| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Ulric. [Histochemical representation of acetylcholinesterase in Alzheimer's disease]. Acta histochemica. Supplementband. vol 42. 1992-06-12. PMID:1374916. |
[histochemical representation of acetylcholinesterase in alzheimer's disease]. |
1992-06-12 |
2023-08-11 |
Not clear |
| T G Beach, E G McGee. Senile plaques, amyloid beta-protein, and acetylcholinesterase fibres: laminar distributions in Alzheimer's disease striate cortex. Acta neuropathologica. vol 83. issue 3. 1992-05-06. PMID:1373024. |
senile plaques, amyloid beta-protein, and acetylcholinesterase fibres: laminar distributions in alzheimer's disease striate cortex. |
1992-05-06 |
2023-08-11 |
Not clear |
| P Gomez-Ramos, E J Mufson, M A Mora. Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain. Brain research. vol 569. issue 2. 1992-04-03. PMID:1540829. |
ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and alzheimer's brain. |
1992-04-03 |
2023-08-11 |
Not clear |
| P Gomez-Ramos, E J Mufson, M A Mora. Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain. Brain research. vol 569. issue 2. 1992-04-03. PMID:1540829. |
acetylcholinesterase (ache) histochemistry was used to evaluate the accumulation of this enzyme in senile plaques, neurofibrillary tangles and neuropil threads using light and electron microscopy in alzheimer's disease as well as non-demented aged brains. |
1992-04-03 |
2023-08-11 |
Not clear |
| H A Berman, K Leonar. Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase. Molecular pharmacology. vol 41. issue 2. 1992-03-27. PMID:1538717. |
this paper examines inhibition of acetylcholinesterase (ache) and butyrylcholinesterase (buche) by tetrahydroaminoacridine (tha), an acridine analog under consideration for palliative treatment of alzheimer's dementia. |
1992-03-27 |
2023-08-11 |
Not clear |
| A D Smith, K A Jobst, D S Navaratnam, Z X Shen, J D Priddle, B McDonald, E King, M M Esir. Anomalous acetylcholinesterase in lumbar CSF in Alzheimer's disease. Lancet (London, England). vol 338. issue 8781. 1992-01-15. PMID:1683967. |
anomalous acetylcholinesterase in lumbar csf in alzheimer's disease. |
1992-01-15 |
2023-08-11 |
Not clear |
| D H Small, R D Moir, S J Fuller, S Michaelson, A I Bush, Q X Li, E Milward, C Hilbich, A Weidemann, K Beyreuthe. A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease. Biochemistry. vol 30. issue 44. 1991-12-12. PMID:1718425. |
a protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of alzheimer's disease. |
1991-12-12 |
2023-08-11 |
human |
| M E Appleyard, B McDonal. Reduced adrenal gland acetylcholinesterase activity in Alzheimer's disease. Lancet (London, England). vol 338. issue 8774. 1991-11-21. PMID:1681391. |
reduced adrenal gland acetylcholinesterase activity in alzheimer's disease. |
1991-11-21 |
2023-08-11 |
Not clear |
| O Yasuhara, S Nakamura, I Akiguchi, J Kimura, M Kameyam. [The distribution of senile plaques and acetylcholinesterase staining in the thalamus in dementia of Alzheimer type]. Rinsho shinkeigaku = Clinical neurology. vol 31. issue 4. 1991-11-05. PMID:1717194. |
[the distribution of senile plaques and acetylcholinesterase staining in the thalamus in dementia of alzheimer type]. |
1991-11-05 |
2023-08-11 |
Not clear |
| O Yasuhara, S Nakamura, I Akiguchi, J Kimura, M Kameyam. [The distribution of senile plaques and acetylcholinesterase staining in the thalamus in dementia of Alzheimer type]. Rinsho shinkeigaku = Clinical neurology. vol 31. issue 4. 1991-11-05. PMID:1717194. |
to determine whether the regional distribution of senile plaques is related to the pattern of cholinergic innervation, we studied the distribution of plaques and changes in acetylcholinesterase (ache) reactivity in the thalamus of patients with dementia of alzheimer type (dat). |
1991-11-05 |
2023-08-11 |
Not clear |
| S J Geib, W Tückmantel, A P Kozikowsk. Huperzine A--a potent acetylcholinesterase inhibitor of use in the treatment of Alzheimer's disease. Acta crystallographica. Section C, Crystal structure communications. vol 47 ( Pt 4). 1991-09-11. PMID:1863425. |
huperzine a--a potent acetylcholinesterase inhibitor of use in the treatment of alzheimer's disease. |
1991-09-11 |
2023-08-11 |
Not clear |
