| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danmei Tian, Fangfang Wang, Menglong Duan, Lingyun Cao, Youwei Zhang, Xinsheng Yao, Jinshan Tan. Coumarin Analogues from the Citrus grandis (L.) Osbeck and Their Hepatoprotective Activity. Journal of agricultural and food chemistry. vol 67. issue 7. 2019-03-04. PMID:30689373. |
moreover, compounds 3 and 4 suppressed increases in the levels of alanine transaminase (alt) and aspartate transaminase (ast) in d-galactosamine-treated lo2 cells, further confirming the hepatoprotective effects of these compounds. |
2019-03-04 |
2023-08-13 |
Not clear |
| Thangavelu Lakshmi, Balusamy Sri Renukadevi, Sivanesan Senthilkumar, Perumalsamy Haribalan, R Parameshwari, Rajagopalan Vijayaraghavan, Shanmugam Rajeshkuma. Seed and bark extracts of Acacia catechu protects liver from acetaminophen induced hepatotoxicity by modulating oxidative stress, antioxidant enzymes and liver function enzymes in Wistar rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-01. PMID:30372895. |
when groups treated with acetaminophen, significant increase of liver weight/body weight ratio, liver function enzymes such as alanine aminotransferase (alt), alkaline phosphatase (alp) and aspartate aminotransferase (ast) and decrease of antioxidant enzymes such as glutathione (gsh) and superoxide dismutase (sod) were observed. |
2019-03-01 |
2023-08-13 |
rat |
| Xiangyang Yu, Lili Jia, Kuoqi Yin, Jingshu Lv, Wenli Yu, Hongyin D. Src is Implicated in Hepatic Ischemia Reperfusion-Induced Hippocampus Injury and Long-Term Cognitive Impairment in Young Mice via NMDA Receptor Subunit 2A Activation. Neuroscience. vol 391. 2019-02-27. PMID:30213765. |
serum alanine aminotransferase (alt), aspartate aminotransferase (ast), tumor necrosis factor α (tnf-α), interferon-γ (ifn-γ) and interleukin (il)-6 were increased after reperfusion of 3 days, while pp2 and nvp-aam077 treatment didn't attenuate the changes. |
2019-02-27 |
2023-08-13 |
mouse |
| Huynh Nhu Mai, Garima Sharma, Naveen Sharma, Eun-Joo Shin, Dae-Joong Kim, Duc Toan Pham, Quynh Dieu Trinh, Choon-Gon Jang, Seung Yeol Nah, Ji Hoon Jeong, Hyoung-Chun Ki. Genetic depletion of p53 attenuates cocaine-induced hepatotoxicity in mice. Biochimie. vol 158. 2019-02-27. PMID:30576773. |
cocaine treatment increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels in the serum of mice, signifying hepatic damage. |
2019-02-27 |
2023-08-13 |
mouse |
| Xiao-Jie Mi, Jin-Gang Hou, Shuang Jiang, Zhi Liu, Shan Tang, Xiang-Xiang Liu, Ying-Ping Wang, Chen Chen, Zi Wang, Wei L. Maltol Mitigates Thioacetamide-induced Liver Fibrosis through TGF-β1-mediated Activation of PI3K/Akt Signaling Pathway. Journal of agricultural and food chemistry. vol 67. issue 5. 2019-02-19. PMID:30644744. |
results indicated that taa intraperitoneal injection significantly increased serum activities of alanine aminotransferase (alt) (52.93 ± 13.21 u/l vs 10.22 ± 3.36 u/l) and aspartate aminotransferase (ast) (67.58 ± 25.84 u/l vs 39.34 ± 3.89 u/l); these elevations were significantly diminished by pretreatment with maltol. |
2019-02-19 |
2023-08-13 |
mouse |
| Khizar Hayat, Muhammad Afzal, Muhammad Anjum Aqueel, Sajjad Ali, Muhammad Farhan Saeed, Ahmad Kaleem Qureshi, Muhammad Irfan Ullah, Qaiser M Khan, Muhammad Tayyib Naseem, Umair Ashfaq, Christos A Damala. Insecticide toxic effects and blood biochemical alterations in occupationally exposed individuals in Punjab, Pakistan. The Science of the total environment. vol 655. 2019-02-18. PMID:30469056. |
values of serum cholinesterase (sche) concentration were slightly lower (p > 0.05) in exposed individuals, whereas values of alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) concentration were significantly higher (p < 0.01) in exposed individuals compared with control group. |
2019-02-18 |
2023-08-13 |
Not clear |
| Murat Giriş, Semra Doğru-Abbasoğlu, Merva Soluk-Tekkeşin, Vakur Olgaç, Müjdat Uysa. Effect of betaine treatment on the regression of existing hepatic triglyceride accumulation and oxidative stress in rats fed on high fructose diet. General physiology and biophysics. vol 37. issue 5. 2019-02-15. PMID:30047921. |
