| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Watanobe, S Sasaki, K Takeb. Failure to confirm a growth hormone-releasing activity of corticotropin-releasing hormone in acromegaly: comparison with the effects of other hypothalamic hormones. Acta endocrinologica. vol 125. issue 5. 1992-02-05. PMID:1759537. |
human crh (100 micrograms) was given as an iv bolus to 15 patients with active acromegaly, and plasma gh levels were measured before and at intervals up to 120 min after the injection. |
1992-02-05 |
2023-08-11 |
human |
| H Watanobe, S Sasaki, K Takeb. Failure to confirm a growth hormone-releasing activity of corticotropin-releasing hormone in acromegaly: comparison with the effects of other hypothalamic hormones. Acta endocrinologica. vol 125. issue 5. 1992-02-05. PMID:1759537. |
for comparison, we assessed in all the patients the effects of trh (500 micrograms), gnrh (100 micrograms), vasoactive intestinal peptide (100 micrograms) and peptide histidine methionine (100 micrograms), which are known paradoxically to stimulate gh secretion in acromegaly. |
1992-02-05 |
2023-08-11 |
human |
| W Zh. [Echocardiographic changes in 91 patients with acromegaly]. Zhonghua yi xue za zhi. vol 71. issue 9. 1992-01-23. PMID:1660776. |
76 patients with active acromegaly (gh greater than 5 ng/ml) were analysed. |
1992-01-23 |
2023-08-11 |
Not clear |
| M Thorén, T Rähn, W Y Guo, S Werne. Stereotactic radiosurgery with the cobalt-60 gamma unit in the treatment of growth hormone-producing pituitary tumors. Neurosurgery. vol 29. issue 5. 1992-01-08. PMID:1961394. |
stereotactic radiosurgery on the pituitary given with the cobalt-60 gamma unit was used in the treatment of 21 patients with growth hormone (gh)-producing pituitary adenomas and acromegaly. |
1992-01-08 |
2023-08-11 |
Not clear |
| S Melme. Extrapituitary acromegaly. Endocrinology and metabolism clinics of North America. vol 20. issue 3. 1991-12-26. PMID:1935918. |
acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (ghrh), or growth hormone (gh) itself. |
1991-12-26 |
2023-08-11 |
Not clear |
| E Ritz, B Tönshoff, S Worgall, G Kovacs, O Mehl. Influence of growth hormone and insulin-like growth factor-I on kidney function and kidney growth. Pediatric nephrology (Berlin, Germany). vol 5. issue 4. 1991-11-14. PMID:1911130. |
decreased glomerular filtration rate (gfr) in hypopituitarism and increased gfr in acromegaly suggest that growth hormone (gh) has a substantial effect on renal haemodynamics. |
1991-11-14 |
2023-08-11 |
mouse |
| W Saeger, H Uhlig, E Bäz, S Fehr, D K Lüdeck. In situ hybridization for different mRNA in GH-secreting and in inactive pituitary adenomas. Pathology, research and practice. vol 187. issue 5. 1991-11-14. PMID:1923947. |
in a series of 40 pituitary adenomas in acromegaly all tumors showed mrna for gh by in situ hybridization (ish). |
1991-11-14 |
2023-08-11 |
Not clear |
| A Behncken, W Saege. Lectin-bindings in pituitary adenomas and normal pituitaries. Pathology, research and practice. vol 187. issue 5. 1991-11-14. PMID:1923958. |
via statistical analysis, correlating lectin-bindings with clinical hyperfunction and immunohistochemical hormone content, we found an association of acromegaly and pna and cona and of cushing's disease and pna and uea-1; furthermore of gh and uea-1 and con-a, of tsh and uea-1 and of acth and pna and uea-1. |
1991-11-14 |
2023-08-11 |
Not clear |
| M Mori, T Satoh, K Miyashita, M Yamada, M Murakami, T Iriuchijima, K Ohshima, I Kobayashi, S Kobayash. TRH-Gly, a precursor of TRH, alters GH secretion in acromegaly. Life sciences. vol 49. issue 14. 1991-10-17. PMID:1909766. |
trh-gly, a precursor of trh, alters gh secretion in acromegaly. |
1991-10-17 |
2023-08-11 |
Not clear |
| M Mori, T Satoh, K Miyashita, M Yamada, M Murakami, T Iriuchijima, K Ohshima, I Kobayashi, S Kobayash. TRH-Gly, a precursor of TRH, alters GH secretion in acromegaly. Life sciences. vol 49. issue 14. 1991-10-17. PMID:1909766. |
we explored effects of a precursor of thyrotropin (tsh)-releasing hormone (trh), trh-gly, on growth hormone (gh) secretion in acromegaly. |
1991-10-17 |
2023-08-11 |
Not clear |
| M Mori, T Satoh, K Miyashita, M Yamada, M Murakami, T Iriuchijima, K Ohshima, I Kobayashi, S Kobayash. TRH-Gly, a precursor of TRH, alters GH secretion in acromegaly. Life sciences. vol 49. issue 14. 1991-10-17. PMID:1909766. |
the present data suggest that trh-gly may participate in regulating gh secretion in some patients with acromegaly and that trh-gly-induced gh secretion may be due at least in part to trh-associated mechanisms underlying gh secretion. |
1991-10-17 |
2023-08-11 |
Not clear |
| J M Holly, A M Cotterill, R C Jemmott, D Shears, S al-Othman, T Chard, J A Was. Inter-relations between growth hormone, insulin, insulin-like growth factor-I (IGF-I), IGF-binding protein-1 (IGFBP-1) and sex hormone-binding globulin in acromegaly. Clinical endocrinology. vol 34. issue 4. 1991-10-03. PMID:1715247. |
