| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Eimar, A Perez Lara, I Tamimi, P Márquez Sánchez, I Gormaz Talavera, F Rojas Tomba, T García de la Oliva, F Tamim. Acetylcholinesterase inhibitors and healing of hip fracture in Alzheimer's disease patients: a retrospective cohort study. Journal of musculoskeletal & neuronal interactions. vol 13. issue 4. 2014-08-11. PMID:24292615. |
this study was designed to assess effects of cholinergic stimulation using acetylcholinesterase inhibitors (acheis), a group of drugs that stimulate cholinergic receptors and are used to treat alzheimer's disease (ad), on healing of hip fractures. |
2014-08-11 |
2023-08-12 |
Not clear |
| Per Johansson, Erik G Almqvist, Jan-Ove Johansson, Niklas Mattsson, Ulf Andreasson, Oskar Hansson, Anders Wallin, Kaj Blennow, Henrik Zetterberg, Johan Svensso. Cerebrospinal fluid (CSF) 25-hydroxyvitamin D concentration and CSF acetylcholinesterase activity are reduced in patients with Alzheimer's disease. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312390. |
cerebrospinal fluid (csf) 25-hydroxyvitamin d concentration and csf acetylcholinesterase activity are reduced in patients with alzheimer's disease. |
2014-08-05 |
2023-08-12 |
Not clear |
| Per Johansson, Erik G Almqvist, Jan-Ove Johansson, Niklas Mattsson, Ulf Andreasson, Oskar Hansson, Anders Wallin, Kaj Blennow, Henrik Zetterberg, Johan Svensso. Cerebrospinal fluid (CSF) 25-hydroxyvitamin D concentration and CSF acetylcholinesterase activity are reduced in patients with Alzheimer's disease. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312390. |
little is known of vitamin d concentration in cerebrospinal fluid (csf) in alzheimer's disease (ad) and its relation with csf acetylcholinesterase (ache) activity, a marker of cholinergic function. |
2014-08-05 |
2023-08-12 |
Not clear |
| Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadi. Identification of potential herbal inhibitor of acetylcholinesterase associated Alzheimer's disorders using molecular docking and molecular dynamics simulation. Biochemistry research international. vol 2014. 2014-07-23. PMID:25054066. |
identification of potential herbal inhibitor of acetylcholinesterase associated alzheimer's disorders using molecular docking and molecular dynamics simulation. |
2014-07-23 |
2023-08-13 |
Not clear |
| Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadi. Identification of potential herbal inhibitor of acetylcholinesterase associated Alzheimer's disorders using molecular docking and molecular dynamics simulation. Biochemistry research international. vol 2014. 2014-07-23. PMID:25054066. |
additionally, acetylcholinesterase (ache) is the target for many alzheimer's dementia drugs which block the function of ache but have some side effects. |
2014-07-23 |
2023-08-13 |
Not clear |
| Ivana Molino, Luisa Colucci, Angiola M Fasanaro, Enea Traini, Francesco Ament. Efficacy of memantine, donepezil, or their association in moderate-severe Alzheimer's disease: a review of clinical trials. TheScientificWorldJournal. vol 2013. 2014-07-17. PMID:24288512. |
acetylcholinesterase (ache)/cholinesterase (che) inhibitors (is) and memantine are licensed for symptomatic treatment of mild-moderate and moderate-severe forms of alzheimer's disease (ad), respectively. |
2014-07-17 |
2023-08-12 |
Not clear |
| Afaf El-Malah, Ehab M Gedawy, Asmaa E Kassab, Rania M Abdel Sala. Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease. Archiv der Pharmazie. vol 347. issue 2. 2014-07-15. PMID:24343873. |
acetylcholinesterase inhibitors (acheis) are used for the treatment of alzheimer's disease (ad). |
