| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iskandar Tamimi, Tomas Ojea, Juan Manuel Sanchez-Siles, Facundo Rojas, Ignacio Martin, Irene Gormaz, Almudena Perez, Marc Stefan Dawid-Milner, Luis Mendez, Faleh Tamim. Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer's disease patients: a case-control study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 27. issue 7. 2012-11-08. PMID:22467182. |
acetylcholinesterase inhibitors and the risk of hip fracture in alzheimer's disease patients: a case-control study. |
2012-11-08 |
2023-08-12 |
Not clear |
| Iskandar Tamimi, Tomas Ojea, Juan Manuel Sanchez-Siles, Facundo Rojas, Ignacio Martin, Irene Gormaz, Almudena Perez, Marc Stefan Dawid-Milner, Luis Mendez, Faleh Tamim. Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer's disease patients: a case-control study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 27. issue 7. 2012-11-08. PMID:22467182. |
accordingly, this study was designed to determine whether the use of acetylcholinesterase inhibitors (acheis), a group of drugs that stimulate ach receptors and are used to treat alzheimer's disease (ad), is associated with a decreased risk of hip fracture in ad patients. |
2012-11-08 |
2023-08-12 |
Not clear |
| Leszek Bidzan, Jakub Grabowski, Beata Dutczak, Mariola Bidza. [Impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in Alzheimer's type dementia]. Psychiatria polska. vol 46. issue 3. 2012-10-25. PMID:23045890. |
[impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in alzheimer's type dementia]. |
2012-10-25 |
2023-08-12 |
Not clear |
| Jonathan Graff-Radford, Bradley F Boeve, Otto Pedraza, Tanis J Ferman, Scott Przybelski, Timothy G Lesnick, Prashanthi Vemuri, Matthew L Senjem, Glenn E Smith, David S Knopman, Val Lowe, Clifford R Jack, Ronald C Petersen, Kejal Kantarc. Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies. Brain : a journal of neurology. vol 135. issue Pt 8. 2012-10-17. PMID:22810436. |
our objective was to determine whether imaging markers of alzheimer's disease-related pathology such as hippocampal volume, brain amyloid-β load on (11)c pittsburgh compound b positron emission tomography predict treatment response to acetylcholinesterase inhibitors in patients with dementia with lewy bodies. |
2012-10-17 |
2023-08-12 |
human |
| Jonathan Graff-Radford, Bradley F Boeve, Otto Pedraza, Tanis J Ferman, Scott Przybelski, Timothy G Lesnick, Prashanthi Vemuri, Matthew L Senjem, Glenn E Smith, David S Knopman, Val Lowe, Clifford R Jack, Ronald C Petersen, Kejal Kantarc. Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies. Brain : a journal of neurology. vol 135. issue Pt 8. 2012-10-17. PMID:22810436. |
we performed a retrospective analysis on consecutive treatment-naive patients with dementia with lewy bodies (n = 54) from the mayo clinic alzheimer's disease research centre who subsequently received acetylcholinesterase inhibitors and underwent magnetic resonance imaging with hippocampal volumetry. |
2012-10-17 |
2023-08-12 |
human |
| Jonathan Graff-Radford, Bradley F Boeve, Otto Pedraza, Tanis J Ferman, Scott Przybelski, Timothy G Lesnick, Prashanthi Vemuri, Matthew L Senjem, Glenn E Smith, David S Knopman, Val Lowe, Clifford R Jack, Ronald C Petersen, Kejal Kantarc. Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies. Brain : a journal of neurology. vol 135. issue Pt 8. 2012-10-17. PMID:22810436. |
patients with dementia with lewy bodies who do not have the imaging features of coexistent alzheimer's disease-related pathology are more likely to cognitively improve with acetylcholinesterase inhibitor treatment. |
2012-10-17 |
2023-08-12 |
human |
| Anthony Klugman, Declan P Naughton, Mokhtar Isaac, Iltaf Shah, Andrea Petroczi, Naji Tabe. Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors. Journal of Alzheimer's disease : JAD. vol 30. issue 3. 2012-10-16. PMID:22451323. |
antioxidant enzymatic activities in alzheimer's disease: the relationship to acetylcholinesterase inhibitors. |
2012-10-16 |
2023-08-12 |
cat |
| Anthony Klugman, Declan P Naughton, Mokhtar Isaac, Iltaf Shah, Andrea Petroczi, Naji Tabe. Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors. Journal of Alzheimer's disease : JAD. vol 30. issue 3. 2012-10-16. PMID:22451323. |
the mode of action of acetylcholinesterase inhibitors (acheis) in alzheimer's disease (ad) is mainly by potentiating neuronal transmission. |
2012-10-16 |
2023-08-12 |
cat |
| Yao Chen, Lei Fang, Sixun Peng, Hong Liao, Jochen Lehmann, Yihua Zhan. Discovery of a novel acetylcholinesterase inhibitor by structure-based virtual screening techniques. Bioorganic & medicinal chemistry letters. vol 22. issue 9. 2012-10-11. PMID:22472693. |
acetylcholinesterase (ache) is considered to be one of the most important targets for the treatment of alzheimer's disease (ad). |
2012-10-11 |
2023-08-12 |
Not clear |
| George D Geromichalos, Fotini N Lamari, Magdalini A Papandreou, Dimitrios T Trafalis, Marigoula Margarity, Athanasios Papageorgiou, Zacharias Sinako. Saffron as a source of novel acetylcholinesterase inhibitors: molecular docking and in vitro enzymatic studies. Journal of agricultural and food chemistry. vol 60. issue 24. 2012-10-10. PMID:22655699. |
