| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Nakagawa, K Akikawa, M Matsubara, M Kubo, T Ishizuka, T Obar. Biphasic effects of dexamethasone on growth hormone release in vitro. Endocrinologia japonica. vol 34. issue 6. 1988-06-28. PMID:2836185. |
the effect of dexamethasone (dex) on growth hormone (gh) release was examined in vitro in monolayer culture of normal rat pituitary cells and human somatotropinoma cells from patients with acromegaly. |
1988-06-28 |
2023-08-11 |
human |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3286672. |
daily (24-h) urinary gh excretion was measured using a highly sensitive sandwich enzyme immunoassay in 10 normal adults, 6 patients with hypopituitarism, 25 normal but short children who had normal plasma gh responses (peak plasma gh level, greater than 10 micrograms/l) to provocative tests, and 8 patients with acromegaly. |
1988-06-28 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3286672. |
the mean urinary gh values in the normal adults, patients with acromegaly, and patients with hypopituitarism were 13.8 +/- 4.0 (+/- se) and 431.1 +/- 149.1 ng/g creatinine (cr) (1.56 +/- 0.45 and 48.77 +/- 16.87 ng/mmol cr) and undetectable, respectively; these mean values were significantly different from each other. |
1988-06-28 |
2023-08-11 |
Not clear |
| I Sukegawa, N Hizuka, K Takano, K Asakawa, R Horikawa, S Hashida, E Ishikawa, Z Mohri, Y Murakami, K Shizum. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3286672. |
in 6 patients with acromegaly whose plasma gh levels were constant throughout a 4-h period, the urinary gh values also significantly correlated with the mean plasma gh levels (r = 0.95; p less than 0.01). |
1988-06-28 |
2023-08-11 |
Not clear |
| E Horvath, K Kovacs, H S Smyth, D W Killinger, B W Scheithauer, R Randall, E R Laws, W Singe. A novel type of pituitary adenoma: morphological features and clinical correlations. The Journal of clinical endocrinology and metabolism. vol 66. issue 6. 1988-06-28. PMID:3372677. |
three men had elevated serum gh levels and acromegaly, suggestive of multidirectional differentiation. |
1988-06-28 |
2023-08-11 |
Not clear |
| D A Ross, C B Wilso. Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients. Journal of neurosurgery. vol 68. issue 6. 1988-06-24. PMID:3373281. |
of 214 patients with acromegaly who underwent transsphenoidal microsurgical resection of a pituitary adenoma, 54% had growth hormone (gh) levels below 5 ng/ml and 74% had levels less than 10 ng/ml immediately after surgery. |
1988-06-24 |
2023-08-11 |
Not clear |
| D Giannella-Neto, B L Wajchenberg, B B Mendonça, S F Almeida, M Macchione, E M Spence. Criteria for the cure of acromegaly: comparison between basal growth hormone and somatomedin C plasma concentrations in active and non-active acromegalic patients. Journal of endocrinological investigation. vol 11. issue 1. 1988-06-09. PMID:3361077. |
fasting plasma growth hormone (gh) and somatomedin c (smc) levels were compared as criteria for the cure of acromegaly in 7 untreated and 16 treated acromegalic patients studied 1 to 16 yr after pituitary surgery and/or radiotherapy. |
1988-06-09 |
2023-08-11 |
human |
| D Giannella-Neto, B L Wajchenberg, B B Mendonça, S F Almeida, M Macchione, E M Spence. Criteria for the cure of acromegaly: comparison between basal growth hormone and somatomedin C plasma concentrations in active and non-active acromegalic patients. Journal of endocrinological investigation. vol 11. issue 1. 1988-06-09. PMID:3361077. |
the subjects with active acromegaly (both treated and untreated) presenting gh higher than 5 ng/ml did not show any correlation between gh and smc levels. |
1988-06-09 |
2023-08-11 |
human |
| W Saeger, P Kant, J Caselitz, D K Lüdeck. Electron microscopical morphometry of pituitary adenomas. Comparison of tumours in acromegaly and hyperprolactinemia. Pathology, research and practice. vol 183. issue 1. 1988-06-02. PMID:3362748. |
the 4 types of adenomas were characterized by the following features: group i: acromegaly without hyperprolactinemia (gh positive and prl negative on the immunohistochemical level); group ii: acromegaly with hyperprolactinemia and/or galactorrhea (gh positive and prl positive on the immunohistochemical level); group iii: adenomas with hyperprolactinemia without acromegaly (gh negative and prl positive on the immunohistochemical level); group iv: adenomas with hyperprolactinemia without acromegaly (gh and prl negative on the immunohistochemical level). |
1988-06-02 |
2023-08-11 |
Not clear |
| B Ferramosca, D Bianchi, D Serra, R Savini, A S Villecco, R Bugiardin. [Cardiological findings in acromegaly]. Minerva medica. vol 78. issue 24. 1988-03-15. PMID:3431727. |
in order to assess the existence and course of subclinical cardiac alterations, 8 acromegaly patients were examined: 4 males and 4 females aged 31-56 with gh levels of 24-70 ng/ml (m + cd x 47 +/- 16) and no cardiovascular symptoms. |
