| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas Ming-Zher Chee, Ram Prasad Sinnanaidu, Wah-Kheong Cha. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis. Journal of gastroenterology and hepatology. 2024-08-16. PMID:39150005. |
this study aimed to assess the effect of vitamin e on serum markers of liver inflammation, specifically serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, and histology, including resolution of metabolic dysfunction-associated steatohepatitis (mash), in adult patients with masld. |
2024-08-16 |
2024-08-18 |
Not clear |
| Amar Deep, Shweta Kumari, Sayan Malakar, Suchit Swaroop, Sumit Rungt. Risk Factors for Progressive Fibrosis and Cirrhosis in Patients With Chronic Hepatitis C in India. Cureus. vol 16. issue 7. 2024-08-15. PMID:39144860. |
in the chc group, the mean age of diagnosis was 37.68±11.57 years, whereas in the chronic hepatitis c-related liver cirrhosis (chc-lc) group, the mean age was 48.89±12.30 years (p=0.01). compared to normal individuals, chc patients had higher body mass index (bmi) (22.37±1.89 versus 21.72±1.95, p=0.01), alanine aminotransferase (alt) (36.70±7.13 versus 82.78±82.53, p=0.01), and aspartate aminotransferase (ast) (34.96±6.04 versus 80.82±91.77, p=0.01). |
2024-08-15 |
2024-08-17 |
Not clear |
| Suhail M Shaikh, Anuj Varma, Sunil Kumar, Sourya Acharya, Rajvardhan Pati. Navigating Disease Management: A Comprehensive Review of the De Ritis Ratio in Clinical Medicine. Cureus. vol 16. issue 7. 2024-08-14. PMID:39139333. |
the de ritis ratio, defined as the serum aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio, is a widely recognized biochemical marker with significant applications in diagnosing and managing various diseases, particularly liver disorders. |
2024-08-14 |
2024-08-16 |
Not clear |
| Jaeduk Yoshimura Noh, Ai Yoshihara, Shigenori Hiruma, Masahiro Ichikawa, Rei Hirose, Masakazu Koshibu, Hideyuki Imai, Akiko Sankoda, Nami Suzuki, Miho Fukushita, Masako Matsumoto, Natsuko Watanabe, Kiminori Sugino, Koichi It. An Evaluation of the Efficacy of Machine Learning in Predicting Thyrotoxicosis and Hypothyroidism: A Comparative Assessment of Biochemical Test Parameters Used in Different Health Checkups. Internal medicine (Tokyo, Japan). vol 63. issue 16. 2024-08-14. PMID:38171877. |
machine learning was conducted using prediction one on three distinct datasets: the ito dataset (age, sex, and 30 blood tests and biochemical test data), the jhep dataset (age, sex, and total protein,total bilirubin, aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transpeptidase (γgtp), alkaline phosphatase, creatinine (cre), uric acid (ua), and t-cho test data), and the jnd dataset (age, sex, and ast, alt, γgtp, cre, and ua test data). |
2024-08-14 |
2024-08-17 |
Not clear |
| Jia-Yi Tian, Meng Xiao, Wen-Wen Zhao, Xia Wu, Jie Yang, Xiao-Qing Che. Effect of Ilex hainanensis Merr. On HFD-induced nonalcoholic fatty liver disease and rebalance of gut microbiota and bile acids metabolism in mice. Fitoterapia. 2024-08-14. PMID:39142527. |
iha significantly reduced body weight indexs, alanine transaminase (alt) and aspartate transaminase (ast) activities, improved dyslipidemia and insulin resistance (ir), and effectively ameliorated hepatic steatosis in hfd-induced nafld mice. |
2024-08-14 |
2024-08-17 |
mouse |
| Sobia Nisa, Mahroze Fatima, Syed Zakir Hussain Shah, Noor Khan, Beenish Aftab, Wazir Ali, Maryam, Saba Sana, Amber Fatim. Evaluation of growth, antioxidant status, hepatic enzymes and immunity of Nanoselenium-Fed Cirrhinus mrigala. PloS one. vol 19. issue 8. 2024-08-12. PMID:39133684. |
moreover, the highest (p<0.05) values of aspartate transaminase (ast) and alanine transaminase (alt) were recorded in fish fed 2.39 mg/kg se level. |
2024-08-12 |
2024-08-16 |
Not clear |
| Doaa Salah Eddin Mahmoud, Maher A Kamel, Ibrahim El-Tantawy El-Sayed, Reem Binsuwaidan, Elshaymaa I Elmongy, Mohand Kareem Razzaq, Mabrouk Attia Abd Eldaim, El S Abdel Megeed Ahmed, Sara A Shake. Astaxanthin ameliorated isoproterenol induced myocardial infarction via improving the mitochondrial function and antioxidant activity in rats. Journal of biochemical and molecular toxicology. vol 38. issue 8. 2024-08-12. PMID:39132813. |
