheimer's disease can cause retina and optic nerve degeneration. |
2023-05-01 |
2023-08-14 |
Not clear |
| Xiaoyu Ma, Zengmai Xie, Huan Wang, Zhongping Tian, Yanlong Bi, Yunxia Li, Li Zhan. A cross-sectional study of retinal vessel changes based on optical coherence tomography angiography in Alzheimer's disease and mild cognitive impairment. Frontiers in aging neuroscience. vol 15. 2023-04-28. PMID:37113575. |
the involvement of retina and its vasculature has been recently described in alzheimer's disease (ad). |
2023-04-28 |
2023-08-14 |
Not clear |
| Suman Adhikari, Yuchuan Qiao, Maxwell Singer, Abhay Sagare, Xuejuan Jiang, Yonggang Shi, John M Ringman, Amir H Kashan. Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-27. PMID:37102308. |
retinotopic degeneration of the retina and optic tracts in autosomal dominant alzheimer's disease. |
2023-04-27 |
2023-08-14 |
human |
| Heba Ahmed Gaber, Eman Mohamed Aly, Eman Saad Mohamed, Marwa Elfouly, Mona Salah Talaat, El-Sayed Mahmoud El-Saye. Prognosis of Biomarker of Alzheimer's Disease in the Function of the Retina and Secondary Molecular Structure Variation of the Retina and Brain. International journal of Alzheimer's disease. vol 2023. 2023-04-10. PMID:37035098. |
prognosis of biomarker of alzheimer's disease in the function of the retina and secondary molecular structure variation of the retina and brain. |
2023-04-10 |
2023-08-14 |
rat |
| Ashleigh Barrett-Young, Wickliffe C Abraham, Carol Y Cheung, Jesse Gale, Sean Hogan, David Ireland, Ross Keenan, Annchen R Knodt, Tracy R Melzer, Terrie E Moffitt, Sandhya Ramrakha, Yih Chung Tham, Graham A Wilson, Tien Yin Wong, Ahmad R Hariri, Richie Poulto. Associations Between Thinner Retinal Neuronal Layers and Suboptimal Brain Structural Integrity in a Middle-Aged Cohort. Eye and brain. vol 15. 2023-03-20. PMID:36936476. |
the retina has potential as a biomarker of brain health and alzheimer's disease (ad) because it is the only part of the central nervous system which can be easily imaged and has advantages over brain imaging technologies. |
2023-03-20 |
2023-08-14 |
Not clear |
| Xiaoli Hao, Weiwei Zhang, Bin Jiao, Qijie Yang, Xinyue Zhang, Ruiting Chen, Xin Wang, Xuewen Xiao, Yuan Zhu, Weihua Liao, Dongcui Wang, Lu She. Correlation between retinal structure and brain multimodal magnetic resonance imaging in patients with Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-03-13. PMID:36909943. |
the retina imaging and brain magnetic resonance imaging (mri) can both reflect early changes in alzheimer's disease (ad) and may serve as potential biomarker for early diagnosis, but their correlation and the internal mechanism of retinal structural changes remain unclear. |
2023-03-13 |
2023-08-14 |
Not clear |
| Benjamin J Kim, Murray Grossman, Tomas S Aleman, Delu Song, Katheryn A Q Cousins, Corey T McMillan, Adrienne Saludades, Yinxi Yu, Edward B Lee, David Wolk, Vivianna M Van Deerlin, Leslie M Shaw, Gui-Shuang Ying, David J Irwi. Retinal photoreceptor layer thickness has disease specificity and distinguishes predicted FTLD-Tau from biomarker-determined Alzheimer's disease. Neurobiology of aging. vol 125. 2023-03-01. PMID:36857870. |
while alzheimer's disease (ad) is associated with inner retina thinning (retinal nerve fiber layer and ganglion cell layer), we have observed photoreceptor outer nuclear layer (onl) thinning in patients with frontotemporal lobar degeneration tauopathy (ftld-tau) compared to normal controls. |
2023-03-01 |
2023-08-14 |
Not clear |
