| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Li, Fengyue Zhu, Lili Dai, Christer Hogstrand, Boqun Li, Xikai Yue, Jianghua Wang, Liqin Yu, Dapeng L. Effects of 2-ethylhexyl diphenyl phosphate (EHDPP) on glycolipid metabolism in male adult zebrafish revealed by targeted lipidomic analyses. The Science of the total environment. 2024-06-27. PMID:38936724. |
results indicated significant liver damages in the 100 and 250 μg/l ehdpp groups, which both exhibited significant decreases in hepatic somatic index (hsi), elevated activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in serum and liver, as well as hepatocyte vacuolation and nuclear pyknosis. |
2024-06-27 |
2024-06-30 |
zebrafish |
| Abdulaziz Qaid Ali, Deema Kamal Sabir, Amal F Dawood, Mohammed Abu-Rashed, Abdulrahman Hasari, Faiz Gharqan, Salem Alnefaie, Lama E Mohiddin, Maya M Tatry, Dana A Albadan, Mohanad M Alyami, Mohammed F Almutairi, Lamiaa M Shawk. The potential liver injury induced by metronidazole-provoked disturbance of gut microbiota: modulatory effect of turmeric supplementation. Naunyn-Schmiedeberg's archives of pharmacology. 2024-06-26. PMID:38922353. |
the liver enzymes (aminotransferase (alt) and aspartate aminotransferase (ast)) and histopathological examination were estimated to assess liver function. |
2024-06-26 |
2024-06-29 |
rat |
| Hussein Awad Hussein, Amany M Mohammed Omer, Mohammad H Kara. Variations of blood metabolites in single- and multiple-bearing Ossimi ewes during the transition period. Reproduction in domestic animals = Zuchthygiene. vol 59. issue 6. 2024-06-26. PMID:38924155. |
the serum activities of aspartate aminotransferase (ast) and gamma-glutamyltransferase (ggt) were significantly increased at 1-week after parturition in both groups (p < .05). |
2024-06-26 |
2024-06-29 |
Not clear |
| Qing-Xiang Zheng, Qing-Lin Liu, Wen-Na Sun, Xin-Yu Jiang, Tao Zen. Biphasic effects of ethanol consumption on N,N-dimethylformamide-induced liver injury in mice. Toxicology. vol 506. 2024-06-26. PMID:38924947. |
we found that a single dose of ethanol (1.25, 2.5, or 5 g/kg bw by gavage) significantly repressed the increase in serum alanine transaminase (alt) and aspartate transaminase (ast) activities and alleviated the liver histopathological changes in mice challenged with 3 g/kg dmf. |
2024-06-26 |
2024-06-29 |
mouse |
| Yinxing Zhu, Min Jiang, Zihan Gu, Hongyu Shang, Caiyin Tang, Ting Gu. Elucidating the role of liver enzymes as markers and regulators in ovarian cancer: a synergistic approach using Mendelian randomization, single-cell analysis, and clinical evidence. Human genomics. vol 18. issue 1. 2024-06-25. PMID:38915066. |
methods genome-wide association studies for oc and levels of enzymes such as alkaline phosphatase (alp), aspartate aminotransferase (ast), alanine aminotransferase, and gamma-glutamyltransferase were analyzed. |
2024-06-25 |
2024-06-27 |
human |
| Mohamed M Mabrouk, Mohamed Ashour, Elsayed M Younis, Abdel-Wahab A Abdel-Warith, Mohamed A Bauomi, Mohamed M Toutou, Ahmed I A Mansour, Basem S Abdelaty, Mohamed A Elokaby, Simon J Davies, Ehab El-Haroun, Ahmed G A Gwid. Arthrospira platensis nanoparticles dietary supplementation improves growth performance, steroid hormone balance, and reproductive productivity of Nile tilapia (Oreochromis niloticus) broodstock. PloS one. vol 19. issue 6. 2024-06-25. PMID:38917116. |
compared to the an0 group, fish fed on the supplemented diets showed significant improvement (p < 0.05) in triglyceride, glucose, and aspartate aminotransferase (ast). |
2024-06-25 |
2024-06-29 |
Not clear |
| Rebecca L Koch, James B Stanton, Susan McClatchy, Gary A Churchill, Steven W Craig, Darian N Williams, Mallory E Johns, Kylah R Chase, Dana L Thiesfeldt, Jessica C Flynt, Robert Pazdr. Discovery of genomic loci for liver health and steatosis reveals overlap with glutathione redox genetics. Redox biology. vol 75. 2024-06-25. PMID:38917671. |
to better understand the relationship between the glutathione redox system and signs of nafld in a genetically-diverse population, we measured liver weight, serum biomarkers aspartate aminotransferase (ast) and alanine aminotransferase (alt), and graded liver pathology in a large cohort of diversity outbred mice. |
2024-06-25 |
