| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yazeed Jamalat, Yaser Gamallat, Pires Sanches Jaceline Gislaine, Abdo Meyiah, Abdullah Shopit, Hailong Li, Bashir Ahmed, Peng Chu, Hongyang Wang, Xiaodong Li, Jinyong Peng, Xiaodong Ma, Zeyao Tan. Phosphocreatine attenuates endoplasmic reticulum stress-mediated hepatocellular apoptosis ameliorates insulin resistance in diabetes model. Biochemical and biophysical research communications. vol 506. issue 3. 2019-05-17. PMID:30366667. |
liver tissues homogenate were analyzed for liver damage markers alanine transaminase (alt), aspartate transaminase (ast). |
2019-05-17 |
2023-08-13 |
rat |
| Yuri Lee, Gil-Saeng Jeong, Kyung-Min Kim, Wonhwa Lee, Jong-Sup Ba. Cudratricusxanthone A attenuates sepsis-induced liver injury via SIRT1 signaling. Journal of cellular physiology. vol 233. issue 7. 2019-05-14. PMID:29226969. |
administration of lps significantly increased mortality, serum levels of alanine transaminase (alt), aspartate transaminase (ast), and serum inflammatory cytokines. |
2019-05-14 |
2023-08-13 |
mouse |
| Hiromi Tabuchi, Hiroshi Maegawa, Kazuyuki Tobe, Ichiro Nakamura, Satoshi Un. Effect of ipragliflozin on liver function in Japanese type 2 diabetes mellitus patients: a subgroup analysis of the STELLA-LONG TERM study (3-month interim results). Endocrine journal. vol 66. issue 1. 2019-05-14. PMID:30393249. |
we evaluated changes in aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyltransferase (γ-gtp), alkaline phosphatase (alp), and fatty liver index (fli) at 3 months of treatment; the proportion of patients with abnormal liver function whose liver function normalized after 3 months of treatment; and correlations between changes in alt levels and efficacy variables/laboratory values. |
2019-05-14 |
2023-08-13 |
Not clear |
| Chen Zhang, Juan Li, Chunlong Hu, Jing Wang, Jianjun Zhang, Zhenzhen Ren, Xinling Song, Le Ji. Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from Hericium erinaceus SG-02 in streptozotocin-induced diabetic mice. Scientific reports. vol 7. issue 1. 2019-05-13. PMID:28883631. |
the supplementation of hips1 and hips2 significantly decreased the blood glucose (glu) levels; suppressed the abnormal elevations of alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), urea nitrogen (bun) and creatinine (cre) levels in serum; improved the antioxidant enzymatic (superoxide dismutase (sod), glutathione peroxidase (gsh-px) and catalase (cat)) activities; and attenuated the pathological damage to these organs. |
2019-05-13 |
2023-08-13 |
mouse |
| A M Al-Otaibi, H F A Al-Balawi, Z Ahmad, E M Sulima. Toxicity bioassay and sub-lethal effects of diazinon on blood profile and histology of liver, gills and kidney of catfish, Clarias gariepinus. Brazilian journal of biology = Revista brasleira de biologia. vol 79. issue 2. 2019-05-10. PMID:30427380. |
glucose level and activity level of aspartate aminotransferase (ast) and alanine aminotransferase (alt) was increased in clarias gariepinus exposed to diazinon. |
2019-05-10 |
2023-08-13 |
Not clear |
| Zheng Li, Haihua Feng, Yue Wang, Bingyu Shen, Ye Tian, Lin Wu, Qiaoling Zhang, Meiyu Jin, Guowen Li. Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling pathways. International immunopharmacology. vol 67. 2019-05-09. PMID:30597292. |
our findings showed that ra could protect c57bl/6 mice from lps/d-galn-induced acute liver injury, which not only reflected on declining aspartate aminotransferase (ast) and alanine aminotransferase (alt) of the serum, but also restrained the phosphorylation of nuclear factor-kappa b (nf-κb), extracellular signal-regulated kinase (erk1/2) and p38 protein expression and the content of tissue myeloperoxidase (mpo) elevation. |
2019-05-09 |
2023-08-13 |
mouse |
