| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sumiko Abe-Dohmae, Shinji Yokoyam. ABCA7 links sterol metabolism to the host defense system: Molecular background for potential management measure of Alzheimer's disease. Gene. vol 768. 2021-01-18. PMID:33221536. |
accordingly, modulation of abca7 activity by manipulating cholesterol metabolism may open a new path for management of alzheimer's disease. |
2021-01-18 |
2023-08-13 |
Not clear |
| Sonja Blumenau, Marco Foddis, Susanne Müller, Manuel Holtgrewe, Kajetan Bentele, Daniel Berchtold, Dieter Beule, Ulrich Dirnagl, Celeste Sass. Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:32345996. |
therefore we used taqman genotyping, exome and rna sequencing to investigate alzheimer's disease known pathogenic variants and pathways: apoe ε4 allele, app-aβ metabolism and late-onset alzheimer's disease main genome-wide association loci (apoe, bin1, cd33, ms4a6a, cd2ap, picalm, clu, cr1, epha1, abca7) in 96 early-onset small vessel ischemic disease caucasian patients and 368 elderly neuropathologically proven controls (hex database) and in a mouse model of cerebral hypoperfusion. |
2020-11-30 |
2023-08-13 |
mouse |
| Mahnaz Talebi, Azra Delpak, Mohamad Khalaj-Kondori, Saeed Sadigh-Eteghad, Malihe Talebi, Elham Mehdizadeh, Alireza Majd. ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer's Disease. Journal of molecular neuroscience : MN. vol 70. issue 2. 2020-11-19. PMID:31659653. |
abca7 and epha1 genes polymorphisms in late-onset alzheimer's disease. |
2020-11-19 |
2023-08-13 |
human |
| Risa Mitsumori, Kazuya Sakaguchi, Daichi Shigemizu, Taiki Mori, Shintaro Akiyama, Kouichi Ozaki, Shumpei Niida, Nobuyoshi Shimod. Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer's disease patients. PloS one. vol 15. issue 9. 2020-11-05. PMID:32991610. |
the aim of the present study was to (1) investigate the relationship between late-onset alzheimer's disease (ad) and dna methylation levels in six of the top seven ad-associated genes identified through a meta-analysis of recent genome wide association studies, apoe, bin1, picalm, cr1, clu, and abca7, in blood, and (2) examine its applicability to the diagnosis of ad. |
2020-11-05 |
2023-08-13 |
human |
| Morgane Lacour, Olivier Quenez, Anne Rovelet-Lecrux, Bruno Salomon, Stephane Rousseau, Anne-Claire Richard, Muriel Quillard-Muraine, Florence Pasquier, Adeline Rollin-Sillaire, Olivier Martinaud, Aline Zarea, Vincent de la Sayette, Claire Boutoleau-Bretonniere, Frédérique Etcharry-Bouyx, Valérie Chauviré, Marie Sarazin, Isabelle le Ber, Stéphane Epelbaum, Thérèse Jonveaux, Olivier Rouaud, Mathieu Ceccaldi, Olivier Godefroy, Maite Formaglio, Bernard Croisile, Sophie Auriacombe, Eloi Magnin, Mathilde Sauvée, Cecilia Marelli, Audrey Gabelle, Jeremie Pariente, Claire Paquet, Anne Boland, Jean-François Deleuze, Dominique Campion, Didier Hannequin, Gael Nicolas, David Wallo. Causative Mutations and Genetic Risk Factors in Sporadic Early Onset Alzheimer's Disease Before 51 Years. Journal of Alzheimer's disease : JAD. vol 71. issue 1. 2020-10-13. PMID:31381512. |
pathogenic variants in the autosomal dominant genes psen1, psen2, or app, apoe4 alleles, and rare variants within trem2, sorl1, and abca7 contribute to early-onset alzheimer's disease (eoad). |
2020-10-13 |
2023-08-13 |
Not clear |
| Fang-Chen Ma, Yu Zong, Hui-Fu Wang, Jie-Qiong Li, Xi-Peng Cao, Lan Ta. ABCA7 genotype altered Aβ levels in cerebrospinal fluid in Alzheimer's disease without dementia. Annals of translational medicine. vol 6. issue 22. 2020-10-01. PMID:30596067. |
abca7 genotype altered aβ levels in cerebrospinal fluid in alzheimer's disease without dementia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Fang-Chen Ma, Yu Zong, Hui-Fu Wang, Jie-Qiong Li, Xi-Peng Cao, Lan Ta. ABCA7 genotype altered Aβ levels in cerebrospinal fluid in Alzheimer's disease without dementia. Annals of translational medicine. vol 6. issue 22. 2020-10-01. PMID:30596067. |
atp-binding cassette transporter a7 (abca7) rs3764650 has been identified to be a susceptibility locus for alzheimer's disease (ad), but its role in cerebrospinal fluid (csf) proteins was still unclear. |
2020-10-01 |
2023-08-13 |
Not clear |
| Chelsie N Berg, Neha Sinha, Mark A Gluc. ABCA7 Risk Genotype Diminishes the Neuroprotective Value of Aerobic Fitness in Healthy Older African Americans. Frontiers in aging neuroscience. vol 11. 2020-10-01. PMID:31024289. |
although the association of abca7 risk variants with alzheimer's disease (ad) has been established worldwide, its effect size on the relative odds of being diagnosed with ad is significantly higher in african americans. |