| Yosef Koronyo, Altan Rentsendorj, Nazanin Mirzaei, Giovanna C Regis, Julia Sheyn, Haoshen Shi, Ernesto Barron, Galen Cook-Wiens, Anthony R Rodriguez, Rodrigo Medeiros, Joao A Paulo, Veer B Gupta, Andrei A Kramerov, Alexander V Ljubimov, Jennifer E Van Eyk, Stuart L Graham, Vivek K Gupta, John M Ringman, David R Hinton, Carol A Miller, Keith L Black, Antonino Cattaneo, Giovanni Meli, Mehdi Mirzaei, Dieu-Trang Fuchs, Maya Koronyo-Hamaou. Retinal pathological features and proteome signatures of Alzheimer's disease. Acta neuropathologica. 2023-02-11. PMID:36773106. |
alzheimer's disease (ad) pathologies were discovered in the accessible neurosensory retina. |
2023-02-11 |
2023-08-14 |
human |
| Mira Y Tang, Marian S Blazes, Cecilia S Le. Imaging Amyloid and Tau in the Retina: Current Research and Future Directions. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2023-01-27. PMID:36705970. |
the retina is a key focus in the search for biomarkers of alzheimer's disease (ad) because of its accessibility and shared development with the brain. |
2023-01-27 |
2023-08-14 |
Not clear |
| L Arouche-Delaperche, S Cadoni, C Joffrois, G Labernede, M Valet, Q César, J Dégardin, S Girardon, C Gabriel, S Krantic, S Picau. Dysfunction of the glutamatergic photoreceptor synapse in the P301S mouse model of tauopathy. Acta neuropathologica communications. vol 11. issue 1. 2023-01-11. PMID:36631898. |
this dysfunction of retinal glutamatergic synapses suggests a novel interpretation for visual deficits in tauopathies and it highlights the potential value of the retina for the diagnostic assessment and the evaluation of therapies in alzheimer's disease and other tauopathies. |
2023-01-11 |
2023-08-14 |
mouse |
| Frederique J Hart de Ruyter, Tjado H J Morrema, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Baayla D C Boon, Dietmar R Thal, Annemieke J Rozemuller, Frank D Verbraak, Femke H Bouwman, Jeroen J M Hoozeman. Correction to: Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies. Acta neuropathologica. 2022-12-23. PMID:36562817. |
correction to: phosphorylated tau in the retina correlates with tau pathology in the brain in alzheimer's disease and primary tauopathies. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yunkwon Nam, Sujin Kim, Jieun Kim, Hyang-Sook Hoe, Minho Moo. Mesoscopic Mapping of Visual Pathway in a Female 5XFAD Mouse Model of Alzheimer's Disease. Cells. vol 11. issue 23. 2022-12-11. PMID:36497159. |
amyloid-β (aβ) deposition and aβ-induced neurodegeneration appear in the retina and retinorecipient areas in the early stages of alzheimer's disease (ad). |
2022-12-11 |
2023-08-14 |
mouse |
| Sunu Mathew, Darrell WuDunn, Devin D Mackay, Aaron Vosmeier, Eileen F Tallman, Rachael Deardorff, Alon Harris, Martin R Farlow, Jared R Brosch, Sujuan Gao, Liana G Apostolova, Andrew J Saykin, Shannon L Risache. Association of Brain Volume and Retinal Thickness in the Early Stages of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-12-11. PMID:36502316. |
the eye has been considered a 'window to the brain,' and several neurological diseases including neurodegenerative conditions like alzheimer's disease (ad) also show changes in the retina. |
2022-12-11 |
2023-08-14 |
Not clear |
| Frederique J Hart de Ruyter, Tjado H J Morrema, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Baayla D C Boon, Dietmar R Thal, Annemieke J Rozemuller, Frank D Verbraak, Femke H Bouwman, Jeroen J M Hoozeman. Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies. Acta neuropathologica. 2022-12-08. PMID:36480077. |
phosphorylated tau in the retina correlates with tau pathology in the brain in alzheimer's disease and primary tauopathies. |
2022-12-08 |
2023-08-14 |
Not clear |
