| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shining Deng, Lingli Zhang, Tailin Zhu, Yan-Mei Liu, Hailong Zhang, Yiping Shen, Wei-Guang Li, Fei L. A behavioral defect of temporal association memory in mice that partly lack dopamine reuptake transporter. Scientific reports. vol 5. 2016-10-13. PMID:26658842. |
we used hemizygote hyperdopaminergic mutant mice with reduced dopamine transporter (dat) expression, referred to as dat(+/-) mice. |
2016-10-13 |
2023-08-13 |
mouse |
| Ajinkya Sase, Yogesh D Aher, Sivaprakasam R Saroja, Minu Karthika Ganesan, Sunetra Sase, Marion Holy, Harald Höger, Vasiliy Bakulev, Gerhard F Ecker, Thierry Langer, Harald H Sitte, Johann Leban, Gert Lube. A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes. Neuropharmacology. vol 102. 2016-10-07. PMID:26407764. |
binding of ce-103 to the dopamine (dat), serotonin (sert) and norepinephrine (net) transporters and dopamine reuptake inhibition was tested as well as blood brain permeation and a screen for gpcr targets. |
2016-10-07 |
2023-08-13 |
rat |
| Ajinkya Sase, Yogesh D Aher, Sivaprakasam R Saroja, Minu Karthika Ganesan, Sunetra Sase, Marion Holy, Harald Höger, Vasiliy Bakulev, Gerhard F Ecker, Thierry Langer, Harald H Sitte, Johann Leban, Gert Lube. A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes. Neuropharmacology. vol 102. 2016-10-07. PMID:26407764. |
hippocampi were taken 6 h following the last day of training and complexes containing the unphosphorylated or phosphorylated dopamine transporter (dat) and complexes containing the d1-3 dopamine receptor subunits were determined. |
2016-10-07 |
2023-08-13 |
rat |
| Ajinkya Sase, Yogesh D Aher, Sivaprakasam R Saroja, Minu Karthika Ganesan, Sunetra Sase, Marion Holy, Harald Höger, Vasiliy Bakulev, Gerhard F Ecker, Thierry Langer, Harald H Sitte, Johann Leban, Gert Lube. A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes. Neuropharmacology. vol 102. 2016-10-07. PMID:26407764. |
ce-103 was binding to the dat but insignificantly to sert or net and dopamine reuptake was blocked specifically (ic50 = 14.73 μm). |
2016-10-07 |
2023-08-13 |
rat |
| Jordan T Yorgason, Erin S Calipari, Mark J Ferris, Anushree N Karkhanis, Steven C Fordahl, Jeffrey L Weiner, Sara R Jone. Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum. Neuropharmacology. vol 101. 2016-10-05. PMID:26525189. |
in regard to psychostimulant effects directly at the dopamine transporter (dat), methylphenidate and amphetamine, but not cocaine, inhibited uptake more in si than gh rats. |
2016-10-05 |
2023-08-13 |
rat |
| Jordan T Yorgason, Erin S Calipari, Mark J Ferris, Anushree N Karkhanis, Steven C Fordahl, Jeffrey L Weiner, Sara R Jone. Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum. Neuropharmacology. vol 101. 2016-10-05. PMID:26525189. |
cocaine's effects on uptake were similar between rearing conditions, however, cocaine enhanced evoked dopamine release greater in si than gh rats, suggesting that the enhanced cocaine reinforcement in si animals involves a dat independent mechanism. |
2016-10-05 |
2023-08-13 |
rat |
| J R Yates, M Darna, J S Beckmann, L P Dwoskin, M T Bard. Individual differences in impulsive action and dopamine transporter function in rat orbitofrontal cortex. Neuroscience. vol 313. 2016-09-30. PMID:26608122. |
although previous research has shown that dopamine (da) systems in prefrontal cortex are involved in impulsivity and substance abuse, it is not known if inherent variation in da transporter (dat) function contributes to impulsivity. |
2016-09-30 |
2023-08-13 |
