Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Minghao Geng, Yi Cheng, Leizhen Duan, Guangshen Dong, Shuo Yang, Xuecheng Jiao, Weihua Jia, Hui Huang, Ming Dou, Xiaoli Fu, Fangfang Yu, Yuhui Du, Guoyu Zhou, Yue B. Inflammation May Mediate the Effects of Fluoride on Liver and Kidney Function of Adults: Cross-Sectional Studies in China. Biological trace element research. 2025-03-21. PMID:40117029. |
urine and blood samples were collected for determinations of urinary fluoride (uf), aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tbil), blood urea nitrogen (bun), serum creatinine (scr), serum uric acid (sua), and white blood cell (wbc) counts. |
2025-03-21 |
2025-03-24 |
human |
Zhe Liu, Jing Hou, MeiYuan Tian, YaoGang Zhang, DengLiang Huang, Na Zhao, Yanyan Ma, Sen Cu. Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling. Cellular signalling. 2025-03-20. PMID:40112904. |
compared with those in the 2200 m hfd group, body weight, triglyceride (tg), total cholesterol (tc), amino alanine transferase (alt), aspartate transaminase (ast), and lipid accumulation were lower in the 4500 m hfd group (p < 0.05). |
2025-03-20 |
2025-03-23 |
Not clear |
Zhongfeng Cheng, Kerun Cheng, Yan Tang, Xueqiong Duan, Yangshan Fu, Hongdan Duan, Yong Y. α-Amanitin aggravates hepatic injury by activating oxidative stress and mitophagy via peroxiredoxin 6 inhibition. Immunologic research. vol 73. issue 1. 2025-03-20. PMID:40108092. |
in addition, the levels of alanine aminotransferase (alt), aspartate transaminase (ast) and mitochondrial reactive oxygen species (mtros) were observed to increase in the α-ama-treated groups, whereas antioxidants superoxide dismutase (sod) levels were reduced. |
2025-03-20 |
2025-03-22 |
mouse |
Dachuan Jin, Shunqin Jin, Guoping Sheng, Zhongfeng Cui, Peng Gao, Guangming L. Effects of Curcumin on Postmenopausal Women's Health: A Systematic Review and Meta-Analysis. Phytotherapy research : PTR. 2025-03-19. PMID:40105038. |
we found that curcumin reduced systolic (smd -0.51, 95% ci -0.83 to 0.19, p = 0.002) and diastolic blood pressure (smd -0.63, 95% ci -0.96 to -0.30, p = 0.005), increased total antioxidant capacity (smd 0.93, 95% ci 0.15 to 1.72, p = 0.020) and superoxide dismutase levels (smd 0.30, 95% ci 0.04 to 0.56, p = 0.026), decreased aspartate aminotransferase (ast) (smd -0.36, 95% ci -0.66 to -0.06, p = 0.020), and improved vasomotor (smd -0.39, 95% ci -0.65 to -0.13, p = 0.003) symptoms. |
2025-03-19 |
2025-03-21 |
human |
Muhammad Tahir, Noor Khan, Mahroze Fatima, Naveed Ul Haque, Simon J Davie. Bioavailability of zinc from different organic zinc chelates and their effect on the growth, whole body, tissue zinc content, enzymes activity and proximate composition of L. rohita. PloS one. vol 20. issue 3. 2025-03-19. PMID:40106486. |
blood serum parameters, including alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp), remained lower (29.65 ± 0.85 u/ml, 84.76 ± 2.45 u/ml, and 212.87 ± 6.14 u/ml), in fish fed zinc gluconate respectively. |
2025-03-19 |
2025-03-22 |
cat |
Noha Madbouly Taha, Mai A Salem, Mohamed A El-Saied, Faten F Mohammed, Mohamed Kamel, Mohamed M El-Bahy, Reem M Ramada. Multifaceted analysis of equine cystic echinococcosis: genotyping, immunopathology, and screening of repurposed drugs against E. equinus protoscolices. BMC veterinary research. vol 21. issue 1. 2025-03-18. PMID:40098107. |
serum biochemical analysis showed elevated aspartate transaminase (ast), alkaline phosphatase (alp), and globulin levels, alongside decreased albumin compared to non-infected controls. |
2025-03-18 |
2025-03-20 |
Not clear |
Araya Supawat, Jintana Sattayasai, Sirinapa Rungruang, Jirayut Kaewmor, Kusavadee Sangdee, Aphidech Sangde. Protective Effect of Polycephalomyces nipponicus (Ascomycota) Against Alcohol-Induced Liver Injury and Alcohol Intoxication in ICR Mice. International journal of medicinal mushrooms. vol 27. issue 5. 2025-03-17. PMID:40094339. |
