| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Emoto, E Ohmura, O Isozaki, T Tsushima, K Shizume, H Demur. Phorbol ester, not growth hormone releasing factor, consistently stimulates growth hormone release from somatotroph adenomas in culture. Clinical endocrinology. vol 34. issue 5. 1991-08-08. PMID:2060147. |
however, it is not determined whether the protein kinase c is involved in the in-vivo production of gh in patients with acromegaly. |
1991-08-08 |
2023-08-11 |
human |
| H Uhlig, W Saeger, S Fehr, D K Lüdeck. Detection of growth hormone, prolactin and human beta-chorionic gonadotropin messenger RNA in growth-hormone-secreting pituitary adenomas by in situ hybridization. Virchows Archiv. A, Pathological anatomy and histopathology. vol 418. issue 6. 1991-07-26. PMID:2058088. |
in a series of 39 adenomas from patients with the clinical hyperfunction syndrome of acromegaly and in one from a case of prolactinoma we studied the mrna expression of growth hormone (gh), prolactin (prl) and beta-human chorionic gonadotropin (hcg) by using this technique of in situ hybridization (ish). |
1991-07-26 |
2023-08-11 |
human |
| H O Andersen, P E Jørgensen, L Bardram, L Hilste. Screening for multiple endocrine neoplasia type 1 in patients with recognized pituitary adenoma. Clinical endocrinology. vol 33. issue 6. 1991-07-18. PMID:1982864. |
the 79 patients included 21 patients with acromegaly, nine with cushing's disease, 18 with prolactinomas, three with mixed pituitary adenomas (gh and prl), and 28 patients with no detectable hypersecretion of hormones. |
1991-07-18 |
2023-08-11 |
Not clear |
| T Tokuyama, M Yoshinari, K Okamura, H Ikenoue, K Sato, T Kuroda, M Fujishim. [The relationship between TSH response to TRH and GH response to dopaminergic agents in patients with acromegaly]. Nihon Naibunpi Gakkai zasshi. vol 67. issue 2. 1991-07-10. PMID:1674920. |
[the relationship between tsh response to trh and gh response to dopaminergic agents in patients with acromegaly]. |
1991-07-10 |
2023-08-11 |
Not clear |
| T Tokuyama, M Yoshinari, K Okamura, H Ikenoue, K Sato, T Kuroda, M Fujishim. [The relationship between TSH response to TRH and GH response to dopaminergic agents in patients with acromegaly]. Nihon Naibunpi Gakkai zasshi. vol 67. issue 2. 1991-07-10. PMID:1674920. |
the role of dopaminergic agents (da) in the regulation of growth hormone (gh) secretion was investigated in patients with untreated acromegaly. |
1991-07-10 |
2023-08-11 |
Not clear |
| R Candrin. Paradoxic elevation in serum GH by hypothalamic releasing hormones predicts GH response to acute SMS 201-995 administration. Recenti progressi in medicina. vol 82. issue 1. 1991-06-10. PMID:1902962. |
in order to find a parameter predictive of the effectiveness of the drug, we studied in twelve patients with active acromegaly the relationship between paradoxical gh response to gonadotropin- and thyrotropin-releasing hormone (gnrh and trh) and gh inhibition after a single standard dose (100 micrograms) of sms 201-995. |
1991-06-10 |
2023-08-11 |
Not clear |
| R Candrin. Paradoxic elevation in serum GH by hypothalamic releasing hormones predicts GH response to acute SMS 201-995 administration. Recenti progressi in medicina. vol 82. issue 1. 1991-06-10. PMID:1902962. |
sms 201-995 appears an effective means for suppressing the elevated gh levels in active acromegaly. |
1991-06-10 |
2023-08-11 |
Not clear |
| J A McKnight, D R McCance, B Sheridan, E McIlrath, D R Hadden, L Kennedy, A B Atkinso. A long-term dose-response study of somatostatin analogue (SMS 201-995, octreotide) in resistant acromegaly. Clinical endocrinology. vol 34. issue 2. 1991-06-06. PMID:1902408. |
in conclusion, octreotide lowered gh levels in acromegaly over a 1-year period. |
1991-06-06 |
2023-08-11 |
human |
| H Watanobe, S Sasaki, K Sone, K Takeb. Paradoxical response of growth hormone to peptide histidine methionine in acromegaly: comparison with the effects of thyrotropin-releasing hormone and vasoactive intestinal peptide. The Journal of clinical endocrinology and metabolism. vol 72. issue 5. 1991-06-06. PMID:1902488. |
we examined whether peptide histidine methionine (phm) induces a paradoxical rise in plasma gh in patients with acromegaly. |
1991-06-06 |
2023-08-11 |
Not clear |
| H Watanobe, S Sasaki, K Sone, K Takeb. Paradoxical response of growth hormone to peptide histidine methionine in acromegaly: comparison with the effects of thyrotropin-releasing hormone and vasoactive intestinal peptide. The Journal of clinical endocrinology and metabolism. vol 72. issue 5. 1991-06-06. PMID:1902488. |
phm (100 micrograms) was given as an iv bolus to eight patients with active acromegaly, and plasma gh levels were measured before and at intervals up to 120 min after the injection. |