acromegaly is characterized by a hypersecretion of gh, which in turn results in an excess of igf-i, an important mediator of its actions. |
1991-10-03 |
2023-08-11 |
human |
| J M Holly, A M Cotterill, R C Jemmott, D Shears, S al-Othman, T Chard, J A Was. Inter-relations between growth hormone, insulin, insulin-like growth factor-I (IGF-I), IGF-binding protein-1 (IGFBP-1) and sex hormone-binding globulin in acromegaly. Clinical endocrinology. vol 34. issue 4. 1991-10-03. PMID:1715247. |
we have examined the inter-relations between gh, prolactin, insulin, igf-i and one of the binding proteins, igfbp-1, in 62 patients with acromegaly of varying activity. |
1991-10-03 |
2023-08-11 |
human |
| J M Holly, A M Cotterill, R C Jemmott, D Shears, S al-Othman, T Chard, J A Was. Inter-relations between growth hormone, insulin, insulin-like growth factor-I (IGF-I), IGF-binding protein-1 (IGFBP-1) and sex hormone-binding globulin in acromegaly. Clinical endocrinology. vol 34. issue 4. 1991-10-03. PMID:1715247. |
even in subjects whose acromegaly was well controlled or cured, as indicated by gh levels of less than 1 mu/l or igf-i levels of less than 2 u/ml, fasting insulin levels remained significantly elevated in some individuals. |
1991-10-03 |
2023-08-11 |
human |
| M J Saad, A C Moreira, M C Fos. Endogenous hyperinsulinemia and release of growth hormone following a glucose load as well as in response to thyrotropin releasing hormone in acromegaly. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 23. issue 10. 1991-09-05. PMID:2129261. |
these data suggest that the endogenous hyperinsulinemia exhibited by many patients with acromegaly is associated with the absence of the paradoxical increase in gh secretion during the ogtt and/or after trh. |
1991-09-05 |
2023-08-11 |
human |
| S Ezzat, S G Ren, G D Braunstein, S Melme. Octreotide stimulates insulin-like growth factor binding protein-1 (IGFBP-1) levels in acromegaly. The Journal of clinical endocrinology and metabolism. vol 73. issue 2. 1991-08-27. PMID:1713220. |
igfbp-1 may be another useful marker in evaluating the response of acromegaly to octreotide treatment in patients who experience clinical benefit but equivocal gh and igf-1 attenuation. |
1991-08-27 |
2023-08-11 |
Not clear |
| S Valdemarsson, M Bramnert, S Cronquist, A Elner, C M Eneroth, P Hedner, M Lindvall-Axelsson, C H Nordström, L G Strömbla. Early postoperative basal serum GH level and the GH response to TRH in relation to the long-term outcome of surgical treatment for acromegaly: a report on 39 patients. Journal of internal medicine. vol 230. issue 1. 1991-08-15. PMID:1906090. |
early postoperative basal serum gh level and the gh response to trh in relation to the long-term outcome of surgical treatment for acromegaly: a report on 39 patients. |
1991-08-15 |
2023-08-11 |
Not clear |
| S Valdemarsson, M Bramnert, S Cronquist, A Elner, C M Eneroth, P Hedner, M Lindvall-Axelsson, C H Nordström, L G Strömbla. Early postoperative basal serum GH level and the GH response to TRH in relation to the long-term outcome of surgical treatment for acromegaly: a report on 39 patients. Journal of internal medicine. vol 230. issue 1. 1991-08-15. PMID:1906090. |
it is concluded that the basal level of serum gh measured 1-7 d postoperatively has higher sensitivity and specificity than the gh response to trh 6-12 months postoperatively for evaluation of the effect of surgery on gh overproduction, and that it has a higher predictive power with regard to the long-term outcome of surgery for acromegaly. |
1991-08-15 |
2023-08-11 |
Not clear |
| P Bang, U Eriksson, V Sara, I L Wivall, K Hal. Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays: improvement of determinations in acid ethanol extracts by the use of truncated IGF-I as radioligand. Acta endocrinologica. vol 124. issue 6. 1991-08-15. PMID:2068892. |
with truncated igf-i as radioligand the igf-i measurements in acid gel filtrates and acid ethanol extracts were significantly correlated in healthy subjects (n = 42, r = 0.91, p less than 0.001) and in patients with acromegaly (n = 10, r = 0.85, p less than 0.01), gh deficiency (n = 10, r = 0.88, p less than 0.001) or type i diabetes mellitus (n = 10, r = 0.90, p less than 0.001). |
1991-08-15 |
2023-08-11 |
human |
| P Bang, U Eriksson, V Sara, I L Wivall, K Hal. Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays: improvement of determinations in acid ethanol extracts by the use of truncated IGF-I as radioligand. Acta endocrinologica. vol 124. issue 6. 1991-08-15. PMID:2068892. |
in contrast, the igf-i concentrations in acid ethanol extracts determined with igf-i as radioligand did not correlate with those in acid gel filtrates using truncated igf-i radioligand in patients with acromegaly (r = 0.61, ns) or gh deficiency (r = 0.46, ns). |
1991-08-15 |
2023-08-11 |
human |