| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Bu, Yanmin Zhang, Yeledan Mahan, Shen Shi, Xuanxia Wu, Xiaoling Zhang, Zhaoxia Wang, Ling Zho. Acacetin improves cognitive function of APP/PS1 Alzheimer's disease model mice via the NLRP3 inflammasome signaling pathway. Translational neuroscience. vol 13. issue 1. 2022-11-16. PMID:36382256. |
acacetin improves cognitive function of app/ps1 alzheimer's disease model mice via the nlrp3 inflammasome signaling pathway. |
2022-11-16 |
2023-08-14 |
mouse |
| Xiaolin Xu, Xianli Wu, Gengyu Yue, Qimin An, Jun Lou, Xiaoxu Yang, Zhe Jin, Jianhong Ding, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xi. The role of Nod-like receptor protein 3 inflammasome activated by ion channels in multiple diseases. Molecular and cellular biochemistry. 2022-11-15. PMID:36378463. |
activation of the nlrp3 inflammasome is closely related to the occurrence of many diseases, such as alzheimer's disease. |
2022-11-15 |
2023-08-14 |
Not clear |
| Yuan Li, Haifeng Zhang, Weihong Long, Menghan Gao, Weiying Guo, Lu Y. Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation Aging. vol 14. 2022-11-15. PMID:36378718. |
inhibition of nlrp3 and golph3 ameliorates diabetes-induced neuroinflammation golgi stress has been observed in various neurodegenerative diseases, such as alzheimer's disease and parkinson's disease. |
2022-11-15 |
2023-08-14 |
Not clear |
| Min Yuan, Dong Wang, Jiaen Yang, Hai La. The NLR family pyrin domain containing 3 inflammasome in the mechanism of electroacupuncture: Current status and future perspectives. Frontiers in aging neuroscience. vol 14. 2022-11-07. PMID:36337711. |
the nlr family pyrin domain containing 3 (nlrp3) inflammasome is a thoroughly studied inflammasome that is closely associated with alzheimer's disease, spinal cord injury, and other diseases and plays an important role in the diagnosis and treatment of human immune system diseases. |
2022-11-07 |
2023-08-14 |
human |
| Ranran Lu, Lijie Zhang, Xinling Yan. Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease. Frontiers in aging neuroscience. vol 14. 2022-10-20. PMID:36262883. |
interaction between autophagy and the nlrp3 inflammasome in alzheimer's and parkinson's disease. |
2022-10-20 |
2023-08-14 |
Not clear |
| Ranran Lu, Lijie Zhang, Xinling Yan. Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease. Frontiers in aging neuroscience. vol 14. 2022-10-20. PMID:36262883. |
this article aims to review recent research on the interaction of autophagy, nlrp3 inflammasome, and protein aggregates in alzheimer's disease (ad) and parkinson's disease (pd), analyze the mechanism and provide theoretical references for further research in the future. |
2022-10-20 |
2023-08-14 |
Not clear |
| Ya Gao, Shuyue Li, Yidan Zhang, Jian Zhang, Yuan Zhao, Cui Chang, Xuan Gao, Guofeng Yan. Cattle Encephalon Glycoside and Ignotin Attenuates Aβ1-42-Mediated Neurotoxicity by Preventing NLRP3 Inflammasome Activation and Modulating Microglial Polarization via TLR4/NF-κB Signaling Pathway. Neurotoxicity research. 2022-10-10. PMID:36214996. |
the nod-like receptor family pyrin domain containing 3 (nlrp3) inflammasome activation-mediated microglial polarization and chronic neuroinflammation play a crucial role in the process of alzheimer's disease (ad). |
2022-10-10 |
2023-08-14 |
mouse |
