| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H J Waldvogel, K Baer, W-P Gai, R T Gilbert, M I Rees, H Mohler, R L M Faul. Differential localization of GABAA receptor subunits within the substantia nigra of the human brain: an immunohistochemical study. The Journal of comparative neurology. vol 506. issue 6. 2008-04-04. PMID:18085588. |
in this study we present the first detailed immunohistochemical investigation on the regional, cellular, and subcellular localisation of alpha(1), alpha(2), alpha(3), beta(2,3), and gamma(2) subunits of the gaba(a)r in the human substantia nigra (sn). |
2008-04-04 |
2023-08-12 |
human |
| César Nava-Asbell, Francisco Paz-Bermudez, David Erlij, Jorge Aceves, Benjamín Florá. GABA(B) receptor activation inhibits dopamine D1 receptor-mediated facilitation of [(3)H]GABA release in substantia nigra pars reticulata. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17868750. |
gaba(b) receptors inhibit and dopamine d1 receptors stimulate the release of gaba from striatal terminals in the pars reticulata of the substantia nigra. |
2008-01-14 |
2023-08-12 |
rat |
| César Nava-Asbell, Francisco Paz-Bermudez, David Erlij, Jorge Aceves, Benjamín Florá. GABA(B) receptor activation inhibits dopamine D1 receptor-mediated facilitation of [(3)H]GABA release in substantia nigra pars reticulata. Neuropharmacology. vol 53. issue 5. 2008-01-14. PMID:17868750. |
here we have studied the interaction between both classes of receptors by exploring the effect of gaba(b) receptors upon the stimulation of depolarization-induced [(3)h]gaba release induced by the activation of d1 receptors in slices of the pars reticulata of the rat substantia nigra. |
2008-01-14 |
2023-08-12 |
rat |
| Martina Fantin, Matteo Marti, Yves P Auberson, Michele Morar. NR2A and NR2B subunit containing NMDA receptors differentially regulate striatal output pathways. Journal of neurochemistry. vol 103. issue 6. 2008-01-08. PMID:17986236. |
nvp-aam077 also prevented the nmda-induced surge in gaba release in the globus pallidus, whereas ro 25-6981 attenuated it in the substantia nigra. |
2008-01-08 |
2023-08-12 |
Not clear |
| T Goetz, A Arslan, W Wisden, P Wulf. GABA(A) receptors: structure and function in the basal ganglia. Progress in brain research. vol 160. 2007-09-28. PMID:17499107. |
here we place the focus on gaba(a) receptor expression in the basal ganglia: striatum, globus pallidus, substantia nigra and subthalamic nucleus, where, in addition to the standard alpha1beta2/3gamma2 receptor subtype, significant levels of other subunits (alpha2, alpha3, alpha4, gamma1, gamma3 and delta) are expressed in some nuclei. |
2007-09-28 |
2023-08-12 |
Not clear |
| Alice Guyon, Jean-Louis Naho. Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity. Journal of molecular endocrinology. vol 38. issue 3. 2007-09-18. PMID:17339399. |
in various neuronal populations (ca1 neurons of the hippocampus, granular and purkinje cells of the cerebellum, melanin-concentrating hormone neurons of the lateral hypothalamus, vasopressinergic neurons of the supraoptic and the paraventricular nucleus of the hypothalamus, and dopaminergic neurons of the substantia nigra), sdf-1alpha can modulate the activity of neurons by multiple regulatory pathways including and often combining: (i) modulation of voltage-dependent channels (sodium, potassium, and calcium), (ii) activation of the g-protein-activated inward rectifier potassium current, and (iii) increase in neurotransmitter release (gamma-amino butyric acid (gaba), glutamate, and dopamine), often through ca-dependent mechanisms. |
2007-09-18 |
2023-08-12 |
Not clear |
| Karla A Mark, Maria S Quinton, Shelley J Russek, Bryan K Yamamot. Dynamic changes in vesicular glutamate transporter 1 function and expression related to methamphetamine-induced glutamate release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 25. 2007-07-19. PMID:17581970. |
meth-induced increases in cortical vglut1 mrna, as well as striatal vglut1 and gapdh, are gaba(a) receptor-dependent because they are blocked by gaba(a) receptor antagonism in the substantia nigra. |
2007-07-19 |
2023-08-12 |
Not clear |
| H Wang, J Katz, P Dagostino, J-J Soghomonia. Unilateral 6-hydroxydopamine lesion of dopamine neurons and subchronic L-DOPA administration in the adult rat alters the expression of the vesicular GABA transporter in different subsets of striatal neurons and in the substantia nigra, pars reticulata. Neuroscience. vol 145. issue 2. 2007-06-26. PMID:17218060. |
unilateral 6-hydroxydopamine lesion of dopamine neurons and subchronic l-dopa administration in the adult rat alters the expression of the vesicular gaba transporter in different subsets of striatal neurons and in the substantia nigra, pars reticulata. |
2007-06-26 |
2023-08-12 |
rat |
| Hideki Shimada, Daisuke Uta, Junichi Nabekura, Megumu Yoshimur. Involvement of Kv channel subtypes on GABA release in mechanically dissociated neurons from the rat substantia nigra. Brain research. vol 1141. 2007-06-01. PMID:17300765. |
involvement of kv channel subtypes on gaba release in mechanically dissociated neurons from the rat substantia nigra. |
2007-06-01 |
2023-08-12 |
rat |
| Eva de Lago, Silvia Ortega-Gutiérrez, José A Ramos, Maria L López Rodríguez, Javier Fernández-Rui. Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions. Life sciences. vol 80. issue 10. 2007-03-20. PMID:17173937. |
