| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liene Bossaerts, Elisabeth Hens, Rita Cacace, Bernard J Hanseeuw, Rik Vandenberghe, Patrick Cras, Peter Paul De Deyn, Sebastiaan Engelborghs, Christine Van Broeckhove. Rare missense mutations and compound heterozygous mutations in ABCA7 contribute to Alzheimer's disease in Belgian patients. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108979. |
initially, abca7 was associated with alzheimer's disease (ad) in large genome-wide association studies. |
2022-02-03 |
2023-08-13 |
Not clear |
| Henne Holstege, Marc Hulsman, Camille Charbonnier, Benjamin Grenier-Boley, Olivier Quenez, Detelina Grozeva, Jeroen G J van Rooij, Rebecca Sims, Shahzad Ahmad, Najaf Amin, Penny Norsworthy, Oriol Dols-Icardo, Holger Hummerich, Amit Kawalia, Philippe Amouyel, Gary W Beecham, Claudine Berr, Josh C Bis, Anne Boland, Paola Bossù, Femke H Bouwman, Jose Bras, Dominique Campion, J Nicholas Cochran, Antonio Daniele, Jean-François Dartigues, Stéphanie Debette, Jean-François Deleuze, Nicola Denning, Anita L Destefano, Lindsay A Farrer, Victoria Fernandez, Nick C Fox, Daniela Galimberti, Emmanuelle Génin, Hans Gille, Yann Le Guen, Rita Guerreiro, Jonathan L Haines, Clive Holmes, M Arfan Ikram, Mohammed Kamran Ikram, Iris E Jansen, Robert Kraaij, Mark Lathrop, Afina W Lemstra, Alberto Lleó, Lauren Luckcuck, Rachel Marshall, Eden R Martin, Carlo Masullo, Richard Mayeux, Patrizia Mecocci, Alun Meggy, Merel O Mol, Kevin Morgan, Richard M Myers, Benedetta Nacmias, Adam C Naj, Valerio Napolioni, Pau Pastor, Margaret A Pericak-Vance, Rachel Raybould, Richard Redon, Marcel Jt Reinders, Anne-Claire Richard, Steffi G Riedel-Heller, Fernando Rivadeneira, Stéphane Rousseau, Natalie S Ryan, Salha Saad, Pascual Sanchez-Juan, Gerard D Schellenberg, Philip Scheltens, Jonathan M Schott, Davide Seripa, Daoud Sie, Erik Sistermans, Sandro Sorbi, Rosalina M L van Spaendonk, Gianfranco Spalletta, Niccoló Tesi, Betty M Tijms, Sven J Van Der Lee, André G Uitterlinden, Pieter Jelle Visser, Michael Wagner, David Wallon, Li-San Wang, Aline Zarea, Jordi Clarimón, John C van Swieten, John Hardy, Michael D Greicius, Alfredo Ramirez, Simon Mead, Jennifer S Yokoyama, Wiesje M van der Flier, Carlos Cruchaga, Cornelia M Van Duijn, Julie Williams, Gaël Nicolas, Céline Bellenguez, Jean-Charles Lamber. Exome sequencing identifies rare damaging variants in the ATB8B4 and ABCA1 genes as novel risk factors for Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109061. |
damaging rare variants in the trem2, sorl1 and abca7 genes have been associated with an increased risk of developing alzheimer's disease (ad) with odds ratios that were not observed since the identification of the main ad genetic risk factor, the apoe-ε4 allele. |
2022-02-03 |
2023-08-13 |
Not clear |
| Daniel Ohiokhai Okhuevbi. ABCA7 gene as a potential therapeutic target in the management of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109147. |
abca7 gene as a potential therapeutic target in the management of alzheimer's disease. |
2022-02-03 |
2023-08-13 |
Not clear |
| Daniel Ohiokhai Okhuevbi. ABCA7 gene as a potential therapeutic target in the management of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109147. |
asides from its function in lipid transport, high levels of abca7 is expressed in the hippocampus and has been identified with alzheimer's disease (ad) risk. |
2022-02-03 |
2023-08-13 |
Not clear |
| Kaitlyn E Stepler, Taneisha R Gillyard, Calla B Reed, Tyra M Avery, Jamaine S Davis, Renã A S Robinso. ABCA7, a Genetic Risk Factor Associated with Alzheimer's Disease Risk in African Americans. Journal of Alzheimer's disease : JAD. 2022-01-17. PMID:35034901. |
abca7, a genetic risk factor associated with alzheimer's disease risk in african americans. |
2022-01-17 |
2023-08-13 |
Not clear |