rat |
| Susanne Pirker, Laura Perju-Dumbrava, Gabor G Kovacs, Tatiana Traub-Weidinger, Walter Pirke. Progressive Dopamine Transporter Binding Loss in Autopsy-Confirmed Corticobasal Degeneration. Journal of Parkinson's disease. vol 5. issue 4. 2016-09-29. PMID:26485425. |
recent single photon emission tomography (spect) studies have reported normal striatal dopamine transporter (dat) binding in individual patients with cbd. |
2016-09-29 |
2023-08-13 |
Not clear |
| Subramanian Mariappan, Wieslaw Bogdanowicz, Hanumanthan Raghuram, Ganapathy Marimuthu, Koilmani Emmanuvel Raja. Structure of distress call: implication for specificity and activation of dopaminergic system. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 202. issue 1. 2016-09-27. PMID:26610332. |
we subsequently found that tyrosine hydroxylase (th) and its transcription factor-nuclear receptor related factor 1 (nurr-1); and the dopamine transporter (dat) and its receptor (d1dr) were elevated significantly in the amygdala of bats both emitting and responding to a distress call, but not in the case of bats responding to the modified call. |
2016-09-27 |
2023-08-13 |
Not clear |
| Soichiro Shimizu, Kentaro Hirao, Hidekazu Kanetaka, Nayuta Namioka, Hirokuni Hatanaka, Daisuke Hirose, Raita Fukasawa, Takahiko Umahara, Hirohumi Sakurai, Haruo Hany. Utility of the combination of DAT SPECT and MIBG myocardial scintigraphy in differentiating dementia with Lewy bodies from Alzheimer's disease. European journal of nuclear medicine and molecular imaging. vol 43. issue 1. 2016-09-26. PMID:26233438. |
(123)i-2β-carbomethoxy-3β-(4-iodophenyl)-n-(3-fluoropropyl) nortropane ((123)i-fp-cit) dopamine transporter single photon emission computed tomography (dat spect) and (123)i-metaiodobenzylguanidine (mibg) myocardial scintigraphy can be used to assist in the diagnosis of patients with dementia with lewy bodies (dlb). |
2016-09-26 |
2023-08-13 |
Not clear |
| Julie A Marusich, Kateland R Antonazzo, Bruce E Blough, Simon D Brandt, Pierce V Kavanagh, John S Partilla, Michael H Bauman. The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue. Neuropharmacology. vol 101. 2016-09-22. PMID:26362361. |
here, the monoamine-releasing properties of 5-it, its structural isomer 6-(2-aminopropyl)indole (6-it), and mdma were compared using in vitro release assays at transporters for dopamine (dat), norepinephrine (net), and serotonin (sert) in rat brain synaptosomes. |
2016-09-22 |
2023-08-13 |
mouse |
| Friederike Matthaeus, Patrick Schloss, Thorsten La. Differential Uptake Mechanisms of Fluorescent Substrates into Stem-Cell-Derived Serotonergic Neurons. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26503837. |
the actions of the neurotransmitters serotonin, dopamine, and norepinephrine are partly terminated by diffusion and in part by their uptake into neurons via the selective, high-affinity transporters for serotonin (sert), dopamine (dat), and norepinephrine (net), respectively. |
2016-09-21 |
2023-08-13 |
Not clear |
| David K Grandy, Gregory M Miller, Jun-Xu L. "TAARgeting Addiction"--The Alamo Bears Witness to Another Revolution: An Overview of the Plenary Symposium of the 2015 Behavior, Biology and Chemistry Conference. Drug and alcohol dependence. vol 159. 2016-09-19. PMID:26644139. |
and whether aware of the coincidence or not, those in attendance witnessed the plunging of the metaphorical dagger into the heart of the dopamine (da) transporter (dat)-centric view of psychostimulant action. |
2016-09-19 |
2023-08-13 |
Not clear |
