| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eugene Lin, Shih-Jen Tsai, Po-Hsiu Kuo, Yu-Li Liu, Albert C Yang, Chung-Feng Ka. Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. Oncotarget. vol 8. issue 15. 2018-03-05. PMID:28199971. |
genome-wide association studies and meta-analyses implicated that increased risk of developing alzheimer's diseases (ad) has been associated with the abca7, apoe, bin1, cass4, cd2ap, cd33, celf1, clu, cr1, dsg2, epha1, fermt2, hla-drb1, hla-drb4, inpp5d, mef2c, ms4a4a, ms4a4e, ms4a6e, nme8, picalm, pld3, ptk2b, rin3, slc24a4, sorl1, and zcwpw1 genes. |
2018-03-05 |
2023-08-13 |
human |
| Kiyohiro Yamazaki, Yuta Yoshino, Takaaki Mori, Taku Yoshida, Yuki Ozaki, Tomoko Sao, Yoko Mori, Shinichiro Ochi, Jun-Ichi Iga, Shu-Ichi Uen. Gene Expression and Methylation Analysis of ABCA7 in Patients with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 57. issue 1. 2018-02-26. PMID:28222527. |
gene expression and methylation analysis of abca7 in patients with alzheimer's disease. |
2018-02-26 |
2023-08-13 |
Not clear |
| Arne De Roeck, Tobi Van den Bossche, Julie van der Zee, Jan Verheijen, Wouter De Coster, Jasper Van Dongen, Lubina Dillen, Yalda Baradaran-Heravi, Bavo Heeman, Raquel Sanchez-Valle, Albert Lladó, Benedetta Nacmias, Sandro Sorbi, Ellen Gelpi, Oriol Grau-Rivera, Estrella Gómez-Tortosa, Pau Pastor, Sara Ortega-Cubero, Maria A Pastor, Caroline Graff, Håkan Thonberg, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Maria Rosário Almeida, Isabel Santana, Janine Diehl-Schmid, Panagiotis Alexopoulos, Jordi Clarimon, Alberto Lleó, Juan Fortea, Magda Tsolaki, Maria Koutroumani, Radoslav Matěj, Zdenek Rohan, Peter De Deyn, Sebastiaan Engelborghs, Patrick Cras, Christine Van Broeckhoven, Kristel Sleeger. Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease. Acta neuropathologica. vol 134. issue 3. 2018-02-07. PMID:28447221. |
deleterious abca7 mutations and transcript rescue mechanisms in early onset alzheimer's disease. |
2018-02-07 |
2023-08-13 |
Not clear |
| Arne De Roeck, Tobi Van den Bossche, Julie van der Zee, Jan Verheijen, Wouter De Coster, Jasper Van Dongen, Lubina Dillen, Yalda Baradaran-Heravi, Bavo Heeman, Raquel Sanchez-Valle, Albert Lladó, Benedetta Nacmias, Sandro Sorbi, Ellen Gelpi, Oriol Grau-Rivera, Estrella Gómez-Tortosa, Pau Pastor, Sara Ortega-Cubero, Maria A Pastor, Caroline Graff, Håkan Thonberg, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Maria Rosário Almeida, Isabel Santana, Janine Diehl-Schmid, Panagiotis Alexopoulos, Jordi Clarimon, Alberto Lleó, Juan Fortea, Magda Tsolaki, Maria Koutroumani, Radoslav Matěj, Zdenek Rohan, Peter De Deyn, Sebastiaan Engelborghs, Patrick Cras, Christine Van Broeckhoven, Kristel Sleeger. Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease. Acta neuropathologica. vol 134. issue 3. 2018-02-07. PMID:28447221. |
premature termination codon (ptc) mutations in the atp-binding cassette, sub-family a, member 7 gene (abca7) have recently been identified as intermediate-to-high penetrant risk factor for late-onset alzheimer's disease (load). |
2018-02-07 |
2023-08-13 |
Not clear |