2024-06-29 |
mouse |
| Vikash Kumar, Rahul Kumar, Guruswami Gurusubramanian, Saurabh Singh Rathore, Vikas Kumar Ro. Morin hydrate ameliorates Di-2-ethylhexyl phthalate (DEHP) induced hepatotoxicity in a mouse model via TNF-α and NF-κβ signaling. 3 Biotech. vol 14. issue 7. 2024-06-24. PMID:38911474. |
the results showed that the mh treatment ameliorated the dehp-induced liver dysfunctions by decreasing the alanine transaminase (alt), aspartate aminotransferase (ast), total bilirubin, liver histoarchitecture, fibrosis, and markers of oxidative stress. |
2024-06-24 |
2024-06-26 |
mouse |
| Amr M Abd El-Hady, Rady M Azzoz, Saeed M Soliman, Ibrahim Y Abdelrahman, Wafaa M Khalil, Said A Al. Studies on the effect of curcumin and quercetin in the liver of male albino rats exposed to gamma irradiation. Histochemistry and cell biology. 2024-06-24. PMID:38913116. |
exposure of rats to whole-body gamma irradiation induced a significant decrease in erythrocyte (rbc), leukocyte (wbcs), platelet count (plt), hemoglobin concentration (hb), hematocrit (hct %), mean erythrocyte hemoglobin (mch), mean corpuscular hemoglobin concentration (mchc), and mean erythrocyte volume (mcv); a high increase in plasma thiobarbituric acid reactive substances (tbars); a nonsignificant statistical decrease in the mean value of serum glutathione (gsh); a significant increase in plasma alanine transferase (alt), aspartate transferase (ast), alkaline phosphates (alp), serum total protein, serum total cholesterol levels, total triglycerides levels, high-density lipoprotein (hdl), and low-density lipoprotein (ldl) levels; and with marked histological changes and structural changes measured by fourier transform infrared (ftir). |
2024-06-24 |
2024-06-26 |
rat |
| Tianming Yu, Le Wang, Yang Cheng, Yun Zhang, Jiankang Zhu, Guangyong Zhang, Sanyuan H. Downregulation of Setdb2 promotes alternative activation of macrophages via the PI3K/Akt pathway to attenuate NAFLD after sleeve gastrectomy. Biochemical and biophysical research communications. vol 726. 2024-06-21. PMID:38905784. |
sg prompted significant weight loss, diminished liver size and liver-to-body weight ratio, and enhanced liver function, evidenced by reduced serum levels of triglycerides (tg), total cholesterol (t-cho), alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2024-06-21 |
2024-06-24 |
mouse |
| S Priyanka, Dnyanesh Morka. AST/ALT Ratio as an indicator of functional severity in chronic heart failure with reduced left ventricular ejection fraction: A prospective cross-sectional study. Indian heart journal. 2024-06-19. PMID:38897408. |
the study was carried out to evaluate the role of the ast (aspartate transaminase)/alt (alanine transaminase) ratio as an indicator of the functional severity in people with chronic heart failure (chf) with reduced left ventricular ejection fraction. |
2024-06-19 |
2024-06-22 |
Not clear |
| Yukari Asahi, Toshiro Arai, Yoshikazu Tanak. Changes in plasma metabolite concentrations and enzyme activities in aging riding horses. Frontiers in veterinary science. vol 11. 2024-06-17. PMID:38881783. |
adiponectin concentrations, plasma superoxide dismutase (sod), and leukocyte amp-activated protein kinase (ampk) activities decreased, while plasma aspartate aminotransferase (ast), alanine aminotransferase (alt), and glutathione peroxidase (gpx) remained unchanged as horses aged. |
2024-06-17 |
2024-06-19 |
Not clear |
| Gautham Kumar, Prabhu M Natarajan, Maher A F Al Shayeb, Anuradha Ganesa. Enzymes in Peri-implant Sulcular Fluid: A Window into Periodontal Health - A Comprehensive Review. Journal of pharmacy & bioallied sciences. vol 16. issue Suppl 2. 2024-06-17. PMID:38882905. |
this essay explores the significance of various enzymes in pisf, including matrix metalloproteinases (mmps), elastase, alkaline phosphatase, acid phosphatase, aspartate aminotransferase (ast), and alanine aminotransferase (alt), in assessing the local inflammatory environment and diagnosing peri-implant diseases. |
2024-06-17 |
2024-06-19 |
Not clear |
| Hongshuai Liu, Yufei Li, Yan Jin, Xin Li, Dongxian Wang, Xiaowen Yu, Zhenyuan Jiang, Guoliang Yin, Suwen Chen, Xin Zhang, Decheng Meng, Wenfei Yu, Wenyin Jiang, Fengxia Zhan. Effects of different natural products in patients with non-alcoholic fatty liver disease-A network meta-analysis of randomized controlled trials. Phytotherapy research : PTR. 2024-06-17. PMID:38886838. |