| Christina D'Arcy, Joe E Luevano, Manuel Miranda-Arango, Joseph A Pipkin, Jonathan A Jackson, Eddie Castañeda, Kristin L Gosselink, Laura E O'Del. Extended access to methamphetamine self-administration up-regulates dopamine transporter levels 72 hours after withdrawal in rats. Behavioural brain research. vol 296. 2016-09-15. PMID:26367473. |
this study examined changes in striatal dopamine transporter (dat), tyrosine hydroxylase (th) and dopamine receptor 2 (d2) 72 h after withdrawal from meth intravenous self- administration (ivsa). |
2016-09-15 |
2023-08-13 |
rat |
| Jacob Andersen, Kristoffer B Ringsted, Benny Bang-Andersen, Kristian Strømgaard, Anders S Kristense. Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter. Scientific reports. vol 5. 2016-09-15. PMID:26503701. |
the transporters for norepinephrine and dopamine (net and dat, respectively) constitute the molecular targets for recreational drugs and therapeutics used in the treatment of psychiatric disorders. |
2016-09-15 |
2023-08-13 |
human |
| Julieta E Arena, A Jon Stoess. Optimizing diagnosis in Parkinson's disease: Radionuclide imaging. Parkinsonism & related disorders. vol 22 Suppl 1. 2016-09-12. PMID:26439947. |
presynaptic dopaminergic dysfunction in pd can be revealed through the imaging of different steps in the process of dopamine synthesis and storage: l-aromatic amino acid decarboxylase (aadc) activity, vesicular monoamine transporter type 2 (vmat2) binding or its reuptake via the dopamine transporter (dat). |
2016-09-12 |
2023-08-13 |
Not clear |
| Shu-Ying Liu, Jian-Jun Wu, Jue Zhao, Si-Fei Huang, Yi-Xuan Wang, Jing-Jie Ge, Ping Wu, Chuan-Tao Zuo, Zheng-Tong Ding, Jian Wan. Onset-related subtypes of Parkinson's disease differ in the patterns of striatal dopaminergic dysfunction: A positron emission tomography study. Parkinsonism & related disorders. vol 21. issue 12. 2016-09-12. PMID:26559130. |
this study investigated whether the two subtypes differ in the pattern of dysfunction in striatal (caudate and putamen) dopaminergic system and if the dopamine transporter (dat) imaging patterns are associated with the clinical features of corresponding pd subtype. |
2016-09-12 |
2023-08-13 |
Not clear |
| Irina Baetu, Nicholas R Burns, Kristi Urry, Girolamo Giovanni Barbante, Julia B Pitche. Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26419600. |
in particular, we investigated variations in genes that code for the catechol-o-methyltransferase (comt) enzyme, the dopamine transporter (dat) and dopamine d1 and d2 receptors (drd1 and drd2). |
2016-09-09 |
2023-08-13 |
human |
| Irina Baetu, Nicholas R Burns, Kristi Urry, Girolamo Giovanni Barbante, Julia B Pitche. Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26419600. |
comt and the dat regulate dopamine availability in the prefrontal cortex and the striatum, respectively, two key regions recruited during learning, whereas dopamine d1 and d2 receptors are thought to be involved in long-term potentiation and depression, respectively. |
2016-09-09 |
2023-08-13 |
human |
| Ioannis U Isaias, Paula Trujillo, Paul Summers, Giorgio Marotta, Luca Mainardi, Gianni Pezzoli, Luigi Zecca, Antonella Cost. Neuromelanin Imaging and Dopaminergic Loss in Parkinson's Disease. Frontiers in aging neuroscience. vol 8. 2016-09-06. PMID:27597825. |
striatal dopaminergic innervation was measured as density of dopamine transporter (dat) by means of single-photon emission computed tomography and [(123)i] n-ω-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl) tropane. |
2016-09-06 |
2023-08-13 |
human |