2020-10-01 |
2023-08-13 |
Not clear |
| Chelsie N Berg, Neha Sinha, Mark A Gluc. The Effects of APOE and ABCA7 on Cognitive Function and Alzheimer's Disease Risk in African Americans: A Focused Mini Review. Frontiers in human neuroscience. vol 13. 2020-10-01. PMID:31749691. |
the effects of apoe and abca7 on cognitive function and alzheimer's disease risk in african americans: a focused mini review. |
2020-10-01 |
2023-08-13 |
Not clear |
| Surabhi Bhatia, YuHong Fu, Jen-Hsiang T Hsiao, Glenda M Halliday, Woojin Scott Ki. Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels. Journal of Alzheimer's disease reports. vol 1. issue 1. 2020-09-30. PMID:30480241. |
deletion of alzheimer's disease risk gene abca7 alters white adipose tissue development and leptin levels. |
2020-09-30 |
2023-08-13 |
mouse |
| Surabhi Bhatia, YuHong Fu, Jen-Hsiang T Hsiao, Glenda M Halliday, Woojin Scott Ki. Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels. Journal of Alzheimer's disease reports. vol 1. issue 1. 2020-09-30. PMID:30480241. |
atp-binding cassette a7 (abca7) is a genetic risk factor for late-onset alzheimer's disease (ad). |
2020-09-30 |
2023-08-13 |
mouse |
| Tomonori Aikawa, Marie-Louise Holm, Takahisa Kanekiy. ABCA7 and Pathogenic Pathways of Alzheimer's Disease. Brain sciences. vol 8. issue 2. 2020-09-29. PMID:29401741. |
abca7 and pathogenic pathways of alzheimer's disease. |
2020-09-29 |
2023-08-13 |
human |
| Tomonori Aikawa, Marie-Louise Holm, Takahisa Kanekiy. ABCA7 and Pathogenic Pathways of Alzheimer's Disease. Brain sciences. vol 8. issue 2. 2020-09-29. PMID:29401741. |
while abca7 is expressed in a variety of tissues/organs, including the brain, recent genome-wide association studies (gwas) have identified abca7 gene variants as susceptibility loci for late-onset alzheimer's disease (ad). |
2020-09-29 |
2023-08-13 |
human |
| Alexei A Surguchev, Andrei Surgucho. ABCA7-A Member of the ABC Transporter Family in Healthy and Ailing Brain. Brain sciences. vol 10. issue 2. 2020-09-28. PMID:32098344. |
the role of abca7 in alzheimer's disease (ad) was discovered less than ten years ago when meta-analyses provided evidence that rs3764650 is a new ad susceptibility locus. |
2020-09-28 |
2023-08-13 |
human |
| Alexei A Surguchev, Andrei Surgucho. ABCA7-A Member of the ABC Transporter Family in Healthy and Ailing Brain. Brain sciences. vol 10. issue 2. 2020-09-28. PMID:32098344. |
an interesting, up-to-date review article "abca7 and pathogenic pathways of alzheimer's disease" by aikawa et al. |
2020-09-28 |
2023-08-13 |
human |
| Ya-Ting Chang, Shih-Wei Hsu, Shu-Hua Huang, Chi-Wei Huang, Wen-Neng Chang, Chia-Yi Lien, Jun-Jun Lee, Chen-Chang Lee, Chiung-Chih Chan. ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer's disease. Alzheimer's research & therapy. vol 11. issue 1. 2020-08-06. PMID:31831047. |
abca7 polymorphisms correlate with memory impairment and default mode network in patients with apoeε4-associated alzheimer's disease. |
2020-08-06 |
2023-08-13 |
Not clear |
| Ya-Ting Chang, Shih-Wei Hsu, Shu-Hua Huang, Chi-Wei Huang, Wen-Neng Chang, Chia-Yi Lien, Jun-Jun Lee, Chen-Chang Lee, Chiung-Chih Chan. ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer's disease. Alzheimer's research & therapy. vol 11. issue 1. 2020-08-06. PMID:31831047. |
since both apoe and abca7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we aimed to investigate the effect of the apoe-abca7 interaction on default mode network in alzheimer's disease. |
2020-08-06 |
2023-08-13 |
Not clear |
| Kristel Sleeger. Expression of ABCA7 in Alzheimer's disease. Acta neuropathologica. vol 139. issue 5. 2020-07-27. PMID:32112170. |
expression of abca7 in alzheimer's disease. |
2020-07-27 |
2023-08-13 |
Not clear |
| Arne De Roeck, Christine Van Broeckhoven, Kristel Sleeger. The role of ABCA7 in Alzheimer's disease: evidence from genomics, transcriptomics and methylomics. Acta neuropathologica. vol 138. issue 2. 2020-07-20. PMID:30903345. |
the role of abca7 in alzheimer's disease: evidence from genomics, transcriptomics and methylomics. |
2020-07-20 |
2023-08-13 |
human |
| Arne De Roeck, Christine Van Broeckhoven, Kristel Sleeger. The role of ABCA7 in Alzheimer's disease: evidence from genomics, transcriptomics and methylomics. Acta neuropathologica. vol 138. issue 2. 2020-07-20. PMID:30903345. |
genome-wide association studies (gwas) originally identified atp-binding cassette, sub-family a, member 7 (abca7), as a novel risk gene of alzheimer's disease (ad). |
2020-07-20 |
2023-08-13 |
human |