| Bijorn Omar Balzamino, Graziana Esposito, Ramona Marino, Pietro Calissano, Valentina Latina, Giuseppina Amadoro, Flavio Keller, Andrea Cacciamani, Alessandra Micer. Morphological and biomolecular targets in retina and vitreous from Reelin-deficient mice (Reeler): Potential implications for age-related macular degeneration in Alzheimer's dementia. Frontiers in aging neuroscience. vol 14. 2022-12-05. PMID:36466614. |
morphological and biomolecular targets in retina and vitreous from reelin-deficient mice (reeler): potential implications for age-related macular degeneration in alzheimer's dementia. |
2022-12-05 |
2023-08-14 |
mouse |
| Qinyuan Alis Xu, Pierre Boerkoel, Veronica Hirsch-Reinshagen, Ian R Mackenzie, Ging-Yuek Robin Hsiung, Geoffrey Charm, Elliott F To, Alice Q Liu, Katerina Schwab, Kailun Jiang, Marinko Sarunic, Mirza Faisal Beg, Wellington Pham, Jing Cui, Eleanor To, Sieun Lee, Joanne A Matsubar. Müller cell degeneration and microglial dysfunction in the Alzheimer's retina. Acta neuropathologica communications. vol 10. issue 1. 2022-10-05. PMID:36199154. |
müller cell degeneration and microglial dysfunction in the alzheimer's retina. |
2022-10-05 |
2023-08-14 |
Not clear |
| Qinyuan Alis Xu, Pierre Boerkoel, Veronica Hirsch-Reinshagen, Ian R Mackenzie, Ging-Yuek Robin Hsiung, Geoffrey Charm, Elliott F To, Alice Q Liu, Katerina Schwab, Kailun Jiang, Marinko Sarunic, Mirza Faisal Beg, Wellington Pham, Jing Cui, Eleanor To, Sieun Lee, Joanne A Matsubar. Müller cell degeneration and microglial dysfunction in the Alzheimer's retina. Acta neuropathologica communications. vol 10. issue 1. 2022-10-05. PMID:36199154. |
amyloid beta (aβ) deposits in the retina of the alzheimer's disease (ad) eye may provide a useful diagnostic biomarker for ad. |
2022-10-05 |
2023-08-14 |
Not clear |
| Carol Y Cheung, An Ran Ran, Shujun Wang, Victor T T Chan, Kaiser Sham, Saima Hilal, Narayanaswamy Venketasubramanian, Ching-Yu Cheng, Charumathi Sabanayagam, Yih Chung Tham, Leopold Schmetterer, Gareth J McKay, Michael A Williams, Adrian Wong, Lisa W C Au, Zhihui Lu, Jason C Yam, Clement C Tham, John J Chen, Oana M Dumitrascu, Pheng-Ann Heng, Timothy C Y Kwok, Vincent C T Mok, Dan Milea, Christopher Li-Hsian Chen, Tien Yin Won. A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study. The Lancet. Digital health. 2022-10-03. PMID:36192349. |
we aimed to develop a deep learning algorithm that could use retinal photographs alone, which is the most common method of non-invasive imaging the retina to detect alzheimer's disease-dementia. |
2022-10-03 |
2023-08-14 |
Not clear |
| Xin Wang, Yaqin Wang, Hui Liu, Xiangyu Zhu, Xiaoli Hao, Yuan Zhu, Bei Xu, Sizhe Zhang, Xiaoliang Jia, Ling Weng, Xinxin Liao, Yafang Zhou, Beisha Tang, Rongchang Zhao, Bin Jiao, Lu She. Macular Microvascular Density as a Diagnostic Biomarker for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-09-12. PMID:36093699. |
some previous studies showed abnormal pathological and vascular changes in the retina of patients with alzheimer's disease (ad). |
2022-09-12 |
2023-08-14 |
Not clear |
| Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R Davis, Jered W Wilson, Milica A Margeta, Kristen M Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L Graham, Vivek K Gupta, Keith L Black, Mehdi Mirzaei, Oleg Butovsky, Maya Koronyo-Hamaou. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3 Acta neuropathologica communications. vol 10. issue 1. 2022-09-08. PMID:36076283. |
despite growing interest in studying manifestations of alzheimer's disease (ad) in the retina, a cns organ accessible to noninvasive high-resolution imaging, to date mgnd microglia have not been studied in the ad retina. |
2022-09-08 |
2023-08-14 |
Not clear |