| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Arai, M L Schmidt, V M Lee, H I Hurtig, B D Greenberg, C H Adler, J Q Trojanowsk. Epitope analysis of senile plaque components in the hippocampus of patients with Parkinson's disease. Neurology. vol 42. issue 7. 1992-08-06. PMID:1377804. |
we conducted an epitope analysis of senile plaque (sp) proteins on hippocampal sps in patients with parkinson's disease (pd), using a library of antibodies to proteins implicated in the genesis of hippocampal sps in alzheimer's disease (ad). |
1992-08-06 |
2023-08-11 |
human |
| E Lamperti, D Cocchi, E A Parati, T Caraceni, E E Mülle. Growth hormone responses to cholinergically active drugs in patients with dementia of the Alzheimer type. Alzheimer disease and associated disorders. vol 6. issue 1. 1992-07-21. PMID:1605943. |
patients with dementia of the alzheimer type (dat) reportedly have reduced concentrations and function of some brain messengers, particularly acetylcholine and somatostatin, not only in the cerebral cortex, but also in subcortical structures, e.g., the hippocampus and the hypothalamus. |
1992-07-21 |
2023-08-11 |
human |
| M Ikeda, D Dewar, J McCulloc. Selective reduction of [125I]apamin binding sites in Alzheimer hippocampus: a quantitative autoradiographic study. Brain research. vol 567. issue 1. 1992-07-01. PMID:1667746. |
selective reduction of [125i]apamin binding sites in alzheimer hippocampus: a quantitative autoradiographic study. |
1992-07-01 |
2023-08-11 |
human |
| M Ikeda, D Dewar, J McCulloc. Selective reduction of [125I]apamin binding sites in Alzheimer hippocampus: a quantitative autoradiographic study. Brain research. vol 567. issue 1. 1992-07-01. PMID:1667746. |
[125i]apamin binding sites were examined using quantitative autoradiography in the hippocampus of 9 patients with alzheimer's disease and 8 age-matched controls. |
1992-07-01 |
2023-08-11 |
human |
| P Zhang, E C Hirsch, P Damier, C Duyckaerts, F Javoy-Agi. c-fos protein-like immunoreactivity: distribution in the human brain and over-expression in the hippocampus of patients with Alzheimer's disease. Neuroscience. vol 46. issue 1. 1992-06-30. PMID:1594107. |
c-fos protein-like immunoreactivity: distribution in the human brain and over-expression in the hippocampus of patients with alzheimer's disease. |
1992-06-30 |
2023-08-11 |
human |
| P Zhang, E C Hirsch, P Damier, C Duyckaerts, F Javoy-Agi. c-fos protein-like immunoreactivity: distribution in the human brain and over-expression in the hippocampus of patients with Alzheimer's disease. Neuroscience. vol 46. issue 1. 1992-06-30. PMID:1594107. |
in order to analyse the effect of brain injury on c-fos expression, the characteristics of the immunostaining were analysed in the hippocampus of patients deceased with alzheimer's disease known to be associated with a preferential vulnerability of the pyramidal neurons. |
1992-06-30 |
2023-08-11 |
human |
| M K Sutherland, M J Somerville, L K Yoong, C Bergeron, M R Haussler, D R McLachla. Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels. Brain research. Molecular brain research. vol 13. issue 3. 1992-06-29. PMID:1317496. |
reduction of vitamin d hormone receptor mrna levels in alzheimer as compared to huntington hippocampus: correlation with calbindin-28k mrna levels. |
1992-06-29 |
2023-08-11 |
Not clear |
| S J Kirsch, R W Jacobs, L L Butcher, J Beatt. Prolongation of magnetic resonance T2 time in hippocampus of human patients marks the presence and severity of Alzheimer's disease. Neuroscience letters. vol 134. issue 2. 1992-06-25. PMID:1589144. |
prolongation of magnetic resonance t2 time in hippocampus of human patients marks the presence and severity of alzheimer's disease. |
1992-06-25 |
2023-08-11 |
human |
| M Ikeda, D Dewar, J McCulloc. Preservation of [125I]galanin binding sites despite loss of cholinergic neurones to the hippocampus in Alzheimer's disease. Brain research. vol 568. issue 1-2. 1992-06-23. PMID:1726069. |
preservation of [125i]galanin binding sites despite loss of cholinergic neurones to the hippocampus in alzheimer's disease. |
1992-06-23 |
2023-08-11 |
human |
| M Ikeda, D Dewar, J McCulloc. Preservation of [125I]galanin binding sites despite loss of cholinergic neurones to the hippocampus in Alzheimer's disease. Brain research. vol 568. issue 1-2. 1992-06-23. PMID:1726069. |
[125i]galanin binding sites were examined in the hippocampal region of patients with alzheimer's disease (ad) and age-matched control subjects using quantitative autoradiography. |
1992-06-23 |
2023-08-11 |
human |
