| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fabio Di Domenico, Joshua B Owen, Rukhsana Sultana, Rena A Sowell, Marzia Perluigi, Chiara Cini, Jian Cai, William M Pierce, D Allan Butterfiel. The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression. Journal of neuroscience research. vol 88. issue 16. 2011-03-03. PMID:20936705. |
the wheat germ agglutinin-fractionated proteome of subjects with alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: implications for disease pathogenesis and progression. |
2011-03-03 |
2023-08-12 |
human |
| Fabio Di Domenico, Joshua B Owen, Rukhsana Sultana, Rena A Sowell, Marzia Perluigi, Chiara Cini, Jian Cai, William M Pierce, D Allan Butterfiel. The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression. Journal of neuroscience research. vol 88. issue 16. 2011-03-03. PMID:20936705. |
the current study utilizes wga affinity chromatography to fractionate proteins from hippocampus and inferior parietal lobule (ipl) from subjects with alzheimer's disease (ad) and arguably its earliest form, mild cognitive impairment (mci). |
2011-03-03 |
2023-08-12 |
human |
| N A Kapai, E I Solntseva, V G Skrebitski. Donepezil eliminates suppressive effects of β-amyloid peptide (1-42) on long-term potentiation in the hippocampus. Bulletin of experimental biology and medicine. vol 149. issue 1. 2011-03-02. PMID:21113452. |
application of donepezil, a drug used for the treatment of alzheimer disease, in a concentration of 1 μm eliminates the suppressive effect of β-amyloid peptide 1-42 on long-term posttenanic potentiation in the hippocampus. |
2011-03-02 |
2023-08-12 |
rat |
| Stephen D Ginsberg, Melissa J Alldred, Scott E Counts, Anne M Cataldo, Rachael L Neve, Ying Jiang, Joanne Wuu, Moses V Chao, Elliott J Mufson, Ralph A Nixon, Shaoli Ch. Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression. Biological psychiatry. vol 68. issue 10. 2011-03-01. PMID:20655510. |
endocytic dysfunction and neurotrophin signaling deficits may underlie the selective vulnerability of hippocampal neurons during the progression of alzheimer's disease (ad), although there is little direct in vivo and biochemical evidence to support this hypothesis. |
2011-03-01 |
2023-08-12 |
Not clear |
| Zhong-Li Zhang, Yue-Ming Zuo, Qiu-Hong Wang, Hong-Bin Xiao, Hai-Xue Kuan. [Effects of Valeriana amurensis on the expressions of iNOS, COX-2 and IkappaCB-alpha in Alzheimer's disease model rat's brain]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. vol 33. issue 4. 2011-03-01. PMID:20845789. |
on the inflammation reaction of cortical neurons and hippocampus neuronsin in alzheimer's disease model rat's brain. |
2011-03-01 |
2023-08-12 |
rat |
| Odete A B da Cruz e Silva, Ana Gabriela Henriques, Sara Catarina Timóteo Santos Domingues, Edgar F da Cruz e Silv. Wnt signalling is a relevant pathway contributing to amyloid beta- peptide-mediated neuropathology in Alzheimer's disease. CNS & neurological disorders drug targets. vol 9. issue 6. 2011-02-28. PMID:20942790. |
individuals with alzheimer's disease (ad) exhibit extracellular senile plaques (sps) of aggregated a beta and intracellular neurofibrillary tangles that contain hyperphosphorylated tau protein (nfts), and also an extensive loss in basal forebrain cholinergic neurons that innervate the hippocampus and neocortex. |
2011-02-28 |
2023-08-12 |
mouse |
| Joshua B Owen, Rukhsana Sultana, Christopher D Aluise, Michelle A Erickson, Tulin O Price, Guojun Bu, William A Banks, D Allan Butterfiel. Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aβ accumulation in AD brain. Free radical biology & medicine. vol 49. issue 11. 2011-02-23. PMID:20869432. |
oxidative modification to ldl receptor-related protein 1 in hippocampus from subjects with alzheimer disease: implications for aβ accumulation in ad brain. |
2011-02-23 |
2023-08-12 |
human |
| Mikel L Olson, Ian J Cer. Intrahippocampal Norleucine¹-Angiotensin IV mitigates scopolamine-induced spatial working memory deficits. Peptides. vol 31. issue 12. 2011-02-10. PMID:20816712. |
depletion of cholinergic neurons in the hippocampus has been implicated in memory impairment and alzheimer's disease (ad). |
2011-02-10 |
2023-08-12 |
rat |
| Mert R Sabuncu, B T Thomas Yeo, Koen Van Leemput, Bruce Fischl, Polina Gollan. A generative model for image segmentation based on label fusion. IEEE transactions on medical imaging. vol 29. issue 10. 2011-02-07. PMID:20562040. |
in a second experiment, we use brain mri scans of 282 subjects to demonstrate that the proposed segmentation tool is sufficiently sensitive to robustly detect hippocampal volume changes in a study of aging and alzheimer's disease. |
2011-02-07 |
2023-08-12 |
human |
