| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gail D Zeevalk, Lawrence Manzino, Patricia K Sonsall. Protection of malonate-induced GABA but not dopamine loss by GABA transporter blockade in rat striatum. Experimental neurology. vol 176. issue 1. 2002-08-16. PMID:12093096. |
to determine if gaba transporter blockade during mitochondrial impairment can protect neurons in vivo as compared with in vitro studies, rats received a stereotaxic infusion of malonate (2 micromol) into the left striatum to induce a metabolic stress. |
2002-08-16 |
2023-08-12 |
rat |
| Gail D Zeevalk, Lawrence Manzino, Patricia K Sonsall. Protection of malonate-induced GABA but not dopamine loss by GABA transporter blockade in rat striatum. Experimental neurology. vol 176. issue 1. 2002-08-16. PMID:12093096. |
these data show that gaba transporter blockade during mitochondrial impairment in the striatum provides protection to gabaergic neurons. |
2002-08-16 |
2023-08-12 |
rat |
| Norbert Balon, Badreddine Kriem, Michel Weiss, Jean-Claude Rostai. Indirect presynaptic modulation of striatal dopamine release by GABA(B) receptors in the rat substantia nigra. Neuroscience letters. vol 325. issue 1. 2002-07-10. PMID:12023061. |
this suggests that gaba(b) receptors in the snr, but not the snc, may play a major role in the control of nigrostriatal dopamine (da) activity and the release of da in the striatum. |
2002-07-10 |
2023-08-12 |
rat |
| Anthony R West, H Moore, A A Grac. Direct examination of local regulation of membrane activity in striatal and prefrontal cortical neurons in vivo using simultaneous intracellular recording and microdialysis. The Journal of pharmacology and experimental therapeutics. vol 301. issue 3. 2002-06-19. PMID:12023513. |
in the striatum, local perfusion of the gamma-aminobutyric acid(a) receptor antagonist bicuculline rapidly depolarized neurons and increased spontaneous spike activity. |
2002-06-19 |
2023-08-12 |
Not clear |
| Toshihiko Momiyam. [Calcium channel subtypes mediating central synaptic transmission]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 119. issue 4. 2002-06-18. PMID:11979729. |
a recent study has demonstrated that activation of presynaptic dopamine d2-like receptors selectively block n-type ca2+ channels to reduce gaba release onto cholinergic interneurons in the rat striatum. |
2002-06-18 |
2023-08-12 |
rat |
| Robert T Kennedy, Jonathan E Thompson, Thomas W Vickro. In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis. Journal of neuroscience methods. vol 114. issue 1. 2002-04-04. PMID:11850038. |
extracellular levels of glutamate (glu), aspartate (asp), glycine (gly), phosphoethanolamine (pea), and gamma-aminobutyric acid (gaba) were measured in the striatum of anesthetized rats using a novel sampling approach in which extracellular fluid (ecf) was removed at 1-50 nl/min using a fused silica capillary tube with 18-40 microm inner diameter and a outer diameter of 90 microm. |
2002-04-04 |
2023-08-12 |
rat |
| A Berthele, S Platzer, S Weis, B Conrad, T R Töll. Expression of GABA(B1) and GABA(B2) mRNA in the human brain. Neuroreport. vol 12. issue 15. 2002-02-19. PMID:11711869. |
in the human striatum gaba(b1) mrna was expressed in moderate amounts, whereas the gaba(b2) mrna signal was not clearly above background. |
2002-02-19 |
2023-08-12 |
human |
| Lucien M Levy, Mark Hallet. Impaired brain GABA in focal dystonia. Annals of neurology. vol 51. issue 1. 2002-01-31. PMID:11782988. |
reduced gaba in the striatum is consistent with striatal dysfunction since gaba is a principal neurotransmitter in that region. |
2002-01-31 |
2023-08-12 |
human |
| Marise B Parent, Sangeeta Master, Shauna Kashlub, Glen B Bake. Effects of the antidepressant/antipanic drug phenelzine and its putative metabolite phenylethylidenehydrazine on extracellular gamma-aminobutyric acid levels in the striatum. Biochemical pharmacology. vol 63. issue 1. 2002-01-23. PMID:11754874. |
effects of the antidepressant/antipanic drug phenelzine and its putative metabolite phenylethylidenehydrazine on extracellular gamma-aminobutyric acid levels in the striatum. |
2002-01-23 |
2023-08-12 |
rat |
| B Dean, T Hussai. Studies on dopaminergic and GABAergic markers in striatum reveals a decrease in the dopamine transporter in schizophrenia. Schizophrenia research. vol 52. issue 1-2. 2001-12-18. PMID:11595397. |
this study does not readily add weight to the hypothesis that changes in the interaction between dopamine and gaba in the striatum are important in the pathology of schizophrenia. |
