Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Paul W Czoty, H Donald Gage, Susan H Nader, Beth A Reboussin, Michael Bounds, Michael A Nade. PET imaging of dopamine D2 receptor and transporter availability during acquisition of cocaine self-administration in rhesus monkeys. Journal of addiction medicine. vol 1. issue 1. 2013-06-06. PMID:21768930. |
previous studies have demonstrated that cocaine use alters availability of brain dopamine d2 receptors (d2r) and transporters (dat). |
2013-06-06 |
2023-08-12 |
monkey |
Gerda Thomsen, Gitte Moos Knudsen, Peter S Jensen, Morten Ziebell, Klaus K Holst, Susanne Asenbaum, Jan Booij, Jacques Darcourt, John C Dickson, Ozlem L Kapucu, Flavio Nobili, Osama Sabri, Terez Sera, Klaus Tatsch, Livia Tossici-Bolt, Koen Van Laere, Thierry Vander Borght, Andrea Varrone, Marco Pagani, Lars Hageman Pinbor. No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT. EJNMMI research. vol 3. issue 1. 2013-06-05. PMID:23688063. |
the dopamine transporter (dat) is of central importance in regulating dopaminergic neurotransmission and in particular in activating the striatal d2-like receptors. |
2013-06-05 |
2023-08-12 |
Not clear |
Elsmarieke van de Giessen, Swen Hesse, Matthan W A Caan, Franziska Zientek, John C Dickson, Livia Tossici-Bolt, Terez Sera, Susanne Asenbaum, Renaud Guignard, Umit O Akdemir, Gitte M Knudsen, Flavio Nobili, Marco Pagani, Thierry Vander Borght, Koen Van Laere, Andrea Varrone, Klaus Tatsch, Jan Booij, Osama Sabr. No association between striatal dopamine transporter binding and body mass index: a multi-center European study in healthy volunteers. NeuroImage. vol 64. 2013-06-04. PMID:22982354. |
striatal dopamine d(2) receptor availability is lower in obesity and there are indications that striatal dopamine transporter (dat) availability is also decreased. |
2013-06-04 |
2023-08-12 |
human |
Marco A T Utiumi, André C Felício, Conrado R Borges, Vera L Braatz, Sheyla A S Rezende, Renato P Munhoz, Rodrigo A Bressan, Henrique B Ferraz, Hélio A G Teiv. Dopamine transporter imaging in clinically unclear cases of parkinsonism and the importance of scans without evidence of dopaminergic deficit (SWEDDs). Arquivos de neuro-psiquiatria. vol 70. issue 9. 2013-06-04. PMID:22990721. |
recently, in vivo imaging techniques assessing the presynaptic dopamine transporter (dat) have emerged as a useful tool in pd diagnosis, improving its accuracy. |
2013-06-04 |
2023-08-12 |
Not clear |
D Enter, L S Colzato, K Roelof. Dopamine transporter polymorphisms affect social approach-avoidance tendencies. Genes, brain, and behavior. vol 11. issue 6. 2013-05-30. PMID:22494359. |
the 9-repeat allele of the dopamine transporter (dat) gene, associated with increased striatal dopamine levels, has been found to be related to increased sensitivity to reward. |
2013-05-30 |
2023-08-12 |
human |
Peiyan Wong, Cecilia Chin Roei Chang, Christine E Marx, Marc G Caron, William C Wetsel, Xiaodong Zhan. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. PloS one. vol 7. issue 12. 2013-05-30. PMID:23240026. |
here, we evaluate the actions of pregnenolone on a mouse model for schizophrenia, the dopamine transporter knockout mouse (dat ko). |
2013-05-30 |
2023-08-12 |
mouse |
Jun Zhu, Michael T Bardo, Linda P Dwoski. Distinct effects of enriched environment on dopamine clearance in nucleus accumbens shell and core following systemic nicotine administration. Synapse (New York, N.Y.). vol 67. issue 2. 2013-05-29. PMID:23065942. |
