| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Baumann, M A Shaw, K Ambur. Regulation of plasma growth hormone-binding proteins in health and disease. Metabolism: clinical and experimental. vol 38. issue 7. 1989-08-10. PMID:2739578. |
the conditions were selected to provide basic physiologic data (men, women, children, age, pregnancy and to investigate key disease states attended by abnormal gh physiology (liver cirrhosis, uremia, infection, acromegaly). |
1989-08-10 |
2023-08-11 |
human |
| S Nishida, M Matsuki, N Adachi, M Horino, K Tsushima, M Yoneda, H Oyama, R Otsuka, M Kikuoka, Y Ogaw. Provocation of a paradoxical growth hormone response to corticotropin-releasing hormone by pretreatment with metoclopramide in patients with acromegaly and normal subjects. Endocrinologia japonica. vol 35. issue 6. 1989-07-18. PMID:3266935. |
two of 7 patients with acromegaly and one of 7 normal subjects exhibited a paradoxical rise in growth hormone (gh) to human corticotropin-releasing hormone (crh) when pretreated with metoclopramide, although crh alone did not induce an increase in gh. |
1989-07-18 |
2023-08-11 |
human |
| S Nishida, M Matsuki, N Adachi, M Horino, K Tsushima, M Yoneda, H Oyama, R Otsuka, M Kikuoka, Y Ogaw. Provocation of a paradoxical growth hormone response to corticotropin-releasing hormone by pretreatment with metoclopramide in patients with acromegaly and normal subjects. Endocrinologia japonica. vol 35. issue 6. 1989-07-18. PMID:3266935. |
in one of these two patients with acromegaly, the gh increase to metoclopramide alone also reached the criteria of a paradoxical response. |
1989-07-18 |
2023-08-11 |
human |
| S Nishida, M Matsuki, N Adachi, M Horino, K Tsushima, M Yoneda, H Oyama, R Otsuka, M Kikuoka, Y Ogaw. Provocation of a paradoxical growth hormone response to corticotropin-releasing hormone by pretreatment with metoclopramide in patients with acromegaly and normal subjects. Endocrinologia japonica. vol 35. issue 6. 1989-07-18. PMID:3266935. |
it is suggested from these results that the gh response to metoclopramide and the metoclopramide-provoked gh response to crh in patients with acromegaly result from the secretion of gh from nonadenomatous cells of the pituitary. |
1989-07-18 |
2023-08-11 |
human |
| S Ohgo, E Ishikawa, K Nakatsuru, K Kinoshita, S Matsukur. Comparative in vivo and in vitro studies on abnormal GH secretion in patients with acromegaly. Endocrinologia japonica. vol 36. issue 1. 1989-07-14. PMID:2499448. |
comparative in vivo and in vitro studies on abnormal gh secretion in patients with acromegaly. |
1989-07-14 |
2023-08-11 |
Not clear |
| L De Marinis, A Mancini, A La Brocca, C D'Amico, P Sambo, A Tofani, A Barbarin. [Growth hormone-releasing hormone. The physiopathologic aspects and its diagnostic-therapeutic use]. Minerva medica. vol 80. issue 4. 1989-07-13. PMID:2566960. |
in the second section is attracted attention on the ghrh as a diagnostic agent in the two diseases that represent the main alterations of the gh secretion: acromegaly and short stature. |
1989-07-13 |
2023-08-11 |
human |
| L Cuttler, J A Jackson, M Saeed uz-Zafar, L L Levitsky, R C Mellinger, L A Frohma. Hypersecretion of growth hormone and prolactin in McCune-Albright syndrome. The Journal of clinical endocrinology and metabolism. vol 68. issue 6. 1989-06-30. PMID:2498385. |
acromegaly and hyperprolactinemia have been reported in association with the mccune-albright syndrome, but the pathophysiology of the gh and prl hypersecretion that occurs in patients with this disorder has not been defined. |
1989-06-30 |
2023-08-11 |
Not clear |
| L Cuttler, J A Jackson, M Saeed uz-Zafar, L L Levitsky, R C Mellinger, L A Frohma. Hypersecretion of growth hormone and prolactin in McCune-Albright syndrome. The Journal of clinical endocrinology and metabolism. vol 68. issue 6. 1989-06-30. PMID:2498385. |
however, the lack of radiographic pituitary enlargement, the variable pituitary pathology reported in similar patients, and frequent concordance of gh and prl excess suggest that the pathogenesis of this disorder may differ fundamentally from other forms of acromegaly or gigantism. |
1989-06-30 |
2023-08-11 |
Not clear |
| M D Katz, B L Ersta. Octreotide, a new somatostatin analogue. Clinical pharmacy. vol 8. issue 4. 1989-06-22. PMID:2653711. |
octreotide therapy lowers gh secretion and improves clinical symptoms in patients with acromegaly and may suppress clinical symptoms to a greater degree than bromocriptine. |
1989-06-22 |
2023-08-11 |
Not clear |
| W B Malarkey, K Kovacs, T M O'Dorisi. Response of a GH- and TSH-secreting pituitary adenoma to a somatostatin analogue (SMS 201-995): evidence that GH and TSH coexist in the same cell and secretory granules. Neuroendocrinology. vol 49. issue 3. 1989-06-19. PMID:2716953. |
a 29-year-old male presented with acromegaly and hyperthyroidism and was found to be hypersecreting both gh and tsh. |
1989-06-19 |
2023-08-11 |
Not clear |
