| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J De Reuck, D Caparros-Lefebvre, V Deramecourt, C A Maurag. Hippocampal microbleed on a post-mortem t(2)∗-weighted gradient-echo 7.0-tesla magnetic resonance imaging? Case reports in neurology. vol 3. issue 3. 2012-10-02. PMID:22121349. |
the present post-mortem study of a brain from an alzheimer patient showed on a t(2)∗-weighted gradient-echo 7.0-t mri of a coronal brain section a hyposignal in the hippocampus, suggesting a microbleed. |
2012-10-02 |
2023-08-12 |
Not clear |
| R Shinagawa, S Masuda, R Sasaki, K Ikura, K Takahat. In vitro neurotoxicity of amyloid β-peptide cross-linked by transglutaminase. Cytotechnology. vol 23. issue 1-3. 2012-10-02. PMID:22358523. |
transglutaminase-treated aβ retarded neurite extension of pc12 cells, and rat cultured neurons of hippocampus and septum, brain areas severely affected by alzheimer disease, and subsequently caused cell death, whereas the transglutaminase-untreated counterparts did not show harmful effects. |
2012-10-02 |
2023-08-12 |
rat |
| Dong Young Lee, Evan Fletcher, Owen Thomas Carmichael, Baljeet Singh, Dan Mungas, Bruce Reed, Oliver Martinez, Michael H Buonocore, Maria Persianinova, Charles Decarl. Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer's Disease. Frontiers in aging neuroscience. vol 4. 2012-10-02. PMID:22514534. |
sub-regional hippocampal injury is associated with fornix degeneration in alzheimer's disease. |
2012-10-02 |
2023-08-12 |
Not clear |
| Dong Young Lee, Evan Fletcher, Owen Thomas Carmichael, Baljeet Singh, Dan Mungas, Bruce Reed, Oliver Martinez, Michael H Buonocore, Maria Persianinova, Charles Decarl. Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer's Disease. Frontiers in aging neuroscience. vol 4. 2012-10-02. PMID:22514534. |
we examined in vivo evidence of axonal degeneration in association with neuronal pathology in alzheimer's disease (ad) through analysis of fornix microstructural integrity and measures of hippocampal subfield atrophy. |
2012-10-02 |
2023-08-12 |
Not clear |
| Heikki Tanil. Wading pools, fading memories-place navigation in transgenic mouse models of Alzheimer's disease. Frontiers in aging neuroscience. vol 4. 2012-10-02. PMID:22670146. |
this review focuses on task details that are most relevant for its application to mouse studies in general and characteristic patterns of impaired performance in alzheimer model mice as compared with rodents sustaining hippocampal lesions. |
2012-10-02 |
2023-08-12 |
mouse |
| Philippe Taupi. Adult neurogenesis and neural stem cells as a model for the discovery and development of novel drugs. Expert opinion on drug discovery. vol 5. issue 10. 2012-10-02. PMID:22823987. |
it is enhanced in the hippocampus of animal models and patients with neurological diseases and disorders, such as alzheimer's disease (ad) and epilepsy. |
2012-10-02 |
2023-08-12 |
Not clear |
| Takayuki Masaki, Futoshi Anan, Tsuyoshi Shimomura, Minoru Fujiki, Tetsunori Saikawa, Hironobu Yoshimats. Association between hippocampal volume and serum adiponectin in patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 61. issue 8. 2012-10-01. PMID:22405025. |
hippocampus volume was measured by computer-assisted analysis using a magnetic resonance imaging (mri) voxel-based specific regional analysis system developed for the study of alzheimer's disease as the end point for assessment of hippocampus volume. |
2012-10-01 |
2023-08-12 |
Not clear |
| Beverly M Francis, John Kim, Meredith E Barakat, Stephan Fraenkl, Yeni H Yücel, Shiyong Peng, Bernadeta Michalski, Margaret Fahnestock, Joanne McLaurin, Howard T J Moun. Object recognition memory and BDNF expression are reduced in young TgCRND8 mice. Neurobiology of aging. vol 33. issue 3. 2012-09-28. PMID:20447730. |
the tgcrnd8 mouse model of alzheimer's disease exhibits progressive cortical and hippocampal β-amyloid accumulation, resulting in plaque pathology and spatial memory impairment by 3 months of age. |
2012-09-28 |
2023-08-12 |
mouse |
| Jolanta Galazka-Friedman, Erika R Bauminger, Karol Szlachta, Andrzej Friedma. The role of iron in neurodegeneration--Mössbauer spectroscopy, electron microscopy, enzyme-linked immunosorbent assay and neuroimaging studies. Journal of physics. Condensed matter : an Institute of Physics journal. vol 24. issue 24. 2012-09-28. PMID:22595616. |
the measurements were made on human tissues extracted from liver and from brain structures involved in diseases of the human brain: substantia nigra (parkinson's, pd), hippocampal cortex (alzheimer's, ad) and globus pallidus (progressive supranuclear palsy, psp). |
2012-09-28 |
2023-08-12 |
human |
| Desiree Antequera, Aitziber Portero, Marta Bolos, Gorka Orive, Rosa M Rm A Hernández, José Luis Pedraz, Eva Carr. Encapsulated VEGF-secreting cells enhance proliferation of neuronal progenitors in the hippocampus of AβPP/Ps1 mice. Journal of Alzheimer's disease : JAD. vol 29. issue 1. 2012-09-21. PMID:22232015. |
