Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yanyang Li, Mofan L. Dihydromyricetin Protects Against Hypoxia/Reoxygenation Injury in Cardiomyocytes by Activating miR-34a-Mediated Notch1 Pathway. Cardiovascular toxicology. 2025-01-26. PMID:39864044. |
treatment with dih prevented h/r-induced increase in the activities of myocardial enzymes aspartate aminotransferase (ast), creatine kinase-mb (ck-mb), and creatine kinase (ck). |
2025-01-26 |
2025-01-28 |
cat |
Maaike C Swets, Steven R Kerr, Brian MacKenna, Louis Fisher, Merel van Wijnen, Diederik Brandwagt, Paul W Schenk, Pieter Fraaij, Leonardus G Visser, Sebastian Bacon, Amir Mehrkar, Alistair Nichol, Patrick Twomey, Philippa C Matthews, Malcolm G Semple, Geert H Groeneveld, Ben Goldacre, Iain Jones, J Kenneth Bailli. Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaçao: Observational Cohort Study. JMIR public health and surveillance. vol 10. 2025-01-26. PMID:39864403. |
cases were defined as acute hepatitis with serum transaminases >500 u/l (aspartate transaminase [ast] or alanine transaminase [alt]) in children aged 16 years or younger. |
2025-01-26 |
2025-01-29 |
Not clear |
Kay-Lee E Strauss, Wendy N Phoswa, Kabelo Mokgalabon. The Impact of Antiretroviral Therapy on Liver Function Among Pregnant Women Living with HIV in Co-Existence with and Without Pre-Eclampsia. Viruses. vol 17. issue 1. 2025-01-25. PMID:39861817. |
however, its use has been associated with adverse liver conditions, particularly hepatotoxicity, often marked by elevated liver enzymes (lees) as demonstrated by an increased aspartate transferase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) in pwlwhiv on art. |
2025-01-25 |
2025-01-28 |
Not clear |
Junjie Wang, Baoyi Chen, Chaofan Cheng, Qingqing Wang, Lili Yang, Zeng Li, Xiongwen L. Timosaponin B II as a novel KEAP1-NRF2 inhibitor to alleviate alcoholic liver disease:Receptor structure-based virtual screening and biological evaluation. Chemico-biological interactions. 2025-01-25. PMID:39862944. |
results indicate that tbii significantly improved ethanol-induced liver injury, inhibited the elevation of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (t-cho), and triglycerides (tg) levels, and reduced lipid droplet accumulation in liver tissues. |
2025-01-25 |
2025-01-28 |
mouse |
Zhimei Tian, Yiyan Cui, Miao Yu, Dun Deng, Zhenming Li, Xianyong Ma, Mingren Q. Reduced Glutathione Promoted Growth Performance by Improving the Jejunal Barrier, Antioxidant Function, and Altering Proteomics of Weaned Piglets. Antioxidants (Basel, Switzerland). vol 14. issue 1. 2025-01-25. PMID:39857441. |
results revealed that dietary gsh1, gsh2, and abx improved body weight and the average daily gain of weaned piglets, and abx decreased albumin content but increased aspartate aminotransferase (ast) activity and the ratio of ast to alanine transaminase levels in plasma. |
2025-01-25 |
2025-01-28 |
Not clear |
Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Che. Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury. Current issues in molecular biology. vol 47. issue 1. 2025-01-24. PMID:39852118. |
additionally, dbj-3 considerably decreased the serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), and triglyceride (tg) levels. |
2025-01-24 |
2025-01-27 |
mouse |
Dyah Aryani Perwitasari, Imaniar Noor Faridah, Haafizah Dania, Didik Setiawan, Triantoro Safari. Machine learning model to predict the adherence of tuberculosis patients experiencing increased levels of liver enzymes in Indonesia. PloS one. vol 20. issue 1. 2025-01-24. PMID:39854377. |
we measured the total bilirubin, aspartate aminotransferase (ast), and alanine aminotransferase (alt) and adherence over the 2nd, 4th, and 6th months of the treatment. |
2025-01-24 |
2025-01-27 |
human |
