| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ilaria Giangrandi, Monica Dinu, Antonia Napoletano, Valentina Maggini, Niccolò Lombardi, Giada Crescioli, Eugenia Gallo, Vittorio Mascherini, Michele Antonelli, Davide Donelli, Alfredo Vannacci, Fabio Firenzuoli, Francesco Sof. Licorice and liver function in patients with primary liver disease: A systematic review and meta-analysis of RCTs. Phytotherapy research : PTR. 2024-07-30. PMID:39079711. |
licorice significantly reduced alanine aminotransferase (alt) by 15.63 u/l (95% ci: -25.08, -6.18; p = 0.001) and aspartate aminotransferase (ast) by 7.37 u/l (95% ci: -13.13, -1.61; p = 0.01) compared to control groups. |
2024-07-30 |
2024-08-02 |
human |
| Xiaoting Ge, Junxiu He, Yuan Zheng, Qiuyue Wang, Hong Cheng, Yu Bao, Sencai Lin, Xiaobo Yan. Association of Blood Metals and Metal Mixtures with the Myocardial Enzyme Profile: An Occupational Population-Based Study in China. Biological trace element research. 2024-07-28. PMID:39069562. |
to investigate a cross-sectional association between blood metal mixture and myocardial enzyme profile, we quantified creatine kinase (ck), creatine kinase-mb (ck-mb), lactate dehydrogenase (ld), α-hydroxybutyrate dehydrogenase (α-hbd), and aspartate transaminase (ast) levels among participants from the manganese-exposed workers healthy cohort (mewhc) (n = 544). |
2024-07-28 |
2024-08-02 |
human |
| Minh H Tran, Jie Gao, Xinzhe Wang, Ruisheng Liu, Colby L Parris, Carlos Esquivel, Yingxiang Fan, Lei Wan. Enhancing Liver Transplant Outcomes through Liver Precooling to Mitigate Inflammatory Response and Protect Mitochondrial Function. Biomedicines. vol 12. issue 7. 2024-07-27. PMID:39062048. |
liver precooling exhibited a significant improvement in graft function, revealing more than a 47% decrease in plasma aspartate transaminase (ast) and alanine aminotransferase (alt) levels, coupled with a remarkable reduction of approximately 50% in liver graft histological damage compared to the control group. |
2024-07-27 |
2024-07-29 |
mouse |
| Xuan Shen, Wenxing Zheng, Xinna Du, Yuping Chen, Xianping Song, Liucai Yang, Qi Yua. The role of C5aR1-mediated hepatic macrophage efferocytosis in NASH. Scientific reports. vol 14. issue 1. 2024-07-26. PMID:39060563. |
meanwhile, we verified its positive correlation with patients' serum alanine transaminase (alt) and aspartate transaminase (ast) levels. |
2024-07-26 |
2024-07-29 |
mouse |
| Tajudeen Olanrewaju Yahaya, Abdulgafar Bala Ibrahim, Abdulrahman Sani Kalgo, Mutiyat Kehinde Adewale, Chikelu Chinelo Emmanuela, Baliqees Abdulkadir, Adamu Zainab Fari, Asiya Koko Attahiru, Abdullahi Saadatu, Joseph Dahali Wand. Microplastics exposure altered hematological and lipid profiles as well as liver and kidney function parameters in albino rats (Rattus norvegicus). Environmental analysis, health and toxicology. vol 39. issue 2. 2024-07-26. PMID:39054835. |
the liver function parameters, including total protein (tp), albumin (alb), aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp), were elevated, indicating liver damage. |
2024-07-26 |
2024-07-28 |
human |
| Meiqi Wan, Hua Gao, Xiaoyan Liu, Youbo Zhan. Rutaecarpine Aggravates Acetaminophen-Induced Acute Liver Injury by Inducing CYP1A2. Toxics. vol 12. issue 7. 2024-07-26. PMID:39058167. |
the liver pathological changes were evaluated with hematoxylin and eosin staining, while the aspartate aminotransferase (ast) and alanine aminotransferase (ast) levels in plasma were measured to assess the liver damage. |
2024-07-26 |
2024-07-28 |
mouse |
| Jia-Hung Lin, Chi-Huei Lin, Yi-Wei Kuo, Chorng-An Liao, Jui-Fen Chen, Shin-Yu Tsai, Ching-Min Li, Yu-Chieh Hsu, Yen-Yu Huang, Ko-Chiang Hsia, Yao-Tsung Yeh, Hsieh-Hsun H. Probiotic Lactobacillus fermentum TSF331, Lactobacillus reuteri TSR332, and Lactobacillus plantarum TSP05 improved liver function and uric acid management-A pilot study. PloS one. vol 19. issue 7. 2024-07-25. PMID:39046973. |
test subjects with abnormal levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and ua were recruited and randomly allocated into six groups. |
2024-07-25 |
2024-07-28 |
human |
| Pitchumani Sivakumar, Michelle Saul, Douglas Robinson, Lindsay E King, Neeta B Ami. SomaLogic proteomics reveals new biomarkers and provides mechanistic, clinical insights into Acetyl coA Carboxylase (ACC) inhibition in Non-alcoholic Steatohepatitis (NASH). Scientific reports. vol 14. issue 1. 2024-07-25. PMID:39048608. |