| Revan Birke Koca-Ünsal, Ahmet Özer Şehirli, Serkan Sayıner, Umut Akso. Relationship of NLRP3 inflammasome with periodontal, endodontic and related systemic diseases. Molecular biology reports. 2022-09-15. PMID:36107371. |
nlrp3 is implicated in several diseases such as diabetes, rheumatoid arthritis, cardiovascular diseases, inflammatory bowel diseases, multiple sclerosis, and alzheimer's disease. |
2022-09-15 |
2023-08-14 |
Not clear |
| Barkha Sharma, Garvit Satija, Anish Madan, Mansi Garg, M Mumtaz Alam, M Shaquiquzzaman, Suruchi Khanna, Prachi Tiwari, Suhel Parvez, Ashif Iqubal, Syed Ehtaishamul Haque, Mohammad Ahmed Kha. Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer's Disease: a Review of Mechanism of Activation, Regulation, and Inhibition. Inflammation. 2022-08-25. PMID:36006570. |
role of nlrp3 inflammasome and its inhibitors as emerging therapeutic drug candidate for alzheimer's disease: a review of mechanism of activation, regulation, and inhibition. |
2022-08-25 |
2023-08-14 |
Not clear |
| Barkha Sharma, Garvit Satija, Anish Madan, Mansi Garg, M Mumtaz Alam, M Shaquiquzzaman, Suruchi Khanna, Prachi Tiwari, Suhel Parvez, Ashif Iqubal, Syed Ehtaishamul Haque, Mohammad Ahmed Kha. Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer's Disease: a Review of Mechanism of Activation, Regulation, and Inhibition. Inflammation. 2022-08-25. PMID:36006570. |
it has been suggested in the literature that suppressing the activity of the nlrp3 inflammasome has substantial potential to prevent, manage, and treat alzheimer's disease. |
2022-08-25 |
2023-08-14 |
Not clear |
| Li Fan, Xie Zhaohong, Wang Xiangxue, Xu Yingying, Zhang Xiao, Zhou Xiaoyan, Yan Jieke, Lai Cha. Melatonin Ameliorates the Progression of Alzheimer's Disease by Inducing TFEB Nuclear Translocation, Promoting Mitophagy, and Regulating NLRP3 Inflammasome Activity. BioMed research international. vol 2022. 2022-08-19. PMID:35983247. |
melatonin ameliorates the progression of alzheimer's disease by inducing tfeb nuclear translocation, promoting mitophagy, and regulating nlrp3 inflammasome activity. |
2022-08-19 |
2023-08-14 |
mouse |
| Wei Li, Jie Liang, Shaohua Li, Luoyang Wang, Shuo Xu, Suli Jiang, Meiying Song, Haining Meng, Dongchang Zhai, Lei Tang, Yanyan Yang, Li Zhang, Bei Zhan. Research progress of targeting NLRP3 inflammasome in peripheral nerve injury and pain. International immunopharmacology. vol 110. 2022-08-18. PMID:35978503. |
numerous studies have shown that the activation of nlrp3 (nod-like receptor family, pyrin domain-containing 3) inflammasome is involved in a various inflammatory response, such as alzheimer's disease, diabetes, nerve damage and other diseases. |
2022-08-18 |
2023-08-14 |
Not clear |
| Xiao-Gang Zhou, Wen-Qiao Qiu, Lu Yu, Rong Pan, Jin-Feng Teng, Zhi-Pei Sang, Betty Yuen-Kwan Law, Ya Zhao, Li Zhang, Lu Yan, Yong Tang, Xiao-Lei Sun, Vincent Kam Wai Wong, Chong-Lin Yu, Jian-Ming Wu, Da-Lian Qin, An-Guo W. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. Inflammation and regeneration. vol 42. issue 1. 2022-08-02. PMID:35918778. |
targeting microglial autophagic degradation of the nlrp3 inflammasome for identification of thonningianin a in alzheimer's disease. |
2022-08-02 |
2023-08-14 |
Not clear |