| Céline Bellenguez, Camille Charbonnier, Benjamin Grenier-Boley, Olivier Quenez, Kilan Le Guennec, Gaël Nicolas, Ganesh Chauhan, David Wallon, Stéphane Rousseau, Anne Claire Richard, Anne Boland, Guillaume Bourque, Hans Markus Munter, Robert Olaso, Vincent Meyer, Adeline Rollin-Sillaire, Florence Pasquier, Luc Letenneur, Richard Redon, Jean-François Dartigues, Christophe Tzourio, Thierry Frebourg, Mark Lathrop, Jean-François Deleuze, Didier Hannequin, Emmanuelle Genin, Philippe Amouyel, Stéphanie Debette, Jean-Charles Lambert, Dominique Campio. Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls. Neurobiology of aging. vol 59. 2018-01-08. PMID:28789839. |
contribution to alzheimer's disease risk of rare variants in trem2, sorl1, and abca7 in 1779 cases and 1273 controls. |
2018-01-08 |
2023-08-13 |
Not clear |
| Maiko Tomioka, Yoshinobu Toda, Noralyn B Mañucat, Hiroyasu Akatsu, Manabu Fukumoto, Nozomu Kono, Hiroyuki Arai, Noriyuki Kioka, Kazumitsu Ued. Lysophosphatidylcholine export by human ABCA7. Biochimica et biophysica acta. Molecular and cell biology of lipids. vol 1862. issue 7. 2017-10-19. PMID:28373057. |
the atp-binding cassette transporter a7 (abca7), which is highly expressed in the brain, is associated with the pathogenesis of alzheimer's disease (ad). |
2017-10-19 |
2023-08-13 |
human |
| Celeste Sassi, Michael A Nalls, Perry G Ridge, Jesse R Gibbs, Jinhui Ding, Michelle K Lupton, Claire Troakes, Katie Lunnon, Safa Al-Sarraj, Kristelle S Brown, Christopher Medway, Naomi Clement, Jenny Lord, James Turton, Jose Bras, Maria R Almeida, Henne Holstege, Eva Louwersheimer, Wiesje M van der Flier, Philip Scheltens, John C Van Swieten, Isabel Santana, Catarina Oliveira, Kevin Morgan, John F Powell, John S Kauwe, Carlos Cruchaga, Alison M Goate, Andrew B Singleton, Rita Guerreiro, John Hard. ABCA7 p.G215S as potential protective factor for Alzheimer's disease. Neurobiology of aging. vol 46. 2017-09-28. PMID:27289440. |
abca7 p.g215s as potential protective factor for alzheimer's disease. |
2017-09-28 |
2023-08-13 |
Not clear |
| Diana Jennifer Moreno, Susana Ruiz, Ángela Ríos, Francisco Lopera, Henry Ostos, Marc Via, Gabriel Bedoy. Association of GWAS Top Genes With Late-Onset Alzheimer's Disease in Colombian Population. American journal of Alzheimer's disease and other dementias. vol 32. issue 1. 2017-09-22. PMID:28084078. |
the association of variants in clu, cr1, picalm, bin1, abca7, and cd33 genes with late-onset alzheimer's disease (load) was evaluated and confirmed through genome-wide association study. |
2017-09-22 |
2023-08-13 |
Not clear |
| Henna Martiskainen, Sanna-Kaisa Herukka, Alena Stančáková, Jussi Paananen, Hilkka Soininen, Johanna Kuusisto, Markku Laakso, Mikko Hiltune. Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers. Annals of neurology. vol 82. issue 1. 2017-08-22. PMID:28556232. |
we investigated the association of alzheimer's disease (ad)-related rare variants app a673t and abca7 rs200538373-c with the levels of β-amyloid (aβ) and parameters of metabolic and cardiovascular health in a population-based cohort of healthy middle-aged and elderly men. |
2017-08-22 |
2023-08-13 |
Not clear |
| Mengqian Li, Yefeng Yuan, Bo Hu, Lei W. Study on Lentivirus-Mediated ABCA7 Improves Neurocognitive Function and Related Mechanisms in the C57BL/6 Mouse Model of Alzheimer's Disease. Journal of molecular neuroscience : MN. vol 61. issue 4. 2017-07-24. PMID:28124230. |
study on lentivirus-mediated abca7 improves neurocognitive function and related mechanisms in the c57bl/6 mouse model of alzheimer's disease. |
2017-07-24 |
2023-08-13 |
mouse |
