| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Weissberger, K Y Ho, M C Stuar. Quantification of urinary growth hormone (GH) excretion by centrifugal ultrafiltration and radioimmunoassay: appraisal of the relationship between 24 h urinary GH and mean 24 h serum GH levels in normal and abnormal states of GH secretion. Clinical endocrinology. vol 30. issue 6. 1990-01-17. PMID:2591065. |
in contrast, there was no significant correlation between 24 h ugh and mean 24 h serum gh in subjects with active acromegaly, and their 24 h ugh values were not distinguishable from those of the 'non-acromegalic' subjects. |
1990-01-17 |
2023-08-11 |
human |
| A L Barkan, S E Stred, K Reno, M Markovs, N J Hopwood, R P Kelch, I Z Beitin. Increased growth hormone pulse frequency in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 6. 1989-12-29. PMID:2511221. |
to investigate whether gh secretion in acromegaly is subject to regulatory control by the hypothalamic gh-releasing hormone (ghrh) we studied gh secretion in 22 patients with acromegaly. |
1989-12-29 |
2023-08-11 |
human |
| A L Barkan, S E Stred, K Reno, M Markovs, N J Hopwood, R P Kelch, I Z Beitin. Increased growth hormone pulse frequency in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 6. 1989-12-29. PMID:2511221. |
spontaneous gh pulse frequency was greater in patients with acromegaly than in 6 control subjects (8.6 +/- 0.6 vs. 4.3 +/- 1.1 pulses/24 h), as estimated by the 20-min sampling frequency. |
1989-12-29 |
2023-08-11 |
human |
| A L Barkan, S E Stred, K Reno, M Markovs, N J Hopwood, R P Kelch, I Z Beitin. Increased growth hormone pulse frequency in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 6. 1989-12-29. PMID:2511221. |
a similar degree of nocturnal augmentation of gh secretion was observed in both groups, and it persisted during sms 201-995 therapy in patients with acromegaly. |
1989-12-29 |
2023-08-11 |
human |
| A L Barkan, S E Stred, K Reno, M Markovs, N J Hopwood, R P Kelch, I Z Beitin. Increased growth hormone pulse frequency in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 6. 1989-12-29. PMID:2511221. |
these observations suggest that gh secretion in acromegaly remains under stimulatory control by ghrh, which may be released at an abnormally high rate. |
1989-12-29 |
2023-08-11 |
human |
| S Hardouin, M Gourmelen, P Noguiez, D Seurin, M Roghani, Y Le Bouc, G Povoa, T J Merimee, P Hossenlopp, M Binou. Molecular forms of serum insulin-like growth factor (IGF)-binding proteins in man: relationships with growth hormone and IGFs and physiological significance. The Journal of clinical endocrinology and metabolism. vol 69. issue 6. 1989-12-29. PMID:2555386. |
serum 41.5- and 38.5-kd bps have been found to be elevated in acromegaly, where gh hypersecretion causes increased igf-i levels, and diminished in cases of genetic or idiopathic gh deficiency and defects of the gh receptor (laron's syndrome), where both igf-i and igf-ii are decreased, as well as in pygmy adults and children who have isolated igf-i deficiency. |
1989-12-29 |
2023-08-11 |
human |
| K Hanew, A Sugawara, Y Shimizu, S Sato, A Sasaki, S Tazawa, K Ishii, T Saitoh, S Saso, K Yoshinag. The combination therapy with bromocriptine and cyproheptadine in patients with acromegaly. Endocrinologia japonica. vol 36. issue 3. 1989-12-22. PMID:2510991. |
the therapeutic efficacy of the combination of cyproheptadine and bromocriptine was studied in 15 patients with active acromegaly showing incomplete gh suppression in response to bromocriptine therapy alone. |
1989-12-22 |
2023-08-11 |
Not clear |
| C C Chang, F W Chen, H C Hsie. Serum prolactin and growth hormone response to thyrotropin-releasing hormone in patients with pituitary adenomas. Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association. vol 88. issue 5. 1989-11-14. PMID:2507734. |
the dynamics of growth hormone (gh) and prolactin (prl) secretion in response to intravenous 400 micrograms thyrotropin-releasing hormone (trh) in 13 untreated patients with pituitary adenomas (6 women, 7 men; ages 20-64 years; 8 patients with acromegaly, 3 prolactinomas and 2 non-functional adenomas) were correlated with the results of immunohistochemical studies of gh and prl in the adenoma cells. |
1989-11-14 |
2023-08-11 |
Not clear |
| C C Chang, F W Chen, H C Hsie. Serum prolactin and growth hormone response to thyrotropin-releasing hormone in patients with pituitary adenomas. Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association. vol 88. issue 5. 1989-11-14. PMID:2507734. |
the basal serum gh concentrations were abnormally high in 6 and normal in 2 cases of acromegaly. |
1989-11-14 |
2023-08-11 |
Not clear |
| C C Chang, F W Chen, H C Hsie. Serum prolactin and growth hormone response to thyrotropin-releasing hormone in patients with pituitary adenomas. Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association. vol 88. issue 5. 1989-11-14. PMID:2507734. |