2014-07-15 |
2023-08-12 |
Not clear |
| Magdolna Pákáski, Agnes Fehér, Anna Juhász, Gergely Drótos, Orsike Csilla Fazekas, János Kovács, Zoltán Janka, János Kálmá. Serum adipokine levels modified by donepezil treatment in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 38. issue 2. 2014-06-27. PMID:23979024. |
neurotransmitter enhancement therapy with acetylcholinesterase inhibitors (acheis) is a clinically proven approach for patients with alzheimer's disease (ad). |
2014-06-27 |
2023-08-12 |
Not clear |
| Yee-Hui Koay, Alireza Basiri, Vikneswaran Murugaiyah, Kit-Lam Cha. Isocorilagin, a cholinesterase inhibitor from Phyllanthus niruri. Natural product communications. vol 9. issue 4. 2014-06-26. PMID:24868872. |
drugs that have dual inhibition of acetylcholinesterase (ache) and butyrylcholinesterase (bche) produce better clinical efficacy against alzheimer's disease (ad) than those that selectively inhibit one enzyme. |
2014-06-26 |
2023-08-13 |
Not clear |
| Amy Easton, Sethu Sankaranarayanan, An Tanghe, Dick Terwel, Alan X Lin, Nina Hoque, Clotilde Bourin, Huidong Gu, Michael Ahlijanian, Linda Bristo. Effects of sub-chronic donepezil on brain Abeta and cognition in a mouse model of Alzheimer's disease. Psychopharmacology. vol 230. issue 2. 2014-06-23. PMID:23783773. |
acetylcholinesterase inhibitors (acheis) are approved to treat the symptoms of mild to moderate alzheimer's disease by restoring acetylcholine levels at synapses where the neurotransmitter has been depleted due to neurodegeneration. |
2014-06-23 |
2023-08-12 |
mouse |
| George T Grossber. Cholinesterase inhibitors for the treatment of Alzheimer's disease:: getting on and staying on. Current therapeutic research, clinical and experimental. vol 64. issue 4. 2014-06-19. PMID:24944370. |
cholinesterase (che) inhibitors currently used in the treatment of alzheimer's disease (ad) are the acetylcholinesterase (ache)-selective inhibitors, donepezil and galantamine, and the dual ache and butyrylcholinesterase (buche) inhibitor, rivastigmine. |
2014-06-19 |
2023-08-13 |
Not clear |
| F M Garlich, K Balakrishnan, S K Shah, M A Howland, J Fong, L S Nelso. Prolonged altered mental status and bradycardia following pediatric donepezil ingestion. Clinical toxicology (Philadelphia, Pa.). vol 52. issue 4. 2014-06-17. PMID:24735001. |
donepezil is a centrally-acting, reversible acetylcholinesterase inhibitor that is used in the treatment of alzheimer disease. |
2014-06-17 |
2023-08-13 |
Not clear |
| Stefania Butini, Margherita Brindisi, Simone Brogi, Samuele Maramai, Egeria Guarino, Alessandro Panico, Ashima Saxena, Ved Chauhan, Raffaella Colombo, Laura Verga, Ersilia De Lorenzi, Manuela Bartolini, Vincenza Andrisano, Ettore Novellino, Giuseppe Campiani, Sandra Gemm. Multifunctional cholinesterase and amyloid Beta fibrillization modulators. Synthesis and biological investigation. ACS medicinal chemistry letters. vol 4. issue 12. 2014-06-05. PMID:24900626. |
in order to identify novel alzheimer's modifying pharmacological tools, we developed bis-tacrines bearing a peptide moiety for specific interference with surface sites of human acetylcholinesterase (hache) binding amyloid-beta (aβ). |
2014-06-05 |
2023-08-13 |
human |
| Kenia Lourenço Vanzolini, Zhengjin Jiang, Xiaoqi Zhang, Lucas Campos Curcino Vieira, Arlene Gonçalvez Corrêa, Carmen Lucia Cardoso, Quezia Bezerra Cass, Ruin Moadde. Acetylcholinesterase immobilized capillary reactors coupled to protein coated magnetic beads: a new tool for plant extract ligand screening. Talanta. vol 116. 2014-06-03. PMID:24148457. |
