| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michel Barrot, Susan R Sesack, François Georges, Marco Pistis, Simon Hong, Thomas C Jho. Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 41. 2013-01-03. PMID:23055478. |
the tvta/rmtg sends dense gaba projections to vta and substantia nigra neurons. |
2013-01-03 |
2023-08-12 |
Not clear |
| I C Kilpatrick, J W Neal, R C Pearson, T P Powel. Lesions of the Cerebral Cortex and Caudate-Putamen Enhance GABA Function in the Rat Superior Colliculus. The European journal of neuroscience. vol 3. issue 10. 2012-10-02. PMID:12106255. |
unilateral lesions of the rat frontal cortex were made either alone or in combination with the caudate-putamen in order to examine (a) their morphological influence on the substantia nigra and (b) their neurochemical influence on gaba function in the superior colliculus. |
2012-10-02 |
2023-08-12 |
rat |
| I C Kilpatrick, J W Neal, R C Pearson, T P Powel. Lesions of the Cerebral Cortex and Caudate-Putamen Enhance GABA Function in the Rat Superior Colliculus. The European journal of neuroscience. vol 3. issue 10. 2012-10-02. PMID:12106255. |
such evoked gaba release from ipsilateral tectal slices was significantly reduced (- 25%) by unilateral lesions of the substantia nigra, a structure that is known to provide gaba-containing inputs to the tectum. |
2012-10-02 |
2023-08-12 |
rat |
| M P de la Mora, K Fuxe, T Hökfelt, A Ljungdah. Evidence for a nerve impulse-dependent GABA accumulation in the substantia nigra after treatment with gamma-glutamylhydrazide. Neuroscience letters. vol 5. issue 1-2. 2012-10-02. PMID:19604974. |
evidence for a nerve impulse-dependent gaba accumulation in the substantia nigra after treatment with gamma-glutamylhydrazide. |
2012-10-02 |
2023-08-12 |
rat |
| M P de la Mora, K Fuxe, T Hökfelt, A Ljungdah. Evidence for a nerve impulse-dependent GABA accumulation in the substantia nigra after treatment with gamma-glutamylhydrazide. Neuroscience letters. vol 5. issue 1-2. 2012-10-02. PMID:19604974. |
gaba accumulation was studied in the substantia nigra after treatment with l-glutamic acid-gamma-hydrazide (gah) in rats 3 h following hemisection at the posterior hypothalamic level. |
2012-10-02 |
2023-08-12 |
rat |
| W Löscher, M Vetter, F Müller, G Böhme, G Stoltenburg-Didinge. Development of a synaptosomal model to determine drug-induced in vivo changes in GABA-levels of nerve endings in 11 brain regions of the rat. Neurochemistry international. vol 6. issue 4. 2012-10-02. PMID:20488067. |
in contrast, vpa induced significant synaptosomal gaba increases in olfactory bulbs, hypothalamus, superior and inferior colliculus, substantia nigra, and cerebellum. |
2012-10-02 |
2023-08-12 |
rat |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
although the adminstration of mptp (50 mg/kg, once a day for 5 days) to male mice of dd strain did not induce the changes in choline and acethylcholine contents in the striatum, a decrement of gaba content in the midbrain, especially in the substantia nigra, was found in addition to a significant decrease of dopamine content in the striatum. |
2012-10-02 |
2023-08-12 |
mouse |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
this decrement in gaba content was accompanied by a decrease of turnover rate of gaba in the substantia nigra. |
2012-10-02 |
2023-08-12 |
mouse |
| T Kuriyama, J Taguchi, K Kuriyam. Functional alterations in striatal cholinergic and striato-nigral gabaergic neurons following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration. Neurochemistry international. vol 16. issue 3. 2012-10-02. PMID:20504575. |
furthermore, it was found that mptp treatment induced an increase of the gaba(a) receptor-benzodiazepine receptor-chloride channel complex in the substantia nigra in addition to that of dopaminergic d(2) receptor in the striatum. |
2012-10-02 |
2023-08-12 |
mouse |
| P Westerling, S Lindgren, B J Meyerso. Behavioural and biochemical effects of muscimol in ethanolamine O-sulphate-treated rats. Journal of psychopharmacology (Oxford, England). vol 3. issue 3. 2012-10-02. PMID:22282896. |
muscimol decreased the accumulation of gaba in the substantia nigra after 8 days but not after 30 days of eos treatment, indicating that receptor adaptation might have occurred. |
2012-10-02 |
2023-08-12 |
rat |
| P Westerling, S Lindgren, B J Meyerso. The behavioural effects of chronic elevation of rat brain GABA by ethanolamine O-sulphate. Journal of psychopharmacology (Oxford, England). vol 3. issue 3. 2012-10-02. PMID:22282897. |
this effect was accompanied by an accumulation of gaba in the substantia nigra and the corpus striatum. |
2012-10-02 |
2023-08-12 |
rat |
