| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Faglia, M Arosio, N Bazzon. Ectopic acromegaly. Endocrinology and metabolism clinics of North America. vol 21. issue 3. 1992-10-13. PMID:1521513. |
ectopic acromegaly is a rare syndrome (less than 1% of acromegalic patients) caused by ectopic growth hormone-releasing hormone (ghrh) or growth hormone (gh)-producing tumors. |
1992-10-13 |
2023-08-11 |
Not clear |
| G Faglia, M Arosio, N Bazzon. Ectopic acromegaly. Endocrinology and metabolism clinics of North America. vol 21. issue 3. 1992-10-13. PMID:1521513. |
patients with ghrh-induced acromegaly benefit from the administration of the long-acting somatostatin analog, octreotide, which reduces gh, igf-i, and ghrh, and may shrink the ectopic tumor, its metastases, and the secondary pituitary enlargement. |
1992-10-13 |
2023-08-11 |
Not clear |
| S A Lieberman, A G Björkengren, A R Hoffma. Rheumatologic and skeletal changes in acromegaly. Endocrinology and metabolism clinics of North America. vol 21. issue 3. 1992-10-13. PMID:1521515. |
the effects of chronic elevation of gh and igf-i levels on bony structures produce the typical physical changes associated with acromegaly, whereas the effects on cartilage result in arthropathy, which is usually degenerative. |
1992-10-13 |
2023-08-11 |
Not clear |
| S A Lieberman, A G Björkengren, A R Hoffma. Rheumatologic and skeletal changes in acromegaly. Endocrinology and metabolism clinics of North America. vol 21. issue 3. 1992-10-13. PMID:1521515. |
this article presents an overview of the physiologic roles of gh and igf-i in cartilage and bone metabolism, the clinical features of the degenerative arthropathy and other rheumatologic syndromes associated with acromegaly, effects of acromegaly on bone and mineral metabolism, and an unusual bone disease that is occasionally associated with acromegaly, the mccune-albright syndrome. |
1992-10-13 |
2023-08-11 |
Not clear |
| B M Chang-DeMoranville, I M Jackso. Diagnosis and endocrine testing in acromegaly. Endocrinology and metabolism clinics of North America. vol 21. issue 3. 1992-10-13. PMID:1521517. |
acromegaly is a characteristic clinical syndrome resulting from excessive production of gh and smc/igf-i generally from a gh-producing pituitary tumor. |
1992-10-13 |
2023-08-11 |
Not clear |
| P J Ho, R D Friberg, A L Barka. Regulation of pulsatile growth hormone secretion by fasting in normal subjects and patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 75. issue 3. 1992-10-08. PMID:1517371. |
in acromegaly, gh hypersecretion occurs despite elevated insulin-like growth factor-i (igf-i) levels, implying defective igf-i feedback. |
1992-10-08 |
2023-08-11 |
human |
| P J Ho, R D Friberg, A L Barka. Regulation of pulsatile growth hormone secretion by fasting in normal subjects and patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 75. issue 3. 1992-10-08. PMID:1517371. |
to study the possible mechanisms of defective igf-i negative feedback in acromegaly, we assessed parameters of pulsatile gh secretion during fasting-induced decrease in plasma igf-i. |
1992-10-08 |
2023-08-11 |
human |
| P J Ho, R D Friberg, A L Barka. Regulation of pulsatile growth hormone secretion by fasting in normal subjects and patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 75. issue 3. 1992-10-08. PMID:1517371. |
seven patients with active acromegaly and six normal controls were fasted for 6 days and gh secretory profiles were obtained by frequent (every 10 min) blood sampling for 24 h and analyzed by cluster. |
1992-10-08 |
2023-08-11 |
human |
| P J Ho, R D Friberg, A L Barka. Regulation of pulsatile growth hormone secretion by fasting in normal subjects and patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 75. issue 3. 1992-10-08. PMID:1517371. |
gh (and, by inference, ghrh) pulse frequency is resistant to decrease in igf-i in acromegaly, suggesting that lowered sensitivity of ghrh neurons to igf-i may be the mechanism of high gh pulse frequency in this disease. |
1992-10-08 |
2023-08-11 |
human |
| H Herlitz, O Jonsson, B A Bengtsso. Relationship between plasma growth hormone concentration and cellular sodium transport in acromegaly. Acta endocrinologica. vol 127. issue 1. 1992-10-08. PMID:1519421. |
we investigated the relationship between mean plasma growth hormone (gh) concentration and cellular sodium transport in untreated and treated acromegaly. |
1992-10-08 |
2023-08-11 |
Not clear |
| H Herlitz, O Jonsson, B A Bengtsso. Relationship between plasma growth hormone concentration and cellular sodium transport in acromegaly. Acta endocrinologica. vol 127. issue 1. 1992-10-08. PMID:1519421. |
seventeen patients (age 55 +/- 3 years) with active acromegaly were studied with respect to plasma gh (mean of 24 h gh profile) and erythrocyte electrolyte content as well as transmembrane sodium transport. |
1992-10-08 |
2023-08-11 |
Not clear |