in this work the selected target was the enzyme acetylcholinesterase (ache), which acts on the central nervous system and is a validated target for the treatment of alzheimer's disease, as well as for new insecticides. |
2014-06-03 |
2023-08-12 |
Not clear |
| Hoo Rim Song, Young Sup Woo, Hee-Ryung Wang, Tae-Youn Jun, Won-Myong Bah. Effect of the timing of acetylcholinesterase inhibitor ingestion on sleep. International clinical psychopharmacology. vol 28. issue 6. 2014-05-08. PMID:23948729. |
these results suggest that taking acetylcholinesterase inhibitors in the morning can improve the sleep states of patients with alzheimer's disease. |
2014-05-08 |
2023-08-12 |
Not clear |
| Ganiyu Oboh, Ayodele Jacobson Akinyemi, Adedayo Oluwaseun Ademiluyi, Fatai Olumide Bell. Inhibitory effect of some tropical green leafy vegetables on key enzymes linked to Alzheimer's disease and some pro-oxidant induced lipid peroxidation in rats' brain. Journal of food science and technology. vol 51. issue 5. 2014-05-07. PMID:24803694. |
this study sought to investigate the inhibitory effect of some commonly consumed nigerian green leafy vegetables (raw and blanched) on acetylcholinesterase and butyrylcholinesterase (key enzyme linked to alzheimer's disease) activities and some pro-oxidants (feso4, sodium nitroprusside and quinolinic acid) induced lipid peroxidation in rat brain in vitro. |
2014-05-07 |
2023-08-13 |
rat |
| José C J M D S Menezes, José A S Cavaleiro, M Rosário M Domingue. Structural analysis of 2-arylidene-1-indanone derivatives by electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. vol 27. issue 21. 2014-05-06. PMID:24097403. |
2-arylidene-4-methoxy (or hydroxy)-7-methyl-1-indanone derivatives inspired from donepezil, the current drug used for the treatment of alzheimer's disease as inhibitor of acetylcholinesterase (ache), were studied for the first time by electrospray ionization mass spectrometry (esi-ms) and tandem mass spectrometry (ms/ms). |
2014-05-06 |
2023-08-12 |
Not clear |
| Cassandra Richardson, Paul R Gard, Anthony Klugman, Mokhtar Isaac, Naji Tabe. Blood pro-inflammatory cytokines in Alzheimer's disease in relation to the use of acetylcholinesterase inhibitors. International journal of geriatric psychiatry. vol 28. issue 12. 2014-05-02. PMID:23585364. |
blood pro-inflammatory cytokines in alzheimer's disease in relation to the use of acetylcholinesterase inhibitors. |
2014-05-02 |
2023-08-12 |
Not clear |
| b' Biljana Bo\\xc5\\xbein, Neboj\\xc5\\xa1a Kladar, Nevena Gruji\\xc4\\x87, Goran Ana\\xc4\\x8dkov, Isidora Samojlik, Neda Gavari\\xc4\\x87, Branislava Sr\\xc4\\x91enovi\\xc4\\x87 Coni\\xc4\\x8. Impact of origin and biological source on chemical composition, anticholinesterase and antioxidant properties of some St. John\'s wort species (Hypericum spp., Hypericaceae) from the Central Balkans. Molecules (Basel, Switzerland). vol 18. issue 10. 2014-04-22. PMID:24071982.' |
since all of the investigated species have shown prominent inhibition of acetylcholinesterase in vitro activity, they could be further investigated as potential substances in preventing of alzheimer's disease. |
2014-04-22 |
2023-08-12 |
Not clear |
| Chris G Parsons, Wojciech Danysz, Andrzej Dekundy, Irena Pult. Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease. Neurotoxicity research. vol 24. issue 3. 2014-04-08. PMID:23657927. |
this review describes the preclinical mechanisms that may underlie the increased therapeutic benefit of combination therapy-with the n-methyl-d-aspartate receptor antagonist, memantine, and an acetylcholinesterase inhibitor (achei)-for the treatment of alzheimer's disease (ad). |
2014-04-08 |
2023-08-12 |
Not clear |