somasignal nash probability scores and expression data for 7000+ analytes were analyzed to identify potential biomarkers associated with baseline clinical measures of nafld/nash [magnetic resonance imaging-proton density fat fraction (mri-pdff), alanine aminotransferase (alt) and aspartate aminotransferase (ast)] as well as biomarkers of treatment response to acci. |
2024-07-25 |
2024-07-28 |
Not clear |
| Yanni Ma, Xintong Yao, Yunding Zou, Baiping Liu, Yuanze Zhou, Zhenzhen Guo, Qi Yao, Shuangnian Xu, Hui L. Ticlopidine protects hepatic ischemia-reperfusion injury via suppressing ferroptosis. Biochemical and biophysical research communications. vol 733. 2024-07-25. PMID:39053102. |
using a c57bl/6j mouse model, we demonstrated that prophylactic ticlopidine treatment significantly reduced necrotic and fibrotic areas in liver tissues, as well as serum levels of alanine transaminase (alt) and aspartate aminotransferase (ast). |
2024-07-25 |
2024-07-28 |
mouse |
| Mpwaga Alatwinusa Yohana, Gyan Watson Ray, Qihui Yang, Kou Shiyu, Beiping Tan, Jiahua Wu, Minling Mao, Zhan Bo Ge, Lan Fen. Comprehensive analysis of butyric acid impact on immunology, histopathology, gene expression, and metabolomic responses in pacific shrimp experiencing cold stress. Comparative biochemistry and physiology. Part D, Genomics & proteomics. vol 52. 2024-07-25. PMID:39053237. |
conversely, the control groups showed an increase in aspartate aminotransferase (ast) and alanine transaminase (alt) activity. |
2024-07-25 |
2024-07-28 |
Not clear |
| Charlotte Evans, Finlay Mackenzie, Rachel Marringto. Variation in liver function testing and the effect of pyridoxal-5-phosphate on ALT, AST and FIB-4 results. Annals of clinical biochemistry. 2024-07-25. PMID:39054266. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) are key markers of hepatocellular injury. |
2024-07-25 |
2024-07-28 |
Not clear |
| Allison B Chambliss, Rhona J Souers, Jonathan R Genzen, David M Manthe. Reported Awareness and Use of Pyridoxal-5'-Phosphate Supplementation in Alanine Aminotransferase and Aspartate Aminotransferase Assay Reagents: A Survey by the College of American Pathologists Clinical Chemistry Committee. Archives of pathology & laboratory medicine. 2024-07-24. PMID:39048110. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) assay reagents are available both with and without supplementation with pyridoxal-5'-phosphate (p5p; the active form of vitamin b6), a catalytic cofactor required for their enzymatic reactions. |
2024-07-24 |
2024-07-28 |
Not clear |
| A Koperska, M Moszak, A Seraszek-Jaros, P Bogdanski, M Szulinsk. Does berberine impact anthropometric, hepatic, and metabolic parameters in patients with metabolic dysfunction-associated fatty liver disease? Randomized, double-blind placebo-controlled trial. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042390. |
in the bbr group, we found significant correlations between changes and amelioration of certain variables: Δ body mass index (bmi) correlated with Δalt (r=0.47; p=0.0089) and d aspartate aminotransferase (ast) (r=0.47; p=0.0081) levels; Δ trunk fat with Δ fatty liver index (fli) (r=0.55; p=0.0337), Δ homeostasis model assessment for insulin resistant index (homa-ir) (r=0.37; p=0.0020), and ast (r=0.42; p=0.0202); d the de ritis ratio correlated with Δ fibrosis-4 index (fib-4) levels (r=0.59; p=0.0011); and Δfli correlated with Δhoma-ir (r=0.37; p=0.0409) and Δ visceral adiposity index (vai) (r=0.54; p=0.0019), while no significant differences were observed in the placebo group. |
2024-07-23 |
2024-07-25 |
Not clear |
| X Yan, K-J Mu, Q Wen, J Bian, D Yang, W-N Gao, W-M Zhan. Analyzing the impact of acupuncture in conjunction with a Quantum lipid-lowering device on hyperlipidemic rats: insights into adenosine monophosphate-activated protein kinase signaling, blood lipids, and gut microbiota. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042391. |
elisa results showed that compared with the model group, acup + quantum group could reduce the levels of total cholesterol (tc), triglycerides (tg), low-density lipoprotein-cholesterol (ldl-c), aspartate transaminase (ast) and aspartate transaminase (alt) in rats with hyperlipidemia (p<0.01), and increase the level of high-density lipoprotein-cholesterol (hdl-c) (p<0.01). |
