| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicodemus Emeka Nwankwo, Emmanuel Henry Ezenabor, Obiora Emmanuel Abonyi, Bartholomew Onyekachi Okol. Antiplasmodial Potentials, Phytocompounds, and the Possible Toxic Effects of Administration of Ethylacetate Extract of Spondias mombin Linn. Chemistry & biodiversity. 2025-01-17. PMID:39629680. |
liver function tests showed mixed effects, with elevated aspartate aminotransferase (ast), alkaline phosphatase (alp), and total bilirubin (tb) levels at some doses, yet decreased alanine aminotransferase (alt) at the highest dose, suggesting possible hepatoprotective effects. |
2025-01-17 |
2025-01-20 |
mouse |
| Liangyu Zhang, Leilei Gu, Hongqun Qia. 26-Week Repeated-Dose Toxicity Study of a Novel Antiarrhythmic Drug Sulcardine Sulfate in Sprague-Dawley Rats. Journal of applied toxicology : JAT. 2025-01-17. PMID:39821320. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in male rats significantly increased in the medium- and high-dose groups, whereas female rats in these groups showed a significant rise in alkaline phosphatase (alp) levels, accompanied by varying degrees of weight gain in the liver and lungs. |
2025-01-17 |
2025-01-20 |
rat |
| Shuhua Ai, Juanli Pan, Qi Liu, Fenfen Tang, Ting Wen, Yulin Yuan, Qunjun He, Lu Huan. OTUB1 mediates PARP1 deubiquitination to alleviate NAFLD by regulating HMGB1. Experimental cell research. 2025-01-15. PMID:39814124. |
the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) were assessed using the corresponding biochemical assays. |
2025-01-15 |
2025-01-19 |
mouse |
| Xinhui Zhang, Fengyan Zhang, Musen Li, Qingsong Sun, Yuehong Li, Yunhe Fu, Yue Zhan. Epicatechin attenuates emamectin benzoate-induced liver injury in grass carp by activating Nrf2/GPX4 signaling pathway. Fish & shellfish immunology. 2025-01-14. PMID:39809417. |
the results provide direct evidence that epicatechin could attenuate emb-induced liver injury, as confirmed by the inhibition of epicatechin on emb-induced liver pathological injury, serum glucose (glu), cortisol (cor), aspartate aminotransferase (ast), alanine aminotransferase (alt), adenosine deaminase (ada), and alkaline phosphatase (alp) levels. |
2025-01-14 |
2025-01-17 |
Not clear |
| Samar M Mohamed, Mahmoud Alagawany, Mohamed S El-Kholy, Mohamed M El-Mekkawy, Ayman S Salah, Youssef A Attia, Rashed A Alhotan, Alessandro Di Cerbo, Antonia Lesting. Effect of dietary microalgae on growth performance and health in meat-type quails. Poultry science. vol 104. issue 2. 2025-01-13. PMID:39805252. |
the dsap1 group significantly (p=0.003) presented the lowest level of alanine aminotransferase (alt) and the dsap2 group significantly (p<0.001) presented the lowest levels of aspartate aminotransferase (ast) and urea. |
2025-01-13 |
2025-01-16 |
Not clear |
| Meng Fang, Dong-Rui Huang, Jin-Wei Zhang, Wen-Jing Liao, Fang Wu, Yu-Wei Li. [Tanshinone Ⅱ_A exerts anti-hepatocellular carcinoma effects by inhibiting oxidative stress via PI3K/Akt and Nrf2/HO-1 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 24. 2025-01-13. PMID:39805761. |
hematoxylin-eosin(he) staining was used to observe the pathological changes in the liver tissue, and an automatic biochemical analyzer was used to measure the levels of alanine aminotransferase(alt) and aspartate aminotransferase(ast) in the mice serum. |
2025-01-13 |
2025-01-16 |
mouse |
| Shuqin Lin, Yunjuan Xiao, Siyu Li, Liyan Tang, Haitao Shi, Meiling Hong, Li Din. Thiacloprid exposure disrupts the gut-liver axis and induces liver dysfunction in the Reeves' turtles (Mauremys reevesii). Ecotoxicology and environmental safety. vol 289. 2025-01-12. PMID:39799922. |
furthermore, elevated levels of liver function indicators, including aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), total bile acid (tba), and triglyceride (tg), were positively correlated with increased thi concentrations. |
