| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Giusti, A Lomeo, G C Mazzocchi, R Attanasio, P Sessarego, D Mignone, P Fortini, G Giordan. Role of cholinergic receptors blockade by atropine on growth hormone (GH)--releasing hormone (GHRH)--induced GH release in active or surgically cured acromegaly. Minerva endocrinologica. vol 13. issue 2. 1988-11-03. PMID:3139980. |
role of cholinergic receptors blockade by atropine on growth hormone (gh)--releasing hormone (ghrh)--induced gh release in active or surgically cured acromegaly. |
1988-11-03 |
2023-08-11 |
Not clear |
| R Yamasaki, H Saito, T Sano, K Kameyama, K Yoshimoto, E Hosoi, M Matsumura, K Harada, S Sait. Ectopic growth hormone-releasing hormone (GHRH) syndrome in a case with multiple endocrine neoplasia type I. Endocrinologia japonica. vol 35. issue 1. 1988-09-06. PMID:2899505. |
these results indicate that 1) a moderate increase in circulating ghrh due to ectopic secretion from a pancreatic tumor stimulated gh secretion resulting in acromegaly, and evoked gh responses to various provocative tests indistinguishable from those in patients with classical acromegaly, and 2) the ectopic secretion of ghrh may play an etiological role in the pituitary lesion of this patient with men type i. |
1988-09-06 |
2023-08-11 |
Not clear |
| S Melmed, F H Ziel, G D Braunstein, T Downs, L A Frohma. Medical management of acromegaly due to ectopic production of growth hormone-releasing hormone by a carcinoid tumor. The Journal of clinical endocrinology and metabolism. vol 67. issue 2. 1988-08-24. PMID:2899089. |
she had previously undergone a hypophysectomy for acromegaly and an enlarged pituitary, with a reduction in her serum gh levels from 100 to 4 micrograms/l. |
1988-08-24 |
2023-08-11 |
Not clear |
| S Melmed, F H Ziel, G D Braunstein, T Downs, L A Frohma. Medical management of acromegaly due to ectopic production of growth hormone-releasing hormone by a carcinoid tumor. The Journal of clinical endocrinology and metabolism. vol 67. issue 2. 1988-08-24. PMID:2899089. |
treatment with pergolide initially resulted in reduction in serum gh and igf-i levels and amelioration of symptoms of acromegaly. |
1988-08-24 |
2023-08-11 |
Not clear |
| K Hall, G Lundin, G Póvo. Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa. Acta endocrinologica. vol 118. issue 3. 1988-08-17. PMID:2455950. |
the mean level of the 35 kd igfbp in patients with acromegaly (19 micrograms/l, n = 23) was decreased by 50% in comparison with healthy adults, whereas a 2-fold elevation of the mean levels was found in both anorexia nervosa patients (70 micrograms/l, n = 13) and adult patients with gh deficiency (69 micrograms/l, n = 22). |
1988-08-17 |
2023-08-11 |
human |
| J A Ramsay, K Kovacs, S L Asa, M J Pike, M O Thorne. Reversible sellar enlargement due to growth hormone-releasing hormone production by pancreatic endocrine tumors in a acromegalic patient with multiple endocrine neoplasia type I syndrome. Cancer. vol 62. issue 2. 1988-08-10. PMID:2898285. |
the clinicopathologic findings indicate that, in patients with multiple endocrine neoplasia type i (men-i), grh production by pancreatic tumors can stimulate hypophysial somatotrophs resulting in gh excess and acromegaly due to a reversible pituitary lesion, most likely somatotroph hyperplasia. |
1988-08-10 |
2023-08-11 |
Not clear |
| A L Barkan, I Z Beitins, R P Kelc. Plasma insulin-like growth factor-I/somatomedin-C in acromegaly: correlation with the degree of growth hormone hypersecretion. The Journal of clinical endocrinology and metabolism. vol 67. issue 1. 1988-07-28. PMID:2897974. |
we measured plasma insulin-like growth factor i/somatomedin-c (igf-i/smc) concentrations and mean 24-h gh secretion serially before and during therapy with the long-acting somatostatin analog sms 201-995 in 21 patients with acromegaly. |
1988-07-28 |
2023-08-11 |
Not clear |
| A L Barkan, I Z Beitins, R P Kelc. Plasma insulin-like growth factor-I/somatomedin-C in acromegaly: correlation with the degree of growth hormone hypersecretion. The Journal of clinical endocrinology and metabolism. vol 67. issue 1. 1988-07-28. PMID:2897974. |
we conclude that 1) an excellent log dose-response correlation between mean 24-h plasma gh and igf-i/smc concentrations is present in patients with acromegaly; 2) normalization of plasma igf-i/smc occurs only in patients with mean daily gh output within the normal range; and 3) determination of plasma igf-i/smc is an accurate indicator of normalcy of gh secretion and should be used in the diagnosis of active acromegaly as well as in monitoring the progress of therapy. |
1988-07-28 |
2023-08-11 |
Not clear |
| R Yamasaki, H Saito, K Kameyama, E Hosoi, S Sait. Secretion of growth hormone-releasing hormone in patients with idiopathic pituitary dwarfism and acromegaly. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:2898191. |
in 3 untreated patients with acromegaly l-dopa did not induce any response of plasma ghrh in spite of inconsistent gh release, and in 4 patients with acromegaly, trh evoked no response of plasma ghrh in spite of a marked gh release, suggesting that the gh responses are not mediated by hypothalamic ghrh. |
1988-07-27 |
2023-08-11 |