2024-07-23 |
2024-07-25 |
rat |
| Chen Rong Phang, Azfar Farooqi, Yashvir Sangwa. Unmasking the Unusual: Cryptococcal Pericarditis in a Patient with Liver Failure - a Rare Occurrence. The American journal of case reports. vol 25. 2024-07-22. PMID:39037967. |
initial laboratory workup revealed thrombocytopenia, transaminitis (aspartate transaminase (ast) level of 502 iu/l, alanine transaminase (alt) level of 82 iu/l), hyperbilirubinemia (total bilirubin of 15.7 mg/dl), international nationalized ratio (inr) of 3.6, and lactic acidosis (lactic acid of 11.7 mmol/l). |
2024-07-22 |
2024-07-25 |
human |
| George J Dugbartey, Stephen Atule, Karl K Alornyo, Ismaila Adam. Hepatoprotective potential of alpha-lipoic acid against gliclazide-induced liver injury in high-glucose-exposed human liver cells and experimental type 2 diabetic rats. Biochemical pharmacology. 2024-07-22. PMID:39038553. |
abbreviations: ala, alpha-lipoic acid; alt, alanine aminotransferase; alp, alkaline phosphatase; ampk, adenosine monophosphate-activated protein kinase; ast, aspartate aminotransferase; atp, adenosine triphosphate; dmem, dulbecco's modified eagle medium; edta, ethylenediaminetetraacetic acid; fbg, fasting blood glucose; fbs, fetal bovine serum; glc, gliclazide; glut4, glucose transporter type 4; gsh, glutathione; h&e, hematoxylin/eosin; hba1c, glycosylated haemoglobin a1c; hc, healthy control; hg, hyperglycemic group; homa-β, homeostasis model assessment of β-cell function; il-1β, interleukin-1β; il-6, interleukin-6; inos, inducible nitric oxide synthase; k |
2024-07-22 |
2024-07-25 |
human |
| Heba A Nasr, Nasr-Eldin M Aref, Mahmoud R Abd Ellah, Mohammed Ahmed Hamdy Abdelhakie. Cardiac biomarkers as tools in the prediction and diagnosis of traumatic pericarditis and traumatic reticuloperitonitis in cattle and buffaloes. BMC veterinary research. vol 20. issue 1. 2024-07-20. PMID:39033105. |
the present study was carried out to evaluate the diagnostic significance of cardiac troponin i rapid test cassette and other cardiac biomarkers including serum cardiac troponin i (ctn i), creatine kinase-myocardial band (ck-mb), lactate dehydrogenase (ldh), and aspartate aminotransferase enzyme (ast), in confirmed cases of traumatic pericarditis (tp) and/or traumatic reticuleoperitonitis (trp) in cattle and buffaloes. |
2024-07-20 |
2024-07-24 |
cattle |
| Q Zhang, Y Jiang, Y Qin, J Liu, Y Xie, L Zhang, K Li, X Wang, G Li. Linoleic Acid Alleviates Lipopolysaccharide Induced Acute Liver Injury via Activation of Nrf2. Physiological research. vol 73. issue 3. 2024-07-19. PMID:39027955. |
the results indicated that treatment with la alleviated the histopathological abnormalities in the hepatic and plasma levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and glutathione-s-transferase (gst) in mice with lps exposure. |
2024-07-19 |
2024-07-21 |
mouse |
| Victor Menezes Tunholi, Ludimila Santos Amaral, Natânia do Carmo Sperandio, Lorena Souza Castro Altoé, Vinícius Menezes Tunholi-Alves, Juberlan Garcia, Ester Maria Mota, Melissa Carvalho Machado do Couto-Chambarelli, Caio Márcio de Oliveira Monteiro, Isabella Vilhena Freire Martin. Metabolic disruptions in Biomphalaria glabrata induced by Heterorhabditis bacteriophora HP88: implications for entomopathogenic nematodes in biological control. Experimental parasitology. 2024-07-17. PMID:39019304. |
in this study, the effect of exposure time (24 or 48 hours) of heterorhabditis bacteriophora hp88 on the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast), as well as the concentration of total proteins, uric acid, and urea in the hemolymph of biomphalaria glabrata, were investigated. |
2024-07-17 |
2024-07-20 |
Not clear |
| Sevginur Akdas, Nuray Yaziha. From NAFLD to MASLD: Meta-analysis and systematic review of NAFLD patients in Turkiye in terms of metabolic profile and MASLD potential. Hepatology forum. vol 5. issue 3. 2024-07-16. PMID:39006144. |
according to the meta-analysis results, there were significant increases in waist circumferences (mean difference: 10.90, p<0.00001), homa-ir (mean difference: 2.13, p<0.00001), aspartate aminotransferase (ast) (mean difference: 17.82, p<0.00001), systolic blood pressure (sbp) (mean difference: 5.86, p<0.00001), and c-reactive protein (crp) levels (mean difference: 0.95, p<0.00001). |
2024-07-16 |
2024-07-18 |
Not clear |