environmental enrichment during development may reduce drug abuse liability by modulating dopamine transporter (dat) function. |
2013-05-29 |
2023-08-12 |
rat |
Donald P Tashkin, Michael Rabinoff, Ernest P Noble, Terry L Ritchie, Michael S Simmons, John Connet. Association of dopamine-related gene alleles, smoking behavior and decline in FEV1 in subjects with COPD: findings from the lung health study. COPD. vol 9. issue 6. 2013-05-23. PMID:22958175. |
in post-hoc analyses, we assessed the association of the dopamine receptor (drd2) taqi a1(+) allele (a1a1, a1a2 genotypes) and a1(-) allele (a2a2 genotype), and the dopamine transporter (dat) 9r(+) allele (9r9r and 9r10r genotypes) and 9r(-) allele (10r10r genotype) with both changes in smoking status and lung function in a subset of lhs subjects. |
2013-05-23 |
2023-08-12 |
human |
Jianjun Sun, Jinbin Xu, Nigel J Cairns, Joel S Perlmutter, Robert H Mac. Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. PloS one. vol 7. issue 11. 2013-05-22. PMID:23185343. |
dopamine d1, d2, d3 receptors, vesicular monoamine transporter type-2 (vmat2) and dopamine transporter (dat) densities in aged human brain. |
2013-05-22 |
2023-08-12 |
human |
Jianjun Sun, Jinbin Xu, Nigel J Cairns, Joel S Perlmutter, Robert H Mac. Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. PloS one. vol 7. issue 11. 2013-05-22. PMID:23185343. |
the dopamine d(1), d(2), d(3) receptors, vesicular monoamine transporter type-2 (vmat2), and dopamine transporter (dat) densities were measured in 11 aged human brains (aged 77-107.8, mean: 91 years) by quantitative autoradiography. |
2013-05-22 |
2023-08-12 |
human |
José Luiz Pedroso, Pedro Braga-Neto, André C Felício, Thais Minett, Elton Yamaguchi, Lucila Bizari Fernandes do Prado, Luciane Bizari C Carvalho, Lívia Almeida Dutra, Marcelo Queiroz Hoexter, Antônio José da Rocha, Rodrigo A Bressan, Gilmar Fernandes do Prado, Orlando Graziani Povoas Barsottin. Sleep disorders in Machado-Joseph disease: a dopamine transporter imaging study. Journal of the neurological sciences. vol 324. issue 1-2. 2013-05-21. PMID:23137414. |
this study assessed the relationship between sleep disorders in mjd and dopamine transporter (dat) densities. |
2013-05-21 |
2023-08-12 |
Not clear |
Jürgen Innos, Este Leidmaa, Mari-Anne Philips, Silva Sütt, Aet Alttoa, Jaanus Harro, Sulev Kõks, Eero Vasa. Lsamp⁻/⁻ mice display lower sensitivity to amphetamine and have elevated 5-HT turnover. Biochemical and biophysical research communications. vol 430. issue 1. 2013-05-14. PMID:23206697. |
finally, lsamp(-/-) mice had lower level of dopamine transporter (dat) mrna in the mesencephalon. |
2013-05-14 |
2023-08-12 |
mouse |
Eunkyung Par. A new era of clinical dopamine transporter imaging using 123I-FP-CIT. Journal of nuclear medicine technology. vol 40. issue 4. 2013-05-13. PMID:23160562. |
(123)i-fp-cit is a radioligand for brain dopamine transporter (dat) imaging that is useful for the differential diagnosis of parkinson disease (pd) and other diseases that mimic pd. |
2013-05-13 |
2023-08-12 |
Not clear |
Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Dina M Francescutti, Catherine E Sykes, Mrudang M Shah, David M Thomas, Donald M Kuh. Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA. Journal of neurochemistry. vol 125. issue 1. 2013-05-13. PMID:23205838. |
