| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Moloney, B E Leonar. Pre-natal and post-natal effects of alcohol in the rat--II. Changes in gamma-aminobutyric acid concentration and adenosine triphosphatase activity in the brain. Alcohol and alcoholism (Oxford, Oxfordshire). vol 19. issue 2. 1985-01-18. PMID:6149760. |
the effects of chronic alcohol administration during the pre-natal and/or post-natal period on concentration of gamma aminobutyric acid (gaba) in the amygdaloid cortex and striatum and on activities of na+, k+- and mg2+ -activated adenosine triphosphatases (atpases) in the mid-brain and hippocampus were studied. |
1985-01-18 |
2023-08-12 |
rat |
| I Hanin, M R Krigman, R B Mailma. Central neurotransmitter effects of organotin compounds: trials, tribulations and observations. Neurotoxicology. vol 5. issue 2. 1984-12-26. PMID:6150454. |
tet had no effect on any of the substances measured whereas tmt significantly decreased gamma-aminobutyric acid and dopamine levels, but only in hippocampus and striatum, respectively. |
1984-12-26 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. |
1984-12-20 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
the unaltered gaba level in the substantia nigra is compatible with the existence of gabaergic interneurons in the striatum, which are inhibited by the afferent dopaminergic innervation to the striatum. |
1984-12-20 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
by contrast, we found in an earlier investigation with sulpiride, an atypical neuroleptic drug, a changed glutamate level in the striatum and the csf and an unaltered gaba level. |
1984-12-20 |
2023-08-12 |
rat |
| V K Pozdeev, G M Gracheva, A P Il'i. [Effect of electrical stimulation in the kindling regimen on brain mediator systems in rats]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 70. issue 7. 1984-12-13. PMID:6149159. |
30 days of the stimulation led to a decrease of dopamine, norepinephrine, taurine and glutamine in hippocampus; fall of the level of gomovanillic acid, norepinephrine, as well as increase of glutamic acid, glutamine, gaba and taurine in striatum; decrease of glutamine and increase of gaba and glycine in cerebellum. |
1984-12-13 |
2023-08-12 |
rat |
| V K Pozdeev, G M Gracheva, A P Il'i. [Effect of electrical stimulation in the kindling regimen on brain mediator systems in rats]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 70. issue 7. 1984-12-13. PMID:6149159. |
the rise of glutamic acid, glutamine, gaba and taurine in striatum occurred as the result of increased activity of these systems. |
1984-12-13 |
2023-08-12 |
rat |
| C Coudray-Lucas, M Prioux-Guyonneau, H Sentenac, Y Cohen, J Wepierr. Effects of physostigmine, paraoxon and soman on brain GABA level and metabolism. Acta pharmacologica et toxicologica. vol 55. issue 2. 1984-12-05. PMID:6496115. |
the effects of sublethal doses of physostigmine, paraoxon and soman on gaba levels and metabolism were studied in small rat brain areas (hypothalamus, striatum, cerebellum, rest of the brain). |
1984-12-05 |
2023-08-12 |
rat |
| V Petkov, V Markovsk. Participation of serotoninergic, GABA-ergic and opiate mechanisms in the genesis of amphetamine stereotypy. Acta physiologica et pharmacologica Bulgarica. vol 10. issue 2. 1984-11-20. PMID:6237549. |
it is considered that the results obtained show that da released from the nigrostriatal pathway exercises its typical inhibitory influence on the striatum, by stimulating 5-ht, gaba and opiate neurons situated in nucleus caudatus. |
1984-11-20 |
2023-08-12 |
rat |
| C Reavill, S Muscatt, P N Leigh, P Jenner, C D Marsde. Enhanced GABA function in the angular complex (lateral periaqueductal grey matter and adjacent reticular formation) alters the postural component of striatal- or nigral-derived circling. Experimental brain research. vol 56. issue 1. 1984-10-19. PMID:6468558. |
manipulation of gaba function in the angular complex alters circling behaviour initiated from the striatum or substantia nigra by altering the postural component without affecting the locomotor response of the animals. |
1984-10-19 |
2023-08-12 |
Not clear |
| B Scatton, A Serrano, J P Rivot, T Nishikaw. Inhibitory GABAergic influence on striatal serotonergic transmission exerted in the dorsal raphe as revealed by in vivo voltammetry. Brain research. vol 305. issue 2. 1984-09-20. PMID:6331602. |
