| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Söderberg, C Edlund, K Kristensson, G Dallne. Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids. vol 26. issue 6. 1991-09-27. PMID:1881238. |
aging has no influence on the fa compositions, while in alzheimer's disease (ad) pe is modified in all four regions, particularly in frontal gray matter and in hippocampus. |
1991-09-27 |
2023-08-11 |
human |
| H J Gertz, H Krüger, S Patt, J Cervos-Navarr. Tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area CA1 of the hippocampus in Alzheimer's disease. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1714332. |
tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area ca1 of the hippocampus in alzheimer's disease. |
1991-09-19 |
2023-08-11 |
Not clear |
| H J Gertz, H Krüger, S Patt, J Cervos-Navarr. Tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area CA1 of the hippocampus in Alzheimer's disease. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1714332. |
to elucidate the pathogenetic significance of neurofibrillary tangles in alzheimer's disease, the dendritic tree of tangle-bearing and unaffected pyramidal cells of area ca1 of the hippocampus was morphometrically examined. |
1991-09-19 |
2023-08-11 |
Not clear |
| J O Rinne, T Myllykylä, P Lönnberg, P Marjamäk. A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease. Brain research. vol 547. issue 1. 1991-09-05. PMID:1860068. |
brain nicotinic receptors were studied in the frontal cortex, temporal cortex, hippocampus and caudate nucleus in patients with parkinson's disease (pd), alzheimer's disease (ad) and control. |
1991-09-05 |
2023-08-11 |
Not clear |
| I Ceballos, F Javoy-Agid, A Delacourte, A Defossez, M Lafon, E Hirsch, A Nicole, P M Sinet, Y Agi. Neuronal localization of copper-zinc superoxide dismutase protein and mRNA within the human hippocampus from control and Alzheimer's disease brains. Free radical research communications. vol 12-13 Pt 2. 1991-08-07. PMID:2060834. |
neuronal localization of copper-zinc superoxide dismutase protein and mrna within the human hippocampus from control and alzheimer's disease brains. |
1991-08-07 |
2023-08-11 |
human |
| I Ceballos, F Javoy-Agid, A Delacourte, A Defossez, M Lafon, E Hirsch, A Nicole, P M Sinet, Y Agi. Neuronal localization of copper-zinc superoxide dismutase protein and mRNA within the human hippocampus from control and Alzheimer's disease brains. Free radical research communications. vol 12-13 Pt 2. 1991-08-07. PMID:2060834. |
in the hippocampus of an alzheimer's patient, successive immunostaining of the same tissue section by anticuzn sod and antipaired helical filaments antisera show that both normal and degenerating cells were labeled by the anticuzn sod antiserum. |
1991-08-07 |
2023-08-11 |
human |
| A Fine, B Ault, S I Rapopor. Mouse trisomy 16 neurons, a model of human trisomy 21 (Down syndrome), can be maintained by intracerebral transplantation. Neuroscience letters. vol 122. issue 1. 1991-08-01. PMID:1711657. |
we report that neural transplantation to normal hosts allows the maintenance of cortical and hippocampal neurons for at least 8 months, thus providing a model in which to examine pathological processes related to down syndrome, and perhaps to alzheimer's disease. |
1991-08-01 |
2023-08-11 |
mouse |
| P J Harrison, A J Barton, B McDonald, R C Pearso. Alzheimer's disease: specific increases in a G protein subunit (Gs alpha) mRNA in hippocampal and cortical neurons. Brain research. Molecular brain research. vol 10. issue 1. 1991-07-29. PMID:1647485. |
alzheimer's disease: specific increases in a g protein subunit (gs alpha) mrna in hippocampal and cortical neurons. |
1991-07-29 |
2023-08-11 |
human |
| P J Harrison, A J Barton, B McDonald, R C Pearso. Alzheimer's disease: specific increases in a G protein subunit (Gs alpha) mRNA in hippocampal and cortical neurons. Brain research. Molecular brain research. vol 10. issue 1. 1991-07-29. PMID:1647485. |
in situ hybridization histochemistry (ishh) with a 35s-labelled oligonucleotide has been used to detect the mrna encoding the alpha subunit of gs (gs alpha) in human hippocampus, temporal and visual cortices and cerebellum, and its level has been compared between alzheimer's disease (ad) and control brains. |
1991-07-29 |
2023-08-11 |
human |
| K L Jansen, R L Faull, M Dragunow, B L Syne. Alzheimer's disease: changes in hippocampal N-methyl-D-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors--an autoradiographic study. Neuroscience. vol 39. issue 3. 1991-07-23. PMID:1965859. |
alzheimer's disease: changes in hippocampal n-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors--an autoradiographic study. |
1991-07-23 |
2023-08-11 |
Not clear |