b' Jing Li, Hui Liu, Yutong Jia, Xiayidanmu Tuniyazi, Xia Liao, Jinlong Zhao, Yun Du, Ziyi Fang, Guodong L\\xc3\\xb. SW033291 promotes liver regeneration after acetaminophen-induced liver injury in mice. Biochemical and biophysical research communications. vol 749. 2025-01-24. PMID:39855045.' |
the results showed that treatment with sw033291 reduces serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, decreases the area of hepatic necrosis, increases glutathione (gsh) levels, and decreases tissue malondialdehyde (mda) content, as well as the expression levels of tumor necrosis factor-alpha (tnf-α), interleukin-1β (il-1β), and interleukin-6 (il-6) in mice with liver injury. |
2025-01-24 |
2025-01-28 |
mouse |
K Al-Taee, L Al-Helal. HYDROGEN SULFIDE AND CYSTATHIONINE γ-LYASE LEVELS FOR PATIENTS WITH PARKINSON'S DISEASE. Georgian medical news. issue 356. 2025-01-24. PMID:39855178. |
the research includes studying the levels of hydrogen sulphide (h2s) and cystathionine γ-lyase (cse) with some biochemical parameters in the serum of patients with pd in mosul city (iraq), which include serotonin (sert), dopamine (da), sphingomyelin (sm), vitamin b12, acetylcholine esterase (ache), monoamine oxidase (mao), creatine kinase (ck), aspartate aminotransferase (ast), alanine aminotransferase (alt). |
2025-01-24 |
2025-01-28 |
Not clear |
Shanshan Chen, Lu Huang, Yili Chu, Jiangshan Lian, Hui Shao, Tingting Wang, Xuehan Zou, Haijun Huan. Noninvasive diagnosis model for predicting significant liver inflammation in patients with chronic hepatitis B in the immune-tolerant phase. Scientific reports. vol 15. issue 1. 2025-01-24. PMID:39856182. |
age, aspartate aminotransferase (ast), prothrombin (pt), albumin (alb) and hepatitis b virus dna (hbv dna) were identified as independent predictors of significant liver inflammation in the immune-tolerant phase, and a nomogram was constructed based on these indicators. |
2025-01-24 |
2025-01-28 |
Not clear |
Yi Zhang, Lingtong Huang, Zheyue Shu, Wei Wu, Hongliu Cai, Yu Sh. Prediction of Prognosis in Patients with Severe Fever with Thrombocytopenia Syndrome. Japanese journal of infectious diseases. vol 78. issue 1. 2025-01-22. PMID:39343559. |
statistically significant differences were observed in the neutrophil percentage, lymphocyte percentage, neutrophil-to-lymphocyte ratio, platelet (plt) count, aspartate aminotransferase (ast)/alanine transaminase (alt) ratio, ast, blood urea nitrogen, lactate dehydrogenase, hydroxybutyrate dehydrogenase, thromboplastin time, and activated partial thromboplastin time between the two groups. |
2025-01-22 |
2025-01-25 |
Not clear |
Mahmoud El Safadi, Tawaf Ali Shah, Syeda Sania Zahara, Yousef A Bin Jardan, Mohammed Bourhi. Regulation of TGF-β1, PI3K/PIP3/Akt, Nrf-2/Keap-1 and NF-κB signaling pathways to avert bifenthrin induced hepatic injury: A palliative role of daidzein. Tissue & cell. vol 93. 2025-01-22. PMID:39842227. |
bfn promoted the levels of matrix metallopeptidase 2 (mmp-2), procollagen iii n-terminal pro-peptide (piiinp), alkaline phosphatase (alp), transforming growth factor-beta-1 (tgf-β1), aspartate aminotransferase (ast), tissue inhibitor of matrix metalloproteinases 1 (timp1), and alanine aminotransferase (alt). |
2025-01-22 |
2025-01-25 |
rat |
Amro M Hassan, Heba H Orabi, Muhammad Abdel-Gawad, Omran Mohamed, Safwat S Sawy, Mona M Abdelmeguid, Mohamed A Bashir, Emad Abdelrazzak, Khalid Ead, Mustafa A Harid. Changes in Vascular Endothelial Growth Factor and Development of Hepatocellular Carcinoma in Direct-Acting Antiviral Drugs (DAAs)-Treated Hepatitis C Virus (HCV) Patients. Cureus. vol 16. issue 12. 2025-01-20. PMID:39830567. |
hcv-rna, aspartate aminotransferase (ast) to platelet ratio index (apri), and fibrosis-4 index scores, liver function tests, serum vegf, alpha-fetoprotein (afp), and abdominal ultrasound were done at baseline, 4 weeks after starting treatment, at the end of treatment, and 12 weeks after treatment. |
2025-01-20 |