| A Sudilovsky, B Turnbull, S H Croog, T Croo. Angiotensin converting enzyme and memory: preclinical and clinical data. International journal of neurology. vol 21-22. 1992-06-17. PMID:2856549. |
the activity of the enzyme has been found to be significantly increased in the caudate nucleus, the frontal cortex, parahyppocampal gyrus, and medial hippocampus of patients dying with alzheimer's disease when compared to age-matched controls (arregui et al, 1982). |
1992-06-17 |
2023-08-11 |
rat |
| G Ransmayr, P Cervera, E C Hirsch, W Berger, W Fischer, Y Agi. Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1374541. |
alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? |
1992-06-05 |
2023-08-11 |
human |
| G Ransmayr, P Cervera, E C Hirsch, W Berger, W Fischer, Y Agi. Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1374541. |
consistent findings in the hippocampi of patients with alzheimer's disease are the presence of neurofibrillary tangles in pyramidal neurons and the loss of choline acetyltransferase activity due to degeneration of hippocampal cholinergic terminals. |
1992-06-05 |
2023-08-11 |
human |
| G Ransmayr, P Cervera, E C Hirsch, W Berger, W Fischer, Y Agi. Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1374541. |
the present study sought to clarify, in the brains of five patients with alzheimer's disease and four controls, whether the loss of cholinergic terminals in the hippocampal stratum pyramidale in alzheimer's disease is related to degenerative changes in hippocampal pyramidal cells. |
1992-06-05 |
2023-08-11 |
human |
| G Ransmayr, P Cervera, E C Hirsch, W Berger, W Fischer, Y Agi. Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1374541. |
in the group of alzheimer patients, the densities of cholinergic terminals were homogeneously diminished in the three hippocampal subregions in comparison with the controls (32-33%). |
1992-06-05 |
2023-08-11 |
human |
| G Ransmayr, P Cervera, E C Hirsch, W Berger, W Fischer, Y Agi. Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology? Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1374541. |
these findings suggest that there is no relationship between the loss of cholinergic terminals and the degeneration of pyramidal cells in the hippocampus of patients with alzheimer's disease. |
1992-06-05 |
2023-08-11 |
human |
| Y Gache, J Guilleminot, F Ricolfi, G Theiss, J Nune. A tau-related protein of 130 kDa is present in Alzheimer brain. Journal of neurochemistry. vol 58. issue 6. 1992-06-04. PMID:1374115. |
two abnormal entities of 69 and 130 kda, immunologically related to the microtubule-associated tau proteins, are present in the hippocampus and the frontal cortex of the alzheimer brain, which contain a large number of neurofibrillary tangles (nfts), but are absent in the cerebellum, which does not contain these structures. |
1992-06-04 |
2023-08-11 |
Not clear |
| K A Jobst, A D Smith, C S Barker, A Wear, E M King, A Smith, P A Anslow, A J Molyneux, B J Shepstone, N Sope. Association of atrophy of the medial temporal lobe with reduced blood flow in the posterior parietotemporal cortex in patients with a clinical and pathological diagnosis of Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry. vol 55. issue 3. 1992-05-20. PMID:1564478. |
all 10 patients with histopathologically diagnosed alzheimer's disease had shown a combination of hippocampal atrophy and reduced parietotemporal blood flow in life. |
1992-05-20 |
2023-08-11 |
Not clear |
| B M Ross, J T Knowler, J McCulloc. On the stability of messenger RNA and ribosomal RNA in the brains of control human subjects and patients with Alzheimer's disease. Journal of neurochemistry. vol 58. issue 5. 1992-05-11. PMID:1560235. |
the levels of the mrnas encoding the g protein subunits gs alpha, g beta 1, and g beta 2 were measured by northern blotting in the frontal cortex and hippocampus of control subjects and of patients with a clinical and histopathological diagnosis of dementia of the alzheimer type (dat). |
1992-05-11 |
2023-08-11 |
human |
| H Fukuyama, K Harada, H Yamauchi, T Miyoshi, S Yamaguchi, J Kimura, M Kameyama, M Senda, Y Yonekura, J Konish. Coronal reconstruction images of glucose metabolism in Alzheimer's disease. Journal of the neurological sciences. vol 106. issue 2. 1992-04-28. PMID:1802960. |
the medial part of the temporal lobes in alzheimer's disease did show a mildly lower glucose metabolic rate than that in normal controls; therefore it is suggested that the parietal and lateral parts of the temporal lobes are primary affected regions in alzheimer's disease, not the medial part of the temporal lobe, including the hippocampus. |
1992-04-28 |
2023-08-11 |
Not clear |