isoproterenol administration in rats elevated the activities of creatine kinase-mb (ck-mb), aspartate transaminase (ast), lactate dehydrogenase (ldh), and other serum cardiac biomarkers troponin-i activities, oxidative stress biomarkers, malondialdehyde(mda), nuclear factor-kappa b (nf-kb), while it decreased peroxisome proliferator-activated receptor-gamma coactivator (pgc-1α), nuclear factor erythroid-2-related factor 2 (nfe212), mitochondrial transcriptional factor a (mt tfa), mitochondrial dna copy number and glutathione system parameters. |
2024-08-12 |
2024-08-14 |
rat |
| Chen Zhang, Wenguang Lu, Huiru Liu, Lingwei Shen, Mengfan Zhu, Tangtang Zhou, Ling Zhang, Dingfu Xiao, Lijuan Che. Rumen Microbiota Transplantation Alleviates Gossypol Diet-Induced Reproductive, Liver, and Intestinal Damage in Male Mice. Animals : an open access journal from MDPI. vol 14. issue 15. 2024-08-10. PMID:39123732. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels in the blood and lactate dihydrogen-x (ldh-x) levels in the testicular tissue were also measured. |
2024-08-10 |
2024-08-13 |
mouse |
| Alexandra Ioana Danila, Flavius Cioca, Sai Teja Gadde, Sai Praveen Daruvuri, Romulus Timar, Elena Hoge. Prognostic Utility of dNLR, ALRI, APRI, and SII in COVID-19 Patients with Diabetes: A Cross-Sectional Study. Diagnostics (Basel, Switzerland). vol 14. issue 15. 2024-08-10. PMID:39125561. |
this study aims to evaluate the predictive value of inflammatory and liver function markers, specifically derived neutrophil to lymphocyte ratio (dnlr), aspartate aminotransferase (ast)-to-lymphocyte ratio (alri), ast to platelet ratio index (apri), and systemic inflammation index (sii), in covid-19 patients with and without diabetes. |
2024-08-10 |
2024-08-13 |
human |
| Ya Huang, Tao Jin, Wenji Ni, Ying Zhou, Rui Zhang, Dandan Li, Yanhui Wan, Yonghui Shi, Xiaoping Hu, Yong Zhon. Baseline and change in serum lipid and uric acid level over time and incident of nonalcoholic fatty liver disease (NAFLD) in Chinese adults. Scientific reports. vol 14. issue 1. 2024-08-09. PMID:39122810. |
participants who developed nafld were older, male and had higher levels of body mass index (bmi), blood pressure, fasting blood glucose (fbg), triglyceride (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), free triiodothyronine (ft3), uric acid (ua), alanine aminotransferase (alt) and aspartate aminotransferase (ast); and lower levels of high-density lipoprotein cholesterol (hdl-c) and free thyroxine (ft4) (all p values < 0.05). |
2024-08-09 |
2024-08-13 |
human |
| Nguyen Thi Cam Huong, Nguyen Phuong Hai, Chau Van Khanh, Mohamed Gomaa Kamel, Nguyen Van Vinh Chau, Nguyen Thanh Truong, Nguyen Thanh Vinh, Randa Elsheikh, Abdelrahman M Makram, Aya Elsheikh, Hiep Nguyen Canh, Somia Iqtadar, Kenji Hirayama, Pham Thi Le Hoa, Nguyen Tien Hu. New biomarkers for liver involvement by dengue infection in adult Vietnamese patients: a case-control study. BMC infectious diseases. vol 24. issue 1. 2024-08-08. PMID:39118006. |
liver injury with marked elevation of aspartate aminotransferase enzyme (ast) is commonly observed in dengue infection. |
2024-08-08 |
2024-08-12 |
Not clear |
| Domingos Jandondo, Victor Pimentel, João Vigário, Pedro Vienga, Joana M K Sebastião, Anabela Mateus, Felícia Comandante, Euclides Sacomboio, Ana Abecasis, Eunice Manico, Deodete Machado, Zinga David, Jocelyne Neto de Vasconcelos, Joana Morais, Cruz S Sebastiã. Sociodemographic and clinical features related to hepatitis B virus infection among rejected blood donors in Luanda, Angola. Health science reports. vol 7. issue 8. 2024-08-07. PMID:39108675. |
blood donors screened for hbv surface antigen (hbsag) along with aspartate transaminase (ast)/alanine aminotransferase (alt) could play a key in providing safe blood products. |
2024-08-07 |
2024-08-09 |
Not clear |
| Fayza A Abdeldayem, Antonia Lestingi, Salah S Abol-Ela, Mahmoud Alagawany, Tamer Ahmed Ismail, Nadeen G Mostafa, Nahed A El-Shal. Application of butyric acid as a feed additive for improving quail performance and health. Poultry science. vol 103. issue 10. 2024-08-07. PMID:39111236. |
significantly lower alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) were observed at 150 and 200 mg ba/kg (p < 0.05) than the control group. |
2024-08-07 |
2024-08-10 |
Not clear |