vascular endothelial growth factor (vegf) promotes neurogenesis in the adult hippocampus, but the way in which this process occurs in the alzheimer's disease (ad) brain is still unknown. |
2012-09-21 |
2023-08-12 |
mouse |
| Ming Teng Ko. [Pharmacological treatment strategies targeting cognitive impairment associated with aging]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 139. issue 4. 2012-09-20. PMID:22498679. |
such therapy, in addition to memory improvement, may also have disease modifying potential because hippocampal overactivity in aging/mci predicts further cognitive decline and conversion to alzheimer's disease. |
2012-09-20 |
2023-08-12 |
rat |
| Olof Lindberg, Mark Walterfang, Jeffrey C L Looi, Nikolai Malykhin, Per Ostberg, Bram Zandbelt, Martin Styner, Beatriz Paniagua, Dennis Velakoulis, Eva Orndahl, Lars-Olof Wahlun. Hippocampal shape analysis in Alzheimer's disease and frontotemporal lobar degeneration subtypes. Journal of Alzheimer's disease : JAD. vol 30. issue 2. 2012-09-18. PMID:22414571. |
hippocampal shape analysis in alzheimer's disease and frontotemporal lobar degeneration subtypes. |
2012-09-18 |
2023-08-12 |
human |
| Olof Lindberg, Mark Walterfang, Jeffrey C L Looi, Nikolai Malykhin, Per Ostberg, Bram Zandbelt, Martin Styner, Beatriz Paniagua, Dennis Velakoulis, Eva Orndahl, Lars-Olof Wahlun. Hippocampal shape analysis in Alzheimer's disease and frontotemporal lobar degeneration subtypes. Journal of Alzheimer's disease : JAD. vol 30. issue 2. 2012-09-18. PMID:22414571. |
hippocampal pathology is central to alzheimer's disease (ad) and other forms of dementia such as frontotemporal lobar degeneration (ftld). |
2012-09-18 |
2023-08-12 |
human |
| Caterina M Hernandez, Kelly T Dinele. α7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both? Current drug targets. vol 13. issue 5. 2012-09-17. PMID:22300028. |
several studies suggest that α7 nicotinic receptor (nachr) activation represents a useful therapeutic strategy for the cognitive impairments associated with early alzheimer's disease as the α7 subtype of nicotinic acetylcholine receptors are expressed by basal forebrain cholinergic projection neurons as well as by their targets in the hippocampus. |
2012-09-17 |
2023-08-12 |
mouse |
| Desiree Antequera, Marta Bolos, Carlos Spuch, Consuelo Pascual, Isidro Ferrer, María Isabel Fernandez-Bachiller, María Isabel Rodríguez-Franco, Eva Carr. Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease. Neurobiology of disease. vol 46. issue 3. 2012-09-14. PMID:22426395. |
effects of a tacrine-8-hydroxyquinoline hybrid (iqm-622) on aβ accumulation and cell death: involvement in hippocampal neuronal loss in alzheimer's disease. |
2012-09-14 |
2023-08-12 |
mouse |
| Shuang-Qing Chen, Qing Cai, Yu-Ying Shen, Pei-Jun Wang, Gao-Jun Teng, Ming-Hua Li, Wei Zhang, Feng-Chao Zan. (1)H-MRS evaluation of therapeutic effect of neural stem cell transplantation on Alzheimer's disease in AβPP/PS1 double transgenic mice. Journal of Alzheimer's disease : JAD. vol 28. issue 1. 2012-09-12. PMID:21955813. |
the aim of this work was to explore the applicable value of (1)h-mrs evaluation on the treatment of alzheimer's disease (ad) with neural stem cell (nsc) transplantation by quantitative analysis of metabolite changes in the hippocampal area in aβpp/ps1 transgenic (tg) mice. |
2012-09-12 |
2023-08-12 |
mouse |
| Shahar Barbash, Hermona Sore. Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22191566. |
threshold-independent meta-analysis of alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microrna regulation. |
2012-09-07 |
2023-08-12 |
Not clear |
| Philipp A Thomann, Ulrich Seidl, Julia Brinkmann, Dusan Hirjak, Tanja Traeger, R Christian Wolf, Marco Essig, Johannes Schrode. Hippocampal morphology and autobiographic memory in mild cognitive impairment and Alzheimer's disease. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22372439. |
hippocampal morphology and autobiographic memory in mild cognitive impairment and alzheimer's disease. |
2012-09-07 |
2023-08-12 |
Not clear |
| Huilian Shen, Yuta Fuchino, Daisuke Miyamoto, Hiroshi Nomura, Norio Matsuk. Vagus nerve stimulation enhances perforant path-CA3 synaptic transmission via the activation of β-adrenergic receptors and the locus coeruleus. The international journal of neuropsychopharmacology. vol 15. issue 4. 2012-09-05. PMID:21733240. |
the hippocampus is widely recognized to be related to epilepsy, depression, and alzheimer's disease. |
2012-09-05 |
2023-08-12 |
rat |
| Michelle M Mielke, Ozioma C Okonkwo, Kenichi Oishi, Susumu Mori, Sarah Tighe, Michael I Miller, Can Ceritoglu, Timothy Brown, Marilyn Albert, Constantine G Lyketso. Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 8. issue 2. 2012-09-05. PMID:22404852. |
fornix integrity and hippocampal volume predict memory decline and progression to alzheimer's disease. |
2012-09-05 |
2023-08-12 |
Not clear |