one of the most powerful actions associated with mephedrone is the ability to stimulate dopamine (da) release and block its re-uptake through its interaction with the dopamine transporter (dat). |
2013-05-13 |
2023-08-12 |
mouse |
Daniela Di Giuda, Giovanni Camardese, Anna Rita Bentivoglio, Fabrizio Cocciolillo, Arianna Guidubaldi, Lorella Pucci, Isabella Bruno, Luigi Janiri, Alessandro Giordano, Alfonso Fasan. Dopaminergic dysfunction and psychiatric symptoms in movement disorders: a 123I-FP-CIT SPECT study. European journal of nuclear medicine and molecular imaging. vol 39. issue 12. 2013-05-07. PMID:22976499. |
we assessed dopamine transporter (dat) availability by means of (123)i-fp-cit spect, and motor and psychiatric features in patients with parkinson's disease, primary dystonia and essential tremor, exploring the association between spect findings and symptom severity. |
2013-05-07 |
2023-08-12 |
Not clear |
Norihiro Harada, Hiroyuki Ohba, Takeharu Kakiuchi, Hideo Tsukad. Application of feedback-controlled bolus plus infusion (FC-B/I) method for quantitative PET imaging of dopamine transporters with [(18)F]β-CFT-FE in conscious monkey brain. Synapse (New York, N.Y.). vol 67. issue 1. 2013-05-07. PMID:23042662. |
the competitive inhibition of dopamine transporters (dat) with cocaine, a specific dat inhibitor, was evaluated with a feedback-controlled bolus plus infusion (fc-b/i) method using animal positron emission tomography (pet) in the living brain of conscious monkey. |
2013-05-07 |
2023-08-12 |
monkey |
Joong-Seok Kim, Yoon-Sang Oh, Yeong-In Kim, Dong-Won Yang, Yong-An Chung, Ie-Ryung You, Kwang-Soo Le. Combined use of ¹²³I-metaiodobenzylguanidine (MIBG) scintigraphy and dopamine transporter (DAT) positron emission tomography (PET) predicts prognosis in drug-induced Parkinsonism (DIP): a 2-year follow-up study. Archives of gerontology and geriatrics. vol 56. issue 1. 2013-05-03. PMID:22633343. |
combined use of ¹²³i-metaiodobenzylguanidine (mibg) scintigraphy and dopamine transporter (dat) positron emission tomography (pet) predicts prognosis in drug-induced parkinsonism (dip): a 2-year follow-up study. |
2013-05-03 |
2023-08-12 |
Not clear |
P Rojas, E Ruiz-Sánchez, C Rojas, S O Ogre. Ginkgo biloba extract (EGb 761) modulates the expression of dopamine-related genes in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. Neuroscience. vol 223. 2013-05-01. PMID:22885234. |
the genes for tyrosine hydroxylase (th), vesicular monoamine transporter 2 (vmat2), dopamine transporter (dat), dopamine d2 receptor (da-d2r), and transcription factors (pitx3 and nurr1) related to dopamine neurotransmission were selected for the analysis. |
2013-05-01 |
2023-08-12 |
mouse |
Bonnie A Merchant, Jeffry D Madur. Insights from molecular dynamics: the binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters. Journal of molecular graphics & modelling. vol 38. 2013-04-30. PMID:23079638. |
the dopamine transporter (dat) facilitates the regulation of synaptic neurotransmitter levels. |
2013-04-30 |
2023-08-12 |
Not clear |
Bonnie A Merchant, Jeffry D Madur. Insights from molecular dynamics: the binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters. Journal of molecular graphics & modelling. vol 38. 2013-04-30. PMID:23079638. |
a comparison of free energy profiles for dopamine and cocaine in dat suggests that the binding site of cocaine is located in a secondary pocket, not the primary substrate site. |
2013-04-30 |
2023-08-12 |
Not clear |