liver enzyme activities-alcohol dehydrogenase (adh), aldehyde dehydrogenase (aldh), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp)-and blood triglyceride and cholesterol levels were measured, with motor coordination assessed post-ethanol. |
2025-03-17 |
2025-03-20 |
mouse |
Jing Xiao, Gaoyong Deng, He Ling, Wencai L. Constructing a nomogram model for patients with cervical spondylotic myelopathy. Scientific reports. vol 15. issue 1. 2025-03-15. PMID:40087491. |
the results showed that platelets (plt) (1.005 [1.001, 1.009], p = 0.021), albumin (alb) (0.891 [0.818, 0.97], p = 0.008), aspartate aminotransferase (ast) (1.031 [1.002, 1.061], p = 0.035), alanine aminotransferase (alt) (0.958 [0.92, 0.998], p = 0.037), and fibrinogen (fib) (0.654 [0.464, 0.921], p = 0.015) were independent predictors. |
2025-03-15 |
2025-03-18 |
Not clear |
Mengru Chen, Yifei He, Yimin Jia, Lei Wu, Ruqian Zha. Liver transcriptome response to avian pathogenic Escherichia coli infection in broilers with corticosterone treatment. Poultry science. vol 104. issue 5. 2025-03-15. PMID:40088534. |
additionally, plasma aspartate aminotransferase (ast), ast to alanine aminotransferase (ast/alt) ratio, and lactate dehydrogenase (ldh) levels increased significantly (p < 0.01). |
2025-03-15 |
2025-03-18 |
Not clear |
Yoshiki Katsumi, Yui Nishimura, Sachiko Goto, Seiichiro Ozawa, Tomoko Nishiura, Akira Kotera, Yoshiyuki Kawahara, Shiori Higashikawa, Rina Iwasaki, Yutaka Toriiminami, Norio Asai, Naohisa Fujit. Case Report: HLA-DRB1 04:01 found in a child with adenovirus type 2 -linked hepatitis. Frontiers in immunology. vol 16. 2025-03-13. PMID:40079016. |
two weeks after the initial visit, her aspartate aminotransferase (ast) and alanine aminotransferase (alt) concentrations increased to 1558 and 1843 iu/l, respectively. |
2025-03-13 |
2025-03-15 |
human |
Shenao Zhan, Lianchi Wu, Yujie Lv, Weichen Huang, Chaoyue Ge, Zhaoying Hu, Xinyu Shen, Gang Lin, Dongyou Yu, Bing Li. Lactobacillus reuteri alleviates diquat induced hepatic impairment and mitochondrial dysfunction via activation of the Nrf2 antioxidant system and suppression of NF-κB inflammatory response. Poultry science. vol 104. issue 5. 2025-03-12. PMID:40073635. |
the results demonstrated that dq exposure induced oxidative damages and lipid metabolism disorders manifested as the elevated alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, triglyceride (tc) contents in serum and lipid accumulation in liver. |
2025-03-12 |
2025-03-15 |
Not clear |
Yehudit Shabat, Devorah Rotnemer-Golinkin, Lidya Zolotarov, Yaron Ila. Inter-organ correlations in inflammation regulation: a novel biological paradigm in a murine model. Journal of medicine and life. vol 18. issue 1. 2025-03-12. PMID:40071160. |
mice were tested for serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels. |
2025-03-12 |
2025-03-14 |
mouse |
Zongshun Chen, Jing Zhang, Wei Chen, Xueyi Chen, Da-Lin Lu, Junjie L. Serum Enzymes and Pathologic Complete Response to the Addition of Targeted Therapy in Neoadjuvant Chemotherapy for HER2-Positive Breast Cancer Patients. Annals of surgical oncology. 2025-03-11. PMID:40067607. |
this study investigated the association between circulating alanine aminotransferase (alt), aspartate aminotransferase (ast), creatine kinase (ck), lactate dehydrogenase (ldh), and gamma-glutamyltransferase (ggt) and the pathologic complete response (pcr) in patients with human epidermal growth factor receptor 2 (her2)-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab (h) and pertuzumab (p). |
2025-03-11 |
2025-03-14 |
human |
Jing Li, Xueyong Hu, Tingfeng Liang, Hongzheng Zhang, Chaosheng Y. Mechanism of skull base osteoradionecrosis explored through laboratory assessment with propensity score-matched analysis. Scientific reports. vol 15. issue 1. 2025-03-11. PMID:40065029. |