| Di Wu, Ze Fan, Xianhu Zheng, Jinnan Li, Meng Zhou, Haitao Zhang, Hong Xu, Shouqi Xie, Liansheng Wan. Evaluation of four novel non-grain protein sources completely replacing soybean meal on growth performance, serum biochemistry, amino acid transport and intestinal health of grass carp (Ctenopharyngodon idella) at different water temperatures. Fish & shellfish immunology. 2024-08-05. PMID:39102969. |
the alanine transaminase (alt), aspartate aminotransferase (ast), total protein (tp) and triglyceride (tg) concentrations of grass carp at 32°c were significantly lower than those at 24°c and 28°c (p < 0.001). |
2024-08-05 |
2024-08-08 |
Not clear |
| Gunjan Upadhyay, Siddabasave Gowda B Gowda, Sidharth P Mishra, Lipsa Rani Nath, Adewale James, Alisha Kulkarni, Yuktee Shrikant, Rohitram Upendram, MathanKumar Marimuthu, Shu-Ping Hui, Shalini Jain, Kain Vasundhara, Hariom Yadav, Ganesh V Halad. Targeted and untargeted lipidomics with integration of liver dynamics and microbiome after dietary reversal of obesogenic diet targeting inflammation-resolution signaling in aging mice. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2024-08-03. PMID:39097080. |
obd also induced hepatic inflammation via increasing alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels and proinflammatory markers ccr2, tnf-α, and il-1β in liver. |
2024-08-03 |
2024-08-06 |
mouse |
| Hideaki Yokoyama, Taku Masuyama, Yuki Tanaka, Taishi Shimazaki, Yuzo Yasui, Takuya Abe, Kouichi Yoshinar. Diacylglycerol O-acyltransferase 1 inhibitor increases plasma alanine aminotransferase and aspartate aminotransferase activities via a shedding of the intestinal villi and an increase in intestinal permeability in rats. Toxicology letters. 2024-08-03. PMID:39096942. |
we previously reported that dgat1 inhibition increased plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities in corn oil-loaded rats via protein kinase c (pkc) activation. |
2024-08-03 |
2024-08-06 |
rat |
| Kaustubh Singh, Mahak Lamba, Vivek Kumar, Pahul Ahuja, K K Gupta, Himanshu Reddy, Ajay Patwa, Sumit Rungta, Sudhir Verm. A Comparative Study of Novel Fibrosis Index and Other Non-invasive Serum Indices for Predicting Fibrosis in Patients of Chronic Liver Disease. Cureus. vol 16. issue 7. 2024-08-02. PMID:39092367. |
we compared the liver stiffness measurement by transient elastography and fibrosis indices, i.e., aspartate transaminase (ast) to alanine transaminase (alt) ratio (aar), ast to platelet ratio index (apri), fibrosis index (fi), fibrosis-4 (fib-4) index, age-platelet index (api), pohl score, and fibrosis cirrhosis index (fci) with novel fibrosis index (nfi), to predict liver fibrosis stages. |
2024-08-02 |
2024-08-05 |
Not clear |
| Manuel Gonzalez, Catherine Higham, Sara Al Janahi, Jean S McGee, Hye Jin Chun. Laboratory Monitoring in Isotretinoin Therapy for Acne: How Long and How Often Must We Test Our Patients? Skinmed. vol 22. issue 2. 2024-08-01. PMID:39089992. |
the frequency of abnormal results for triglycerides, cholesterol, aspartate aminotransferase (ast), and alanine aminotransferase (alt) after 2 months for patients in group a was 21.1%, 13.6%, 8.8%, and 6.0%, respectively, with very rare grade 2 (moderate) or higher abnormalities. |
2024-08-01 |
2024-08-05 |
Not clear |
| Mona Ghias, Hugo Carducci, Leslie-Joy Romero, Asif Haris, Lindsay Sunzer. Hemophagocytic Lymphohistiocytosis (HLH) in an Elderly Male With Epstein-Barr Virus (EBV) Viremia. Cureus. vol 16. issue 7. 2024-08-01. PMID:39087157. |
his initial workup revealed elevated aspartate transaminase (ast), alanine transaminase (alt), bilirubin, and d-dimer. |
2024-08-01 |
2024-08-03 |
Not clear |
| Golam Sagir Ahammad, Se Yeon Jang, In Ho Ki. Effects of micelle silymarin in corn-soybean meal-based diet on laying hens' performance, egg quality, and blood profile, with comparative assessment of blood absorption rates between powdered and micelle silymarin. Poultry science. vol 103. issue 10. 2024-07-30. PMID:39079328. |
regarding blood profile parameters, the study revealed linear reductions for aspartate aminotransferase (ast), alanine aminotransferase (alt), and lactate dehydrogenase (ldh) (p < 0.05), whereas there was a tendency for albumin, triglyceride, and cholesterol (p < 0.10). |
2024-07-30 |
2024-08-02 |
Not clear |