2025-01-12 |
2025-01-16 |
Not clear |
| Jinliang Liang, Huanyi Liu, Guo Lv, Xiaotong Chen, Zhaoshou Yang, Kunhua Hu, Hongyan Su. Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics. Lipids in health and disease. vol 24. issue 1. 2025-01-11. PMID:39794823. |
the results demonstrated that tirzepatide significantly reduced serum levels of alanine transaminase (alt) and aspartate transaminase (ast), as well as hepatic triglycerides (tg) and total cholesterol (tc), indicating its efficacy in treating mafld. |
2025-01-11 |
2025-01-14 |
mouse |
| Mohamed N Monier, Asmaa S Abd El-Naby, Reham M Fawzy, Fatma Samir, Sherien H H Shady, Youssif Shehata Grana, Najah M Albaqami, Mohsen Abdel-Tawwa. Growth performance, antioxidant, and immune responses of Nile tilapia (Oreochromis niloticus) fed on low-fishmeal diets enriched with sodium chloride and its adaptability to different salinity levels. Fish physiology and biochemistry. vol 51. issue 1. 2025-01-10. PMID:39789358. |
on the other hand, feeding fish on a diet containing 10 g nacl/kg feed showed substantially lower levels of cortisol, glucose, cholesterol, triglycerides, aspartate transaminase (ast), alanine transaminase (alt), and malondialdehyde (mda). |
2025-01-10 |
2025-01-13 |
Not clear |
| Nagat M Aly, Anter K Mahmoud, Eman M Mosalla. Biochemical targets of chick embryos affected by sub-lethal concentrations of lambda-cyhalothrin and imidacloprid. Research in veterinary science. vol 184. 2025-01-10. PMID:39793169. |
there were significant changes (reduction or enhancement) in serum activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt) by lct and imd at the used concentrations, while non-significant stimulation in the ast/alt ratio (aar) was found. |
2025-01-10 |
2025-01-14 |
chicken |
| Hai-Ying Tian, Dao-Jiang Yu, Teng Xie, Meng-Xia Xu, Yu-Hao Wang, Xi-Lu Sun, Xin-Meng Zhou, Ying-Xuan Han, Qing-Qing Liao, Yu-Jie Zhao, Juan Liao, Mohamed El-Kassas, Xiao-Dong Sun, Yuan-Yuan Zhan. Cordycepin alleviates metabolic dysfunction-associated liver disease by restoring mitochondrial homeostasis and reducing oxidative stress via Parkin-mediated mitophagy. Biochemical pharmacology. 2025-01-10. PMID:39793718. |
serum total cholesterol (tc), triacylglyceride (tg), and aspartate aminotransferase (ast) levels were measured. |
2025-01-10 |
2025-01-14 |
mouse |
| Hugo Giordano Tavares, Patrícia Ribeiro Orlando, Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz E Magalhães, Gabriela Silva, Alice Dos Santos Nunes Ferreira, Bruna Caroline Chaves Garcia, Karen Rodrigues Lima, Etel Rocha Vieira, Leonardo Barros Dobbss, Marco Fabrício Dias-Peixoto, Alan Rodrigues Teixeira Machado, Luciano José Pereira, Eric Francelino Andrad. Humic acid from vermicompost effectively regulates the redox status and mitigates the progression of experimental periodontitis. Naunyn-Schmiedeberg's archives of pharmacology. 2025-01-10. PMID:39792165. |
after euthanasia, alveolar bone loss, oxidative stress in the gum and erythrocytes, serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and creatinine were analyzed. |
2025-01-10 |
2025-01-13 |
rat |
| Ewelina Bogdańska-Chomczyk, Paweł Wojtacha, Meng-Li Tsai, Andrew Chih Wei Huang, Anna Kozłowsk. Alterations in Striatal Architecture and Biochemical Markers' Levels During Postnatal Development in the Rat Model of an Attention Deficit/Hyperactivity Disorder (ADHD). International journal of molecular sciences. vol 25. issue 24. 2025-01-08. PMID:39769412. |
alanine transaminase (alt), and aspartate transaminase (ast). |
2025-01-08 |
2025-01-13 |
rat |
| Daryna Mruga, Kseniia Berketa, Andrii Sverstiuk, Vasyl Martsenyuk, Aleksandra Klos-Witkowska, Yurii Palianytsia, Sergei Dzyadevych, Oleksandr Soldatki. Amperometric Biosensor Based on Glutamate Oxidase to Determine Ast Activity. Sensors (Basel, Switzerland). vol 24. issue 24. 2025-01-08. PMID:39771630. |
