| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Leader, B K Koe, A Weissma. GABA-like actions of levonantradol. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:6271832. |
the interaction of levonantradol and its pharmacologically less active (+)-enantiomer with gabaergic mechanisms was studied in several in vivo systems: (1) rat cerebellar cgmp, based on the inverse relationship of gabaergic activity and cgmp levels; (2) convulsions elicited by 3-mercaptopropionic acid, an inhibitor of gaba synthesis; and (3) activated dopamine synthesis in rat striatum following blockade of dopamine receptors. |
1982-01-09 |
2023-08-12 |
mouse |
| J B Penney, H S Pan, A B Young, K A Frey, G W Daut. Quantitative autoradiography of [3H]muscimol binding in rat brain. Science (New York, N.Y.). vol 214. issue 4524. 1982-01-09. PMID:6272394. |
unilateral gamma-aminobutyric acid receptor supersensitivity was observed in the substantia nigra pars reticulata after production of localized lesions of the ipsilateral corpus striatum. |
1982-01-09 |
2023-08-12 |
rat |
| S R Vincent, H Kimura, E G McGee. The histochemical localization of GABA-transaminase in the efferents of the striatum. Brain research. vol 222. issue 1. 1982-01-09. PMID:7296268. |
the striatum is known to contain gaba neurons projecting to the globus pallidus, entopeduncular nucleus and substantia nigra. |
1982-01-09 |
2023-08-12 |
Not clear |
| S R Vincent, H Kimura, E G McGee. The histochemical localization of GABA-transaminase in the efferents of the striatum. Brain research. vol 222. issue 1. 1982-01-09. PMID:7296268. |
following lesions of striatal neurons with kainic acid, we have observed a decrease in the histochemically detectable activity of gaba-transaminase, the enzyme responsible for gaba catabolism, in both the striatum and in those areas to which it is known to send gaba projections. |
1982-01-09 |
2023-08-12 |
Not clear |
| P T Wong, E G McGee. Postnatal changes of GABAergic and glutamatergic parameters. Brain research. vol 227. issue 4. 1981-10-29. PMID:7260657. |
the present results also indicate that there may exist in the immature striatum some glioblasts which might accumulate beta-alanine but not gaba. |
1981-10-29 |
2023-08-12 |
rat |
| J Sawynok, F S Labell. GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices. European journal of pharmacology. vol 70. issue 2. 1981-10-14. PMID:6266839. |
gaba potentiates the potassium-evoked release of methionine-enkephalin (me) from slices of rat corpus striatum. |
1981-10-14 |
2023-08-12 |
rat |
| J Z Nowak, B Bielkiewic. Effect of histamine H1- and H2-receptor agonists on gamma-aminobutyric acid (GABA) content in hypothalamus and striatum of the rat brain. Archivum immunologiae et therapiae experimentalis. vol 28. issue 6. 1981-09-22. PMID:6455100. |
effect of histamine h1- and h2-receptor agonists on gamma-aminobutyric acid (gaba) content in hypothalamus and striatum of the rat brain. |
1981-09-22 |
2023-08-12 |
rat |
| J Z Nowak, B Bielkiewic. Effect of histamine H1- and H2-receptor agonists on gamma-aminobutyric acid (GABA) content in hypothalamus and striatum of the rat brain. Archivum immunologiae et therapiae experimentalis. vol 28. issue 6. 1981-09-22. PMID:6455100. |
50-250 microgram of dimaprit and 100 microgram of 4-methylhistamine decreased gaba level after 30 min (by approximately 20%) in the hypothalamus, but not in the striatum of the rat brain. |
1981-09-22 |
2023-08-12 |
rat |
| J A van der Heyden, K Venema, P Lebrun, J B Sebens, J Kor. Release of endogenous GABA from the rat brain: methodological aspects and the effects of catecholamines. Advances in biochemical psychopharmacology. vol 29. 1981-09-15. PMID:6266211. |
the release of endogenous gaba from the striatum, the substantia nigra and the ventral thalamic nucleus was measured in push-pull canula perfusates with high pressure chromatography and fluorimetric detection. |
1981-09-15 |
2023-08-12 |
rat |
| J A van der Heyden, K Venema, P Lebrun, J B Sebens, J Kor. Release of endogenous GABA from the rat brain: methodological aspects and the effects of catecholamines. Advances in biochemical psychopharmacology. vol 29. 1981-09-15. PMID:6266211. |
