| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Claus, J S Kim, M E Kornhuber, Y S Ah. [Effect of ethanol on the neurotransmitters glutamate and GABA]. Archiv fur Psychiatrie und Nervenkrankheiten. vol 232. issue 2. 1983-03-11. PMID:6130753. |
an increase in gaba was found in the striatum, hippocampus, and substantia nigra, 8 or 12 h after the last ingestion of ethanol, this being masked by injection of barbiturate. |
1983-03-11 |
2023-08-12 |
rat |
| A G Chapman, K Riley, M C Evans, B S Meldru. Acute effects of sodium valproate and gamma-vinyl GABA on regional amino acid metabolism in the rat brain: incorporation of 2-[14C]glucose into amino acids. Neurochemical research. vol 7. issue 9. 1983-02-25. PMID:6817155. |
after valproate administration the gaba level increases only in the cortex; aspartic acid concentration decreases in the cortex and hippocampus, and glutamic acid decreases in the hippocampus and striatum and increases in the cortex and cerebellum. |
1983-02-25 |
2023-08-12 |
rat |
| A Bosio, L Lucchi, P F Spano, M Trabucch. Central toxic effects of chronic ethanol treatment: actions on GABA and benzodiazepine recognition sites. Toxicology letters. vol 13. issue 1-2. 1983-02-14. PMID:6294924. |
when [3h]gaba binding in the cerebellum, striatum and hippocampus was increased, [3h]diazepam binding remained unchanged in the same areas. |
1983-02-14 |
2023-08-12 |
Not clear |
| D Claus, J S Kim, J C Aschoff, H H Kornhube. [Glutamate and GABA concentration in the brain and cerebrospinal fluid of rats treated with phosphatidylcholine]. Archiv fur Psychiatrie und Nervenkrankheiten. vol 232. issue 1. 1983-01-19. PMID:6128966. |
in tissue from frontal cortex, striatum, substantia nigra, cerebellar cortex no significant differences between treated and untreated animals were found in glutamate or gaba concentrations. |
1983-01-19 |
2023-08-12 |
rat |
| A R Green, K Sant, J M Bowdler, P J Cowe. Further evidence for a relationship between changes in GABA concentration in rat brain and enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shock. Neuropharmacology. vol 21. issue 10. 1983-01-19. PMID:7145036. |
pretreatment with these antagonists of gamma-aminobutyric acid (gaba) also abolished the rise in the concentration of gaba in the corpus striatum, normally seen after repeated ecs. |
1983-01-19 |
2023-08-12 |
rat |
| T C Howerton, M J Marks, A C Collin. Norepinephrine, gamma-aminobutyric acid, and choline reuptake kinetics and the effects of ethanol in long-sleep and short-sleep mice. Substance and alcohol actions/misuse. vol 3. issue 1-2. 1982-12-16. PMID:7135160. |
kinetic analysis revealed no significant differences between lines in affinity (km) or maximal velocity (vmax) for norepinephrine and gaba measured in cortex and cerebellum or for choline measured in striatum and cortex. |
1982-12-16 |
2023-08-12 |
mouse |
| S P Sivam, T Nabeshima, I K H. An analysis of GABA receptor changes in the discrete regions of mouse brain after acute and chronic treatments with morphine. Journal of neurochemistry. vol 39. issue 4. 1982-12-02. PMID:6288864. |
the effects of morphine on the affinity and distribution of gaba receptors in the mouse regions (striatum, medulla, diencephalon, cortex, and cerebellum) were investigated in relation to: (a) acute administration, (b) chronic administration (tolerance), (c) precipitated withdrawal by naloxone, an opiate antagonist, and (d) abrupt withdrawal for 8 and 24 h. the alterations in the affinity as reflected by the dissociation constant (kd) and the number of receptors (bmax) in the synaptic membranes obtained from controls and various treatments were determined by radioligand binding assay using [3h]muscimol as a ligand. |
1982-12-02 |
2023-08-12 |
mouse |
| P L Woo. Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat. The Journal of pharmacology and experimental therapeutics. vol 222. issue 3. 1982-10-29. PMID:6286931. |
in contrast, parenteral 4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol, kojic amine and aminoxyacetic acid inhibit the nigrostriatal pathway acting both within the substantia nigra and on presynaptic nigrostriatal gaba receptors in the striatum. |
1982-10-29 |
2023-08-12 |
rat |
| P L Woo. Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat. The Journal of pharmacology and experimental therapeutics. vol 222. issue 3. 1982-10-29. PMID:6286931. |
a unique interneuronal gaba receptor also appears to be present in the striatum which is activated by intrastriatal muscimol but not 4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol or kojic amine. |