this work presents the development of an amperometric biosensor for detecting aspartate aminotransferase (ast) activity in biological fluids using a platinum disk electrode as the working transducer. |
2025-01-08 |
2025-02-24 |
Not clear |
| Leah K Manning, Katie L M Eager, Cali E Willet, Shaun Slattery, Justine H McNally, Zoe B Spiers, Mark Hazelton, Georgina Child, Rick Duggan, Brendon A O'Rourke, Imke Tamme. Myotonia Congenita in Australian Merino Sheep with a Missense Variant in Animals : an open access journal from MDPI. vol 14. issue 24. 2025-01-08. PMID:39765607. |
biochemistry from four sheep found variable, but typically mild increases in creatine kinase (ck) and aspartate aminotransferase (ast). |
2025-01-08 |
2025-01-13 |
Not clear |
| Arsalan Seyedi, Soghra Rabizadeh, Sahar Karimpour Reyhan, Sara Hobaby, Samira Amin Afshari, Mostafa Shomalzadeh, Seyed Ali Nabipoorashrafi, Nasrin Asgari Soran, Amirhossein Yadegar, Fatemeh Mohammadi, Fatemeh Moosaei, Elahe Saffari, Sajedeh Riazi, Fatemeh Sarv, Manouchehr Nakhjavani, Abdolreza Pazouki, Alireza Esteghamat. Impact of bariatric surgery on liver fibrosis indices among type 2 diabetes patients in a national cohort. Scientific reports. vol 15. issue 1. 2025-01-08. PMID:39775004. |
these liver indices were fibrosis-4 (fib-4) index, aspartate aminotransferase (ast) to platelet ratio index, and non-alcoholic fatty liver disease (nafld) fibrosis score. |
2025-01-08 |
2025-01-13 |
Not clear |
| Trishnarani Jena, Suraj Kumar Chhatoi, Swati Saurabini Khandai, Rutusmita Mishra, Abhipsa Mohanty, Kisan Kumar Sharma, Surjyasikha Samal, Kewal Kumar Mahapatra, Gyanaseni Dhar, Swetashree Purohit, Debasish Mohapatr. Sublethal Urea Exposure in Nile Tilapia: Morphological, Behavioural, and Histological Alteration. Chemosphere. 2025-01-08. PMID:39778661. |
significant rises in the enzymatic activity such as alanine aminotransferase (alt), alkaline phosphatase (alp), and aspartate aminotransferase (ast) upon urea treatment emphasize the possibilities of liver damage, biliary obstruction, and abnormal glucose metabolism. |
2025-01-08 |
2025-01-13 |
Not clear |
| Fares A Eldeeb, Enas A Noseer, Shimaa Abdelazeem, Esraa Ali, Asmaa W Basher, M A A Abdalla, Hytham H Ibrahi. Effect of dietary supplementation of Lawsonia inermis and Acacia nilotica extract on growth performance, intestinal histopathology, and antioxidant status of broiler chickens challenged with coccidiosis. BMC veterinary research. vol 21. issue 1. 2025-01-07. PMID:39762829. |
all challenged broilers had higher aspartate aminotransferase (ast), alanine transaminase (alt), urea, creatinine, glucose, mda, il-4 &tnf-α levels compared to all unchallenged broilers. |
2025-01-07 |
2025-01-13 |
Not clear |
| Fatih Günaydın, Öner Kılınç, Bülent Sakarya, İdris Demirtaş, Mahmud Aydın, Ali Çeli. AST/ALT ratio as a potential predictor of 1-year mortality in elderly patients operated for femoral neck fracture. BMC musculoskeletal disorders. vol 26. issue 1. 2025-01-07. PMID:39762836. |
elevated aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels, as well as the ast/alt ratio (aar), have been associated with mortality in various diseases, but their association with hip fracture mortality remains underexplored. |
2025-01-07 |
2025-01-13 |
Not clear |
| Mohammed Yasser Hussein, Merna Nasr, Veronia Emad, Julie Maged, Portia George, Amina Emad, Abeer Mahmoud Badr, Mehrez E El-Naggar, Sayeda M Abdo, Jihan Hussei. Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies. Scientific reports. vol 15. issue 1. 2025-01-06. PMID:39762303. |
smne also demonstrated efficacy in inhibiting tumor growth in mice with ehrlich ascites carcinoma, normalizing alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, and reducing oxidative stress markers such as catalase (cat) and malondialdehyde (mda). |
2025-01-06 |
2025-01-13 |
mouse |