reduced the amplitude of the signal from the striatum, while injection of gamma-acetylenic gaba (200 mg/kg i.p.) |
1984-09-20 |
2023-08-12 |
rat |
| B Scatton, A Serrano, J P Rivot, T Nishikaw. Inhibitory GABAergic influence on striatal serotonergic transmission exerted in the dorsal raphe as revealed by in vivo voltammetry. Brain research. vol 305. issue 2. 1984-09-20. PMID:6331602. |
in contrast, local injection of the gaba receptor antagonists, bicuculline (1 and 10 micrograms) or r5135 (0.05 microgram), failed to affect the peak amplitude in the striatum. |
1984-09-20 |
2023-08-12 |
rat |
| B Scatton, A Serrano, J P Rivot, T Nishikaw. Inhibitory GABAergic influence on striatal serotonergic transmission exerted in the dorsal raphe as revealed by in vivo voltammetry. Brain research. vol 305. issue 2. 1984-09-20. PMID:6331602. |
finally, electrolytic lesion of the habenular nuclei completely blocked the diminution of the signal from striatum induced by an intradorsal raphé infusion of gaba (100 micrograms). |
1984-09-20 |
2023-08-12 |
rat |
| M Erecińska, D Nelson, D F Wilson, I A Silve. Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion. Brain research. vol 304. issue 1. 1984-09-12. PMID:6146383. |
the levels of amino acids in 6 regions of the brain (cortex, hippocampus, striatum, diencephalon, stem and cerebellum) were determined during an ischemic insult of 30 min and after recovery periods of up to 10 h. the results were analyzed in two groups: putative neurotransmitters (gaba, aspartate, glutamate, taurine, glycine and alanine) and non-neurotransmitters. |
1984-09-12 |
2023-08-12 |
rat |
| T Nishikawa, B Scatto. The inhibitory GABAergic influence on striatal serotonergic neurons depends upon the habenulo-raphe pathways. Brain research. vol 304. issue 1. 1984-09-12. PMID:6331579. |
bilateral lesion of the habenular nuclei by electrocoagulation or by local ibotenate injection antagonized the ability of the gaba agonist agents progabide and depamide (given systemically) or of gaba (applied locally into the dorsal raphé) to diminish 5-htp accumulation in the rat striatum. |
1984-09-12 |
2023-08-12 |
rat |
| O Gandolfi, D L Cheney, J S Hong, E Cost. On the neurotoxicity of chlordecone: a role for gamma-aminobutyric acid and serotonin. Brain research. vol 303. issue 1. 1984-08-21. PMID:6203618. |
chlordecone reduced the rate of gaba accumulation in striatum, but not in cerebellum, brainstem or hippocampus. |
1984-08-21 |
2023-08-12 |
rat |
| W Löscher, M Vette. Relationship between drug-induced increases of GABA levels in discrete brain areas and different pharmacological effects in rats. Biochemical pharmacology. vol 33. issue 12. 1984-07-13. PMID:6428417. |
in all the other regions studied (corpus striatum, thalamus, hypothalamus, superior and inferior colliculus, substantia nigra, pons, medulla, cerebellum), increases in gaba were less marked and, at least in part, maximum increases (30-60% over control) were already reached by 1-2 hr. |
1984-07-13 |
2023-08-12 |
rat |
| W Löscher, M Vette. Relationship between drug-induced increases of GABA levels in discrete brain areas and different pharmacological effects in rats. Biochemical pharmacology. vol 33. issue 12. 1984-07-13. PMID:6428417. |
produced significant increases in gaba levels only in the cortex, olfactory bulb, corpus striatum, hypothalamus and cerebellum, maximum effects (15-35%) being already reached 5-30 min after vpa administration. |
1984-07-13 |
2023-08-12 |
rat |
| J Hedner, T Hedner, P Wessberg, J Jonaso. An analysis of the mechanism by which gamma-aminobutyric acid depresses ventilation in the rat. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 56. issue 4. 1984-07-11. PMID:6725063. |
the gaba content measured 45 min after aoaa administration was significantly increased in the whole brain, the hemispheres, striatum, and lower spinal cord regions. |
1984-07-11 |
2023-08-12 |
rat |
| M Orosco, J Bremond, C Jacquot, Y Cohe. Fenfluramine and brain transmitters in the obese Zucker rat. Neuropharmacology. vol 23. issue 2A. 1984-05-30. PMID:6201773. |
levels of noradrenaline (na), dopamine (da), 5-hydroxytryptamine (5-ht) and gamma-aminobutyric acid (gaba) and their metabolism were assayed in the hypothalamus, striatum, medulla-oblongata pons and remainder of the brain. |
1984-05-30 |
2023-08-12 |
rat |