univariate logistic regression analysis revealed statistically significant differences in hemorrhage (hb), erythrocytes (rbc), albumin (alb), platelets (plt), indirect bilirubin (ibil), globulin (glo), aspartate aminotransferase (ast), and fibrinogen (fg) between the two groups (p < 0.05). |
2025-03-11 |
2025-03-13 |
Not clear |
Esmaeel Babaeenezhad, Navid Farahmandian, Mohammadjavad Sotoudeheian, Omid Dezfoulian, Elaheh Askari, Niloofar Taghipour, Sahar Yarahmad. Resveratrol Relieves Hepatic Steatosis and Enhances the Effects of Atorvastatin in a Mouse Model of NAFLD by Regulating the Renin-Angiotensin System, Oxidative Stress, and Inflammation. Food science & nutrition. vol 13. issue 3. 2025-03-06. PMID:40046578. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities were increased in nafld mice. |
2025-03-06 |
2025-03-08 |
mouse |
Goran Bokan, Marijana Kovacevic, Natasa Zdravkovic, Dejan Bokonjic, Maksim Kovacevic, Verica Prodanovic, Zoran Mavij. Significance of Laboratory Findings and Esophageal Varices in Male Patients With Decompensated Alcoholic Liver Cirrhosis: A Single-Center Experience. Cureus. vol 17. issue 1. 2025-03-04. PMID:40027007. |
among biochemical parameters, the most common findings were increased bilirubin in 98 patients (79.67%), aspartate aminotransferase (ast) in 111 patients (90.24%), gamma-glutamyl transferase (ggt) in 109 patients (88.61%), and d-dimer in 110 patients (89.44%), while albumin levels were decreased in 107 patients (87.00%). |
2025-03-04 |
2025-03-06 |
human |
Bichen Zhao, Ming Li, Huijing Zhang, Jingyi Wang, Wanli Zhao, Yue Yang, Muhammad Usman, Juan J Loor, Chuang X. M1 polarization of hepatic macrophages in cows with subclinical ketosis is an important cause of liver injury. Journal of dairy science. vol 108. issue 3. 2025-03-03. PMID:39647630. |
serum biochemical parameters were measured using an automatic biochemical analyzer, which indicated higher serum levels of bhba and nonesterified fatty acids and an upregulation of liver injury indicators (aspartate aminotransferase [ast], alanine aminotransferase [alt], total protein, globulin) in sck cows compared with healthy cows. |
2025-03-03 |
2025-03-06 |
Not clear |
Nan Ma, Rong Li, Gui-Fang Zhang, Ruo-Han Gao, Dong-Jie Zhan. Fermentation-enriched quinoa β-glucan ameliorates disturbed gut microbiota and metabolism in type 2 diabetes mellitus mice. International journal of biological macromolecules. 2025-03-03. PMID:40032090. |
additionally, liver and pancreatic function improved, as evidenced by decreased levels of malondialdehyde (mda), aspartate transaminase (ast), and alanine transaminase (alt). |
2025-03-03 |
2025-03-06 |
mouse |
Mohid Bin Tahir, Arham Bin Tahir, Fatima Meer, Iftikhar Hussain, Md Shamimur Rahman, Muhammad Rawal Saeed, Ubaid Ur Rehman, Rana Shahzaib Ali, Abdul Eizad Asif, Ali Ahmed, Tayyab Mumtaz Kha. Association Between Serum Triglyceride Levels and the Severity of Acute Pancreatitis: A Retrospective Study. Cureus. vol 17. issue 1. 2025-02-27. PMID:40013171. |
values of the variables including gender, age, white blood cell (wbc) count, serum aspartate transaminase (ast) levels, serum blood glucose levels, serum lactate dehydrogenase (ldh) levels, ranson score, serum amylase levels, serum lipase levels, body mass index, serum tg levels, and length of hospital stay were significantly (p < 0.05) higher among the patients with severe ap. |
2025-02-27 |
2025-03-01 |
Not clear |
Muhammet Yusuf Tepebaşi, Halil Aşci, Esma Selçuk, Öznur Kolay, Adem Milletsever, Melda Şahin, Özlem Özme. Investigation of the Theranekron Ameliorative Effect on Sepsis-Induced Hepatotoxicity via Inflammation and Oxidative Stress Pathways. Cell biochemistry and biophysics. 2025-02-24. PMID:39992615. |
significant liver damage was also seen in this group, as evidenced by elevated levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) and decreased albumin. |
2025-02-24 |
2025-02-26 |
rat |