| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahdi Ghani, Anthony E Lang, Lorne Zinman, Benedetta Nacmias, Sandro Sorbi, Valentina Bessi, Andrea Tedde, Maria Carmela Tartaglia, Ezequiel I Surace, Christine Sato, Danielle Moreno, Zhengrui Xi, Rachel Hung, Mike A Nalls, Andrew Singleton, Peter St George-Hyslop, Ekaterina Rogaev. Mutation analysis of patients with neurodegenerative disorders using NeuroX array. Neurobiology of aging. vol 36. issue 1. 2015-09-21. PMID:25174650. |
in total, we identified 78 potentially damaging rare variants (frequency <1%), including abca7 p.l400v in a family with alzheimer's disease and lrrk2 p.r1514q in 6 of 98 patients with parkinson's disease (6.1%). |
2015-09-21 |
2023-08-13 |
Not clear |
| Guiyou Liu, Fujun Li, Shuyan Zhang, Yongshuai Jiang, Guoda Ma, Hong Shang, Jiafeng Liu, Rennan Feng, Liangcai Zhang, Mingzhi Liao, Bin Zhao, Keshen L. Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility. Molecular neurobiology. vol 50. issue 3. 2015-07-08. PMID:24643655. |
analyzing large-scale samples confirms the association between the abca7 rs3764650 polymorphism and alzheimer's disease susceptibility. |
2015-07-08 |
2023-08-12 |
Not clear |
| Guiyou Liu, Fujun Li, Shuyan Zhang, Yongshuai Jiang, Guoda Ma, Hong Shang, Jiafeng Liu, Rennan Feng, Liangcai Zhang, Mingzhi Liao, Bin Zhao, Keshen L. Analyzing large-scale samples confirms the association between the ABCA7 rs3764650 polymorphism and Alzheimer's disease susceptibility. Molecular neurobiology. vol 50. issue 3. 2015-07-08. PMID:24643655. |
large-scale genome-wide association studies (gwas) have revealed that the abca7 rs3764650 polymorphism (or its proxies, namely rs115550680, rs3752246, and rs4147929) is associated with alzheimer's disease (ad) susceptibility in individuals of caucasian ancestry. |
2015-07-08 |
2023-08-12 |
Not clear |
| Stacy Steinberg, Hreinn Stefansson, Thorlakur Jonsson, Hrefna Johannsdottir, Andres Ingason, Hannes Helgason, Patrick Sulem, Olafur Th Magnusson, Sigurjon A Gudjonsson, Unnur Unnsteinsdottir, Augustine Kong, Seppo Helisalmi, Hilkka Soininen, James J Lah, Dag Aarsland, Tormod Fladby, Ingun D Ulstein, Srdjan Djurovic, Sigrid B Sando, Linda R White, Gun-Peggy Knudsen, Lars T Westlye, Geir Selbæk, Ina Giegling, Harald Hampel, Mikko Hiltunen, Allan I Levey, Ole A Andreassen, Dan Rujescu, Palmi V Jonsson, Sigurbjorn Bjornsson, Jon Snaedal, Kari Stefansso. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nature genetics. vol 47. issue 5. 2015-07-06. PMID:25807283. |
loss-of-function variants in abca7 confer risk of alzheimer's disease. |
2015-07-06 |
2023-08-13 |
Not clear |
| Stacy Steinberg, Hreinn Stefansson, Thorlakur Jonsson, Hrefna Johannsdottir, Andres Ingason, Hannes Helgason, Patrick Sulem, Olafur Th Magnusson, Sigurjon A Gudjonsson, Unnur Unnsteinsdottir, Augustine Kong, Seppo Helisalmi, Hilkka Soininen, James J Lah, Dag Aarsland, Tormod Fladby, Ingun D Ulstein, Srdjan Djurovic, Sigrid B Sando, Linda R White, Gun-Peggy Knudsen, Lars T Westlye, Geir Selbæk, Ina Giegling, Harald Hampel, Mikko Hiltunen, Allan I Levey, Ole A Andreassen, Dan Rujescu, Palmi V Jonsson, Sigurbjorn Bjornsson, Jon Snaedal, Kari Stefansso. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nature genetics. vol 47. issue 5. 2015-07-06. PMID:25807283. |
we found that loss-of-function variants in abca7 confer risk of alzheimer's disease in icelanders (odds ratio (or) = 2.12, p = 2.2 × 10(-13)) and discovered that the association replicated in study groups from europe and the united states (combined or = 2.03, p = 6.8 × 10(-15)). |
2015-07-06 |
2023-08-13 |
Not clear |
