| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tania Valdes-Gonzalez, Naoko Goto-Inoue, Wakako Hirano, Hironobu Ishiyama, Takahiro Hayasaka, Mitsutoshi Setou, Takao Tak. New approach for glyco- and lipidomics--molecular scanning of human brain gangliosides by TLC-Blot and MALDI-QIT-TOF MS. Journal of neurochemistry. vol 116. issue 5. 2011-03-30. PMID:21244424. |
the results clearly showed a change of ganglioside composition, in addition to identifying individual ganglioside molecular species, in the hippocampus gray matter of patients with alzheimer's disease. |
2011-03-30 |
2023-08-12 |
human |
| Liana G Apostolova, Kristy S Hwang, John P Andrawis, Amity E Green, Sona Babakchanian, Jonathan H Morra, Jeffrey L Cummings, Arthur W Toga, John Q Trojanowski, Leslie M Shaw, Clifford R Jack, Ronald C Petersen, Paul S Aisen, William J Jagust, Robert A Koeppe, Chester A Mathis, Michael W Weiner, Paul M Thompso. 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiology of aging. vol 31. issue 8. 2011-03-29. PMID:20538372. |
cerebrospinal fluid (csf) measures of ab and tau, pittsburgh compound b (pib) imaging and hippocampal atrophy are promising alzheimer's disease biomarkers yet the associations between them are not known. |
2011-03-29 |
2023-08-12 |
human |
| A Caroli, G B Frison. The dynamics of Alzheimer's disease biomarkers in the Alzheimer's Disease Neuroimaging Initiative cohort. Neurobiology of aging. vol 31. issue 8. 2011-03-29. PMID:20538373. |
the aim of this study was to investigate the dynamics of four of the most validated biomarkers for alzheimer's disease (ad), cerebro-spinal fluid (csf) abeta 1-42, tau, hippocampal volume, and fdg-pet, in patients at different stage of ad. |
2011-03-29 |
2023-08-12 |
human |
| Sarah J Greene, Ronald J Killian. Subregions of the inferior parietal lobule are affected in the progression to Alzheimer's disease. Neurobiology of aging. vol 31. issue 8. 2011-03-29. PMID:20570398. |
changes in several regions within the brain have been associated with progression from healthy aging to alzheimer's disease (ad), including the hippocampus, entorhinal cortex, and the inferior parietal lobule (ipl). |
2011-03-29 |
2023-08-12 |
human |
| Thomas Deffieux, Elisa E Konofago. Numerical study of a simple transcranial focused ultrasound system applied to blood-brain barrier opening. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. vol 57. issue 12. 2011-03-29. PMID:21156360. |
the study addresses the transcranial targeting involved in ultrasound- induced blood-brain barrier (bbb) opening with clinically relevant targets such as the hippocampus and the basal ganglia, which are typically affected by early alzheimer's and parkinson's disease, respectively. |
2011-03-29 |
2023-08-12 |
human |
| Yan-Jiang Wang, Xin Wang, Jian-Jun Lu, Qiao-Xin Li, Chang-Yue Gao, Xiao-Hong Liu, Yin Sun, Miao Yang, Yoon Lim, Genevieve Evin, Jin-Hua Zhong, Colin Masters, Xin-Fu Zho. p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 6. 2011-03-25. PMID:21307265. |
accumulation of toxic amyloid-β (aβ) in the cerebral cortex and hippocampus is a major pathological feature of alzheimer's disease (ad). |
2011-03-25 |
2023-08-12 |
mouse |
| Ji Hyun Choi, A Young Choi, Hana Yoon, Wonchae Choe, Kyung-Sik Yoon, Joohun Ha, Eui-Ju Yeo, Insug Kan. Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction. Experimental & molecular medicine. vol 42. issue 12. 2011-03-23. PMID:20959717. |
because endoplasmic reticulum (er) stress has been implicated in neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, and cerebral ischemia, we investigated the effects of baicalein on apoptotic death of ht22 mouse hippocampal neuronal cells induced by thapsigargin (tg) and brefeldin a (bfa), two representative er stress inducers. |
2011-03-23 |
2023-08-12 |
mouse |
| Lidia Glodzik, Henry Rusinek, Miroslaw Brys, Wai H Tsui, Remigiusz Switalski, Lisa Mosconi, Rachel Mistur, Elizabeth Pirraglia, Susan de Santi, Yi Li, Alexander Goldowsky, Mony J de Leo. Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 2. 2011-03-17. PMID:20842159. |
hippocampus is vulnerable to both alzheimer's disease (ad) pathology and ischemia; nonetheless, the information about the impact of vascular risk on hippocampal perfusion is minimal. |
2011-03-17 |
2023-08-12 |
human |
| F F Cruz-Sánchez, X Gironès, A Ortega, F Alameda, J V Lafuent. Oxidative stress in Alzheimer's disease hippocampus: a topographical study. Journal of the neurological sciences. vol 299. issue 1-2. 2011-03-16. PMID:20863531. |
oxidative stress in alzheimer's disease hippocampus: a topographical study. |
2011-03-16 |
2023-08-12 |
Not clear |
| F F Cruz-Sánchez, X Gironès, A Ortega, F Alameda, J V Lafuent. Oxidative stress in Alzheimer's disease hippocampus: a topographical study. Journal of the neurological sciences. vol 299. issue 1-2. 2011-03-16. PMID:20863531. |
results suggest that an oxidative stress pathway starts in the ca3 sector progresses to ca1 and then continues to other hippocampal and cortical areas building a pathoclitic pathway for alzheimer's disease progression. |
2011-03-16 |