| Mengqian Li, Yefeng Yuan, Bo Hu, Lei W. Study on Lentivirus-Mediated ABCA7 Improves Neurocognitive Function and Related Mechanisms in the C57BL/6 Mouse Model of Alzheimer's Disease. Journal of molecular neuroscience : MN. vol 61. issue 4. 2017-07-24. PMID:28124230. |
atp-binding cassette transporter a7 (abca7) is expressed in the hippocampus and cortex of the brain and was confirmed to be involved in the development of alzheimer's disease (ad). |
2017-07-24 |
2023-08-13 |
mouse |
| Kilan Le Guennec, Gaël Nicolas, Olivier Quenez, Camille Charbonnier, David Wallon, Céline Bellenguez, Benjamin Grenier-Boley, Stéphane Rousseau, Anne-Claire Richard, Anne Rovelet-Lecrux, Delphine Bacq, Jean-Guillaume Garnier, Robert Olaso, Anne Boland, Vincent Meyer, Jean-François Deleuze, Philippe Amouyel, Hans Markus Munter, Guillaume Bourque, Mark Lathrop, Thierry Frebourg, Richard Redon, Luc Letenneur, Jean-François Dartigues, Florence Pasquier, Adeline Rollin-Sillaire, Emmanuelle Génin, Jean-Charles Lambert, Didier Hannequin, Dominique Campio. ABCA7 rare variants and Alzheimer disease risk. Neurology. vol 86. issue 23. 2017-05-08. PMID:27037229. |
abca7 rare variants and alzheimer disease risk. |
2017-05-08 |
2023-08-13 |
Not clear |
| Kilan Le Guennec, Gaël Nicolas, Olivier Quenez, Camille Charbonnier, David Wallon, Céline Bellenguez, Benjamin Grenier-Boley, Stéphane Rousseau, Anne-Claire Richard, Anne Rovelet-Lecrux, Delphine Bacq, Jean-Guillaume Garnier, Robert Olaso, Anne Boland, Vincent Meyer, Jean-François Deleuze, Philippe Amouyel, Hans Markus Munter, Guillaume Bourque, Mark Lathrop, Thierry Frebourg, Richard Redon, Luc Letenneur, Jean-François Dartigues, Florence Pasquier, Adeline Rollin-Sillaire, Emmanuelle Génin, Jean-Charles Lambert, Didier Hannequin, Dominique Campio. ABCA7 rare variants and Alzheimer disease risk. Neurology. vol 86. issue 23. 2017-05-08. PMID:27037229. |
to study the association between abca7 rare coding variants and alzheimer disease (ad) in a case-control setting. |
2017-05-08 |
2023-08-13 |
Not clear |
| Tobi Van den Bossche, Kristel Sleegers, Elise Cuyvers, Sebastiaan Engelborghs, Anne Sieben, Arne De Roeck, Caroline Van Cauwenberghe, Steven Vermeulen, Marleen Van den Broeck, Annelies Laureys, Karin Peeters, Maria Mattheijssens, Mathieu Vandenbulcke, Rik Vandenberghe, Jean-Jacques Martin, Peter P De Deyn, Patrick Cras, Christine Van Broeckhove. Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation. Neurology. vol 86. issue 23. 2017-05-08. PMID:27037232. |
phenotypic characteristics of alzheimer patients carrying an abca7 mutation. |
2017-05-08 |
2023-08-13 |
Not clear |
| Tobi Van den Bossche, Kristel Sleegers, Elise Cuyvers, Sebastiaan Engelborghs, Anne Sieben, Arne De Roeck, Caroline Van Cauwenberghe, Steven Vermeulen, Marleen Van den Broeck, Annelies Laureys, Karin Peeters, Maria Mattheijssens, Mathieu Vandenbulcke, Rik Vandenberghe, Jean-Jacques Martin, Peter P De Deyn, Patrick Cras, Christine Van Broeckhove. Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation. Neurology. vol 86. issue 23. 2017-05-08. PMID:27037232. |
to generate a clinical and pathologic phenotype of patients carrying rare loss-of-function mutations in abca7, identified in a belgian alzheimer patient cohort and in an autosomal dominant family. |