one patient with acromegaly and pancreatic islet cell carcinoma had the maximum increment for gh by 303%. |
1989-11-14 |
2023-08-11 |
Not clear |
| O Serri, M Somma, E Rasio, P Brazea. Growth hormone-releasing factor increases serum prolactin concentrations in normal subjects and in patients with pituitary adenomas. Clinical endocrinology. vol 30. issue 1. 1989-10-24. PMID:2505955. |
furthermore, a significant correlation was found between gh rise after grf and basal gh, and between gh rise after grf and gh decrement after sms in patients with acromegaly. |
1989-10-24 |
2023-08-11 |
human |
| S Natori, S Ikuyama, M Haji, M Ohashi, H Nawat. Growth hormone releasing hormone-sensitive adenylate cyclase activity in growth hormone-producing pituitary adenoma: correlation to the response of plasma growth hormone to growth hormone releasing hormone in patients with acromegaly. Endocrinologia japonica. vol 36. issue 2. 1989-10-16. PMID:2550207. |
these results suggest that ghrh-induced gh release from gh-producing pituitary adenomas of patients with acromegaly may be regulated not only by ghrh receptor-adenylate cyclase system but also modified by several other factors including somatostatin and sm-c. |
1989-10-16 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Measurement of nocturnal urinary growth hormone values. Acta endocrinologica. vol 121. issue 2. 1989-10-06. PMID:2672689. |
nocturnal urinary growth hormone values were measured by a sensitive enzyme immunoassay in normal adults, patients with gh deficiency, patients with turner's syndrome, normal but short children who had normal plasma gh responses to provocative tests, and patients with acromegaly. |
1989-10-06 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Measurement of nocturnal urinary growth hormone values. Acta endocrinologica. vol 121. issue 2. 1989-10-06. PMID:2672689. |
the mean nocturnal urinary gh values in patients with acromegaly were significantly greater than those in normal adults (1582.3 +/- 579.8 vs 53.5 +/- 8.6 pmol/mmol creatinine (+/- sem); p less than 0.05). |
1989-10-06 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Measurement of nocturnal urinary growth hormone values. Acta endocrinologica. vol 121. issue 2. 1989-10-06. PMID:2672689. |
these data indicate that nocturnal urinary gh value reflects endogenous gh secretion during collection time, and that measurement of the nocturnal urinary gh values is a useful method for screening of patients with gh deficiency and acromegaly. |
1989-10-06 |
2023-08-11 |
Not clear |
| J Zhang, J M Lu, Z J Huan. Inhibitory effects of atropine on growth hormone release in normal subjects and acromegaly. Chinese medical journal. vol 102. issue 1. 1989-10-03. PMID:2504552. |
in order to study the inhibiting effect of atropine on gh release and whether glucose can be replaced by atropine, normal persons and acromegaly patients were observed during exercise, after atropine, and 100 g glucose loading. |
1989-10-03 |
2023-08-11 |
human |
| J Zhang, J M Lu, Z J Huan. Inhibitory effects of atropine on growth hormone release in normal subjects and acromegaly. Chinese medical journal. vol 102. issue 1. 1989-10-03. PMID:2504552. |
but in acromegaly patients high basal gh levels can not be inhibited by 100 g glucose loading or 0.6 mg atropine during the active phase of the disease. |
1989-10-03 |
2023-08-11 |
human |
| J Zhang, J M Lu, Z J Huan. Inhibitory effects of atropine on growth hormone release in normal subjects and acromegaly. Chinese medical journal. vol 102. issue 1. 1989-10-03. PMID:2504552. |
it is suggested that the atropine test can be used as a gh inhibitory test in acromegaly patients with overt diabetes. |
1989-10-03 |
2023-08-11 |
human |
| C Wang, K S Lam, E Arceo, F L Cha. Comparison of the effectiveness of 2-hourly versus 8-hourly subcutaneous injections of a somatostatin analog (SMS 201-995) in the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 3. 1989-09-15. PMID:2668325. |
to determine whether sc injections of a somatostatin analog (sms 201-995) every 2 h (q2h) is more effective than sc injections every 8 h (q8h) in achieving a constant suppression of gh levels and a more satisfactory clinical response, we studied 10 patients with acromegaly (4 newly diagnosed and 6 previously treated with bromocriptine/pituitary irradiation/transfrontal hypophysectomy). |
1989-09-15 |
2023-08-11 |
human |
| U Vetter, J Zapf, I Henrichs, C Gammert, E Heinze, W Pirsi. Human nasal septal cartilage: analysis of intracellular enzyme activities, glycogen content, cell density and clonal proliferation of septal chondrocytes of healthy adults and acromegalic patients. Connective tissue research. vol 18. issue 4. 1989-08-25. PMID:2526004. |
acromegaly is an endocrine disease due to growth hormone (gh) excess originating from a somatotrophic adenoma of the pituitary gland. |
1989-08-25 |
2023-08-11 |
human |