Not clear |
| A E Smals, G F Pieters, A G Smals, P W Kloppenbor. Sex difference in the relation between sellar volume and basal and GH-releasing hormone stimulated GH in acromegaly. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:3132795. |
sex difference in the relation between sellar volume and basal and gh-releasing hormone stimulated gh in acromegaly. |
1988-07-27 |
2023-08-11 |
Not clear |
| A E Smals, G F Pieters, A G Smals, P W Kloppenbor. Sex difference in the relation between sellar volume and basal and GH-releasing hormone stimulated GH in acromegaly. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:3132795. |
sellar volume and both basal (r = +0.54, p less than 0.02) and ghrh-stimulated (r = +0.41, p less than 0.05) gh levels were directly correlated in a group of 28 patients with acromegaly as were the latter indices (r = +0.82, p less than 0.001). |
1988-07-27 |
2023-08-11 |
Not clear |
| A E Smals, G F Pieters, A G Smals, P W Kloppenbor. Sex difference in the relation between sellar volume and basal and GH-releasing hormone stimulated GH in acromegaly. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:3132795. |
the presence of a tight relation between sellar volume and basal and ghrh stimulated gh levels in male patients with acromegaly and its complete absence in women are equally intriguing and await further elucidation. |
1988-07-27 |
2023-08-11 |
Not clear |
| P C Hindmarsh, P J Pringle, C G Broo. The 24-hour growth hormone secretion in a boy with giantism. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:3132796. |
a 24-h gh profile demonstrated a persistently elevated gh concentration (mean gh concentration: giant 19.3 mu/l; tall boy 5.4 mu/l) with loss of the dominant gh periodicity of 3 h seen in the boy with tall stature and substitution with one of 8 h. these data support the view that giantism and acromegaly are similar diseases occurring prior to and following epiphyseal fusion, respectively. |
1988-07-27 |
2023-08-11 |
Not clear |
| J Rovensky, J Marek, O Schreiberová, O Hníková, M Vigas, B Strindberg, P Luká. Effect of human growth hormone and somatomedin on the recovery of sheep red blood cell receptor in peripheral T-lymphocytes. Endocrinologia experimentalis. vol 22. issue 1. 1988-07-14. PMID:3259505. |
the effect of growth hormone (gh) and somatomedin (sm) on the recovery of sheep red blood cell (srbc) receptor in trypsinized human t-lymphocytes was studied either with the use of sera from patients with acromegaly or pituitary dwarfism or after the addition of exogenous gh, sm or thymosin to human sera. |
1988-07-14 |
2023-08-11 |
human |
| G Knappe, V Hesse, G Jahreis, W Rohde, H Ger. Somatomedin-C in active and successfully treated acromegaly. Experimental and clinical endocrinology. vol 91. issue 1. 1988-07-14. PMID:3371416. |
sm-c determinations are judged as a good adjunct to usual diagnostic methods which in special cases of acromegaly can be even superior to measurements of serum gh. |
1988-07-14 |
2023-08-11 |
Not clear |
| J Lindholm, B Giwercman, A Giwercman, J Astrup, P Bjerre, N E Skakkebae. Investigation of the criteria for assessing the outcome of treatment in acromegaly. Clinical endocrinology. vol 27. issue 5. 1988-07-05. PMID:3450453. |
the outcome of treatment in acromegaly is usually assessed by measuring plasma concentrations of growth hormone (gh)--either basal spontaneous levels or during hyperglycaemia. |
1988-07-05 |
2023-08-11 |
Not clear |
| J Lindholm, B Giwercman, A Giwercman, J Astrup, P Bjerre, N E Skakkebae. Investigation of the criteria for assessing the outcome of treatment in acromegaly. Clinical endocrinology. vol 27. issue 5. 1988-07-05. PMID:3450453. |
very low plasma gh levels (less than 1 mu/l or 0.5 ng/ml) were associated with normal smc values and clinical cure, high gh levels (greater than 10 mu/l or 5 ng/ml) with elevated smc levels and persisting acromegaly. |
1988-07-05 |
2023-08-11 |
Not clear |
| K Nakagawa, K Akikawa, M Matsubara, M Kubo, T Ishizuka, T Obar. Biphasic effects of dexamethasone on growth hormone release in vitro. Endocrinologia japonica. vol 34. issue 6. 1988-06-28. PMID:2836185. |
the effect of dexamethasone (dex) on growth hormone (gh) release was examined in vitro in monolayer culture of normal rat pituitary cells and human somatotropinoma cells from patients with acromegaly. |
1988-06-28 |
2023-08-11 |
human |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3286672. |
daily (24-h) urinary gh excretion was measured using a highly sensitive sandwich enzyme immunoassay in 10 normal adults, 6 patients with hypopituitarism, 25 normal but short children who had normal plasma gh responses (peak plasma gh level, greater than 10 micrograms/l) to provocative tests, and 8 patients with acromegaly. |
1988-06-28 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3286672. |
the mean urinary gh values in the normal adults, patients with acromegaly, and patients with hypopituitarism were 13.8 +/- 4.0 (+/- se) and 431.1 +/- 149.1 ng/g creatinine (cr) (1.56 +/- 0.45 and 48.77 +/- 16.87 ng/mmol cr) and undetectable, respectively; these mean values were significantly different from each other. |
1988-06-28 |
2023-08-11 |
Not clear |