| D R Brady, E J Mufso. Alz-50 immunoreactive neuropil differentiates hippocampal complex subfields in Alzheimer's disease. The Journal of comparative neurology. vol 305. issue 3. 1991-07-03. PMID:2037717. |
alz-50 immunoreactive neuropil differentiates hippocampal complex subfields in alzheimer's disease. |
1991-07-03 |
2023-08-11 |
Not clear |
| N Hershkowitz, M A Rogawsk. Tetrahydroaminoacridine block of N-methyl-D-aspartate-activated cation channels in cultured hippocampal neurons. Molecular pharmacology. vol 39. issue 5. 1991-06-21. PMID:1709720. |
the action of tetrahydroaminoacridine (tha), a centrally active cholinesterase inhibitor that may provide symptomatic benefit in alzheimer's disease, was studied on responses to the excitatory amino acid n-methyl-d-aspartate (nmda) in cultured hippocampal neurons, using whole-cell voltage-clamp and single-channel recording techniques. |
1991-06-21 |
2023-08-11 |
Not clear |
| R Quirion, I Aubert, Y Robitaille, S Gauthier, D M Araujo, J G Chabo. Neurochemical deficits in pathological brain aging: specificity and possible relevance for treatment strategies. Clinical neuropharmacology. vol 13 Suppl 3. 1991-06-21. PMID:2093419. |
for example, the densities of forebrain cholinergic neurons are markedly decreased in cortical and hippocampal (but not striatal) areas in alzheimer's disease. |
1991-06-21 |
2023-08-11 |
Not clear |
| D Jaarsma, J B Sebens, J Kor. Reduction of adenosine A1-receptors in the perforant pathway terminal zone in Alzheimer hippocampus. Neuroscience letters. vol 121. issue 1-2. 1991-05-29. PMID:1850501. |
reduction of adenosine a1-receptors in the perforant pathway terminal zone in alzheimer hippocampus. |
1991-05-29 |
2023-08-11 |
rat |
| D Jaarsma, J B Sebens, J Kor. Reduction of adenosine A1-receptors in the perforant pathway terminal zone in Alzheimer hippocampus. Neuroscience letters. vol 121. issue 1-2. 1991-05-29. PMID:1850501. |
in the present study the density of a1-receptors in the hippocampus of alzheimer's disease (ad) patients (n = 9) and non-dement controls (n = 3) has been investigated autoradiographically with [3h]8-cyclopentyl-1,3-dipropylxanthine ([3h]cpdpx) as the ligand probe. |
1991-05-29 |
2023-08-11 |
rat |
| M Asanuma, N Ogawa, Y H Sora, K Pongdhana, K Haba, A Mor. Alterations of somatostatin and its modulation by levodopa in MPTP-treated mouse brain. Journal of the neurological sciences. vol 100. issue 1-2. 1991-05-28. PMID:1708406. |
since it has been reported that srif concentrations are significantly reduced in the frontal cortex and hippocampus of demented parkinsonians and patients with senile dementia of the alzheimer type and that levodopa treatment induced various psychiatric side effects, the results of the present study suggest some relationship among levodopa treatment, srif depletion and the demented state. |
1991-05-28 |
2023-08-11 |
mouse |
| C Bancher, I Grundke-Iqbal, K Iqbal, V A Fried, H T Smith, H M Wisniewsk. Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease. Brain research. vol 539. issue 1. 1991-05-22. PMID:1849776. |
on tissue sections of alzheimer brain, 4 antibodies to tau immunolabel not only neurofibrillary tangles, neuritic plaques and neuropil threads but also the tangle-free cytoplasm of a subset of hippocampal and cortical neurons we believe to be at a stage of alteration preceding the formation of paired helical filaments (phf). |
1991-05-22 |
2023-08-11 |
Not clear |
| M J Somerville, M E Percy, C Bergeron, L K Yoong, E A Grima, D R McLachla. Localization and quantitation of 68 kDa neurofilament and superoxide dismutase-1 mRNA in Alzheimer brains. Brain research. Molecular brain research. vol 9. issue 1-2. 1991-05-21. PMID:1850065. |
the cerebellar cortex and hippocampal ca1 and ca2 regions were compared in these two groups of subjects, since in ad the ca2 region of the hippocampus and the cerebellum have been found to be relatively unaffected by the alzheimer process in comparison to the hippocampal ca1 region. |
1991-05-21 |
2023-08-11 |
human |
| K M Parks, J E Sugar, V Haroutunian, L Bierer, D Perl, W C Wallac. Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem tissues. Brain research. Molecular brain research. vol 9. issue 1-2. 1991-05-21. PMID:1850067. |
homogenates prepared from the temporal cortex and hippocampus of individuals who had histopathologically confirmed alzheimer's disease exhibited reduced in vitro cyclic amp-dependent phosphorylation of synapsin i, neuronal phosphoprotein. |
1991-05-21 |
2023-08-11 |
Not clear |
| J F Flood, J E Morley, E Robert. Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 8. 1991-05-15. PMID:2014256. |
the hippocampus, a brain structure importantly involved in learning and memory, consistently shows severe pathological changes and deposition of amyloid in patients with alzheimer disease. |
1991-05-15 |
2023-08-11 |
mouse |