| Gang Wang, Ying Liu, Xue-Feng Hou, Zhong-Cheng Ke, Liang Feng, Xiao-Bin Ji. [Prevention effect of Ligusticum chuanxiong extraction against oxidative stress injury induced by myocardial ischemia through activation of Nrf2 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 24. 2019-05-08. PMID:29493155. |
the concentration of malondialdehyde (mda) and activities of serum creatine kinase (ck), lactate dehydrogenase (ldh), aspartate transaminase (ast), superoxide dismutase (sod) and total antioxidant capacity (t-aoc) were measured by colorimetry. |
2019-05-08 |
2023-08-13 |
rat |
| Min Xu, Xi-Ming Zheng, Fang Jiang, Wei-Qiang Qi. MicroRNA-190b regulates lipid metabolism and insulin sensitivity by targeting IGF-1 and ADAMTS9 in non-alcoholic fatty liver disease. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575055. |
knockdown of mir-190b decreased aspartate transaminase (ast), alanine transaminase (alt), triglyceride (tg), and total cholesterol (tc). |
2019-05-08 |
2023-08-13 |
mouse |
| Hossein Zare, Shahram Jamshidi, Mohammad M Dehghan, Mona Saheli, Abbas Piryae. Bone marrow or adipose tissue mesenchymal stem cells: Comparison of the therapeutic potentials in mice model of acute liver failure. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575235. |
furthermore, in the at-tr mice the level of aspartate aminotransferase (ast) and alanine aminotransferase (alt), in some time points were significantly less than those of bm-tr. |
2019-05-08 |
2023-08-13 |
mouse |
| Donald Turbiville, Xiaotang Du, Jacob Yo, Bagi R Jana, Jianli Don. Iron Overload in an HFE Heterozygous Carrier: A Case Report and Literature Review. Laboratory medicine. vol 50. issue 2. 2019-05-08. PMID:30339210. |
her liver function test results showed elevated alanine transaminase (alt) and aspartate aminotransferase (ast) levels. |
2019-05-08 |
2023-08-13 |
Not clear |
| Mary Abiola Okesola, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye, Oluwafemi Adeleke Oj. Effect of Zingiber officinale on some biochemical parameters and cytogenic analysis in lead-induced toxicity in experimental rats. Toxicology mechanisms and methods. vol 29. issue 4. 2019-05-08. PMID:30558515. |
the obtained results show that aspartate aminotransferase (ast), alkaline phosphatase (alp), lipid peroxidation, urea, creatinine, bilirubin, and gamma-glutamyl transferase (ggt) were significantly increased (p < 0.05) and catalase (cat) were reduced progressively in pb alone induced rats. |
2019-05-08 |
2023-08-13 |
human |
| Xue-Liang Li, Lan-Ying Chen, Zi-Yi Guan, Yao Luo, Ya-Ru Cui, Rong-Hua Liu, Feng Shao, Ding-Qing Wan. [Effect of neoflavonoid latifolin isolated from Dalbergia odorifera on acute myocardial ischemia in rats and its mechanism of Nrf2 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 20. 2019-05-03. PMID:29243436. |
further mechanism study showed that latifolin reduced cardiac troponin i(ctni) level, aspartate transaminase(ast) and lactate dehydrogenase(ldh) activities in serum, increased myocardial superoxide dismutase(sod) activity and reduced myocardial malondialdehyde(mda) level, and protected myocardium with less necrosis, infiltration of inflammatory cells and fracture of myocardial fibers. |
2019-05-03 |
2023-08-13 |
rat |
| Ines Amara, Rim Timoumi, Emna Annabi, Fadwa Neffati, Mohamed Fadhel Najjar, Chayma Bouaziz, Salwa Abid-Essef. Di (2-ethylhexyl) phthalate induces cardiac disorders in BALB/c mice. Environmental science and pollution research international. vol 26. issue 8. 2019-05-03. PMID:30659488. |
we assessed the effect of dehp on cardiac injury using biochemical profile (such as aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), creatinine phosphokinase (cpk), total cholesterol (t-chol), triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), and low-density lipoprotein cholesterol (ldl-c)), parameters related to myocardiac oxidative stress, such as malondialdehyde (mda) level, protein carbonyl (pc) concentration, and dna fragmentation. |
