| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nanthia A Suthana, Allison Krupa, Markus Donix, Alison Burggren, Arne D Ekstrom, Michael Jones, Linda M Ercoli, Karen J Miller, Prabha Siddarth, Gary W Small, Susan Y Bookheime. Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease. NeuroImage. vol 53. issue 3. 2011-01-03. PMID:20005961. |
reduced hippocampal ca2, ca3, and dentate gyrus activity in asymptomatic people at genetic risk for alzheimer's disease. |
2011-01-03 |
2023-08-12 |
human |
| Nanthia A Suthana, Allison Krupa, Markus Donix, Alison Burggren, Arne D Ekstrom, Michael Jones, Linda M Ercoli, Karen J Miller, Prabha Siddarth, Gary W Small, Susan Y Bookheime. Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease. NeuroImage. vol 53. issue 3. 2011-01-03. PMID:20005961. |
these results suggest that reduced neural activity in hippocampal subregions may underlie the compensatory increase in extrahippocampal activity in people with a genetic risk for alzheimer's disease prior to the onset of cognitive deficits. |
2011-01-03 |
2023-08-12 |
human |
| Susanne G Mueller, Norbert Schuff, Kristine Yaffe, Catherine Madison, Bruce Miller, Michael W Weine. Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease. Human brain mapping. vol 31. issue 9. 2011-01-03. PMID:20839293. |
hippocampal atrophy patterns in mild cognitive impairment and alzheimer's disease. |
2011-01-03 |
2023-08-12 |
Not clear |
| Susanne G Mueller, Norbert Schuff, Kristine Yaffe, Catherine Madison, Bruce Miller, Michael W Weine. Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease. Human brain mapping. vol 31. issue 9. 2011-01-03. PMID:20839293. |
histopathological studies and animal models suggest that hippocampal subfields may be differently affected by aging, alzheimer's disease (ad), and other diseases. |
2011-01-03 |
2023-08-12 |
Not clear |
| F H Bouwman, N A Verwey, M Klein, A Kok, M A Blankenstein, J D Sluimer, F Barkhof, W M van der Flier, P Schelten. New research criteria for the diagnosis of Alzheimer's disease applied in a memory clinic population. Dementia and geriatric cognitive disorders. vol 30. issue 1. 2010-12-22. PMID:20606438. |
in the newly proposed research criteria for alzheimer's disease (ad), patients are defined as having memory dysfunction in addition to either hippocampal atrophy or an abnormal cerebrospinal fluid (csf) profile. |
2010-12-22 |
2023-08-12 |
Not clear |
| Renaud La Joie, Marine Fouquet, Florence Mézenge, Brigitte Landeau, Nicolas Villain, Katell Mevel, Alice Pélerin, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Differential effect of age on hippocampal subfields assessed using a new high-resolution 3T MR sequence. NeuroImage. vol 53. issue 2. 2010-12-16. PMID:20600996. |
this contrasts with the predominant vulnerability of the ca1 subfield to alzheimer's disease reported in several previous studies, suggesting that the assessment of hippocampal subfields may improve the discrimination between normal and pathological aging. |
2010-12-16 |
2023-08-12 |
human |
| Stacey Fuller, Megan Steele, Gerald Münc. Activated astroglia during chronic inflammation in Alzheimer's disease--do they neglect their neurosupportive roles? Mutation research. vol 690. issue 1-2. 2010-12-02. PMID:19748514. |
alzheimer's disease (ad) is a neurodegenerative disorder, characterized histopathologically by the extracellular deposition of beta-amyloid peptide in senile plaques, as well as intracellular neurofibrillary tangles (nft) of hyperphosphorylated tau protein, extensive neuronal loss and synaptic changes in the hippocampus and cerebral cortex. |
2010-12-02 |
2023-08-12 |
Not clear |
| Balu Chakravarthy, Chantal Gaudet, Michel Ménard, Trevor Atkinson, Anna Chiarini, Ilaria Dal Prà, James Whitfiel. The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells. Biochemical and biophysical research communications. vol 401. issue 3. 2010-12-02. PMID:20875398. |
while we don't know what the impact of the cilial localization of p75(ntr) on dentate gyral adult neurogenesis and memory encoding might be, the cilia's amyloid β-activatable p75(ntr) receptors could be damaging or lethal to the hippocampal functioning of amyloid β-accumulating alzheimer brain. |
2010-12-02 |
2023-08-12 |
mouse |
| Faviola Alcantara-Gonzalez, Ismael Juarez, Oscar Solis, Isaura Martinez-Tellez, Israel Camacho-Abrego, Eliezer Masliah, Raul Mena, Gonzalo Flore. Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus, and nucleus accumbens in old rats after chronic donepezil administration. Synapse (New York, N.Y.). vol 64. issue 10. 2010-11-30. PMID:20336627. |
in alzheimer's disease brains, morphological changes in the dendrites of pyramidal neurons of the prefrontal cortex (pfc) and hippocampus have been observed. |
2010-11-30 |
2023-08-12 |
rat |
| Nicolas Villain, Marine Fouquet, Jean-Claude Baron, Florence Mézenge, Brigitte Landeau, Vincent de La Sayette, Fausto Viader, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease. Brain : a journal of neurology. vol 133. issue 11. 2010-11-30. PMID:20688814. |