dopamine (da), noradrenaline (na), isoprenaline, clonidine and dibutyryl cyclic amp decreased the gaba release from the striatum. |
1981-09-15 |
2023-08-12 |
rat |
| J Scheel-Krüger, G Magelund, M Oliana. The role of GABA in the basal ganglia and limbic system for behaviour. Advances in biochemical psychopharmacology. vol 29. 1981-09-15. PMID:7020365. |
we have recently obtained evidence that gaba in the striato-entopeduncular, striato-nigral and the pallido-subthalamic descending gabaergic pathways is mediator of dopamine dependent behaviours related to dopamine receptor stimulation in striatum. |
1981-09-15 |
2023-08-12 |
rat |
| J Scheel-Krüger, G Magelund, M Oliana. The role of GABA in the basal ganglia and limbic system for behaviour. Advances in biochemical psychopharmacology. vol 29. 1981-09-15. PMID:7020365. |
gaba receptor stimulation in ep, stn and snr mediates according to this new hypothesis the efferent output of striatum (see fig. |
1981-09-15 |
2023-08-12 |
rat |
| F Moroni, C Bianchi, S Tanganelli, G Moneti, L Bean. The release of gamma-aminobutyric acid, glutamate, and acetylcholine from striatal slices: a mass fragmentographic study. Journal of neurochemistry. vol 36. issue 5. 1981-08-20. PMID:6113268. |
these results are consistent with a possible neurotransmitter role of ach and gaba in the striatum and show some differences in the ionic mechanisms underlying gaba and ach release. |
1981-08-20 |
2023-08-12 |
Not clear |
| K Gal. Relationship between the presence of dopaminergic neurons and GABA receptors in substantia nigra: effects of lesions. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6112044. |
the latter process may result from a decrease in nigral gaba transmission secondary to the complete loss of dopaminergic synaptic activity in striatum. |
1981-07-23 |
2023-08-12 |
rat |
| C Ennis, B Co. GABA enhancement of [3H]dopamine release from slices of rat striatum: dependence on slice size. European journal of pharmacology. vol 70. issue 3. 1981-07-20. PMID:7227457. |
gaba enhancement of [3h]dopamine release from slices of rat striatum: dependence on slice size. |
1981-07-20 |
2023-08-12 |
rat |
| C Ennis, B Co. GABA enhancement of [3H]dopamine release from slices of rat striatum: dependence on slice size. European journal of pharmacology. vol 70. issue 3. 1981-07-20. PMID:7227457. |
the effect of gaba on potassium-evoked tritium release from two sizes of ribbon of rat striatum previously loaded with [3h]dopamine was studied. |
1981-07-20 |
2023-08-12 |
rat |
| P A Kelly, J McCulloc. Heterogeneous depression of glucose utilization in the caudate nucleus by GABA agonists. Brain research. vol 209. issue 2. 1981-07-09. PMID:6261871. |
although glucose utilization was reduced throughout the striatum following gaba agonists, the magnitude of the reductions in the lateral portion of the nucleus were markedly greater than in other portions of the caudate nucleus. |
1981-07-09 |
2023-08-12 |
rat |
| M K Ticku, R D Huffma. The effects of acute and chronic morphine administration on GABA receptor binding. European journal of pharmacology. vol 68. issue 2. 1981-05-28. PMID:6258932. |
acute morphine (25 mg/kg) administration produced a decrease in the gaba binding in cerebellum, cortex and striatum. |
1981-05-28 |
2023-08-12 |
rat |
| M K Ticku, R D Huffma. The effects of acute and chronic morphine administration on GABA receptor binding. European journal of pharmacology. vol 68. issue 2. 1981-05-28. PMID:6258932. |
however, in rats which were physically dependent, as indicated by naloxone-precipitated withdrawal, gaba binding was decreased significantly in cerebellum and striatum, relative to chronic morphine treatment or placebo pellet controls. |
1981-05-28 |
2023-08-12 |
rat |
| P J Norris, C C Smith, J De Belleroche, H F Bradford, P G Mantle, A J Thomas, R H Penn. Actions of tremorgenic fungal toxins on neurotransmitter release. Journal of neurochemistry. vol 34. issue 1. 1981-03-17. PMID:6108984. |
penitrem a pretreatment increased the spontaneous release of aspartate, glutamate, and gaba by 68%, 62%, and 100%, respectively, from sheep corpus striatum synaptosomes but did not alter the synthesis and release of dopamine in this tissue. |
1981-03-17 |
2023-08-12 |
rat |