2017-05-08 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Yu Wan, Hui-Fu Wang, Fu-Rong Sun, Xiao-Ke Hao, Meng-Shan Tan, Chen-Chen Tan, Dao-Qiang Zhang, Lan Tan, Jin-Tai Y. ABCA7 Genotypes Confer Alzheimer's Disease Risk by Modulating Amyloid-β Pathology. Journal of Alzheimer's disease : JAD. vol 52. issue 2. 2017-01-30. PMID:27003212. |
abca7 genotypes confer alzheimer's disease risk by modulating amyloid-β pathology. |
2017-01-30 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Yu Wan, Hui-Fu Wang, Fu-Rong Sun, Xiao-Ke Hao, Meng-Shan Tan, Chen-Chen Tan, Dao-Qiang Zhang, Lan Tan, Jin-Tai Y. ABCA7 Genotypes Confer Alzheimer's Disease Risk by Modulating Amyloid-β Pathology. Journal of Alzheimer's disease : JAD. vol 52. issue 2. 2017-01-30. PMID:27003212. |
abca7 gene has been identified as a strong genetic locus for alzheimer's disease (ad) susceptibility in genome wide association studies (gwas). |
2017-01-30 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Yu Wan, Hui-Fu Wang, Fu-Rong Sun, Xiao-Ke Hao, Meng-Shan Tan, Chen-Chen Tan, Dao-Qiang Zhang, Lan Tan, Jin-Tai Y. ABCA7 Genotypes Confer Alzheimer's Disease Risk by Modulating Amyloid-β Pathology. Journal of Alzheimer's disease : JAD. vol 52. issue 2. 2017-01-30. PMID:27003212. |
using tagger methods, we extracted 15 targeted abca7 loci to investigate their associations with cerebrospinal fluid (csf) and neuroimaging markers in alzheimer's disease neuroimaging initiative (adni) dataset. |
2017-01-30 |
2023-08-13 |
Not clear |
| Jasmine Nettiksimmons, Gregory Tranah, Daniel S Evans, Jennifer S Yokoyama, Kristine Yaff. Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. Age (Dordrecht, Netherlands). vol 38. issue 2. 2016-12-20. PMID:27005436. |
single nucleotide polymorphisms (snps) in and near abca7, bin1, cass4, cd2ap, cd33, celf1, clu, complement receptor 1 (cr1), epha1, exoc3l2, fermt2, hla cluster (drb5-dqa), inpp5d, mef2c, ms4a cluster (ms4a3-ms4a6e), nme8, picalm, ptk2b, slc24a4, sorl1, and zcwpw1 have been associated with alzheimer's disease (ad) in large meta-analyses. |
2016-12-20 |
2023-08-13 |
Not clear |
| Timothy J Hohman, Jessica N Cooke-Bailey, Christiane Reitz, Gyungah Jun, Adam Naj, Gary W Beecham, Zhi Liu, Regina M Carney, Jeffrey M Vance, Michael L Cuccaro, Ruchita Rajbhandary, Badri Narayan Vardarajan, Li-San Wang, Otto Valladares, Chiao-Feng Lin, Eric B Larson, Neill R Graff-Radford, Denis Evans, Philip L De Jager, Paul K Crane, Joseph D Buxbaum, Jill R Murrell, Towfique Raj, Nilufer Ertekin-Taner, Mark W Logue, Clinton T Baldwin, Robert C Green, Lisa L Barnes, Laura B Cantwell, M Daniele Fallin, Rodney C P Go, Patrick Griffith, Thomas O Obisesan, Jennifer J Manly, Kathryn L Lunetta, M Ilyas Kamboh, Oscar L Lopez, David A Bennett, John Hardy, Hugh C Hendrie, Kathleen S Hall, Alison M Goate, Rosalyn Lang, Goldie S Byrd, Walter A Kukull, Tatiana M Foroud, Lindsay A Farrer, Eden R Martin, Margaret A Pericak-Vance, Gerard D Schellenberg, Richard Mayeux, Jonathan L Haines, Tricia A Thornton-Well. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 3. 2016-12-15. PMID:26092349. |
recently, the largest genome-wide association study in aas to date confirmed that six of the alzheimer's disease (ad)-related genetic variants originally discovered in ea cohorts are also risk variants in aa; however, the risk attributable to many of the loci (e.g., apoe, abca7) differed substantially from previous studies in ea. |
2016-12-15 |
2023-08-13 |
Not clear |