2025-01-23 |
Not clear |
Jun-Chao Song, Zhe Peng, Yan-Qi Ning, Alainaa Refaie, Cheng-Fei Wang, Meng Liu, Lv-Hui Su. A novel zearalenone lactonase can effectively mitigate zearalenone-induced reproductive toxicity in gilts. Toxicon : official journal of the International Society on Toxinology. 2025-01-20. PMID:39832570. |
compared to the con group, zen treatment reduced the body weight gain of the gilts, increased vulva area and vaginal and uterus indices, and increased serum aspartate aminotransferase (ast) activity and estradiol (e2) concentration. |
2025-01-20 |
2025-01-23 |
Not clear |
Khalid J Alzahrani, Mahmoud El Safadi, Fuad M Alzahrani, Ali Akbar, Naif O Alsiwiehr. Bromoxynil induced hepatic toxicity via dysregulating TLR4/MyD88, JAK1/STAT3 and NF-κB signaling pathways: A dose-dependent investigation. Tissue & cell. vol 93. 2025-01-19. PMID:39827709. |
however, an elevation was observed in the levels of alanine transaminase (alt), gamma-glutamyl transpeptidase (ggt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) while a reduction in the levels of total proteins and albumin was observed after high dose (20 mg/kg, 40 mg/kg) of bml. |
2025-01-19 |
2025-01-23 |
rat |
Ibrahim Talat El-Ratel, Aml Mekawy, Sara H M Hassab, Sameh Abdelnou. Enhancing growing rabbit heat stress resilience through dietary supplementation with natural antioxidants. BMC veterinary research. vol 21. issue 1. 2025-01-18. PMID:39827123. |
aspartate transaminase (ast), triglycerides, and creatinine levels were decreased with all additives as compared to the control group (p < 0.05). |
2025-01-18 |
2025-01-31 |
rabbit |
Nicodemus Emeka Nwankwo, Emmanuel Henry Ezenabor, Obiora Emmanuel Abonyi, Bartholomew Onyekachi Okol. Antiplasmodial Potentials, Phytocompounds, and the Possible Toxic Effects of Administration of Ethylacetate Extract of Spondias mombin Linn. Chemistry & biodiversity. 2025-01-17. PMID:39629680. |
liver function tests showed mixed effects, with elevated aspartate aminotransferase (ast), alkaline phosphatase (alp), and total bilirubin (tb) levels at some doses, yet decreased alanine aminotransferase (alt) at the highest dose, suggesting possible hepatoprotective effects. |
2025-01-17 |
2025-01-20 |
mouse |
Liangyu Zhang, Leilei Gu, Hongqun Qia. 26-Week Repeated-Dose Toxicity Study of a Novel Antiarrhythmic Drug Sulcardine Sulfate in Sprague-Dawley Rats. Journal of applied toxicology : JAT. 2025-01-17. PMID:39821320. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in male rats significantly increased in the medium- and high-dose groups, whereas female rats in these groups showed a significant rise in alkaline phosphatase (alp) levels, accompanied by varying degrees of weight gain in the liver and lungs. |
2025-01-17 |
2025-01-20 |
rat |
Iqra Nasim, Nadia Ghani, Rab Nawaz, Emilio Mateev, Yousef A Bin Jarda. Investigating the impact of Multiwalled Carbon Nanotubes exposure on enzymatic activities and histopathological variations in Swiss albino mice. Scientific reports. vol 15. issue 1. 2025-01-17. PMID:39824850. |
an enzyme-linked immunosorbent test (elisa) was used to measure many enzyme assays, such as angiotensin converting enzymes (ace), alanine aminotransferase (alt), aspartate aminotransferase (ast), and nicotinamide adenine dinucleotide phosphate (nadph) oxidase enzyme. |
2025-01-17 |
2025-01-21 |
mouse |
Aryan Tavakoli, Camellia Akhgarjand, Hastimansooreh Ansar, Hirad Houjaghani, Amirhossein Khormani, Kurosh Djafarian, Abdolrahman Rostamian, Mahsa Ranjbar, Gholamreza Mohammadi Farsan. The effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized controlled trial. Scientific reports. vol 15. issue 1. 2025-01-17. PMID:39825120. |
liver enzymes aspartate transaminase (ast) and alanine transaminase (alt) also decreased significantly in the if group (p = 0.02 and p = 0.03, respectively). |
2025-01-17 |
2025-01-21 |
Not clear |