| Melissa L Perreault, Theresa Fan, Mohammed Alijaniaram, Brian F O'Dowd, Susan R Georg. Dopamine D1-D2 receptor heteromer in dual phenotype GABA/glutamate-coexpressing striatal medium spiny neurons: regulation of BDNF, GAD67 and VGLUT1/2. PloS one. vol 7. issue 3. 2012-08-20. PMID:22428025. |
activation of the d1r-d2r heteromer in these neurons resulted in the simultaneous, but differential regulation of proteins involved in gaba and glutamate production or vesicular uptake in the nucleus accumbens (nac), ventral tegmental area (vta), caudate putamen and substantia nigra (sn). |
2012-08-20 |
2023-08-12 |
Not clear |
| Leonora E Long, Rose Chesworth, Xu-Feng Huang, Alexander Wong, Adena Spiro, Iain S McGregor, Jonathon C Arnold, Tim Kar. Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice. PloS one. vol 7. issue 4. 2012-08-20. PMID:22509273. |
long-term cbd (50 mg/kg) also selectively increased gaba(a) receptor binding in the granular retrosplenial cortex in nrg1 tm het mice and reduced 5-ht(2a) binding in the substantia nigra in wt mice. |
2012-08-20 |
2023-08-12 |
mouse |
| Alicja Lerner, Anto Bagic, Janine M Simmons, Zoltan Mari, Omer Bonne, Ben Xu, Diane Kazuba, Peter Herscovitch, Richard E Carson, Dennis L Murphy, Wayne C Drevets, Mark Hallet. Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome. Brain : a journal of neurology. vol 135. issue Pt 6. 2012-07-27. PMID:22577221. |
in addition, the gaba(a) receptor binding was increased in the bilateral substantia nigra, left periaqueductal grey, right posterior cingulate cortex and bilateral cerebellum. |
2012-07-27 |
2023-08-12 |
Not clear |
| Lixiang Ma, Baoyang Hu, Yan Liu, Scott Christopher Vermilyea, Huisheng Liu, Lu Gao, Yan Sun, Xiaoqing Zhang, Su-Chun Zhan. Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell stem cell. vol 10. issue 4. 2012-07-03. PMID:22424902. |
transplantation of these human forebrain gaba neurons and their progenitors, but not spinal gaba cells, into the striatum of quinolinic acid-lesioned mice results in generation of large populations of darpp32(+) gaba neurons, which project to the substantia nigra as well as receiving glutamatergic and dopaminergic inputs, corresponding to correction of motor deficits. |
2012-07-03 |
2023-08-12 |
mouse |
| Ghazaleh Samoudi, Hans Nissbrandt, Mayank B Dutia, Filip Bergquis. Noisy galvanic vestibular stimulation promotes GABA release in the substantia nigra and improves locomotion in hemiparkinsonian rats. PloS one. vol 7. issue 1. 2012-05-14. PMID:22238601. |
noisy galvanic vestibular stimulation promotes gaba release in the substantia nigra and improves locomotion in hemiparkinsonian rats. |
2012-05-14 |
2023-08-12 |
rat |
| Shengyuan Ding, Wei Wei, Fu-Ming Zho. Molecular and functional differences in voltage-activated sodium currents between GABA projection neurons and dopamine neurons in the substantia nigra. Journal of neurophysiology. vol 106. issue 6. 2012-04-16. PMID:21880943. |
molecular and functional differences in voltage-activated sodium currents between gaba projection neurons and dopamine neurons in the substantia nigra. |
2012-04-16 |
2023-08-12 |
Not clear |
| Simone Bido, Matteo Marti, Michele Morar. Amantadine attenuates levodopa-induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels. Journal of neurochemistry. vol 118. issue 6. 2011-11-01. PMID:21740438. |
levodopa also evoked aims expression and a gaba surge (∼2-fold) selectively in the substantia nigra of dyskinetic rats. |
2011-11-01 |
2023-08-12 |
mouse |
| M S Nandhu, Jes Paul, Korah P Kuruvila, Pretty M Abraham, Sherin Antony, C S Paulos. Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson's rat: functional recovery with bone marrow cells, serotonin and GABA. Molecular and cellular biochemistry. vol 353. issue 1-2. 2011-10-18. PMID:21384157. |
the aim of this study is to assess the glutamate and nmda receptor functional regulation and motor performance of 6-hydroxydopamine-induced parkinson's rat and the effects of serotonin (5-ht), gamma aminobutyric acid (gaba) and bone marrow cells supplementation infused intranigrally to substantia nigra individually and in combination. |
2011-10-18 |
2023-08-12 |
rat |
| B Lin, S Levy, A P Raval, M A Perez-Pinzon, R A Defazi. Forebrain ischemia triggers GABAergic system degeneration in substantia nigra at chronic stages in rats. Cardiovascular psychiatry and neurology. vol 2010. 2011-07-14. PMID:20981346. |
following neuronal loss of 30-40% in central and dorsolateral striatum at day 3, neuronal damage in the substantia nigra (sn) was assessed at 4-8 weeks using immunohistochemistry for glutamate decarboxylase 67 (gad67), vesicular gaba transporter (vgat), and calretinin (cr). |
2011-07-14 |
2023-08-12 |
rat |