| Yue-ming Zuo, Zhong-li Zhang, Qiu-hong Wang, Ning Xie, Hai-xue Kuan. [Effects of Valeriana amurensis on the expressions of beta-APP, Abeta(1-40) and caspase-3 in Alzheimer's disease model rat's brain]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. vol 33. issue 2. 2011-02-03. PMID:20575418. |
to investigate the effects of valeriana amurensis on the expressions of p-app,a4,1 and caspase-3 of cortical neurons and hippocampus neurons in in alzheimer's disease model rats' brain. |
2011-02-03 |
2023-08-12 |
rat |
| Marcello D'Amelio, Virve Cavallucci, Silvia Middei, Cristina Marchetti, Simone Pacioni, Alberto Ferri, Adamo Diamantini, Daniela De Zio, Paolo Carrara, Luca Battistini, Sandra Moreno, Alberto Bacci, Martine Ammassari-Teule, Hélène Marie, Francesco Ceccon. Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nature neuroscience. vol 14. issue 1. 2011-02-03. PMID:21151119. |
we found a non-apoptotic baseline caspase-3 activity in hippocampal dendritic spines and an enhancement of this activity at the onset of memory decline in the tg2576-appswe mouse model of alzheimer's disease. |
2011-02-03 |
2023-08-12 |
mouse |
| Yakeel T Quiroz, Andrew E Budson, Kim Celone, Adriana Ruiz, Randall Newmark, Gabriel Castrillón, Francisco Lopera, Chantal E Ster. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease. Annals of neurology. vol 68. issue 6. 2011-01-31. PMID:21194156. |
hippocampal hyperactivation in presymptomatic familial alzheimer's disease. |
2011-01-31 |
2023-08-12 |
human |
| Yan Zeng, Danyun Zhao, Cui-Wei Xi. Neurotrophins enhance CaMKII activity and rescue amyloid-β-induced deficits in hippocampal synaptic plasticity. Journal of Alzheimer's disease : JAD. vol 21. issue 3. 2011-01-18. PMID:20634586. |
amyloid-β (aβ) peptide-induced impairment of hippocampal synaptic plasticity is considered an underlying mechanism for memory loss in the early stages of alzheimer's disease and its animal models. |
2011-01-18 |
2023-08-12 |
rat |
| Stephen M Fitzjohn, Frederick Kuenzi, Robin A Morton, Thomas W Rosahl, Huw Lewis, David Smith, Guy R Seabrook, Graham L Collingridg. A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1. Molecular brain. vol 3. issue 1. 2011-01-14. PMID:20630068. |
synaptic transmission and long-term potentiation (ltp) in the ca1 region of hippocampal slices have been studied during ageing of a double transgenic mouse strain relevant to early-onset familial alzheimer's disease (ad). |
2011-01-14 |
2023-08-12 |
mouse |
| H N Noristani, M Olabarria, A Verkhratsky, J J Rodrígue. Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20576032. |
serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the ca1 area of hippocampus in a triple transgenic mouse model of alzheimer's disease. |
2011-01-13 |
2023-08-12 |
mouse |
| H N Noristani, M Olabarria, A Verkhratsky, J J Rodrígue. Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20576032. |
alzheimer's disease (ad) is a neurodegenerative disease that deteriorates cognitive functions and associated brain regions such as the hippocampus, being the primary cause of dementia. |
2011-01-13 |
2023-08-12 |
mouse |
| Tong Zhang, Zhiping Mi, Nina F Scho. Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor. Oxidative medicine and cellular longevity. vol 2. issue 4. 2011-01-12. PMID:20716910. |
furthermore, oxidative and inflammatory injury to the cholinergic neurons of the nucleus basalis of meynert and hippocampus plays a critical role in the pathology of alzheimer's disease. |
2011-01-12 |
2023-08-12 |
rat |
| Simon Gengler, Alison Hamilton, Christian Hölsche. Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice. PloS one. vol 5. issue 3. 2011-01-11. PMID:20339537. |
synaptic plasticity in the hippocampus of a app/ps1 mouse model of alzheimer's disease is impaired in old but not young mice. |
2011-01-11 |
2023-08-12 |
mouse |
| Jian Guo Cui, Yuan Yuan Li, Yuhai Zhao, Surjyadipta Bhattacharjee, Walter J Luki. Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease. The Journal of biological chemistry. vol 285. issue 50. 2011-01-10. PMID:20937840. |
here we extend those observations to the hippocampus and neocortex of alzheimer disease (ad) brain and to stressed human astroglial (hag) cells in primary culture. |
2011-01-10 |
2023-08-12 |
human |
| Olga Meulenbroek, Mark Rijpkema, Roy P C Kessels, Marcel G M Olde Rikkert, Guillén Fernánde. Autobiographical memory retrieval in patients with Alzheimer's disease. NeuroImage. vol 53. issue 1. 2011-01-04. PMID:20570740. |
onset of alzheimer's disease enhances this pattern, but the neural underpinnings of this change in autobiographical memory (am), in particular the role of hippocampal degradation, are unknown. |
2011-01-04 |
2023-08-12 |
Not clear |