| W B Malarkey, K Kovacs, T M O'Dorisi. Response of a GH- and TSH-secreting pituitary adenoma to a somatostatin analogue (SMS 201-995): evidence that GH and TSH coexist in the same cell and secretory granules. Neuroendocrinology. vol 49. issue 3. 1989-06-19. PMID:2716953. |
thus it can be concluded that pituitary adenomas can simultaneously secrete gh and tsh which produce acromegaly and hyperthyroidism. |
1989-06-19 |
2023-08-11 |
Not clear |
| D K Lüdecke, B S Lutz, G Niedworo. The choice of treatment after incomplete adenomectomy in acromegaly: proton--versus high voltage radiation. Acta neurochirurgica. vol 96. issue 1-2. 1989-05-11. PMID:2539000. |
the authors report the results of a study designed to compare the effectiveness of two different types of radiation in patients with acromegaly where surgical therapy had failed to normalize growth hormone (gh). |
1989-05-11 |
2023-08-11 |
Not clear |
| J Trouillas, C Girod, B Loras, B Claustrat, G Sassolas, G Perrin, R Buonaguid. The TSH secretion in the human pituitary adenomas. Pathology, research and practice. vol 183. issue 5. 1989-05-03. PMID:3237550. |
in a majority of the cases, the tumoral tsh secretion induced hyperthyroidism but in 2 patients with tsh adenoma there was euthyroidism and in another with tsh-gh adenoma there was no sign of acromegaly and gh serum levels were normal. |
1989-05-03 |
2023-08-11 |
human |
| M Losa, J Alba-Roth, S Sobieszczyk, J Schopohl, O A Müller, K von Werde. Effects of repetitive administration of thyrotropin-releasing hormone at short intervals in acromegaly. Acta endocrinologica. vol 120. issue 3. 1989-04-21. PMID:2494827. |
we investigated the pattern of gh secretion in response to repetitive trh administration in patients with active acromegaly and in normal subjects. |
1989-04-21 |
2023-08-11 |
human |
| J Y Li, O Racadot, M Kujas, M Kouadri, F Peillon, J Racado. Immunocytochemistry of four mixed pituitary adenomas and intrasellar gangliocytomas associated with different clinical syndromes: acromegaly, amenorrhea-galactorrhea, Cushing's disease and isolated tumoral syndrome. Acta neuropathologica. vol 77. issue 3. 1989-04-18. PMID:2922994. |
these findings show that: (i) in three cases, pituitary hormones (prl and acth), and, in one case, vip could be localized in both adenomatous and ganglion cells; (ii) the pituitary hormone-containing cells in the tumors could be related to the hypersecretory syndromes; (iii) intratumoral ir-vip and -grh might be involved in gh and prl hypersecretion in the cases with acromegaly and amenorrhea-galactorrhea. |
1989-04-18 |
2023-08-11 |
Not clear |
| R V Lloyd, M Cano, W F Chandler, A L Barkan, E Horvath, K Kovac. Human growth hormone and prolactin secreting pituitary adenomas analyzed by in situ hybridization. The American journal of pathology. vol 134. issue 3. 1989-04-11. PMID:2466405. |
patients with a clinical diagnosis of prolactinoma had cells with only prl mrna in their tumors, while most (14 of 16) patients with a clinical diagnosis of acromegaly or gigantism had both gh and prl mrnas in their tumors. |
1989-04-11 |
2023-08-11 |
human |
| R V Lloyd, M Cano, W F Chandler, A L Barkan, E Horvath, K Kovac. Human growth hormone and prolactin secreting pituitary adenomas analyzed by in situ hybridization. The American journal of pathology. vol 134. issue 3. 1989-04-11. PMID:2466405. |
in situ hybridization was helpful in characterizing the adenoma from a patient with acromegaly who had immunoreactive prl, but no immunoreactive gh in the resected tumor; in situ hybridization analysis revealed mrnas for both gh and prl in the same tumor cells. |
1989-04-11 |
2023-08-11 |
human |
| D E Moller, A C Moses, K Jones, M O Thorner, M L Vanc. Octreotide suppresses both growth hormone (GH) and GH-releasing hormone (GHRH) in acromegaly due to ectopic GHRH secretion. The Journal of clinical endocrinology and metabolism. vol 68. issue 2. 1989-03-27. PMID:2493033. |
octreotide suppresses both growth hormone (gh) and gh-releasing hormone (ghrh) in acromegaly due to ectopic ghrh secretion. |
1989-03-27 |
2023-08-11 |
Not clear |
| M Losa, J Alba-Lopez, J Schopohl, S Sobiesczcyk, P G Chiodini, O A Müller, K von Werde. Effects of theophylline infusion on the growth hormone (GH) and prolactin response to GH-releasing hormone administration in acromegaly. Journal of endocrinological investigation. vol 11. issue 9. 1989-03-23. PMID:3146595. |
effects of theophylline infusion on the growth hormone (gh) and prolactin response to gh-releasing hormone administration in acromegaly. |
1989-03-23 |
2023-08-11 |
human |
| M Losa, J Alba-Lopez, J Schopohl, S Sobiesczcyk, P G Chiodini, O A Müller, K von Werde. Effects of theophylline infusion on the growth hormone (GH) and prolactin response to GH-releasing hormone administration in acromegaly. Journal of endocrinological investigation. vol 11. issue 9. 1989-03-23. PMID:3146595. |
since theophylline has been shown to blunt the gh response to growth hormone-releasing hormone (ghrh) in normal subjects, we investigated whether the same effect of theophylline administration could be reproduced in patients with active acromegaly. |
1989-03-23 |
2023-08-11 |
human |