the results of the network meta-analysis showed that artichoke leaf extract confers a relative advantage in reducing the aspartate aminotransferase (ast) levels (sucra: 99.1%), alanine aminotransferase (alt) levels (sucra: 88.2%) and low-density lipoprotein cholesterol (ldl-c) levels (sucra: 88.9%). |
2024-06-17 |
2024-06-21 |
Not clear |
| A J Cowieson, C A Phillips, G J Mullenix, E S Greene, E Papadopoulou, S Drid. Dynamic responses of blood metabolites to nutrient depletion and repletion in broiler chicken nutrition. Poultry science. vol 103. issue 8. 2024-06-16. PMID:38823292. |
there was a delayed increase in aspartate amino transaminase (ast) associated with the diets with low digestible p and low ame. |
2024-06-16 |
2024-06-18 |
chicken |
| Henry Edwards, Warda Mustfa, Shahaba Tehreem, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Ayesha Ghafoo. Pharmacotherapeutic potential of malvidin to cure imidacloprid induced hepatotoxicity via regulating PI3K/AKT, Nrf-2/Keap-1 and NF-κB pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-06-16. PMID:38880465. |
moreover, imi poisoning increased the levels of alt (alanine aminotransferase), ast (aspartate transaminase), total proteins, albumin, and alp (alkaline phosphatase) in hepatic tissues of rats. |
2024-06-16 |
2024-06-19 |
rat |
| Shen Jin, Jiehao Liu, Yueping Zheng, Jianan Xu, Houyong Fan, Muhammad Faisal Khalil, Youji Wang, Menghong H. Environmentally responsive changes in mucus indicators and microbiota of Chinese sturgeon Acipenser sinensis. Fish & shellfish immunology. 2024-06-14. PMID:38876409. |
the activities of acid phosphatase (acp), alkaline phosphatase (alp), creatine kinase (ck), alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) were significantly higher in indoor fish, serving as indicators of tissue damage (p < 0.05). |
2024-06-14 |
2024-06-17 |
Not clear |
| Rahul Sarma, Sushmita Ray, Nirupam Konwar Baishya, Wahida Sultan. Comparative Study of Levels of Serum Bilirubin, Serum Transaminase, Serum Alkaline Phosphatase, and Prothrombin Time After Laparoscopic Cholecystectomy and Open Cholecystectomy. Cureus. vol 16. issue 5. 2024-06-14. PMID:38872670. |
in the current study, we found significant increases in aspartate transferase (ast), alanine transaminase (alt), and total bilirubin, on day 1 and day 3 after lc but no significant change in alkaline phosphatase (alkp) and pt. it is important for surgeons to know about these transient changes in the immediate postoperative period to avoid misdiagnosis and adopt proper treatment and management. |
2024-06-14 |
2024-06-16 |
Not clear |
| Claudius Mayer, Till Ittermann, Sabine Schipf, Stefan Gross, Simon Kim, Jan Schielke, Robin Bülow, Jens-Peter Kühn, Markus M Lerch, Henry Völzke, Stephan Burkhard Felix, Martin Bahls, Giovanni Targher, Marcus Dörr, Marcello Ricardo Paulista Marku. Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania. European journal of sport science. vol 24. issue 6. 2024-06-14. PMID:38874978. |
specifically, a 10-kg lower hgs was associated with a 0.59% (95% confidence interval [ci]: 0.24-0.94; p = 0.001) higher lfc, a 0.051 µkatal/l (95% ci: 0.005-0.097; p = 0.031) higher gamma-glutamyltransferase (ggt) concentration and a 0.010 µkatal/l (95% ci: 0.001-0.020; p = 0.023) higher aspartate aminotransferase (ast) concentration. |
2024-06-14 |
2024-06-16 |
human |
| Ahmed A A Aioub, Sameh A Abdelnour, Ahmed S Hashem, Mohamed Maher, Sarah I Z Abdel-Wahab, Lamya Ahmed Alkeridis, Mustafa Shukry, Samy M Sayed, Ahmed E A Elsobk. Cinnamon nanoemulsion mitigates acetamiprid-induced hepatic and renal toxicity in rats: biochemical, histopathological, immunohistochemical, and molecular docking analysis. BMC veterinary research. vol 20. issue 1. 2024-06-13. PMID:38867202. |
acdp remarkably raised alanine aminotransferase (alt), aspartate amino transaminase (ast), and alkaline phosphatase (alp) levels.moreover, the histopathological and immunohistochemistry assays discovered a severe toxic effect on the liver and kidney following acdp delivery. |
2024-06-13 |
2024-06-15 |
rat |