| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongyun Li, Tim Karl, Brett Garne. Abca7 deletion does not affect adult neurogenesis in the mouse. Bioscience reports. vol 36. issue 2. 2016-12-13. PMID:26792809. |
recent genome-wide association studies (gwas) have identified abca7 single nucleotide polymorphisms (snps) that increase alzheimer's disease (ad) risk, however, the mechanisms by which abca7 may control ad risk remain to be fully elucidated. |
2016-12-13 |
2023-08-13 |
mouse |
| Hongyun Li, Tim Karl, Brett Garne. Understanding the function of ABCA7 in Alzheimer's disease. Biochemical Society transactions. vol 43. issue 5. 2016-08-31. PMID:26517904. |
understanding the function of abca7 in alzheimer's disease. |
2016-08-31 |
2023-08-13 |
mouse |
| Hongyun Li, Tim Karl, Brett Garne. Understanding the function of ABCA7 in Alzheimer's disease. Biochemical Society transactions. vol 43. issue 5. 2016-08-31. PMID:26517904. |
recent genome-wide association studies (gwas) identify abca7 single nt polymorphisms (snps) that increase alzheimer's disease (ad) risk. |
2016-08-31 |
2023-08-13 |
mouse |
| Nobutaka Sakae, Chia-Chen Liu, Mitsuru Shinohara, Jessica Frisch-Daiello, Li Ma, Yu Yamazaki, Masaya Tachibana, Linda Younkin, Aishe Kurti, Minerva M Carrasquillo, Fanggeng Zou, Daniel Sevlever, Gina Bisceglio, Ming Gan, Romain Fol, Patrick Knight, Miao Wang, Xianlin Han, John D Fryer, Michael L Fitzgerald, Yasumasa Ohyagi, Steven G Younkin, Guojun Bu, Takahisa Kanekiy. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 13. 2016-08-08. PMID:27030769. |
abca7 deficiency accelerates amyloid-β generation and alzheimer's neuronal pathology. |
2016-08-08 |
2023-08-13 |
mouse |
| Holly N Cukier, Brian W Kunkle, Badri N Vardarajan, Sophie Rolati, Kara L Hamilton-Nelson, Martin A Kohli, Patrice L Whitehead, Beth A Dombroski, Derek Van Booven, Rosalyn Lang, Derek M Dykxhoorn, Lindsay A Farrer, Michael L Cuccaro, Jeffery M Vance, John R Gilbert, Gary W Beecham, Eden R Martin, Regina M Carney, Richard Mayeux, Gerard D Schellenberg, Goldie S Byrd, Jonathan L Haines, Margaret A Pericak-Vanc. ABCA7 frameshift deletion associated with Alzheimer disease in African Americans. Neurology. Genetics. vol 2. issue 3. 2016-05-27. PMID:27231719. |
abca7 frameshift deletion associated with alzheimer disease in african americans. |
2016-05-27 |
2023-08-13 |
Not clear |
| Holly N Cukier, Brian W Kunkle, Badri N Vardarajan, Sophie Rolati, Kara L Hamilton-Nelson, Martin A Kohli, Patrice L Whitehead, Beth A Dombroski, Derek Van Booven, Rosalyn Lang, Derek M Dykxhoorn, Lindsay A Farrer, Michael L Cuccaro, Jeffery M Vance, John R Gilbert, Gary W Beecham, Eden R Martin, Regina M Carney, Richard Mayeux, Gerard D Schellenberg, Goldie S Byrd, Jonathan L Haines, Margaret A Pericak-Vanc. ABCA7 frameshift deletion associated with Alzheimer disease in African Americans. Neurology. Genetics. vol 2. issue 3. 2016-05-27. PMID:27231719. |
to identify a causative variant(s) that may contribute to alzheimer disease (ad) in african americans (aa) in the atp-binding cassette, subfamily a (abc1), member 7 (abca7) gene, a known risk factor for late-onset ad. |
2016-05-27 |
2023-08-13 |
Not clear |
| Jorge L Del-Aguila, Maria Victoria Fernández, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, Carlos Cruchag. Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European-Americans. Alzheimer's research & therapy. vol 7. issue 1. 2016-05-03. PMID:26654793. |
role of abca7 loss-of-function variant in alzheimer's disease: a replication study in european-americans. |
2016-05-03 |
2023-08-13 |
Not clear |
| Jorge L Del-Aguila, Maria Victoria Fernández, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, Carlos Cruchag. Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European-Americans. Alzheimer's research & therapy. vol 7. issue 1. 2016-05-03. PMID:26654793. |
a recent study found a significant increase of abca7 loss-of-function variants in alzheimer's disease (ad) cases compared to controls. |
2016-05-03 |
2023-08-13 |
Not clear |
| Karen Nuytemans, Lizmarie Maldonado, Aleena Ali, Krista John-Williams, Gary W Beecham, Eden Martin, William K Scott, Jeffery M Vanc. Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants. Neurology. Genetics. vol 2. issue 1. 2016-04-12. PMID:27066581. |
overlap between parkinson disease and alzheimer disease in abca7 functional variants. |
2016-04-12 |
2023-08-13 |
Not clear |
| Karen Nuytemans, Lizmarie Maldonado, Aleena Ali, Krista John-Williams, Gary W Beecham, Eden Martin, William K Scott, Jeffery M Vanc. Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants. Neurology. Genetics. vol 2. issue 1. 2016-04-12. PMID:27066581. |