1982-10-29 |
2023-08-12 |
rat |
| S R Vincent, H Kimura, E G McGee. A histochemical study of GABA-transaminase in the efferents of the pallidum. Brain research. vol 241. issue 1. 1982-10-12. PMID:7104702. |
previous results on the localization of gaba-transaminase in efferents of the striatum indicated that such histochemistry may be a useful adjunct for the demonstration of gaba pathways. |
1982-10-12 |
2023-08-12 |
Not clear |
| E Scarnati, C Pacitt. Neuronal responses to iontophoretically applied dopamine, glutamate, and GABA of identified dopaminergic cells in the rat substantia nigra after kainic acid-induced destruction of the striatum. Experimental brain research. vol 46. issue 3. 1982-09-24. PMID:6124446. |
neuronal responses to iontophoretically applied dopamine, glutamate, and gaba of identified dopaminergic cells in the rat substantia nigra after kainic acid-induced destruction of the striatum. |
1982-09-24 |
2023-08-12 |
rat |
| K Aoki, Y Kuroiw. Effect of acute and chronic phenobarbital treatment on GABA and other amino acids contents in seven regions of the rat brain. Journal of pharmacobio-dynamics. vol 5. issue 2. 1982-09-10. PMID:6124592. |
chronic phenobarbital treatment resulted in the decrease of gaba content in the cerebral cortex, midbrain, hypothalamus, striatum and hippocampus. |
1982-09-10 |
2023-08-12 |
rat |
| J W Villiger, K M Taylor, P D Gluckma. Characteristics of type 1 and type 2 benzodiazepine receptors in the ovine brain. Pharmacology, biochemistry, and behavior. vol 16. issue 3. 1982-07-19. PMID:6281813. |
displacement of 3h-diazepam by cl218,872 was enhanced by 10(-5) m gaba in the striatum (at 200 nm and 800 nm cl218,872) and cerebellum (at 200 nm cl218,872). |
1982-07-19 |
2023-08-12 |
rat |
| D A Kendall, B S McEwen, S J Enn. The influence of ACTH and corticosterone on [3H]GABA receptor binding in rat brain. Brain research. vol 236. issue 2. 1982-06-24. PMID:6279241. |
the increase in gaba receptor binding in the midbrain occurs within 72 h of surgery, whereas that found in the corpus striatum becomes evident between 1 and 2 weeks later. |
1982-06-24 |
2023-08-12 |
rat |
| H G Lloyd, M N Perkins, T W Ston. Ethylenediamine as a specific releasing agent of gamma-aminobutyric acid in rat striatal slices. Journal of neurochemistry. vol 38. issue 4. 1982-05-21. PMID:7082461. |
following incubation with [14c]gamma-aminobutyric acid (gaba) or [3h]dopamine, slices of rat striatum were superfused with media containing 36 mm k+ or ethylenediamine (eda), 1 or 5 mm. |
1982-05-21 |
2023-08-12 |
rat |
| S Simler, S Puglisi-Allegra, P Mande. gamma-Aminobutyric acid in brain areas of isolated aggressive or non-aggressive inbred strains of mice. Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:7199186. |
social isolation induced a clear increase of aggressive responses only in the dba/2 strain and a decrease of gaba levels in septum, striatum, olfactory bulb and posterior colliculus in both the c57bl/6 and in the dba/2 strains. |
1982-04-12 |
2023-08-12 |
mouse |
| S Simler, S Puglisi-Allegra, P Mande. gamma-Aminobutyric acid in brain areas of isolated aggressive or non-aggressive inbred strains of mice. Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:7199186. |
dba mice when compared to c57 mice showed significantly lower levels of gaba in olfactory bulb and striatum. |
1982-04-12 |
2023-08-12 |
mouse |
| G Bernardi, M G Marciani, P Stanzione, E Cherubini, N Mercur. Evidence in favour of GABA as an inhibitory transmitter in the rat striatum. Advances in biochemical psychopharmacology. vol 30. 1982-04-12. PMID:7331937. |
evidence in favour of gaba as an inhibitory transmitter in the rat striatum. |
1982-04-12 |
2023-08-12 |
rat |
| Z Kleinrok, L Tursk. Biochemical consequences of kainic acid injection into the lateral brain ventricle in rat. Acta biochimica Polonica. vol 28. issue 2. 1982-03-13. PMID:6119862. |
a decreased level of gamma-aminobutyric acid was found in the striatum and cerebellum at 480 h following injection of ka. |
1982-03-13 |
2023-08-12 |
rat |
| K Gale, M Cas. Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications. Molecular and cellular biochemistry. vol 39. 1982-02-22. PMID:6118827. |
dynamic utilization of gaba in substantia nigra: regulation by dopamine and gaba in the striatum, and its clinical and behavioral implications. |
1982-02-22 |
2023-08-12 |
Not clear |