| Lei Yu, Lori B Chibnik, Gyan P Srivastava, Nathalie Pochet, Jingyun Yang, Jishu Xu, James Kozubek, Nikolaus Obholzer, Sue E Leurgans, Julie A Schneider, Alexander Meissner, Philip L De Jager, David A Bennet. Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease. JAMA neurology. vol 72. issue 1. 2015-03-18. PMID:25365775. |
association of brain dna methylation in sorl1, abca7, hla-drb5, slc24a4, and bin1 with pathological diagnosis of alzheimer disease. |
2015-03-18 |
2023-08-13 |
Not clear |
| Yi-Chu Liao, Wei-Ju Lee, Jeng-Ping Hwang, Yen-Feng Wang, Chia-Fen Tsai, Pei-Ning Wang, Shuu-Jiun Wang, Jong-Ling Fu. ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan. Neurobiology of aging. vol 35. issue 10. 2015-02-09. PMID:24908168. |
abca7 gene and the risk of alzheimer's disease in han chinese in taiwan. |
2015-02-09 |
2023-08-13 |
Not clear |
| Yi-Chu Liao, Wei-Ju Lee, Jeng-Ping Hwang, Yen-Feng Wang, Chia-Fen Tsai, Pei-Ning Wang, Shuu-Jiun Wang, Jong-Ling Fu. ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan. Neurobiology of aging. vol 35. issue 10. 2015-02-09. PMID:24908168. |
the atp-binding cassette, subfamily a, member 7 gene (abca7) was recently identified as a susceptible gene of alzheimer's disease (ad) in the caucasian population and african americans. |
2015-02-09 |
2023-08-13 |
Not clear |
| Li-Hua Liu, Jun Xu, Yu-Lei Deng, Hui-Dong Tang, Ying Wang, Ru-Jing Ren, Wei Xu, Jian-Fang Ma, Gang Wang, Sheng-Di Che. A complex association of ABCA7 genotypes with sporadic Alzheimer disease in Chinese Han population. Alzheimer disease and associated disorders. vol 28. issue 2. 2015-01-02. PMID:24113560. |
a complex association of abca7 genotypes with sporadic alzheimer disease in chinese han population. |
2015-01-02 |
2023-08-12 |
Not clear |
| Li-Hua Liu, Jun Xu, Yu-Lei Deng, Hui-Dong Tang, Ying Wang, Ru-Jing Ren, Wei Xu, Jian-Fang Ma, Gang Wang, Sheng-Di Che. A complex association of ABCA7 genotypes with sporadic Alzheimer disease in Chinese Han population. Alzheimer disease and associated disorders. vol 28. issue 2. 2015-01-02. PMID:24113560. |
recently, a large genome-wide association study has revealed that polymorphism of alleles and genotypes in rs3,764,650 within abca7 gene is associated with alzheimer disease in whites. |
2015-01-02 |
2023-08-12 |
Not clear |
| Sun Ju Chung, Mi-Jung Kim, Young Jin Kim, Juyeon Kim, Sooyeoun You, Eun Hye Jang, Seong Yoon Kim, Jae-Hong Le. CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease. Journal of the neurological sciences. vol 339. issue 1-2. 2014-12-08. PMID:24530172. |
cr1, abca7, and apoe genes affect the features of cognitive impairment in alzheimer's disease. |
2014-12-08 |
2023-08-12 |
Not clear |
| Mark T W Ebbert, Perry G Ridge, Andrew R Wilson, Aaron R Sharp, Matthew Bailey, Maria C Norton, JoAnn T Tschanz, Ronald G Munger, Christopher D Corcoran, John S K Kauw. Population-based analysis of Alzheimer's disease risk alleles implicates genetic interactions. Biological psychiatry. vol 75. issue 9. 2014-12-04. PMID:23954108. |
reported odds ratios and population attributable fractions (paf) for late-onset alzheimer's disease (load) risk loci (bin1, abca7, cr1, ms4a4e, cd2ap, picalm, ms4a6a, cd33, and clu) come from clinically ascertained samples. |
2014-12-04 |
2023-08-12 |
Not clear |
| Ping Yang, Yi-Min Sun, Zhi-Jun Liu, Qing-Qing Tao, Hong-Lei Li, Shen-Ji Lu, Zhi-Ying W. Association study of ABCA7 and NPC1 polymorphisms with Alzheimer's disease in Chinese Han ethnic population. Psychiatric genetics. vol 23. issue 6. 2014-06-12. PMID:24064683. |
association study of abca7 and npc1 polymorphisms with alzheimer's disease in chinese han ethnic population. |
2014-06-12 |
2023-08-12 |
Not clear |