hfrd feeding caused insulin resistance, elevated triglyceride (tg) and tumor necrosis factor-alfa (tnf-α) levels, alanine aminotransferase (alt) and aspartate transaminase (ast) activities in serum. |
2019-02-15 |
2023-08-13 |
rat |
| Omnia Hesham Abdelhafez, Michael Atef Fawzy, John Refaat Fahim, Samar Yehia Desoukey, Markus Krischke, Martin J Mueller, Usama Ramadan Abdelmohse. Hepatoprotective potential of Malvaviscus arboreus against carbon tetrachloride-induced liver injury in rats. PloS one. vol 13. issue 8. 2019-02-13. PMID:30138328. |
results showed that the ethyl acetate and dichloromethane fractions significantly alleviated liver injury in rats as indicated by the reduced levels of alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), total bilirubin (tb), and malondialdehyde (mda), along with enhancement of the total antioxidant capacities of their livers, with the maximum effects were recorded by the ethyl acetate fraction. |
2019-02-13 |
2023-08-13 |
rat |
| Hanvit Cha, Seoyoon Lee, Jin Hyup Lee, Jeen-Woo Par. Protective effects of p-coumaric acid against acetaminophen-induced hepatotoxicity in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 121. 2019-02-13. PMID:30149109. |
we found that pca ameliorates aap-induced hepatotoxicity as well as the reduced serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity. |
2019-02-13 |
2023-08-13 |
mouse |
| Jamie L Young, Lu Cai, J Christopher State. Impact of prenatal arsenic exposure on chronic adult diseases. Systems biology in reproductive medicine. vol 64. issue 6. 2019-02-12. PMID:29873257. |
abbreviations: alt: alanine aminotransferase; ami: acute myocardial infarction; ast: aspartate aminotransferase; atsdr: agency for toxic substances and disease registry; cvd: cardiovascular disease; dma: dimethylarsinate; dohad: developmental origins of health and disease; epa: u.s. environmental protection agency; er-α: estrogen receptor alpha; hdl: high-density lipoprotein; homa-ir: homeostatic model assessment of insulin resistance; ias: inorganic arsenic; ldl: low-density lipoprotein; mets: metabolic syndrome; mma: monomethylarsonate; nafld: non-alcoholic fatty liver disease; pnd: postnatal day; ppb: parts per billion; ppm: parts per million; sam: s-adenosylmethionine; usfda: united states food and drug administration. |
2019-02-12 |
2023-08-13 |
Not clear |
| Yashu Xu, Cheng Yang, Shujun Zhang, Jiajun Li, Qing Xiao, Wenxiang Huan. Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation. Biological & pharmaceutical bulletin. vol 41. issue 11. 2019-02-11. PMID:30135326. |
rg1 significantly reduced liver weight, serum alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), liver free fatty acids (ffas) and malondialdehyde (mda) levels, and increased superoxide dismutase (sod) activity. |
2019-02-11 |
2023-08-13 |
mouse |
| Abani Kumar Patar, Anupama Sharma, Donkupar Syiem, Surya Bha. Chlorophyllin supplementation modulates hyperglycemia-induced oxidative stress and apoptosis in liver of streptozotocin-administered mice. BioFactors (Oxford, England). vol 44. issue 5. 2019-02-11. PMID:30303271. |
the hepatoprotective effect of chlorophyllin was confirmed from the decreased activity of aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2019-02-11 |
2023-08-13 |
mouse |
| T B Matshogo, V Mlambo, U Marume, N Sebol. Growth performance, blood parameters, carcass characteristics and meat quality traits in Potchefstroom Koekoek chickens fed Lippia javanica leaf meal. Tropical animal health and production. vol 50. issue 8. 2019-02-08. PMID:29789988. |
diet had no effect on overall fce but significantly (p < 0.05) affected bilirubin, alanine aminotransferase (alt), aspartate transaminase (ast), sodium, potassium, cholesterol and magnesium levels in blood. |
2019-02-08 |
2023-08-13 |
chicken |
| S M Nasrollahi, A Zali, G R Ghorbani, A Kahyani, K A Beauchemi. Short communication: Blood metabolites, body reserves, and feed efficiency of high-producing dairy cows that varied in ruminal pH when fed a high-concentrate diet. Journal of dairy science. vol 102. issue 1. 2019-02-07. PMID:30343904. |