in the case of the basal ganglia, ucm707 reduced gaba content in the substantia nigra but only at longer (5 or 12 h) times after administration. |
2007-03-20 |
2023-08-12 |
rat |
| Eva de Lago, Silvia Ortega-Gutiérrez, José A Ramos, Maria L López Rodríguez, Javier Fernández-Rui. Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions. Life sciences. vol 80. issue 10. 2007-03-20. PMID:17173937. |
so, changes in gaba transmission (decrease) were restricted to the substantia nigra, but did not appear in other regions, whereas dopamine transmission was also altered in the caudate-putamen and the nucleus accumbens. |
2007-03-20 |
2023-08-12 |
rat |
| Christian R Lee, James M Teppe. Morphological and physiological properties of parvalbumin- and calretinin-containing gamma-aminobutyric acidergic neurons in the substantia nigra. The Journal of comparative neurology. vol 500. issue 5. 2007-02-22. PMID:17177263. |
evidence for the existence of different populations of gamma-aminobutyric acid (gaba)-ergic neurons in the substantia nigra comes partially from anatomical studies, which have shown there to be little if any overlap between the calcium-binding proteins parvalbumin and calretinin in individual neurons, suggesting that these may represent neuronal subtypes with distinct electrophysiological and/or anatomical properties. |
2007-02-22 |
2023-08-12 |
rat |
| Noriko Yamamoto, R Christopher Pierce, Jean-Jacques Soghomonia. Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata. Brain research. vol 1123. issue 1. 2007-02-01. PMID:17027936. |
subchronic administration of l-dopa to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced gaba release in the substantia nigra, pars reticulata. |
2007-02-01 |
2023-08-12 |
rat |
| Noriko Yamamoto, R Christopher Pierce, Jean-Jacques Soghomonia. Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata. Brain research. vol 1123. issue 1. 2007-02-01. PMID:17027936. |
the present study, using in vivo microdialysis, investigated the effects of a single or subchronic administration of l-dopa to adult rats with a unilateral 6-ohda lesion of dopamine neurons on gaba release in the substantia nigra, pars reticulata (snr). |
2007-02-01 |
2023-08-12 |
rat |
| Trond Myhrer, Nga H T Nguyen, Siri Enger, Pål Aa. Anticonvulsant effects of GABA(A) modulators microinfused into area tempestas or substantia nigra in rats exposed to soman. Archives of toxicology. vol 80. issue 8. 2006-12-14. PMID:16525814. |
anticonvulsant effects of gaba(a) modulators microinfused into area tempestas or substantia nigra in rats exposed to soman. |
2006-12-14 |
2023-08-12 |
rat |
| Trond Myhrer, Nga H T Nguyen, Siri Enger, Pål Aa. Anticonvulsant effects of GABA(A) modulators microinfused into area tempestas or substantia nigra in rats exposed to soman. Archives of toxicology. vol 80. issue 8. 2006-12-14. PMID:16525814. |
in the present study, gaba(a) modulating drugs (1 microl) were microinfused bilaterally into the seizure controlling substrates, substantia nigra (sn) or area tempestas (at), of rats subjected to seizures induced systemically by soman (100 microg/kg). |
2006-12-14 |
2023-08-12 |
rat |
| Giuseppe Di Giovanni, Vincenzo Di Matteo, Massimo Pierucci, Arcangelo Benigno, Ennio Esposit. Serotonin involvement in the basal ganglia pathophysiology: could the 5-HT2C receptor be a new target for therapeutic strategies? Current medicinal chemistry. vol 13. issue 25. 2006-12-05. PMID:17073648. |
in fact, serotonergic terminals have been reported to make synaptic contacts with dopamine (da)-containing neurons and gamma-aminobutyric acid (gaba)-containing neurons in the striatum, globus pallidus, subthalamus and substantia nigra. |
2006-12-05 |
2023-08-12 |
human |
| José García Dopico, Tomás González-Hernández, Ingrid Morales Pérez, Isabel Gómez García, Antonio Milena Abril, José Obeso Inchausti, Manuel Rodríguez Día. Glycine release in the substantia nigra: Interaction with glutamate and GABA. Neuropharmacology. vol 50. issue 5. 2006-07-06. PMID:16337663. |
glycine release in the substantia nigra: interaction with glutamate and gaba. |
2006-07-06 |
2023-08-12 |
rat |
| Wolfgang Löscher, Marko Schirmer, Christian Freichel, Manuela Gerner. Distribution of GABAergic neurons in the striatum of amygdala-kindled rats: an immunohistochemical and in situ hybridization study. Brain research. vol 1083. issue 1. 2006-07-03. PMID:16545783. |
our previous finding of reduced gad and gaba levels in synaptosomes isolated from the substantia nigra of kindled rats together with the present observation of increased density of gabaergic striatal interneurons in such rats suggest that kindling affects the regulation of the gabaergic projections from the striatum to the substantia nigra rather than directly damaging gabaergic neurons in the striatum. |
2006-07-03 |
2023-08-12 |
rat |
| Vanessa A Fitsanakis, Catherine Au, Keith M Erikson, Michael Aschne. The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation. Neurochemistry international. vol 48. issue 6-7. 2006-06-09. PMID:16513220. |
the initial symptoms of manganism are likely due to the involvement of the globus pallidus, a region rich in gamma-aminobutyric acid (gaba) projections, while those of parkinson's disease are related to the degeneration of the substantia nigra, a dopaminergic nucleus. |
2006-06-09 |
2023-08-12 |
Not clear |