| Lan Tan, Jin-Tai Yu, Wei Zhang, Zhong-Chen Wu, Qun Zhang, Qiu-Yan Liu, Wei Wang, Hui-Fu Wang, Xiao-Ying Ma, Wei-Zhen Cu. Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 5. 2014-03-25. PMID:23232270. |
five genomewide association studies (gwas) in white populations have recently identified and confirmed 9 novel alzheimer's disease (ad) susceptibility loci (clu, cr1, picalm, bin1, abca7, ms4a gene cluster, cd2ap, cd33, and epha1). |
2014-03-25 |
2023-08-12 |
Not clear |
| Jared B Vasquez, David W Fardo, Steven Estu. ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status. Neuroscience letters. vol 556. 2014-02-10. PMID:24141082. |
abca7 expression is associated with alzheimer's disease polymorphism and disease status. |
2014-02-10 |
2023-08-12 |
human |
| Patrick Holton, Mina Ryten, Michael Nalls, Daniah Trabzuni, Michael E Weale, Dena Hernandez, Helen Crehan, J Raphael Gibbs, Richard Mayeux, Jonathan L Haines, Lindsay A Farrer, Margaret A Pericak-Vance, Gerard D Schellenberg, Manuel Ramirez-Restrepo, Anzhelika Engel, Amanda J Myers, Jason J Corneveaux, Matthew J Huentelman, Allissa Dillman, Mark R Cookson, Eric M Reiman, Andrew Singleton, John Hardy, Rita Guerreir. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Annals of human genetics. vol 77. issue 2. 2013-05-23. PMID:23360175. |
recent genome wide association studies have identified clu, cr1, abca7 bin1, picalm and ms4a6a/ms4a6e in addition to the long established apoe, as loci for alzheimer's disease. |
2013-05-23 |
2023-08-12 |
Not clear |
| Woojin S Kim, Hongyun Li, Kalani Ruberu, Sharon Chan, David A Elliott, Jac Kee Low, David Cheng, Tim Karl, Brett Garne. Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 10. 2013-04-26. PMID:23467355. |
deletion of abca7 increases cerebral amyloid-β accumulation in the j20 mouse model of alzheimer's disease. |
2013-04-26 |
2023-08-12 |
mouse |
| Woojin S Kim, Hongyun Li, Kalani Ruberu, Sharon Chan, David A Elliott, Jac Kee Low, David Cheng, Tim Karl, Brett Garne. Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 10. 2013-04-26. PMID:23467355. |
abca7 promotes efflux of lipids from cells to apolipoproteins and can also regulate phagocytosis and modulate processing of amyloid precursor protein (app) to generate the alzheimer's disease (ad) amyloid-β (aβ) peptide. |
2013-04-26 |
2023-08-12 |
mouse |
| Christiane Reitz, Gyungah Jun, Adam Naj, Ruchita Rajbhandary, Badri Narayan Vardarajan, Li-San Wang, Otto Valladares, Chiao-Feng Lin, Eric B Larson, Neill R Graff-Radford, Denis Evans, Philip L De Jager, Paul K Crane, Joseph D Buxbaum, Jill R Murrell, Towfique Raj, Nilufer Ertekin-Taner, Mark Logue, Clinton T Baldwin, Robert C Green, Lisa L Barnes, Laura B Cantwell, M Daniele Fallin, Rodney C P Go, Patrick Griffith, Thomas O Obisesan, Jennifer J Manly, Kathryn L Lunetta, M Ilyas Kamboh, Oscar L Lopez, David A Bennett, Hugh Hendrie, Kathleen S Hall, Alison M Goate, Goldie S Byrd, Walter A Kukull, Tatiana M Foroud, Jonathan L Haines, Lindsay A Farrer, Margaret A Pericak-Vance, Gerard D Schellenberg, Richard Mayeu. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. vol 309. issue 14. 2013-04-11. PMID:23571587. |
variants in the atp-binding cassette transporter (abca7), apolipoprotein e ϵ4,and the risk of late-onset alzheimer disease in african americans. |
2013-04-11 |
2023-08-12 |
Not clear |
| Warren Logge, David Cheng, Rose Chesworth, Surabhi Bhatia, Brett Garner, Woojin Scott Kim, Tim Kar. Role of Abca7 in mouse behaviours relevant to neurodegenerative diseases. PloS one. vol 7. issue 9. 2013-03-05. PMID:23029339. |
recent studies suggest that the abc transporter abca7 may play a role in the development of brain disorders such as schizophrenia and alzheimer's disease. |
2013-03-05 |
2023-08-12 |
mouse |