inhibitors of acetylcholine breakdown by acetylcholinesterase (ache) constitute the main therapeutic modality for alzheimer's disease. |
2012-10-10 |
2023-08-12 |
Not clear |
| A Ben Hameda, P Táborský, E M Peña-Méndez, J Have. Matrix-assisted laser desorption/ionization mass spectrometry (MALDI TOF MS) study of Huperzine A, a natural anti-Alzheimer's disease product, its derivatization and its detection by highly sensitive laser induced fluorescence (LIF). Talanta. vol 72. issue 2. 2012-10-02. PMID:19071686. |
huperzine a, a reversible acetylcholinesterase inhibitor for the treatment of alzheimer disease (hupa), was studied using an (maldi tof ms) instrument in maldi mode. |
2012-10-02 |
2023-08-12 |
human |
| Lauren Meredith Willis, Barbara Shukitt-Hale, James A Josep. Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain. Genes & nutrition. vol 4. issue 4. 2012-10-02. PMID:19727886. |
despite years of research, pharmacological interventions to treat or forestall the development of alzheimer's disease have primarily focused on enhancing cholinergic transmission, either through increasing acetylcholine (ach) synthesis or inhibition of the acetylcholinesterase enzyme responsible for ach hydrolysis. |
2012-10-02 |
2023-08-12 |
Not clear |
| Eleonora Alfinito, Cecilia Pennetta, Lino Reggian. A network model to correlate conformational change and the impedance spectrum of single proteins. Nanotechnology. vol 19. issue 6. 2012-10-02. PMID:21730695. |
here we focus on two relevant kinds of protein: bovine rhodopsin, prototype of g-protein-coupled-receptor (gpcr) proteins, and the enzyme acetylcholinesterase (ache), whose inhibition is one of the most qualified treatments of alzheimer's disease. |
2012-10-02 |
2023-08-12 |
cattle |
| Faiyaz Ahmed, J N Narendra Sharath Chandra, S Manjunat. Acetylcholine and memory-enhancing activity of Ficus racemosa bark. Pharmacognosy research. vol 3. issue 4. 2012-10-02. PMID:22224047. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder resulting in dementia and enhancement of acetylcholine (ach) levels in brain using acetylcholinesterase inhibitors is one of the most important approaches for the treatment of ad. |
2012-10-02 |
2023-08-12 |
Not clear |
| Kamilla Monteiro dos Santos, Priscila Sant'Ana Gonçalves, Maria José Nunes de Paiva, Guilherme Araújo Lacerd. Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L. Revista da Sociedade Brasileira de Medicina Tropical. vol 44. issue 6. 2012-09-27. PMID:22231255. |
candida (aiton) buch.-ham., and bauhinia ungulata l. a treatment to the alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. |
2012-09-27 |
2023-08-12 |
Not clear |
| L Vezenkov, J Sevalle, D Danalev, T Ivanov, A Bakalova, M Georgieva, F Checle. Galantamine-based hybrid molecules with acetylcholinesterase, butyrylcholinesterase and γ-secretase inhibition activities. Current Alzheimer research. vol 9. issue 5. 2012-09-24. PMID:22211487. |
these compounds we analyzed for their putative inhibitory effect towards acetylcholinesterase, butyrylcholinesterase and γ-secretase, three activities of which could be central to various neurodegenerative pathologies including alzheimer's disease. |
2012-09-24 |
2023-08-12 |
Not clear |
| Yingjun Zhao, Yunshu Wang, Jin Hu, Xian Zhang, Yun-Wu Zhan. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1). The Journal of biological chemistry. vol 287. issue 14. 2012-09-20. PMID:22351782. |
cuta, the mammalian cuta divalent cation tolerance homolog (e. coli), has been proposed to mediate acetylcholinesterase activity and copper homeostasis, which are important in alzheimer disease pathology. |
2012-09-20 |
2023-08-12 |
human |
| Jerald J Nair, Johannes van Stade. Acetylcholinesterase inhibition within the lycorine series of Amaryllidaceae alkaloids. Natural product communications. vol 7. issue 7. 2012-09-20. PMID:22908593. |
in this regard, the alzheimer's drug galanthamine has gained much prominence due to its selective and reversible inhibitory interaction with the enzyme acetylcholinesterase (ache), of significance in the progression of neurodegeneration associated with alzheimer's disease (ad). |
2012-09-20 |
2023-08-12 |
Not clear |
| Kai Wang, Xiaoying Hu, Zhi Wang, Aixia Ya. Classification of acetylcholinesterase inhibitors and decoys by a support vector machine. Combinatorial chemistry & high throughput screening. vol 15. issue 6. 2012-09-19. PMID:22263859. |
acetylcholinesterase has long been considered as a target for alzheimer disease therapy. |
2012-09-19 |
2023-08-12 |
Not clear |
| Vikas Kotagal, Martijn L T M Müller, Daniel I Kaufer, Robert A Koeppe, Nicolaas I Bohne. Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders. Neuroscience letters. vol 514. issue 2. 2012-09-14. PMID:22414859. |
we investigated thalamic cholinergic afferent integrity by measuring ppn-thalamic (ppn-thal) acetylcholinesterase (ache) activity via pet imaging in alzheimer (ad), parkinson disease without dementia (pd), parkinson disease with dementia (pdd) and dementia with lewy bodies (dlb). |
2012-09-14 |
2023-08-12 |
human |