| Vigneshwaran Namasivayam, Katja Stefan, Jens Pahnke, Sven Marcel Stefa. Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics. Computational and structural biotechnology journal. vol 19. 2022-01-03. PMID:34976306. |
binding mode analysis of abca7 for the prediction of novel alzheimer's disease therapeutics. |
2022-01-03 |
2023-08-13 |
Not clear |
| Vigneshwaran Namasivayam, Katja Stefan, Jens Pahnke, Sven Marcel Stefa. Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics. Computational and structural biotechnology journal. vol 19. 2022-01-03. PMID:34976306. |
the adenosine-triphosphate-(atp)-binding cassette (abc) transporter abca7 is a genetic risk factor for alzheimer's disease (ad). |
2022-01-03 |
2023-08-13 |
Not clear |
| Liling Dong, Chenhui Mao, Caiyan Liu, Jie Li, Xinying Huang, Jie Wang, Dan Lei, Shanshan Chu, Longze Sha, Qi Xu, Bin Peng, Liying Cui, Jing Ga. Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort. Journal of Alzheimer's disease : JAD. 2021-12-27. PMID:34958020. |
association between common variants of apoe, abca7, a2m, bace1, and cerebrospinal fluid biomarkers in alzheimer's disease: data from the pumch dementia cohort. |
2021-12-27 |
2023-08-13 |
Not clear |
| Liling Dong, Chenhui Mao, Caiyan Liu, Jie Li, Xinying Huang, Jie Wang, Dan Lei, Shanshan Chu, Longze Sha, Qi Xu, Bin Peng, Liying Cui, Jing Ga. Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort. Journal of Alzheimer's disease : JAD. 2021-12-27. PMID:34958020. |
the previous studies have identified several genes in relation to alzheimer's disease (ad), such as abca7, cr1, etc. |
2021-12-27 |
2023-08-13 |
Not clear |
| b' Nicholas N Lyssenko, Domenico Pratic\\xc3\\xb. ABCA7 and the altered lipidostasis hypothesis of Alzheimer\'s disease. Alzheimer\'s & dementia : the journal of the Alzheimer\'s Association. vol 17. issue 2. 2021-11-15. PMID:33336544.' |
abca7 and the altered lipidostasis hypothesis of alzheimer's disease. |
2021-11-15 |
2023-08-13 |
Not clear |
| Liene Bossaerts, Elisabeth Hens, Bernard Hanseeuw, Rik Vandenberghe, Patrick Cras, Peter P De Deyn, Sebastiaan Engelborghs, Christine Van Broeckhove. Premature termination codon mutations in ABCA7 contribute to Alzheimer's disease risk in Belgian patients. Neurobiology of aging. vol 106. 2021-09-14. PMID:34090711. |
premature termination codon mutations in abca7 contribute to alzheimer's disease risk in belgian patients. |
2021-09-14 |
2023-08-13 |
Not clear |
| Liene Bossaerts, Elisabeth Hens, Bernard Hanseeuw, Rik Vandenberghe, Patrick Cras, Peter P De Deyn, Sebastiaan Engelborghs, Christine Van Broeckhove. Premature termination codon mutations in ABCA7 contribute to Alzheimer's disease risk in Belgian patients. Neurobiology of aging. vol 106. 2021-09-14. PMID:34090711. |
the atp-binding cassette subfamily a member 7 gene (abca7) was identified as a risk gene for alzheimer's disease (ad) in genome-wide association studies of large cohorts of late-onset ad (load) patients. |
2021-09-14 |
2023-08-13 |
Not clear |
| Brian W Kunkle, Michael Schmidt, Hans-Ulrich Klein, Adam C Naj, Kara L Hamilton-Nelson, Eric B Larson, Denis A Evans, Phil L De Jager, Paul K Crane, Joe D Buxbaum, Nilufer Ertekin-Taner, Lisa L Barnes, M Daniele Fallin, Jennifer J Manly, Rodney C P Go, Thomas O Obisesan, M Ilyas Kamboh, David A Bennett, Kathleen S Hall, Alison M Goate, Tatiana M Foroud, Eden R Martin, Li-Sao Wang, Goldie S Byrd, Lindsay A Farrer, Jonathan L Haines, Gerard D Schellenberg, Richard Mayeux, Margaret A Pericak-Vance, Christiane Reitz, Neill R Graff-Radford, Izri Martinez, Temitope Ayodele, Mark W Logue, Laura B Cantwell, Melissa Jean-Francois, Amanda B Kuzma, L D Adams, Jeffery M Vance, Michael L Cuccaro, Jaeyoon Chung, Jesse Mez, Kathryn L Lunetta, Gyungah R Jun, Oscar L Lopez, Hugh C Hendrie, Eric M Reiman, Neil W Kowall, James B Leverenz, Scott A Small, Allan I Levey, Todd E Golde, Andrew J Saykin, Takiyah D Starks, Marilyn S Albert, Bradley T Hyman, Ronald C Petersen, Mary Sano, Thomas Wisniewski, Robert Vassar, Jeffrey A Kaye, Victor W Henderson, Charles DeCarli, Frank M LaFerla, James B Brewer, Bruce L Miller, Russell H Swerdlow, Linda J Van Eldik, Henry L Paulson, John Q Trojanowski, Helena C Chui, Roger N Rosenberg, Suzanne Craft, Thomas J Grabowski, Sanjay Asthana, John C Morris, Stephen M Strittmatter, Walter A Kukul. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA neurology. vol 78. issue 1. 2021-06-25. PMID:33074286. |
in the largest association analyses of alzheimer disease in african american individuals, abca7, trem2, and an intergenic locus at 5q35 were previously implicated. |
2021-06-25 |
2023-08-13 |
Not clear |
| Guiyou Liu, Haihua Zhang, Bian Liu, Tao Wang, Zhifa Han, Xunming J. rs4147929 variant minor allele increases ABCA7 gene expression and ABCA7 shows increased gene expression in Alzheimer's disease patients compared with controls. Acta neuropathologica. vol 139. issue 5. 2021-06-08. PMID:32112171. |
rs4147929 variant minor allele increases abca7 gene expression and abca7 shows increased gene expression in alzheimer's disease patients compared with controls. |
2021-06-08 |
2023-08-13 |
Not clear |
| Shiraz Dib, Jens Pahnke, Fabien Gossele. Role of ABCA7 in Human Health and in Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 9. 2021-06-08. PMID:33925691. |
role of abca7 in human health and in alzheimer's disease. |
2021-06-08 |
2023-08-13 |
human |
| Shiraz Dib, Jens Pahnke, Fabien Gossele. Role of ABCA7 in Human Health and in Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 9. 2021-06-08. PMID:33925691. |
several studies, including genome wide association studies (gwas), have strongly suggested a central role for the atp-binding cassette transporter subfamily a member 7 (abca7) in alzheimer's disease (ad). |
2021-06-08 |
2023-08-13 |
human |
| Jianxiong Xi, Ding Ding, Qianhua Zhao, Xiaoniu Liang, Li Zheng, Qihao Guo, Zhen Hong, Hua Fu, Jianfeng Xu, Qianyi Xia. Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer's Disease: The Shanghai Aging Study. Current Alzheimer research. vol 17. issue 2. 2021-06-02. PMID:32183673. |
joint effect of abca7 rs4147929 and body mass index on progression from mild cognitive impairment to alzheimer's disease: the shanghai aging study. |
2021-06-02 |
2023-08-13 |
Not clear |
| Mehak Agarwal, Safeera Kha. Plasma Lipids as Biomarkers for Alzheimer's Disease: A Systematic Review. Cureus. vol 12. issue 12. 2021-01-19. PMID:33457117. |
genetic mutations in apolipoprotein e (apoe), apolipoprotein b (apob), apolipoprotein a (apoa), atp binding cassette transporter 1 (abca1), atp binding cassette transporter 7 (abca7), amyloid precursor protein (app), cytochrome p450 family 46 subfamilies a member 1 (cyp46a1), presenilin 1 (psen1), presenilin 2 (psen2) are also associated with increased risk of alzheimer's disease. |
2021-01-19 |
2023-08-13 |
Not clear |
| Sumiko Abe-Dohmae, Shinji Yokoyam. ABCA7 links sterol metabolism to the host defense system: Molecular background for potential management measure of Alzheimer's disease. Gene. vol 768. 2021-01-18. PMID:33221536. |
abca7 links sterol metabolism to the host defense system: molecular background for potential management measure of alzheimer's disease. |
2021-01-18 |
2023-08-13 |
Not clear |
| Sumiko Abe-Dohmae, Shinji Yokoyam. ABCA7 links sterol metabolism to the host defense system: Molecular background for potential management measure of Alzheimer's disease. Gene. vol 768. 2021-01-18. PMID:33221536. |
the interest is being build up in abca7 as its genomic diversity has been found related to a risk for late-onset alzheimer's diseases. |
2021-01-18 |
2023-08-13 |
Not clear |