| H Herlitz, O Jonsson, B A Bengtsso. Relationship between plasma growth hormone concentration and cellular sodium transport in acromegaly. Acta endocrinologica. vol 127. issue 1. 1992-10-08. PMID:1519421. |
in patients with active acromegaly there was a significant positive correlation between igf-1 and cellular sodium transport, while gh tended to show a negative relationship to the same parameter. |
1992-10-08 |
2023-08-11 |
Not clear |
| H Herlitz, O Jonsson, B A Bengtsso. Relationship between plasma growth hormone concentration and cellular sodium transport in acromegaly. Acta endocrinologica. vol 127. issue 1. 1992-10-08. PMID:1519421. |
in active acromegaly this may be counteracted by a sodium transport inhibitor giving the reverse relationship between gh and cellular sodium transport. |
1992-10-08 |
2023-08-11 |
Not clear |
| P J Ho, L M Fig, A L Barkan, B Shapir. Bone mineral density of the axial skeleton in acromegaly. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 33. issue 9. 1992-10-02. PMID:1517833. |
acromegaly is characterized by growth hormone (gh) hypersecretion and insulin-like growth factor-i (igf-i) excess, both of which stimulate osteoblast proliferation. |
1992-10-02 |
2023-08-11 |
Not clear |
| P J Ho, L M Fig, A L Barkan, B Shapir. Bone mineral density of the axial skeleton in acromegaly. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 33. issue 9. 1992-10-02. PMID:1517833. |
to investigate the effects of gh excess on proximal femur and lumbar spine bmd, a case series of 25 patients with acromegaly (8 eugonadal, 17 hypogonadal) documented by high plasma gh and igf-i concentrations was studied. |
1992-10-02 |
2023-08-11 |
Not clear |
| H Watanobe, M Ishii, T Kudo, A Nagata, K Takeb. A marked molecular heterogeneity of growth hormone (GH) detected in the plasma but not pituitary of a patient with acromegaly: comparison with other acromegalics and an implication for discrepant plasma levels of GH and insulin-like growth factor. Journal of endocrinological investigation. vol 15. issue 5. 1992-09-22. PMID:1506622. |
a marked molecular heterogeneity of growth hormone (gh) detected in the plasma but not pituitary of a patient with acromegaly: comparison with other acromegalics and an implication for discrepant plasma levels of gh and insulin-like growth factor. |
1992-09-22 |
2023-08-11 |
Not clear |
| A Utsumi, K Hanew, A Sugawara, Y Shimizu, O Murakami, H Ikeda, K Yoshinag. Plasma growth hormone (GH) responses to corticotropin-releasing hormone in patients with acromegaly--the effect of dexamethasone pretreatment and the comparison with GH responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and GH-releasing hormone. Journal of endocrinological investigation. vol 15. issue 3. 1992-08-11. PMID:1624675. |
plasma growth hormone (gh) responses to corticotropin-releasing hormone in patients with acromegaly--the effect of dexamethasone pretreatment and the comparison with gh responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and gh-releasing hormone. |
1992-08-11 |
2023-08-11 |
human |
| A Utsumi, K Hanew, A Sugawara, Y Shimizu, O Murakami, H Ikeda, K Yoshinag. Plasma growth hormone (GH) responses to corticotropin-releasing hormone in patients with acromegaly--the effect of dexamethasone pretreatment and the comparison with GH responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and GH-releasing hormone. Journal of endocrinological investigation. vol 15. issue 3. 1992-08-11. PMID:1624675. |
it has been reported that paradoxical gh responses to corticotropin-releasing hormone (crh) occur in only few patients with acromegaly. |
1992-08-11 |
2023-08-11 |
human |
| S L Asa, K Kovacs, E Horvath, W Singer, H S Smyt. Hormone secretion in vitro by plurihormonal pituitary adenomas of the acidophil cell line. The Journal of clinical endocrinology and metabolism. vol 75. issue 1. 1992-07-31. PMID:1352308. |
pituitary tumors producing gh and prl are morphologically classified as monomorphous bihormonal acidophil stem cell adenomas (ascas) which cause hyperprolactinemia and two tumor types which are usually associated with acromegaly, the monomorphous plurihormonal mammosomatotroph adenomas (msas) and bimorphous mixed somatotroph-lactotroph adenomas. |
1992-07-31 |
2023-08-11 |
Not clear |
| B Merola, A Colao, E Rossi, G La Tessa, R Spaziante, G Lombard. Hormonal gradients between inferior petrosal sinuses in various pituitary diseases. Acta endocrinologica. vol 126. issue 5. 1992-07-31. PMID:1621486. |
the aim of this retrospective study was to evaluate the existence of a multihormonal gradient between the inferior petrosal sinuses in various pituitary diseases: cushing's disease (8 cases), acromegaly (4 cases), prolactinomas (7 cases), gh, prl-secreting adenoma (1 case), functionless adenoma (2 cases), empty sella (3 cases) and in non-tumoral hyperprolactinemia (5 cases). |
1992-07-31 |
2023-08-11 |
Not clear |