2001-12-18 |
2023-08-12 |
human |
| Y Tamaru, S Nomura, N Mizuno, R Shigemot. Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites. Neuroscience. vol 106. issue 3. 2001-12-07. PMID:11591452. |
double labeling revealed that the vast majority of mglur3 in presynaptic elements is not closely associated with glutamate and gaba release sites in the striatum and thalamus, respectively. |
2001-12-07 |
2023-08-12 |
mouse |
| A N Schoffelmeer, G Wardeh, L J Vanderschure. Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens. Synapse (New York, N.Y.). vol 42. issue 2. 2001-12-04. PMID:11574945. |
we recently showed that activation of n-methyl-d-aspartate (nmda) as well as dopamine (da) d1 receptors in rat striatum causes tetrodotoxin-insensitive transporter-dependent gaba release. |
2001-12-04 |
2023-08-12 |
rat |
| A I Esquifino, R Seara, E Fernández-Rey, A Lafuent. Alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (GABA) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Archives of toxicology. vol 75. issue 3. 2001-11-01. PMID:11409534. |
alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (gaba) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. |
2001-11-01 |
2023-08-12 |
rat |
| A I Esquifino, R Seara, E Fernández-Rey, A Lafuent. Alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (GABA) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Archives of toxicology. vol 75. issue 3. 2001-11-01. PMID:11409534. |
this work examines changes of gamma aminobutyric acid (gaba) and taurine contents in the hypothalamus, striatum and prefrontal cortex of the rat after an alternate schedule of cadmium administration. |
2001-11-01 |
2023-08-12 |
rat |
| A I Esquifino, R Seara, E Fernández-Rey, A Lafuent. Alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (GABA) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Archives of toxicology. vol 75. issue 3. 2001-11-01. PMID:11409534. |
in control rats gaba content decreased with age in the median eminence and in anterior, mediobasal and posterior hypothalamus, prefrontal cortex and the striatum. |
2001-11-01 |
2023-08-12 |
rat |
| A I Esquifino, R Seara, E Fernández-Rey, A Lafuent. Alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (GABA) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Archives of toxicology. vol 75. issue 3. 2001-11-01. PMID:11409534. |
in pubertal rats treated with cadmium from 30 to 60 days of life, gaba content significantly decreased in all brain regions except in the striatum. |
2001-11-01 |
2023-08-12 |
rat |
| A I Esquifino, R Seara, E Fernández-Rey, A Lafuent. Alternate cadmium exposure differentially affects the content of gamma-aminobutyric acid (GABA) and taurine within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats. Archives of toxicology. vol 75. issue 3. 2001-11-01. PMID:11409534. |
these results suggest that cadmium differentially affects gaba and taurine contents within the hypothalamus, median eminence, striatum and prefrontal cortex as a function of age. |
2001-11-01 |
2023-08-12 |
rat |
| X C Tang, M R Rao, G Hu, H Wan. Alterations of amino acid levels from striatum, hippocampus, and cerebral cortex induced by global cerebral ischemia in gerbil. Acta pharmacologica Sinica. vol 21. issue 9. 2001-10-18. PMID:11501164. |
to investigate global cerebral ischemia-induced alterations in the levels of glutamate, aspartate, gamma-aminobutyric acid (gaba), glutamine, glycine, and taurine from hippocampus, striatum, and cerebral cortex in gerbils. |
2001-10-18 |
2023-08-12 |
Not clear |
| A J Cooper, I M Stanfor. Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABA(A) IPSCs in vitro. Neuropharmacology. vol 41. issue 1. 2001-09-20. PMID:11445186. |
in sagittal slices, single shock electrical stimulation in the striatum evoked gaba(a) inhibitory postsynaptic currents (ipscs), which were inhibited by dopamine in a dose-dependent manner (0.3-30 microm) with an ic(50) value of 0.7 microm. |
2001-09-20 |
2023-08-12 |
Not clear |
| G D Zeevalk, L P Bernard, L Manzino, P K Sonsall. Differential sensitivity of mesencephalic neurons to inhibition of phosphatase 2A. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504786. |
consistent with in vitro findings, infusion of 32 to 320 pmol of oka into the left striatum of rats caused a dose-dependent loss of striatal dopamine without any loss of gaba 1 week following infusion. |
2001-09-13 |
2023-08-12 |
rat |