hippocampal atrophy, posterior cingulate and frontal glucose hypometabolism, and white-matter tract disruption are well described early macroscopic events in alzheimer's disease. |
2010-11-30 |
2023-08-12 |
Not clear |
| Liana G Apostolova, Lisa Mosconi, Paul M Thompson, Amity E Green, Kristy S Hwang, Anthony Ramirez, Rachel Mistur, Wai H Tsui, Mony J de Leo. Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal. Neurobiology of aging. vol 31. issue 7. 2010-11-24. PMID:18814937. |
subregional hippocampal atrophy predicts alzheimer's dementia in the cognitively normal. |
2010-11-24 |
2023-08-12 |
human |
| Liana G Apostolova, Lisa Mosconi, Paul M Thompson, Amity E Green, Kristy S Hwang, Anthony Ramirez, Rachel Mistur, Wai H Tsui, Mony J de Leo. Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal. Neurobiology of aging. vol 31. issue 7. 2010-11-24. PMID:18814937. |
atrophic changes of the hippocampus are typically regarded as an early sign of alzheimer's dementia (ad). |
2010-11-24 |
2023-08-12 |
human |
| L Liu, Y Su, W Yang, M Xiao, J Gao, G H. Disruption of neuronal-glial-vascular units in the hippocampus of ovariectomized mice injected with D-galactose. Neuroscience. vol 169. issue 2. 2010-11-23. PMID:20493929. |
herein we addressed these issues in the hippocampus of an alzheimer's disease mouse model which was established by ovariectomy and then followed with 8 weeks of d-galactose injection. |
2010-11-23 |
2023-08-12 |
mouse |
| Markus Donix, Alison C Burggren, Nanthia A Suthana, Prabha Siddarth, Arne D Ekstrom, Allison K Krupa, Michael Jones, Laurel Martin-Harris, Linda M Ercoli, Karen J Miller, Gary W Small, Susan Y Bookheime. Family history of Alzheimer's disease and hippocampal structure in healthy people. The American journal of psychiatry. vol 167. issue 11. 2010-11-22. PMID:20686185. |
family history of alzheimer's disease and hippocampal structure in healthy people. |
2010-11-22 |
2023-08-12 |
human |
| L Prut, G Prenosil, S Willadt, K Vogt, J-M Fritschy, F Crestan. A reduction in hippocampal GABAA receptor alpha5 subunits disrupts the memory for location of objects in mice. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20180861. |
substances that selectively reduce alpha5-gaba(a) receptor function are currently developed as potential cognition enhancers for alzheimer's syndrome and other dementia, consistent with genetic studies implicating these receptors that are highly expressed in hippocampus in learning performance. |
2010-11-15 |
2023-08-12 |
mouse |
| Kelvin K Leung, Kai-Kai Shen, Josephine Barnes, Gerard R Ridgway, Matthew J Clarkson, Jurgen Fripp, Olivier Salvado, Fabrice Meriaudeau, Nick C Fox, Pierrick Bourgeat, Sébastien Ourseli. Increasing power to predict mild cognitive impairment conversion to Alzheimer's disease using hippocampal atrophy rate and statistical shape models. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 13. issue Pt 2. 2010-11-15. PMID:20879307. |
increasing power to predict mild cognitive impairment conversion to alzheimer's disease using hippocampal atrophy rate and statistical shape models. |
2010-11-15 |
2023-08-12 |
human |
| Alexandra Kuzyk, Marzena Kastyak, Veena Agrawal, Meghan Gallant, Gajjeraman Sivakumar, Margaret Rak, Marc R Del Bigio, David Westaway, Robert Julian, Kathleen M Goug. Association among amyloid plaque, lipid, and creatine in hippocampus of TgCRND8 mouse model for Alzheimer disease. The Journal of biological chemistry. vol 285. issue 41. 2010-11-04. PMID:20682779. |
association among amyloid plaque, lipid, and creatine in hippocampus of tgcrnd8 mouse model for alzheimer disease. |
2010-11-04 |
2023-08-12 |
mouse |
| Hideo Mukai, Tetsuya Kimoto, Yasushi Hojo, Suguru Kawato, Gen Murakami, Shimpei Higo, Yusuke Hatanaka, Mari Ogiue-Iked. Modulation of synaptic plasticity by brain estrogen in the hippocampus. Biochimica et biophysica acta. vol 1800. issue 10. 2010-11-03. PMID:19909788. |
the hippocampus is a center for learning and memory as well as a target of alzheimer's disease in aged humans. |
2010-11-03 |
2023-08-12 |
Not clear |
| Tsu Tshen Chuan. Neurogenesis in mouse models of Alzheimer's disease. Biochimica et biophysica acta. vol 1802. issue 10. 2010-11-02. PMID:20056145. |
such crucial properties of neurogenesis may at least partially underlie the improved learning and memory functions observed in the mouse when hippocampal neurogenesis is augmented, leading to the suggestion that neurogenesis induction may be a novel therapeutic approach for diseases with cognitive impairments such as alzheimer's disease (ad). |
2010-11-02 |
2023-08-12 |
mouse |
| Woojin Scott Kim, Surabhi Bhatia, David A Elliott, Lotta Agholme, Katarina Kågedal, Heather McCann, Glenda M Halliday, Kevin J Barnham, Brett Garne. Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons. Journal of Alzheimer's disease : JAD. vol 21. issue 1. 2010-11-02. PMID:20413849. |
increased atp-binding cassette transporter a1 expression in alzheimer's disease hippocampal neurons. |
2010-11-02 |
2023-08-12 |
mouse |