| K A Carson, C Geula, M M Mesula. Electron microscopic localization of cholinesterase activity in Alzheimer brain tissue. Brain research. vol 540. issue 1-2. 1991-07-31. PMID:2054612. |
acetylcholinesterase (ache) and butyrylcholinesterase (bche) activity was localized by electron microscopic enzyme cytochemistry in cortex from alzheimer brains and brains from non-demented cases. |
1991-07-31 |
2023-08-11 |
Not clear |
| J P Brandel, E C Hirsch, S Malessa, C Duyckaerts, P Cervera, Y Agi. Differential vulnerability of cholinergic projections to the mediodorsal nucleus of the thalamus in senile dementia of Alzheimer type and progressive supranuclear palsy. Neuroscience. vol 41. issue 1. 1991-07-29. PMID:2057062. |
the cholinergic innervation of the mediodorsal nucleus of the thalamus, which is thought to originate primarily in the laterodorsal tegmental nucleus and the substantia innominata, was studied by acetylcholinesterase histochemistry and immunohistochemistry with a polyclonal antiserum against human choline acetyltransferase on autopsy tissue from eight control subjects, five patients with progressive supranuclear palsy and four patients with senile dementia of alzheimer type. |
1991-07-29 |
2023-08-11 |
human |
| E E Mena, M C Desa. High-affinity [3H]THA (tetrahydroaminoacridine) binding sites in rat brain. Pharmaceutical research. vol 8. issue 2. 1991-05-31. PMID:2023867. |
tetrahydroaminoacridine (tha), an acetylcholinesterase inhibitor that is reported to have significant effects on cognition and memory in alzheimer's disease patients, binds to rat brain membranes in a saturable and reversible manner. |
1991-05-31 |
2023-08-11 |
rat |
| D S Navaratnam, J D Priddle, B McDonald, M M Esiri, J R Robinson, A D Smit. Anomalous molecular form of acetylcholinesterase in cerebrospinal fluid in histologically diagnosed Alzheimer's disease. Lancet (London, England). vol 337. issue 8739. 1991-03-13. PMID:1671469. |
anomalous molecular form of acetylcholinesterase in cerebrospinal fluid in histologically diagnosed alzheimer's disease. |
1991-03-13 |
2023-08-11 |
Not clear |
| D S Navaratnam, J D Priddle, B McDonald, M M Esiri, J R Robinson, A D Smit. Anomalous molecular form of acetylcholinesterase in cerebrospinal fluid in histologically diagnosed Alzheimer's disease. Lancet (London, England). vol 337. issue 8739. 1991-03-13. PMID:1671469. |
the possibility that the different molecular forms of acetylcholinesterase (ache) in cerebrospinal fluid (csf) which can be revealed by isoelectric focusing may reflect changes in ache in pathologically affected neurons in alzheimer's disease was tested in a retrospective study. |
1991-03-13 |
2023-08-11 |
Not clear |
| S Kawakatsu, S Morinobu, M Shinohara, S Totsuka, K Kobash. Acetylcholinesterase activities and monoamine metabolite levels in the cerebrospinal fluid of patients with Alzheimer's disease. Biological psychiatry. vol 28. issue 5. 1990-11-06. PMID:1698467. |
acetylcholinesterase activities and monoamine metabolite levels in the cerebrospinal fluid of patients with alzheimer's disease. |
1990-11-06 |
2023-08-11 |
Not clear |
| P Cumming, P B Reiner, S R Vincen. Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA). Biochemical pharmacology. vol 40. issue 6. 1990-10-22. PMID:2403387. |
9-amino-1,2,3,4-tetrahydroacridine (tha), an inhibitor of acetylcholinesterase, has been proposed as a treatment for alzheimer's disease on the basis of its ability to increase cerebral levels of acetylcholine. |
1990-10-22 |
2023-08-11 |
rat |
| S Nakamura, S Kawashima, S Nakano, T Tsuji, W Arak. Subcellular distribution of acetylcholinesterase in Alzheimer's disease: abnormal localization and solubilization. Journal of neural transmission. Supplementum. vol 30. 1990-10-04. PMID:2391513. |
subcellular distribution of acetylcholinesterase in alzheimer's disease: abnormal localization and solubilization. |
1990-10-04 |
2023-08-11 |
rat |
| G C Siek, L S Katz, E B Fishman, T S Korosi, J K Marqui. Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain. Biological psychiatry. vol 27. issue 6. 1990-05-24. PMID:2322617. |
molecular forms of acetylcholinesterase in subcortical areas of normal and alzheimer disease brain. |
1990-05-24 |
2023-08-11 |
Not clear |