1988-03-15 |
2023-08-11 |
Not clear |
| S Mitsuhashi, R Yamasaki, S Miyazaki, H Saito, S Sait. [Effect of oral administration of L-dopa on the plasma levels of growth hormone-releasing hormone (GHRH) in normal subjects and patients with various endocrine and metabolic diseases]. Nihon Naibunpi Gakkai zasshi. vol 63. issue 8. 1988-03-04. PMID:3123283. |
in patients with acromegaly, the plasma levels of ghrh remained stationary after the l-dopa administration and did not correlate with plasma gh levels. |
1988-03-04 |
2023-08-11 |
human |
| G Bauman. Acromegaly. Endocrinology and metabolism clinics of North America. vol 16. issue 3. 1988-02-09. PMID:3319599. |
acromegaly is caused by gh-secreting pituitary adenomas and, in rare cases, by ectopic production of grh with resultant hypersecretion of gh. |
1988-02-09 |
2023-08-11 |
Not clear |
| A L Barkan, R P Kelch, N J Hopwood, I Z Beitin. Treatment of acromegaly with the long-acting somatostatin analog SMS 201-995. The Journal of clinical endocrinology and metabolism. vol 66. issue 1. 1988-02-02. PMID:2891720. |
current treatment of acromegaly (surgery, radiation, and bromocriptine) is often unsatisfactory, and a sizeable proportion of patients with this disease continue to have gh hypersecretion after all therapeutic modalities have been exhausted. |
1988-02-02 |
2023-08-11 |
Not clear |
| P E Belchet. Growth hormone responses to hp GRF 1-44 amide, bromocriptine and stress in acromegaly are correlated. Postgraduate medical journal. vol 63. issue 738. 1988-01-12. PMID:3120167. |
a hypothesis is proposed to explain these findings on the basis of varying degrees of gh secretion from adenomatous and normal pituitary somatotrophs in acromegaly. |
1988-01-12 |
2023-08-11 |
human |
| M Daniels, M C White, P Kendall-Taylo. Long-term in-vitro maintenance of growth hormone secretion from human somatotrophinomas with cortisol, and its effects on growth hormone-releasing factor. The Journal of endocrinology. vol 114. issue 3. 1987-12-15. PMID:3117958. |
the effect of cortisol (206 nmol/l) on gh secretion from enzymatically dispersed human somatotrophinoma cells in long-term culture was studied using adenomas from 13 patients with acromegaly. |
1987-12-15 |
2023-08-11 |
human |
| S W Lamberts, P Uitterlinden, T Verleu. Relationship between growth hormone and somatomedin-C levels in untreated acromegaly, after surgery and radiotherapy and during medical therapy with sandostatin (SMS 201-995). European journal of clinical investigation. vol 17. issue 4. 1987-12-08. PMID:2889603. |
several conflicting reports have been published with regard to the relationships between circulating growth hormone (gh), somatomedin-c (sm-c) levels and clinical activity during different stages of therapy of acromegaly. |
1987-12-08 |
2023-08-11 |
Not clear |
| C Zurschmiede, A M Landol. Distribution of growth hormone and prolactin in secretory granules of the normal and neoplastic human adenohypophysis. Virchows Archiv. B, Cell pathology including molecular pathology. vol 53. issue 5. 1987-11-17. PMID:2889294. |
the number of gh-containing granules (pure gh granules and mixed gh-prl granules) was greater than that of prl-containing granules (pure prl granules and mixed prl-gh granules) in adenomas causing acromegaly and in the normal pituitary tissue, whereas the opposite was true for prolactinomas. |
1987-11-17 |
2023-08-11 |
human |
| A E Smals, G F Pieters, A G Smals, A R Hermus, T J Benraad, P W Kloppenbor. The higher the growth hormone response to growth hormone releasing hormone the lower the response to bromocriptine and thyrotrophin releasing hormone in acromegaly. Clinical endocrinology. vol 27. issue 1. 1987-11-12. PMID:3115634. |
in acromegaly a direct relationship has been demonstrated between gh responsiveness to trh and to the dopaminergic agent bromocriptine (br). |
1987-11-12 |
2023-08-11 |
Not clear |
| W Saeger, K Rübenach-Gerz, J Caselitz, D K Lüdeck. Electron microscopical morphometry of GH producing pituitary adenomas in comparison with normal GH cells. Virchows Archiv. A, Pathological anatomy and histopathology. vol 411. issue 5. 1987-11-12. PMID:3116761. |
gh producing adenomas of patients with acromegaly (undifferentiated acidophil adenomas and well differentiated gh cell adenomas) were studied at the ultrastructural level and analysed morphometrically by the point counting method. |
1987-11-12 |
2023-08-11 |
Not clear |
| J Timsit, P Chanson, E Larger, M Duet, A Mosse, P J Guillausseau, A G Harris, M Moulonguet, A Warnet, J Lubetzk. The effect of subcutaneous infusion versus subcutaneous injections of a somatostatin analogue (SMS 201-995) on the diurnal GH profile in acromegaly. Acta endocrinologica. vol 116. issue 1. 1987-11-10. PMID:2889306. |
the effect of subcutaneous infusion versus subcutaneous injections of a somatostatin analogue (sms 201-995) on the diurnal gh profile in acromegaly. |
1987-11-10 |
2023-08-11 |
Not clear |