2023-08-12 |
Not clear |
| Mathieu Verdurand, Anne Bérod, Didier Le Bars, Luc Zimme. Effects of amyloid-β peptides on the serotoninergic 5-HT1A receptors in the rat hippocampus. Neurobiology of aging. vol 32. issue 1. 2011-03-14. PMID:19249128. |
a recent [(18)f]mppf-positron emission tomography study has highlighted an overexpression of 5-ht(1a) receptors in the hippocampus of patients with mild cognitive impairment compared to a decrease in those with alzheimer's disease (ad) [truchot, l., costes, s.n., zimmer, l., laurent, b., le bars, d., thomas-antérion, c., croisile, b., mercier, b., hermier, m., vighetto, a., krolak-salmon, p., 2007. |
2011-03-14 |
2023-08-12 |
rat |
| A M Espinosa-Oliva, R M de Pablos, R F Villarán, S Argüelles, J L Venero, A Machado, J Can. Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus. Neurobiology of aging. vol 32. issue 1. 2011-03-14. PMID:19286276. |
the hippocampus is insensitive to strong inflammatory stimulus under normal conditions and one of the most severely affected areas in alzheimer's disease. |
2011-03-14 |
2023-08-12 |
rat |
| Zhiqian Tong, Jinling Zhang, Wenhong Luo, Weishan Wang, Fangxu Li, Hui Li, Hongjun Luo, Jing Lu, Jiangning Zhou, You Wan, Rongqiao H. Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiology of aging. vol 32. issue 1. 2011-03-14. PMID:19879019. |
formaldehyde level was analyzed by high-performance liquid chromatography (with fluorescence detection) in human urine from dementia patients (n=141), patients with hypertension (n=33) or diabetes (n=16) and healthy individuals (n=38), autopsy hippocampus samples from alzheimer's disease (ad) patients and brains of three types of ad animal model: namely, senescence accelerated mice (samp8), app-transgenic mice and app/ps1-transgenic mice. |
2011-03-14 |
2023-08-12 |
mouse |
| Zhiqian Tong, Jinling Zhang, Wenhong Luo, Weishan Wang, Fangxu Li, Hui Li, Hongjun Luo, Jing Lu, Jiangning Zhou, You Wan, Rongqiao H. Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiology of aging. vol 32. issue 1. 2011-03-14. PMID:19879019. |
furthermore, formaldehyde levels were significantly increased in the autopsy hippocampus from alzheimer's patients (n=4). |
2011-03-14 |
2023-08-12 |
mouse |
| Y J Hong, B Yoon, Y S Shim, A H Cho, S C Lim, K J Ahn, D W Yan. Differences in microstructural alterations of the hippocampus in Alzheimer disease and idiopathic normal pressure hydrocephalus: a diffusion tensor imaging study. AJNR. American journal of neuroradiology. vol 31. issue 10. 2011-03-11. PMID:20671063. |
differences in microstructural alterations of the hippocampus in alzheimer disease and idiopathic normal pressure hydrocephalus: a diffusion tensor imaging study. |
2011-03-11 |
2023-08-12 |
Not clear |
| Y Y Li, J G Cui, J M Hill, S Bhattacharjee, Y Zhao, W J Luki. Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models. Neuroscience letters. vol 487. issue 1. 2011-03-09. PMID:20934487. |
in this study we examined mirna-146a levels in early-, moderate- and late-stage alzheimer's disease (ad) neocortex and hippocampus, in several human primary brain and retinal cell lines, and in 5 different transgenic mouse models of ad including tg2576, tgcrnd8, psapp, 3xtg-ad and 5xfad. |
2011-03-09 |
2023-08-12 |
mouse |
| Xiao-Ping Hong, Cai-Xia Peng, Wei Wei, Qing Tian, Ying-Hua Liu, Xiu-Qing Yao, Yao Zhang, Fu-Yuan Cao, Qun Wang, Jian-Zhi Wan. Essential role of tau phosphorylation in adult hippocampal neurogenesis. Hippocampus. vol 20. issue 12. 2011-03-07. PMID:19816983. |
an increased hippocampal neurogenesis has been observed in alzheimer disease (ad), the most common neurodegenerative disorder characterized with accumulation of β-amyloid (aβ) and hyperphosphorylated tau (p-tau). |
2011-03-07 |
2023-08-12 |
mouse |
| Patricia F Kao, David A Davis, Meredith G Banigan, Charles R Vanderburg, Sudha Seshadri, Ivana Delall. Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. PloS one. vol 5. issue 10. 2011-03-07. PMID:20967212. |
modulators of cytoskeletal reorganization in ca1 hippocampal neurons show increased expression in patients at mid-stage alzheimer's disease. |
2011-03-07 |
2023-08-12 |
Not clear |
| Patricia F Kao, David A Davis, Meredith G Banigan, Charles R Vanderburg, Sudha Seshadri, Ivana Delall. Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. PloS one. vol 5. issue 10. 2011-03-07. PMID:20967212. |
during the progression of alzheimer's disease (ad), hippocampal neurons undergo cytoskeletal reorganization, resulting in degenerative as well as regenerative changes. |
2011-03-07 |
2023-08-12 |
Not clear |
| G L Odero, K Oikawa, K A C Glazner, J Schapansky, D Grossman, J D Thiessen, A Motnenko, N Ge, M Martin, G W Glazner, B C Albens. Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20399254. |
to test the hypothesis that calcium-related mechanisms, such as changes in calcium buffering, are associated with alterations in ltp and memory, we utilized in vitro experimental paradigms of ltp in hippocampal slices obtained from the ps1-m146v transgenic mouse model of alzheimer's disease (ad). |
2011-03-04 |
2023-08-12 |
mouse |