2019-05-03 |
2023-08-13 |
mouse |
| Neeraj Kumar, K K Krishnani, Narendra Pratap Sing. Oxidative and Cellular Metabolic Stress of Fish: An Appealing Tool for Biomonitoring of Metal Contamination in the Kolkata Wetland, a Ramsar Site. Archives of environmental contamination and toxicology. vol 76. issue 3. 2019-05-02. PMID:30607445. |
the glycolytic enzymes, such as lactate dehydrogenase (ldh) and malate dehydrogenase (mdh) in liver, gill, and muscle, and protein metabolic enzymes, such as alanine amino transferase (alt) and aspartate amino transferase (ast) in liver, gill, muscle, and kidney, were noticeably higher (p < 0.01) at some of the sampling sites. |
2019-05-02 |
2023-08-13 |
Not clear |
| Rui Liu, Shaopeng Zhang, Wenxuan Ma, Hao Lu, Ji Gao, Xiaojie Gan, Zheng Ju, Jian Gu, Ling L. Age-dependent loss of induced regulatory T cell function exacerbates liver ischemia-reperfusion injury. Molecular immunology. vol 103. 2019-05-01. PMID:30321735. |
in this model, aged-mice suffered more serious injury than young-mice, with higher serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) and higher histological scores from liver biopsies. |
2019-05-01 |
2023-08-13 |
mouse |
| Xiaoyang Zhao, Jon Voutila, Stephanos Ghobrial, Nagy A Habib, Vikash Reeby. Treatment of Liver Cancer by C/EBPA saRNA. Advances in experimental medicine and biology. vol 983. 2019-04-30. PMID:28639200. |
in preclinical models of liver disease, treatment with c/ebpα sarna has shown reduction in tumor volume and improvement in serum markers of essential liver function such as albumin, bilirubin, aspartate aminotransferase (ast), and alanine transaminase (alt). |
2019-04-30 |
2023-08-13 |
human |
| Shanshan Jin, Suwen Jiang, Airong H. Association between obstructive sleep apnea and non-alcoholic fatty liver disease: a systematic review and meta-analysis. Sleep & breathing = Schlaf & Atmung. vol 22. issue 3. 2019-04-30. PMID:29335916. |
the primary purpose of this study was to determine the influence of osa on the levels of liver enzymes including alanine transaminase (alt) and aspartate transaminase (ast). |
2019-04-30 |
2023-08-13 |
human |
| Qianzhen Zhang, Yansong Ge, Hui Li, Ge Bai, Zhihui Jiao, Xiangdong Kong, Weijing Meng, Hongbin Wan. Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs. Research in veterinary science. vol 119. 2019-04-30. PMID:30077949. |
the results showed that hrs treatment significantly decreased serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bilirubin (tbil) activity and tunel-positive cells. |
2019-04-30 |
2023-08-13 |
Not clear |
| Wenjie Wang, Lian Jiang, Yanming Ren, Mingyue Shen, Jianhua Xi. Characterizations and hepatoprotective effect of polysaccharides from Mesona blumes against tetrachloride-induced acute liver injury in mice. International journal of biological macromolecules. vol 124. 2019-04-29. PMID:30502438. |
results indicated that the mbp could remarkably decrease the increased levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the serum caused by tetrachloride (ccl |
2019-04-29 |
2023-08-13 |
mouse |
| Parvin Ghareghani, Mehrnoosh Shanaki, Saeideh Ahmadi, Ali Reza Khoshdel, Neda Rezvan, Reza Meshkani, Maryam Delfan, Sattar Gorgani-Firuzjae. Aerobic endurance training improves nonalcoholic fatty liver disease (NAFLD) features via miR-33 dependent autophagy induction in high fat diet fed mice. Obesity research & clinical practice. vol 12. issue Suppl 2. 2019-04-23. PMID:28163011. |
hfd increased body weight, fasting blood sugar, triglyceride, cholesterol, aspartate aminotransferase (ast), alanine aminotransferase (alt), liver lipogenic genes expression and reduced mir-33 mrna expression and autopahgy pathway while training program reversed them. |
2019-04-23 |
2023-08-13 |
mouse |