given their reported function in phagocytosis and clearance of protein aggregates in alzheimer disease (ad), we hypothesized that variants in atp-binding cassette transporter a7 (abca7) might be involved in parkinson disease (pd). |
2016-04-12 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Jin-Tai Yu, Meng-Shan Tan, Lan Ta. ABCA7 in Alzheimer's Disease. Molecular neurobiology. vol 51. issue 3. 2016-02-12. PMID:24878767. |
abca7 in alzheimer's disease. |
2016-02-12 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Jin-Tai Yu, Meng-Shan Tan, Lan Ta. ABCA7 in Alzheimer's Disease. Molecular neurobiology. vol 51. issue 3. 2016-02-12. PMID:24878767. |
atp-binding cassette a7 (abca7) gene has recently been identified as a strong genetic locus associated with late-onset alzheimer's disease (load) through genome-wide association studies (gwass). |
2016-02-12 |
2023-08-13 |
Not clear |
| Qing-Fei Zhao, Jin-Tai Yu, Meng-Shan Tan, Lan Ta. ABCA7 in Alzheimer's Disease. Molecular neurobiology. vol 51. issue 3. 2016-02-12. PMID:24878767. |
the levels of abca7 have been detected to be increased in the alzheimer's disease (ad) brain, which positively correlated with amyloid plaque burden and disease severity. |
2016-02-12 |
2023-08-13 |
Not clear |
| Kanayo Satoh, Sumiko Abe-Dohmae, Shinji Yokoyama, Peter St George-Hyslop, Paul E Frase. ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing. The Journal of biological chemistry. vol 290. issue 40. 2016-01-06. PMID:26260791. |
atp-binding cassette transporter a7 (abca7) loss of function alters alzheimer amyloid processing. |
2016-01-06 |
2023-08-13 |
mouse |
| Kanayo Satoh, Sumiko Abe-Dohmae, Shinji Yokoyama, Peter St George-Hyslop, Paul E Frase. ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing. The Journal of biological chemistry. vol 290. issue 40. 2016-01-06. PMID:26260791. |
the atp-binding cassette transporter a7 (abca7) has been identified as a susceptibility factor of late onset alzheimer disease in genome-wide association studies. |
2016-01-06 |
2023-08-13 |
mouse |
| Kanayo Satoh, Sumiko Abe-Dohmae, Shinji Yokoyama, Peter St George-Hyslop, Paul E Frase. ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing. The Journal of biological chemistry. vol 290. issue 40. 2016-01-06. PMID:26260791. |
several potential loss-of-function abca7 mutations and deletions linked to alzheimer disease that in some instances have a greater impact than apoe allelic variants have recently been identified. |
2016-01-06 |
2023-08-13 |
mouse |
| Kanayo Satoh, Sumiko Abe-Dohmae, Shinji Yokoyama, Peter St George-Hyslop, Paul E Frase. ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing. The Journal of biological chemistry. vol 290. issue 40. 2016-01-06. PMID:26260791. |
a reduction in abca7 expression or loss of function would be predicted to increase amyloid production and that may be a contributing factor in the associated alzheimer disease susceptibility. |
2016-01-06 |
2023-08-13 |
mouse |
| Elise Cuyvers, Arne De Roeck, Tobi Van den Bossche, Caroline Van Cauwenberghe, Karolien Bettens, Steven Vermeulen, Maria Mattheijssens, Karin Peeters, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Rik Vandenberghe, Peter P De Deyn, Christine Van Broeckhoven, Kristel Sleeger. Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study. The Lancet. Neurology. vol 14. issue 8. 2015-10-15. PMID:26141617. |
mutations in abca7 in a belgian cohort of alzheimer's disease patients: a targeted resequencing study. |
2015-10-15 |
2023-08-13 |
Not clear |
| Elise Cuyvers, Arne De Roeck, Tobi Van den Bossche, Caroline Van Cauwenberghe, Karolien Bettens, Steven Vermeulen, Maria Mattheijssens, Karin Peeters, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Rik Vandenberghe, Peter P De Deyn, Christine Van Broeckhoven, Kristel Sleeger. Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study. The Lancet. Neurology. vol 14. issue 8. 2015-10-15. PMID:26141617. |
abca7 was identified as a risk gene for alzheimer's disease in genome-wide association studies (gwas). |
2015-10-15 |
2023-08-13 |
Not clear |
| Elise Cuyvers, Arne De Roeck, Tobi Van den Bossche, Caroline Van Cauwenberghe, Karolien Bettens, Steven Vermeulen, Maria Mattheijssens, Karin Peeters, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Rik Vandenberghe, Peter P De Deyn, Christine Van Broeckhoven, Kristel Sleeger. Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study. The Lancet. Neurology. vol 14. issue 8. 2015-10-15. PMID:26141617. |
using targeted resequencing, we investigated abca7 in this cohort with the aim to directly detect rare and common variations in this gene associated with alzheimer's disease pathogenesis. |
2015-10-15 |
2023-08-13 |
Not clear |