the classification based on rumenocentesis ph revealed that serum activity of aspartate aminotransferase (ast) was greater in cows with low ruminal ph (70.7 u/l) than cows with high (56.6 u/l) and medium (59.9 u/l) ruminal ph. |
2019-02-07 |
2023-08-13 |
Not clear |
| Fabiana Letícia da Silva, Rodrigo Pimenta Del-Rei, Déborah Bittencourt Mothé Fraga, Leonardo Maia Leony, Alina Maria Gonzaga Carlos de Souza, Fred Luciano Neves Santo. Alterations in the lipid profiles and circulating liver enzymes in individuals infected by Schistosoma mansoni. Revista da Sociedade Brasileira de Medicina Tropical. vol 51. issue 6. 2019-02-06. PMID:30517533. |
levels of circulating liver enzymes (gamma-glutamyl transferase [γ-gt], aspartate transaminase [ast], alanine transaminase [alt], and alkaline phosphatase [alp]) and a lipid panel (total cholesterol [col], high-density lipoprotein [hdl], low-density lipoprotein [ldl], very low-density lipoprotein [vldl], and triglycerides [tri]) were evaluated in both infected and non-infected individuals and relative risk was used to measure associations. |
2019-02-06 |
2023-08-13 |
Not clear |
| Muhammad Ibrar, Mir Azam Khan, Abdullah, Muhammad Imra. Evaluation of Paeonia emodi and its gold nanoparticles for cardioprotective and antihyperlipidemic potentials. Journal of photochemistry and photobiology. B, Biology. vol 189. 2019-02-04. PMID:30268952. |
pe.ea 40 (80 mg/kg body weight) significantly reduced the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), creatine phosphokinase (cpk) to 66.07 ± 1.54, 77.08 ± 1.79, 84.86 ± 1.34 and 265.34 ± 4.34 iu/l respectively as compared to iso treated group. |
2019-02-04 |
2023-08-13 |
mouse |
| Salma A El-Marasy, Sally A El Awdan, Reham M Abd-Elsala. Protective role of chrysin on thioacetamide-induced hepatic encephalopathy in rats. Chemico-biological interactions. vol 299. 2019-02-04. PMID:30500344. |
chrysin improved taa-induced motor incoordination as it reduced final falling latency time in rotarod test, ameliorated cognitive deficits in object recognition test (ort) and attenuated serum ammonia, hepatic liver enzymes namely, aspartate aminotransferase (ast) and alanine aminotransferase (alt), reduced malondialdehyde (mda), elevated reduced glutathione (gsh), reduced nuclear factor kappa b (nf-κb), tumor necrosis factor-alpha (tnf-α) and interleukin-6 (il-6) brain contents. |
2019-02-04 |
2023-08-13 |
rat |
| Yongmei Liu, Peiling Zhao, Mingliang Cheng, Lei Yu, Zhuo Cheng, Linda Fan, Chi Che. AST to ALT ratio and arterial stiffness in non-fatty liver Japanese population:a secondary analysis based on a cross-sectional study. Lipids in health and disease. vol 17. issue 1. 2019-02-01. PMID:30509277. |
however, there are fewer investigations of the correlations between the aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio and brachial ankle pulse wave velocity (bapwv). |
2019-02-01 |
2023-08-13 |
Not clear |
| Juliana Aparecida Cerqueira, Wilmer Alejandro Zamora Restan, Mayara Gonçalves Fonseca, Lucas Azevedo Catananti, Maria Luiza Mendes de Almeida, Walter Heinz Feringer Junior, Gener Tadeu Pereira, Aulus Cavalieri Carciofi, Guilherme de Camargo Ferra. Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs. Research in veterinary science. vol 121. 2019-01-31. PMID:30316014. |
here we evaluated the effect of an endurance-training program (etp) on the kinetics of the serum biomarkers: creatine kinase (ck), aspartate aminotransferase (ast), myoglobin, cardiac troponin i (ctni), and creatine kinase isoenzyme mb (ck-mb). |
2019-01-31 |
2023-08-13 |
dog |
| Shanker K Singh, Vivek K Singh, Priyambada Kumari, Udayraj P Nakade, Satish K Gar. Trypanosoma evansi induces detrimental immuno-catabolic alterations and condition like type-2 diabetes in buffaloes. Parasitology international. vol 67. issue 2. 2019-01-30. PMID:29100925. |
moreover, buffaloes with trypanosomosis were found to have markedly elevated levels of serum glucose, total proteins, globulins, urea and aspartate aminotransferase (ast) and markedly lowered levels of serum calcium, total cholesterol levels and albumin/globulin (a/g) ratio as compared to the controls. |
2019-01-30 |
2023-08-13 |
Not clear |