| Xiao-Gang Zhou, Wen-Qiao Qiu, Lu Yu, Rong Pan, Jin-Feng Teng, Zhi-Pei Sang, Betty Yuen-Kwan Law, Ya Zhao, Li Zhang, Lu Yan, Yong Tang, Xiao-Lei Sun, Vincent Kam Wai Wong, Chong-Lin Yu, Jian-Ming Wu, Da-Lian Qin, An-Guo W. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. Inflammation and regeneration. vol 42. issue 1. 2022-08-02. PMID:35918778. |
nlrp3 inflammasome-mediated neuroinflammation plays a critical role in the pathogenesis and development of alzheimer's disease (ad). |
2022-08-02 |
2023-08-14 |
Not clear |
| Siva Prasad Panda, Yogita Dhurandhar, Mehak Agrawa. The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches. Mitochondrion. 2022-07-16. PMID:35842181. |
the epileptogenesis in patients with alzheimer's disease dementia (add) and parkinson's disease dementia (pdd) is due to involvement of amyloid plaques (aβ), phosphorylated tau (ptau), parkin, nf-kb and nlrp3 inflammasome.microglia, the prime protective and inflammatory cells in the brain exert crosstalk between mitophagy and inflammation. |
2022-07-16 |
2023-08-14 |
Not clear |
| Yueran Cui, Haiyang Yu, Zhongqi Bu, Lulu Wen, Lili Yan, Juan Fen. Focus on the Role of the NLRP3 Inflammasome in Multiple Sclerosis: Pathogenesis, Diagnosis, and Therapeutics. Frontiers in molecular neuroscience. vol 15. 2022-06-13. PMID:35694441. |
among the inflammasomes, the nucleotide-binding oligomerization domain-, leucine-rich repeat- and pyrin domain-containing 3 (nlrp3) inflammasome is well-characterized and contributes to many neurological diseases, such as multiple sclerosis (ms), alzheimer's disease (ad), and ischemic stroke. |
2022-06-13 |
2023-08-14 |
Not clear |
| Jahirul Islam, Jung-Ah Cho, Ju-Yong Kim, Kyung-Sun Park, Young-Jae Koh, Chu Young Chung, Eun-Jae Lee, Soo Jeong Nam, Kyoungyul Lee, Seoung-Heon Kim, Sung-Hye Park, Dong Young Lee, Byeong C Kim, Kyung-Hwa Lee, Seung-Yong Seon. GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease. Frontiers in immunology. vol 13. 2022-04-25. PMID:35464490. |
gpcr19 regulates p2x7r-mediated nlrp3 inflammasomal activation of microglia by amyloid β in a mouse model of alzheimer's disease. |
2022-04-25 |
2023-08-13 |
mouse |
| Tao Yang, Lei Zhang, Yicun Shang, Zhenzhu Zhu, Suxing Jin, Zijian Guo, Xiaoyong Wan. Concurrent suppression of Aβ aggregation and NLRP3 inflammasome activation for treating Alzheimer's disease. Chemical science. vol 13. issue 10. 2022-04-06. PMID:35382471. |
concurrent suppression of aβ aggregation and nlrp3 inflammasome activation for treating alzheimer's disease. |
2022-04-06 |
2023-08-13 |
Not clear |
| Gabriela L Martins, Cláudia N Ferreira, András Palotás, Natália P Rocha, Helton J Rei. Role of oxysterols in the activation of the NLRP3 inflammasome as a potential pharmacological approach in Alzheimer's. Current neuropharmacology. 2022-03-27. PMID:35339182. |
role of oxysterols in the activation of the nlrp3 inflammasome as a potential pharmacological approach in alzheimer's. |
2022-03-27 |
2023-08-13 |
Not clear |
| Gabriela L Martins, Cláudia N Ferreira, András Palotás, Natália P Rocha, Helton J Rei. Role of oxysterols in the activation of the NLRP3 inflammasome as a potential pharmacological approach in Alzheimer's. Current neuropharmacology. 2022-03-27. PMID:35339182. |
as dyslipidemia is a risk factor for dementia, and cholesterol can also activate the inflammasome, a possible link between lipid levels and the nlrp3 inflammasome has been proposed in alzheimer's. |
2022-03-27 |
2023-08-13 |
Not clear |