1991-06-06 |
2023-08-11 |
Not clear |
| N Bazzoni, B Ambrosi, M Arosio, M Barbareschi, M Losa, G Fagli. Acromegaly and thymic hyperplasia: a case report. Journal of endocrinological investigation. vol 13. issue 11. 1991-06-06. PMID:2090673. |
these data ruled out a ghrh and/or gh ectopic production, confirming the primitive pituitary origin of acromegaly in this patient. |
1991-06-06 |
2023-08-11 |
Not clear |
| N Hattori, A Shimatsu, T Tanoh, H Koshiyama, Y Kato, H Imur. Evaluation of activity in postoperative acromegalics--plasma growth hormone levels during oral glucose tolerance test, daytime blood sampling and urinary GH excretion. Endocrinologia japonica. vol 37. issue 5. 1991-05-17. PMID:2128272. |
plasma growth hormone (gh) levels during oral glucose tolerance test (ogtt) and during the daytime (0900-1700 h) and urinary gh excretion were determined in 6 normal subjects and 10 patients with postoperative acromegaly by means of a highly sensitive enzyme immunoassay (eia). |
1991-05-17 |
2023-08-11 |
human |
| N Hattori, A Shimatsu, T Tanoh, H Koshiyama, Y Kato, H Imur. Evaluation of activity in postoperative acromegalics--plasma growth hormone levels during oral glucose tolerance test, daytime blood sampling and urinary GH excretion. Endocrinologia japonica. vol 37. issue 5. 1991-05-17. PMID:2128272. |
determination of plasma gh levels during ogtt and urinary gh excretion by the highly sensitive enzyme immunoassay is useful in evaluating the activity of postoperative acromegaly. |
1991-05-17 |
2023-08-11 |
human |
| Y F Sh. [Studies on the abnormal response of pituitary somatotropin to dopaminergic drugs in patients with acromegaly]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 12. issue 3. 1991-05-01. PMID:2150352. |
simultaneous administration of l-dopa and carbidopa (a drug that inhibits the conversion of l-dopa to dopamine in peripheral tissue) showed no suppressive or stimulatory effect on the secretion of gh in acromegaly. |
1991-05-01 |
2023-08-11 |
Not clear |
| Y F Sh. [Studies on the abnormal response of pituitary somatotropin to dopaminergic drugs in patients with acromegaly]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 12. issue 3. 1991-05-01. PMID:2150352. |
this result indicates that an abnormality in the gh secreting cell may be the cause of the different responses of gh to dopaminergic drugs in acromegaly. |
1991-05-01 |
2023-08-11 |
Not clear |
| S W Kim, S Y Kim, I M Yang, J W Kim, Y S Kim, K W Kim, Y K Cho. GH secretory dynamics and responsiveness to SMS 201-995 treatment in acromegaly. The Korean journal of internal medicine. vol 3. issue 2. 1991-03-15. PMID:3155299. |
gh secretory dynamics and responsiveness to sms 201-995 treatment in acromegaly. |
1991-03-15 |
2023-08-11 |
Not clear |
| H Asada, M Otani, S Furuhata, H Inoue, S Toya, Y Ogaw. Mixed pituitary adenoma and gangliocytoma associated with acromegaly--case report. Neurologia medico-chirurgica. vol 30. issue 8. 1991-03-07. PMID:1703643. |
a 52-year-old female was admitted to our hospital with headache, mild acromegaly, and bitemporal hemianopsia, and endocrinological study found a high serum level of growth hormone (gh). |
1991-03-07 |
2023-08-11 |
Not clear |
| A Liuzzi, D Dallabonzana, G Oppizzi, R Cozzi, P G Chiodin. [Medical treatment of acromegaly with dopaminergic agents]. Minerva endocrinologica. vol 15. issue 1. 1991-02-28. PMID:1980333. |
the medical treatment of acromegaly with dopaminergic drugs has its physiopathological premise in the observation that agents capable of stimulating dopaminergic receptors directly are capable of determining gh secretion inhibition in a large percentage of acromegalic patients. |
1991-02-28 |
2023-08-11 |
Not clear |
| A Liuzzi, D Dallabonzana, G Oppizzi, R Cozzi, P G Chiodin. [Medical treatment of acromegaly with dopaminergic agents]. Minerva endocrinologica. vol 15. issue 1. 1991-02-28. PMID:1980333. |
the antitumoral effect of the dopaminergic frequently encountered in prolactinomas is a rarer event in acromegaly and occurs more readily in patients with mixed secreting gh and prl tumours than in pure gh. |
1991-02-28 |
2023-08-11 |
Not clear |
| R Abs, A Beckers, F L Van de Vyver, A De Schepper, A Stevenaert, G Henne. Acromegaly, multinodular goiter and silent polyostotic fibrous dysplasia. A variant of the McCune-Albright syndrome. Journal of endocrinological investigation. vol 13. issue 8. 1991-02-28. PMID:2273209. |
treatment of the acromegaly with the long-acting somatostatin analogue octreotide resulted in an important inhibition of the gh secretion and in a reduction of the volume of the pituitary adenoma. |
1991-02-28 |
2023-08-11 |
Not clear |